Proteintech

LCA5 Polyclonal Antibody

FIGURE: 1 / 1

LCA5 Antibody (19333-1-AP) in WB

HeLa cells were subjected to SDS PAGE followed by western blot with 19333-1-AP ( LCA5 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Product Details

19333-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

Assay-dependent

View 4 publications 4 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LCA5 Fusion Protein Ag5140 (4-283 aa encoded by BC050327)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The MW of this protein is 80 kDa, and this antibody specifically recognizes the 80 kDa protein.

Immunogen sequence: RAGSPGTDQ EREAGKHHYS YSSDFETPQS SGRSSLVSSS PASVRRKNPK RQTSDGQVHH QAPRKPSPKG LPNRKGVRVG FRSQSLNREP LRKDTDLVTK RILSARLLKI NELQNEVSEL QVKLAELLKE NKSLKRLQYR QEKALNKFED AENEISQLIF RHNNEITALK ERLRKSQEKE RATEKRVKDT ESELFRTKFS LQKLKEISEA RHLPERDDLA KKLVSAELKL DDTERRIKEL SKNLELSTNS FQRQLLAERK RAYEAHDENK VLQKEVQRLY H (4-283 aa encoded by BC050327)

Target Information

Might be involved in minus end-directed microtubule transport.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The interaction between LC8 and LCA5 reveals a novel oligomerization function of LC8 in the ciliary-centrosome system.

Scientific reports

Szaniszló T,Fülöp M,Pajkos M,Erdős G,Kovács RÁ,Vadászi H,Kardos J,Dosztányi Z

Fri Sep 16 00:00:00 EDT 2022

The interaction between LC8 and LCA5 reveals a novel oligomerization function of LC8 in the ciliary-centrosome system.

Scientific reports

Szaniszló T,Fülöp M,Pajkos M,Erdős G,Kovács RÁ,Vadászi H,Kardos J,Dosztányi Z

Fri Sep 16 00:00:00 EDT 2022

The interaction between LC8 and LCA5 reveals a novel oligomerization function of LC8 in the ciliary-centrosome system.

Scientific reports

Szaniszló T,Fülöp M,Pajkos M,Erdős G,Kovács RÁ,Vadászi H,Kardos J,Dosztányi Z

Fri Sep 16 00:00:00 EDT 2022

Tissue- and isoform-specific protein complex analysis with natively processed bait proteins.

Journal of proteomics

Beyer T,Klose F,Kuret A,Hoffmann F,Lukowski R,Ueffing M,Boldt K

Sat Jan 16 00:00:00 EST 2021

Treatment Potential for LCA5-Associated Leber Congenital Amaurosis.

Investigative ophthalmology & visual science

Uyhazi KE,Aravand P,Bell BA,Wei Z,Leo L,Serrano LW,Pearson DJ,Shpylchak I,Pham J,Vasireddy V,Bennett J,Aleman TS

Mon May 11 00:00:00 EDT 2020

Amelioration of Neurosensory Structure and Function in Animal and Cellular Models of a Congenital Blindness.

Molecular therapy : the journal of the American Society of Gene Therapy

Song JY,Aravand P,Nikonov S,Leo L,Lyubarsky A,Bennicelli JL,Pan J,Wei Z,Shpylchak I,Herrera P,Bennett DJ,Commins N,Maguire AM,Pham J,den Hollander AI,Cremers FPM,Koenekoop RK,Roepman R,Nishina P,Zhou S,Pan W,Ying GS,Aleman TS,de Melo J,McNamara I,Sun J,Mills J,Bennett J

Wed Jun 06 00:00:00 EDT 2018

Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration.

Human molecular genetics

Karlstetter M,Sorusch N,Caramoy A,Dannhausen K,Aslanidis A,Fauser S,Boesl MR,Nagel-Wolfrum K,Tamm ER,Jägle H,Stoehr H,Wolfrum U,Langmann T

Wed Oct 01 00:00:00 EDT 2014

Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration.

Human molecular genetics

Karlstetter M,Sorusch N,Caramoy A,Dannhausen K,Aslanidis A,Fauser S,Boesl MR,Nagel-Wolfrum K,Tamm ER,Jägle H,Stoehr H,Wolfrum U,Langmann T

Wed Oct 01 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: Leber congenital amaurosis 5; Leber congenital amaurosis 5 protein; Lebercilin

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Gene Aliases: C6orf152; LCA5

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UniProt ID: (Human) Q86VQ0

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Entrez Gene ID: (Human) 167691

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Function(s)

protein binding protein complex binding

Process(es)

protein transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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LCA5 Polyclonal Antibody

LCA5 Antibody (19333-1-AP) in WB

Product Details

19333-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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