Product References
In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination.
Biological research
Qin Y,Zhou Y,Wang K,Gu J,Xiong Z,Zhang W,Chen Y
Fri Apr 21 00:00:00 EDT 2023
Effect of Total Sphingomyelin Synthase Activity on Low Density Lipoprotein Catabolism in Mice.
bioRxiv : the preprint server for biology
Li Z,He M,Chen G,Worgall TS,Jiang XC
Tue Feb 07 00:00:00 EST 2023
Efficient prime editing in mouse brain, liver and heart with dual AAVs.
Nature biotechnology
Davis JR,Banskota S,Levy JM,Newby GA,Wang X,Anzalone AV,Nelson AT,Chen PJ,Hennes AD,An M,Roh H,Randolph PB,Musunuru K,Liu DR
Thu May 04 00:00:00 EDT 2023
Noncanonical atherosclerosis as the driving force in tricuspid aortic valve associated aneurysms - A trace collection.
Journal of lipid research
Doppler C,Messner B,Mimler T,Schachner B,Rezk M,Ganhör C,Wechselberger C,Müller M,Puh S,Pröll J,Arbeithuber B,Müller T,Zierer A,Bernhard D
Wed Mar 01 00:00:00 EST 2023
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Guo HH,Shen HR,Wang LL,Luo ZG,Zhang JL,Zhang HJ,Gao TL,Han YX,Jiang JD
Sat Jul 01 00:00:00 EDT 2023
Pseurotin A Validation as a Metastatic Castration-Resistant Prostate Cancer Recurrence-Suppressing Lead via PCSK9-LDLR Axis Modulation.
Marine drugs
Abdelwahed KS,Siddique AB,Ebrahim HY,Qusa MH,Mudhish EA,Rad AH,Zerfaoui M,Abd Elmageed ZY,El Sayed KA
Tue Mar 28 00:00:00 EDT 2023
Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer.
iScience
Yang QC,Wang S,Liu YT,Song A,Wu ZZ,Wan SC,Li HM,Sun ZJ
Fri Jun 16 00:00:00 EDT 2023
Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer.
iScience
Yang QC,Wang S,Liu YT,Song A,Wu ZZ,Wan SC,Li HM,Sun ZJ
Fri Jun 16 00:00:00 EDT 2023
Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer.
iScience
Yang QC,Wang S,Liu YT,Song A,Wu ZZ,Wan SC,Li HM,Sun ZJ
Fri Jun 16 00:00:00 EDT 2023
Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer.
iScience
Yang QC,Wang S,Liu YT,Song A,Wu ZZ,Wan SC,Li HM,Sun ZJ
Fri Jun 16 00:00:00 EDT 2023
Cholesterol-Lowering Activity of Vitisin A Is Mediated by Inhibiting Cholesterol Biosynthesis and Enhancing LDL Uptake in HepG2 Cells.
International journal of molecular sciences
Yuan Y,Zhu Y,Li Y,Li X,Jiao R,Bai W
Tue Feb 07 00:00:00 EST 2023
Commercial lipoprotein-deficient sera differ in iron content.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Laffin JM,Shao W,Espenshade PJ
Wed Feb 01 00:00:00 EST 2023
Resveratrol Modulates the Redox Response and Bile Acid Metabolism to Maintain the Cholesterol Homeostasis in Fish Megalobrama amblycephala Offered a High-Carbohydrate Diet.
Antioxidants (Basel, Switzerland)
Ge Y,Zhang L,Chen W,Sun M,Liu W,Li X
Tue Jan 03 00:00:00 EST 2023
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
EMBO reports
Chen Y,Wu X,Zhang J,Pan G,Wang X,Guo X,Wang J,Cui X,Gao H,Cheng M,Yang J,Zhang C,Jiang F
Thu Feb 03 00:00:00 EST 2022
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
EMBO reports
Chen Y,Wu X,Zhang J,Pan G,Wang X,Guo X,Wang J,Cui X,Gao H,Cheng M,Yang J,Zhang C,Jiang F
Thu Feb 03 00:00:00 EST 2022
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
EMBO reports
Chen Y,Wu X,Zhang J,Pan G,Wang X,Guo X,Wang J,Cui X,Gao H,Cheng M,Yang J,Zhang C,Jiang F
Thu Feb 03 00:00:00 EST 2022
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
EMBO reports
Chen Y,Wu X,Zhang J,Pan G,Wang X,Guo X,Wang J,Cui X,Gao H,Cheng M,Yang J,Zhang C,Jiang F
Thu Feb 03 00:00:00 EST 2022
Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways.
International journal of endocrinology
Yuefeng Y,Zhiqi L,Yi C,Keyu Z,Heng W,Yuying W,Ningjian W,Yuetian Y,Xinjie G,Yihao Z,Yingli L,Fangzhen X
Sat Jul 16 00:00:00 EDT 2022
Oryzanol Attenuates High Fat and Cholesterol Diet-Induced Hyperlipidemia by Regulating the Gut Microbiome and Amino Acid Metabolism.
Journal of agricultural and food chemistry
Yan S,Chen J,Zhu L,Guo T,Qin D,Hu Z,Han S,Zhou Y,Akan OD,Wang J,Luo F,Lin Q
Wed Jun 01 00:00:00 EDT 2022
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
Food & function
He H,Liu M,He R,Zhao W
Mon Oct 03 00:00:00 EDT 2022
Increased LDL receptor by SREBP2 or SREBP2-induced lncRNA LDLR-AS promotes triglyceride accumulation in fish.
iScience
Cao X,Fang W,Li X,Wang X,Mai K,Ai Q
Fri Jul 15 00:00:00 EDT 2022
Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity.
Brain : a journal of neurology
Perelroizen R,Philosof B,Budick-Harmelin N,Chernobylsky T,Ron A,Katzir R,Shimon D,Tessler A,Adir O,Gaoni-Yogev A,Meyer T,Krivitsky A,Shidlovsky N,Madi A,Ruppin E,Mayo L
Wed Sep 14 00:00:00 EDT 2022
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
JCI insight
Li L,Zhong S,Li R,Liang N,Zhang L,Xia S,Xu X,Chen X,Chen S,Tao Y,Yin H
Fri Apr 08 00:00:00 EDT 2022
Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin.
Cancer research
Ho GY,Kyran EL,Bedo J,Wakefield MJ,Ennis DP,Mirza HB,Vandenberg CJ,Lieschke E,Farrell A,Hadla A,Lim R,Dall G,Vince JE,Chua NK,Kondrashova O,Upstill-Goddard R,Bailey UM,Dowson S,Roxburgh P,Glasspool RM,Bryson G,Biankin AV,Cooke SL,Ratnayake G,McNally O,Traficante N,DeFazio A,Weroha SJ,Bowtell DD,McNeish IA,Papenfuss AT,Scott CL,Barker HE
Fri Dec 02 00:00:00 EST 2022
Co-delivery of EGCG and lycopene via a pickering double emulsion induced synergistic hypolipidemic effect.
Food & function
Wang Q,Wang L,Tian W,Song M,Cao Y,Xiao J
Mon Mar 21 00:00:00 EDT 2022
Fused-ring α-pyrones from intramolecular C-H activation and their lipids-lowering activity associated with LXR-IDOL-LDLR axis regulation.
European journal of medicinal chemistry
Mao Y,Li J,Tang C,Ma B,Xu Z,Ke C,Feng L,Zhang H,Yao S,Dai HX,Ye Y
Thu Dec 15 00:00:00 EST 2022
MT5-MMP promotes neuroinflammation, neuronal excitability and Aβ production in primary neuron/astrocyte cultures from the 5xFAD mouse model of Alzheimer's disease.
Journal of neuroinflammation
Pilat D,Paumier JM,García-González L,Louis L,Stephan D,Manrique C,Khrestchatisky M,Di Pasquale E,Baranger K,Rivera S
Fri Mar 11 00:00:00 EST 2022
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
Journal of ethnopharmacology
Zhao CZ,Jiang W,Zhu YY,Wang CZ,Zhong WH,Wu G,Chen J,Zhu MN,Wu QL,Du XL,Luo YY,Li M,Wang HL,Zhao H,Ma QG,Zhong GY,Wei RR
Fri Mar 25 00:00:00 EDT 2022
LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis.
Clinical and translational medicine
Shi X,Chen Y,Liu Q,Mei X,Liu J,Tang Y,Luo R,Sun D,Ma Y,Wu W,Tu W,Zhao Y,Xu W,Ke Y,Jiang S,Huang Y,Zhang R,Wang L,Chen Y,Xia J,Pu W,Zhu H,Zuo X,Li Y,Xu J,Gao F,Wei D,Chen J,Yin W,Wang Q,Dai H,Yang L,Guo G,Cui J,Song N,Zou H,Zhao S,Distler JHW,Jin L,Wang J
Sat Jan 01 00:00:00 EST 2022
Engineered Red Blood Cell Membrane-Coating Salidroside/Indocyanine Green Nanovesicles for High-Efficiency Hypoxic Targeting Phototherapy of Triple-Negative Breast Cancer.
Advanced healthcare materials
Pan Y,He Y,Zhao X,Pan Y,Meng X,Lv Z,Hu Z,Mou X,Cai Y
Thu Sep 01 00:00:00 EDT 2022
The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes.
Journal of lipid research
Khan TG,Ginsburg D,Emmer BT
Mon Aug 01 00:00:00 EDT 2022
The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes.
Journal of lipid research
Khan TG,Ginsburg D,Emmer BT
Mon Aug 01 00:00:00 EDT 2022
The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes.
Journal of lipid research
Khan TG,Ginsburg D,Emmer BT
Mon Aug 01 00:00:00 EDT 2022
GPI-anchored ligand-BioID2-tagging system identifies Galectin-1 mediating Zika virus entry.
iScience
Gao SS,Shi R,Sun J,Tang Y,Zheng Z,Li JF,Li H,Zhang J,Leng Q,Xu J,Chen X,Zhao J,Sy MS,Feng L,Li C
Thu Dec 22 00:00:00 EST 2022
GPI-anchored ligand-BioID2-tagging system identifies Galectin-1 mediating Zika virus entry.
iScience
Gao SS,Shi R,Sun J,Tang Y,Zheng Z,Li JF,Li H,Zhang J,Leng Q,Xu J,Chen X,Zhao J,Sy MS,Feng L,Li C
Thu Dec 22 00:00:00 EST 2022
An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency.
Journal of nanobiotechnology
Zhang R,Bu T,Cao R,Li Z,Wang C,Huang B,Wei M,Yuan L,Yang G
Sat Oct 29 00:00:00 EDT 2022
Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial.
Cell metabolism
Wang J,Zhao J,Yan C,Xi C,Wu C,Zhao J,Li F,Ding Y,Zhang R,Qi S,Li X,Liu C,Hou W,Chen H,Wang Y,Wu D,Chen K,Jiang H,Huang H,Liu H
Tue May 03 00:00:00 EDT 2022
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
New PCSK9 inhibitor miR-552-3p reduces LDL-C via enhancing LDLR in high fat diet-fed mice.
Pharmacological research
Ma N,Fan L,Dong Y,Xu X,Yu C,Chen J,Ren J
Sat May 01 00:00:00 EDT 2021
Relationships between di-(2-ethylhexyl) phthalate exposure and lipid metabolism in adolescents: Human data and experimental rat model analyses.
Environmental pollution (Barking, Essex : 1987)
Ding S,Qi W,Xu Q,Zhao T,Li X,Yin J,Zhang R,Huo C,Zhou L,Ye L
Fri Oct 01 00:00:00 EDT 2021
Intracellular AIBP (Apolipoprotein A-I Binding Protein) Regulates Oxidized LDL (Low-Density Lipoprotein)-Induced Mitophagy in Macrophages.
Arteriosclerosis, thrombosis, and vascular biology
Choi SH,Agatisa-Boyle C,Gonen A,Kim A,Kim J,Alekseeva E,Tsimikas S,Miller YI
Mon Feb 01 00:00:00 EST 2021
Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer.
Cell death discovery
Xu H,Xia H,Zhou S,Tang Q,Bi F
Fri Feb 26 00:00:00 EST 2021
A critical role for MSR1 in vesicular stomatitis virus infection of the central nervous system.
iScience
Yang D,Lin T,Li C,Harrison AG,Geng T,Wang P
Fri Jun 25 00:00:00 EDT 2021
Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF‑κB signaling.
Molecular medicine reports
Ma B,Wang X,Zhang R,Niu S,Rong Z,Ni L,Di X,Han Q,Liu C
Sat May 01 00:00:00 EDT 2021
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Metabolites
Zhao Y,He L,Wang T,Zhu L,Yan N
Mon Aug 23 00:00:00 EDT 2021
MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice.
Metabolism: clinical and experimental
Xu X,Dong Y,Ma N,Kong W,Yu C,Gong L,Chen J,Ren J
Tue Jun 01 00:00:00 EDT 2021
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Nature communications
Zhu Y,Feng F,Hu G,Wang Y,Yu Y,Zhu Y,Xu W,Cai X,Sun Z,Han W,Ye R,Qu D,Ding Q,Huang X,Chen H,Xu W,Xie Y,Cai Q,Yuan Z,Zhang R
Thu Feb 11 00:00:00 EST 2021
TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation.
Biochimica et biophysica acta. Molecular basis of disease
Sun Y,Ren D,Yang C,Yang W,Zhao J,Zhou Y,Jin X,Wu H
Mon Nov 01 00:00:00 EDT 2021
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
ACS chemical neuroscience
Guo X,Bao X,Wang X,Liu D,Liu P,Chi T,Ji X,Zheng Z,Chen G,Zou L
Wed Nov 03 00:00:00 EDT 2021
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Redox biology
Zhong S,Li L,Liang N,Zhang L,Xu X,Chen S,Yin H
Sat May 01 00:00:00 EDT 2021
Identification of a novel mechanism for meso-tetra (4-carboxyphenyl) porphyrin (TCPP) uptake in cancer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Elzi DJ,Bauta WE,Sanchez JR,Das T,Mogare S,Zannes Fatland P,Iza M,Pertsemlidis A,Rebel VI
Mon Mar 01 00:00:00 EST 2021
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Frontiers in cardiovascular medicine
Zhang XM,Gu YH,Deng H,Xu ZQ,Zhong ZY,Lyu XJ,Jin HM,Yang XH
Tue Jul 27 00:00:00 EDT 2021
Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells.
Nutrients
Huang Y,Tocmo R,Nauman MC,Haughan MA,Johnson JJ
Fri Sep 10 00:00:00 EDT 2021
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Frontiers in pharmacology
Chen K,Ma Z,Yan X,Liu J,Xu W,Li Y,Dai Y,Zhang Y,Xiao H
Thu Apr 14 00:00:00 EDT 2022
A Protein Corona Adsorbed to a Bacterial Magnetosome Affects Its Cellular Uptake.
International journal of nanomedicine
Lai W,Li D,Wang Q,Nan X,Xiang Z,Ma Y,Liu Y,Chen J,Tian J,Fang Q
Tue May 26 00:00:00 EDT 2020
Overexpression of close homolog of L1 enhances the chemosensitivity of lung cancer cells via inhibition of the Akt pathway.
Oncology letters
Cai X,Hu B,Liu S,Liu M,Huang Y,Lei P,Zhang Z,He Z,Zhang L,Huang R
Thu Oct 01 00:00:00 EDT 2020
Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression.
The Journal of biological chemistry
Wang D,Yang X,Chen Y,Gong K,Yu M,Gao Y,Wu X,Hu H,Liao C,Han J,Duan Y
Fri Nov 20 00:00:00 EST 2020
Dietary Betaine Addition Promotes Hepatic Cholesterol Synthesis, Bile Acid Conversion, and Export in Rats.
Nutrients
Li S,Xu S,Zhao Y,Wang H,Feng J
Wed May 13 00:00:00 EDT 2020
MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor.
PloS one
Wang N,He L,Lin H,Tan L,Sun Y,Zhang X,Danser AHJ,Lu HS,He Y,Lu X
Wed Sep 09 00:00:00 EDT 2020
Hydrogen sulfide accumulates LDL receptor precursor via downregulating PCSK9 in HepG2 cells.
American journal of physiology. Cell physiology
Huang Y,Ning K,Li WW,Lin G,Hou CL,Wang MJ,Zhu YC
Tue Dec 01 00:00:00 EST 2020
Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.
Cell metabolism
Fu Y,Sun Y,Wang M,Hou Y,Huang W,Zhou D,Wang Z,Yang S,Tang W,Zhen J,Li Y,Wang X,Liu M,Zhang Y,Wang B,Liu G,Yu X,Sun J,Zhang C,Yi F
Tue Dec 01 00:00:00 EST 2020
Cigarette smoke exposure impairs lipid metabolism by decreasing low-density lipoprotein receptor expression in hepatocytes.
Lipids in health and disease
Ma B,Chen Y,Wang X,Zhang R,Niu S,Ni L,Di X,Han Q,Liu C
Fri May 08 00:00:00 EDT 2020
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
The Journal of clinical investigation
Zhong S,Li L,Zhang YL,Zhang L,Lu J,Guo S,Liang N,Ge J,Zhu M,Tao Y,Wu YC,Yin H
Wed Jan 02 00:00:00 EST 2019
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
The Journal of clinical investigation
Zhong S,Li L,Zhang YL,Zhang L,Lu J,Guo S,Liang N,Ge J,Zhu M,Tao Y,Wu YC,Yin H
Wed Jan 02 00:00:00 EST 2019
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
The Journal of clinical investigation
Zhong S,Li L,Zhang YL,Zhang L,Lu J,Guo S,Liang N,Ge J,Zhu M,Tao Y,Wu YC,Yin H
Wed Jan 02 00:00:00 EST 2019
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
The Journal of clinical investigation
Zhong S,Li L,Zhang YL,Zhang L,Lu J,Guo S,Liang N,Ge J,Zhu M,Tao Y,Wu YC,Yin H
Wed Jan 02 00:00:00 EST 2019
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Journal of cellular biochemistry
Cao S,Xu P,Yan J,Liu H,Liu L,Cheng L,Qiu F,Kang N
Fri Feb 01 00:00:00 EST 2019
Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells.
Journal of cellular biochemistry
Cao S,Xu P,Yan J,Liu H,Liu L,Cheng L,Qiu F,Kang N
Fri Feb 01 00:00:00 EST 2019
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
Nature communications
Guo HH,Feng CL,Zhang WX,Luo ZG,Zhang HJ,Zhang TT,Ma C,Zhan Y,Li R,Wu S,Abliz Z,Li C,Li XL,Ma XL,Wang LL,Zheng WS,Han YX,Jiang JD
Tue Apr 30 00:00:00 EDT 2019
Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages.
Redox biology
Guo S,Lu J,Zhuo Y,Xiao M,Xue X,Zhong S,Shen X,Yin C,Li L,Chen Q,Zhu M,Chen B,Zhao M,Zheng L,Tao Y,Yin H
Fri Feb 01 00:00:00 EST 2019
Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages.
Redox biology
Guo S,Lu J,Zhuo Y,Xiao M,Xue X,Zhong S,Shen X,Yin C,Li L,Chen Q,Zhu M,Chen B,Zhao M,Zheng L,Tao Y,Yin H
Fri Feb 01 00:00:00 EST 2019
Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages.
Redox biology
Guo S,Lu J,Zhuo Y,Xiao M,Xue X,Zhong S,Shen X,Yin C,Li L,Chen Q,Zhu M,Chen B,Zhao M,Zheng L,Tao Y,Yin H
Fri Feb 01 00:00:00 EST 2019
Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells.
Scientific reports
Zhu L,Wu G,Yang X,Jia X,Li J,Bai X,Li W,Zhao Y,Li Y,Cheng W,Liu S,Jin S
Thu Feb 28 00:00:00 EST 2019
Therapeutic Effect of Chitooligosaccharide Tablets on Lipids in High-Fat Diets Induced Hyperlipidemic Rats.
Molecules (Basel, Switzerland)
Yang D,Hu C,Deng X,Bai Y,Cao H,Guo J,Su Z
Thu Jan 31 00:00:00 EST 2019
Lead exposure induces Alzheimers's disease (AD)-like pathology and disturbes cholesterol metabolism in the young rat brain.
Toxicology letters
Zhou CC,Gao ZY,Wang J,Wu MQ,Hu S,Chen F,Liu JX,Pan H,Yan CH
Mon Oct 15 00:00:00 EDT 2018
Lead exposure induces Alzheimers's disease (AD)-like pathology and disturbes cholesterol metabolism in the young rat brain.
Toxicology letters
Zhou CC,Gao ZY,Wang J,Wu MQ,Hu S,Chen F,Liu JX,Pan H,Yan CH
Mon Oct 15 00:00:00 EDT 2018
Lead exposure induces Alzheimers's disease (AD)-like pathology and disturbes cholesterol metabolism in the young rat brain.
Toxicology letters
Zhou CC,Gao ZY,Wang J,Wu MQ,Hu S,Chen F,Liu JX,Pan H,Yan CH
Mon Oct 15 00:00:00 EDT 2018
Lead exposure induces Alzheimers's disease (AD)-like pathology and disturbes cholesterol metabolism in the young rat brain.
Toxicology letters
Zhou CC,Gao ZY,Wang J,Wu MQ,Hu S,Chen F,Liu JX,Pan H,Yan CH
Mon Oct 15 00:00:00 EDT 2018
A Novel Role of Id1 in Regulating Oscillatory Shear Stress-Mediated Lipid Uptake in Endothelial Cells.
Annals of biomedical engineering
Zhang K,Chen Y,Zhang T,Huang L,Wang Y,Yin T,Qiu J,Gregersen H,Wang G
Fri Jun 01 00:00:00 EDT 2018
A Novel Role of Id1 in Regulating Oscillatory Shear Stress-Mediated Lipid Uptake in Endothelial Cells.
Annals of biomedical engineering
Zhang K,Chen Y,Zhang T,Huang L,Wang Y,Yin T,Qiu J,Gregersen H,Wang G
Fri Jun 01 00:00:00 EDT 2018
A Novel Role of Id1 in Regulating Oscillatory Shear Stress-Mediated Lipid Uptake in Endothelial Cells.
Annals of biomedical engineering
Zhang K,Chen Y,Zhang T,Huang L,Wang Y,Yin T,Qiu J,Gregersen H,Wang G
Fri Jun 01 00:00:00 EDT 2018
A Novel Role of Id1 in Regulating Oscillatory Shear Stress-Mediated Lipid Uptake in Endothelial Cells.
Annals of biomedical engineering
Zhang K,Chen Y,Zhang T,Huang L,Wang Y,Yin T,Qiu J,Gregersen H,Wang G
Fri Jun 01 00:00:00 EDT 2018
Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Idriss AA,Hu Y,Hou Z,Hu Y,Sun Q,Omer NA,Abobaker H,Ni Y,Zhao R
Thu Mar 01 00:00:00 EST 2018
Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Idriss AA,Hu Y,Hou Z,Hu Y,Sun Q,Omer NA,Abobaker H,Ni Y,Zhao R
Thu Mar 01 00:00:00 EST 2018
Polydatin Improves Glucose and Lipid Metabolisms in Insulin-Resistant HepG2 Cells through the AMPK Pathway.
Biological & pharmaceutical bulletin
Hao J,Huang K,Chen C,Liang Y,Wang Y,Zhang X,Huang H
Thu Oct 04 00:00:00 EDT 2018
Polydatin Improves Glucose and Lipid Metabolisms in Insulin-Resistant HepG2 Cells through the AMPK Pathway.
Biological & pharmaceutical bulletin
Hao J,Huang K,Chen C,Liang Y,Wang Y,Zhang X,Huang H
Thu Oct 04 00:00:00 EDT 2018
Cholesterol-lowering effects and potential mechanisms of chitooligosaccharide capsules in hyperlipidemic rats.
Food & nutrition research
Jiang Y,Fu C,Liu G,Guo J,Su Z
Fri Mar 18 00:00:00 EDT 2022
Cholesterol-lowering effects and potential mechanisms of chitooligosaccharide capsules in hyperlipidemic rats.
Food & nutrition research
Jiang Y,Fu C,Liu G,Guo J,Su Z
Fri Mar 18 00:00:00 EDT 2022
In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.
Arteriosclerosis, thrombosis, and vascular biology
Chadwick AC,Wang X,Musunuru K
Fri Sep 01 00:00:00 EDT 2017
In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.
Arteriosclerosis, thrombosis, and vascular biology
Chadwick AC,Wang X,Musunuru K
Fri Sep 01 00:00:00 EDT 2017
Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.
International journal of molecular medicine
Bian F,Cui J,Zheng T,Jin S
Wed Mar 01 00:00:00 EST 2017
Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.
International journal of molecular medicine
Bian F,Cui J,Zheng T,Jin S
Wed Mar 01 00:00:00 EST 2017
Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop.
Oncotarget
Bai XL,Yang XY,Li JY,Jia X,Xiong ZF,Wang YM,Jin S
Tue Nov 28 00:00:00 EST 2017
Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop.
Oncotarget
Bai XL,Yang XY,Li JY,Jia X,Xiong ZF,Wang YM,Jin S
Tue Nov 28 00:00:00 EST 2017
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Journal of virology
Yang Z,Wang X,Chi X,Zhao F,Guo J,Ma P,Zhong J,Niu J,Pan X,Long G
Tue Nov 01 00:00:00 EDT 2016
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Journal of virology
Yang Z,Wang X,Chi X,Zhao F,Guo J,Ma P,Zhong J,Niu J,Pan X,Long G
Tue Nov 01 00:00:00 EDT 2016
Hypolipidemic effects of Myrica rubra extracts and main compounds in C57BL/6j mice.
Food & function
He K,Li X,Xiao Y,Yong Y,Zhang Z,Li S,Zhou T,Yang D,Gao P,Xin X
Wed Aug 10 00:00:00 EDT 2016
Hypolipidemic effects of Myrica rubra extracts and main compounds in C57BL/6j mice.
Food & function
He K,Li X,Xiao Y,Yong Y,Zhang Z,Li S,Zhou T,Yang D,Gao P,Xin X
Wed Aug 10 00:00:00 EDT 2016
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Journal of agricultural and food chemistry
Jia Y,Ling M,Zhang L,Jiang S,Sha Y,Zhao R
Wed Oct 12 00:00:00 EDT 2016
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Journal of agricultural and food chemistry
Jia Y,Ling M,Zhang L,Jiang S,Sha Y,Zhao R
Wed Oct 12 00:00:00 EDT 2016
Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
Biochemical and biophysical research communications
Liu M,Zhang W,Li X,Han J,Chen Y,Duan Y
Fri Jan 15 00:00:00 EST 2016
Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
Biochemical and biophysical research communications
Liu M,Zhang W,Li X,Han J,Chen Y,Duan Y
Fri Jan 15 00:00:00 EST 2016
The antihypercholesterolemic effect of columbamine from Rhizoma Coptidis in HFHC-diet induced hamsters through HNF-4α/FTF-mediated CYP7A1 activation.
Fitoterapia
Wang Y,Han Y,Chai F,Xiang H,Huang T,Kou S,Han B,Gong X,Ye X
Thu Dec 01 00:00:00 EST 2016
The antihypercholesterolemic effect of columbamine from Rhizoma Coptidis in HFHC-diet induced hamsters through HNF-4α/FTF-mediated CYP7A1 activation.
Fitoterapia
Wang Y,Han Y,Chai F,Xiang H,Huang T,Kou S,Han B,Gong X,Ye X
Thu Dec 01 00:00:00 EST 2016
Exogenous administration of chronic corticosterone affects hepatic cholesterol metabolism in broiler chickens showing long or short tonic immobility.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
Liu J,Duan Y,Hu Y,Sun L,Wang S,Fu W,Ni Y,Zhao R
Fri Jan 01 00:00:00 EST 2016
Exogenous administration of chronic corticosterone affects hepatic cholesterol metabolism in broiler chickens showing long or short tonic immobility.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
Liu J,Duan Y,Hu Y,Sun L,Wang S,Fu W,Ni Y,Zhao R
Fri Jan 01 00:00:00 EST 2016
Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism.
Oncotarget
Sun L,Dong H,Zhang Z,Liu J,Hu Y,Ni Y,Grossmann R,Zhao R
Tue May 10 00:00:00 EDT 2016
Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism.
Oncotarget
Sun L,Dong H,Zhang Z,Liu J,Hu Y,Ni Y,Grossmann R,Zhao R
Tue May 10 00:00:00 EDT 2016
Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats.
Lipids in health and disease
Zhou J,Gao S,Chen J,Zhao R,Yang X
Fri Jul 22 00:00:00 EDT 2016
Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats.
Lipids in health and disease
Zhou J,Gao S,Chen J,Zhao R,Yang X
Fri Jul 22 00:00:00 EDT 2016
Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways.
Biochimica et biophysica acta
He K,Hu Y,Ma H,Zou Z,Xiao Y,Yang Y,Feng M,Li X,Ye X
Thu Sep 01 00:00:00 EDT 2016
Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways.
Biochimica et biophysica acta
He K,Hu Y,Ma H,Zou Z,Xiao Y,Yang Y,Feng M,Li X,Ye X
Thu Sep 01 00:00:00 EDT 2016
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Nutrients
Cai D,Yuan M,Liu H,Pan S,Ma W,Hong J,Zhao R
Tue Oct 18 00:00:00 EDT 2016
The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters.
Lipids
He K,Ye X,Wu H,Wang Y,Zou Z,Ning N,Hu Y,Chen B,Fang X,Li X
Sun Feb 01 00:00:00 EST 2015
The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters.
Lipids
He K,Ye X,Wu H,Wang Y,Zou Z,Ning N,Hu Y,Chen B,Fang X,Li X
Sun Feb 01 00:00:00 EST 2015
TATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine.
Scientific reports
Yuan ZY,Lu X,Lei F,Chai YS,Wang YG,Jiang JF,Feng TS,Wang XP,Yu X,Yan XJ,Xing DM,Du LJ
Wed Dec 16 00:00:00 EST 2015
TATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine.
Scientific reports
Yuan ZY,Lu X,Lei F,Chai YS,Wang YG,Jiang JF,Feng TS,Wang XP,Yu X,Yan XJ,Xing DM,Du LJ
Wed Dec 16 00:00:00 EST 2015
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Journal of molecular and cellular cardiology
Zhang Y,Yang X,Bian F,Wu P,Xing S,Xu G,Li W,Chi J,Ouyang C,Zheng T,Wu D,Zhang Y,Li Y,Jin S
Tue Jul 01 00:00:00 EDT 2014
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Journal of molecular and cellular cardiology
Zhang Y,Yang X,Bian F,Wu P,Xing S,Xu G,Li W,Chi J,Ouyang C,Zheng T,Wu D,Zhang Y,Li Y,Jin S
Tue Jul 01 00:00:00 EDT 2014
Danhong injection inhibits the development of atherosclerosis in both Apoe⁻/⁻ and Ldlr⁻/⁻ mice.
Journal of cardiovascular pharmacology
Chen Y,Liu M,Zhao T,Zhao B,Jia L,Zhu Y,Zhang B,Gao X,Li G,Li X,Xiang R,Han J,Duan Y
Thu May 01 00:00:00 EDT 2014
Danhong injection inhibits the development of atherosclerosis in both Apoe⁻/⁻ and Ldlr⁻/⁻ mice.
Journal of cardiovascular pharmacology
Chen Y,Liu M,Zhao T,Zhao B,Jia L,Zhu Y,Zhang B,Gao X,Li G,Li X,Xiang R,Han J,Duan Y
Thu May 01 00:00:00 EDT 2014
Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
Duan Y,Fu W,Wang S,Ni Y,Zhao R
Wed Oct 01 00:00:00 EDT 2014
Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
Duan Y,Fu W,Wang S,Ni Y,Zhao R
Wed Oct 01 00:00:00 EDT 2014
