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LGR7 Antibody (PA5-28759) in WB
Western Blot using LGR7 Polyclonal Antibody (Product # PA5-28759). Sample (30 µg of whole cell lysate). A: 293T. B: H1299. 7.5% SDS PAGE. LGR7 Polyclonal Antibody (Product # PA5-28759) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-28759
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 693 and 757 of Human GPCR LGR7
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546235
Product Specific Information
Recommended positive controls: 293T, H1299.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
LGR7 is a low density lipoprotein receptor of 757amino acid belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity. It has seven transmembrane region, cysteine-rich motif, 10 LRR domains and 5 N-glycosylation sites in the N terminus. Research reports show that it has receptor for relaxins (RLN1 and RLN2) which stimulates adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes. LGR7 is critical for mediating these biological responses by use of RNA interference lentiviral short hairpin constructs. It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis and endometrium.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: leucine-rich repeat-containing G protein-coupled receptor 7; Leucine-rich repeat-containing G-protein coupled receptor 7; LGR7.1; LGR7.10; LGR7.2; MGC138347; MGC142177; Relaxin family peptide receptor 1; Relaxin receptor 1; relaxin/insulin-like family peptide receptor 1
Gene Aliases: LGR7; RXFP1; RXFPR1
UniProt ID: (Human) Q9HBX9
Entrez Gene ID: (Human) 59350
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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