Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
LHX3 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-40754
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human LHX3
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2576762
Product Specific Information
Peptide sequence: QNRRAKEKRL KKDAGRQRWG QYFRNMKRSR GGSKSDKDSV QEGQDSDAEV
Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 87%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 80%
Target Information
This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DKFZp762A2013; LIM homeobox protein 3; LIM/homeobox protein Lhx3; LIM/homeodomain protein LHX3
Gene Aliases: CPHD3; LHX3; LIM3; M2-LHX3
UniProt ID: (Human) Q9UBR4
Entrez Gene ID: (Human) 8022
transcription factor activity, RNA polymerase II transcription factor binding
RNA polymerase II transcription factor binding
zinc ion binding
sequence-specific DNA binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
placenta development
transcription, DNA-templated
motor neuron axon guidance
organ morphogenesis
spinal cord motor neuron cell fate specification
ventral spinal cord interneuron specification
medial motor column neuron differentiation
spinal cord association neuron differentiation
pituitary gland development
lung development
negative regulation of apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
inner ear development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support