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LIFR Antibody (PA5-115511) in IHC (P)
Immunohistochemistry analysis of LIFR in human normal tissues adjacent to pancreatic cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115511) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115511
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human LIFR(Accession P42702), corresponding to amino acid residues E319-Y369.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900147
Product Specific Information
Antibody detects endogenous levels of total LIFR.
Target Information
Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD118; CD118 antigen; D-factor/LIF receptor; FLJ98106; FLJ99923; leukemia inhibitor factor receptor alpha-chain; Leukemia inhibitory factor receptor; leukemia inhibitory factor receptor alpha chain; LIF R beta; LIF receptor; LIF-R; soluble differentiation-stimulating factor receptor
Gene Aliases: A230075M04Rik; AW061234; CD118; LIF; LIF-R; LIFR; SJS2; STWS; SWS
UniProt ID: (Human) P42702, (Rat) O70535, (Mouse) P42703
Entrez Gene ID: (Human) 3977, (Rat) 81680, (Mouse) 16880
ciliary neurotrophic factor receptor activity
leukemia inhibitory factor receptor activity
oncostatin-M receptor activity
ciliary neurotrophic factor receptor binding
protein binding
growth factor binding
cytokine binding
protein heterodimerization activity
cytokine receptor activity
transmembrane signal receptor
cell surface receptor signaling pathway
positive regulation of cell proliferation
negative regulation of muscle cell apoptotic process
response to organic cyclic compound
cytokine-mediated signaling pathway
organ regeneration
response to cytokine
oncostatin-M-mediated signaling pathway
neuron projection morphogenesis
leukemia inhibitory factor signaling pathway
ciliary neurotrophic factor-mediated signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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