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Product Details
MA5-31196
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
110
Immunogen
Recombinant Mouse LIFR protein (Met1-Ser828)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2786843
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse LIFR.
Target Information
Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD118; D-factor/LIF receptor; FLJ98106; FLJ99923; Leukemia inhibitory factor receptor; leukemia inhibitory factor receptor alpha chain; LIF R beta; LIF receptor; LIF-R; soluble differentiation-stimulating factor receptor
Gene Aliases: A230075M04Rik; AW061234; LIF; Lifr
UniProt ID: (Mouse) P42703
Entrez Gene ID: (Mouse) 16880
cytokine receptor activity
ciliary neurotrophic factor receptor activity
leukemia inhibitory factor receptor activity
oncostatin-M receptor activity
ciliary neurotrophic factor receptor binding
protein binding
growth factor binding
cytokine binding
protein heterodimerization activity
transmembrane signal receptor
positive regulation of cell proliferation
negative regulation of muscle cell apoptotic process
cytokine-mediated signaling pathway
organ regeneration
response to cytokine
oncostatin-M-mediated signaling pathway
neuron projection morphogenesis
leukemia inhibitory factor signaling pathway
ciliary neurotrophic factor-mediated signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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