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LILRA3 Antibody (H00011026-D01P) in WB
Western Blot analysis of LILRA3 expression in transfected 293T cell line (H00011026-T02) by LILRA3 MaxPab polyclonal antibody.
Lane 1: LILRA3 transfected lysate(47.50 KDa).
Lane 2: Non-transfected lysate.
Lane 1: LILRA3 transfected lysate(47.50 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00011026-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LILRA3 (NP_006856.2, 1 a.a. approximately 439 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MTSILTVLIC LGLSLDPRTH VQAGPLPKPT LWAEPGSVIT QGSPVTLRCQ GSLETQEYHL YREKKTALWI TRIPQELVKK GQFPILSITW EHAGRYCCIY GSHTVGLSES SDPLELVVTG AYSKPTLSAL PSPVVTSGGN VTIQCDSQVA FDGFILCKEG EDEHPQCLNS HSHARGSSRA IFSVGPVSPS RRWSYRCYGY DSRAPYVWSL PSDLLGLLVP GVSKKPSLSV QPGPVVAPGE KLTFQCGSDA GYDRFVLYKE WGRDFLQRPG RQPQAGLSQA NFTLGPVSRS YGGQYTCSGA YNLSSEWSAP SDPLDILITG QIRARPFLSV RPGPTVASGE NVTLLCQSQG GMHTFLLTKE GAADSPLRLK SKRQSHKYQA EFPMSPVTSA HAGTYRCYGS LSSNPYLLTH PSDPLELVVS GAAETLSPPQ NKSDSKAGE
Target Information
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD85 antigen-like family member E; CD85e; ILT-6; Immunoglobulin-like transcript 6; leucocyte Ig-like receptor A3; Leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor A3; Leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; LIR-4; Monocyte inhibitory receptor HM43/HM31
Gene Aliases: CD85E; HM31; HM43; ILT-6; ILT6; LILRA3; LIR-4; LIR4
UniProt ID: (Human) Q8N6C8
Entrez Gene ID: (Human) 11026
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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