Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRKDTDDIES PKRSIRDSGY IDCWDSERSD SLSPPRHGRD DSFDSLDSFG SRSRQTPSPD VVLRGSSDGR GSDSESDLPH RKLPDVKKDD MSARRTSHGE PKSAVPFNQY LPNKSNQTAY VPAPLRKKKA EREEYRKSWS TATSPLGGER PFRYGPRTPV SDDAESTSMF DMRCEEEAAV QPHSRARQEQ LQLINNQLRE EDDKWQDDLA RWKSRRRSVS QDLIKKEEER KKMEKLLAGE DGTSERRKSI KTYREIVQEK ERRERELHEA YKNARSQEEA EGILQQYIER FTISEAVLER LEMPKILERS HSTEPNLSSF LNDPNPMKYL RQQSLPPPKF TATVETTIAR ASVLDTSMSA GSGSPSKTVT PKAVPMLTPK PYSQPKNSQD VLKTFKVDGK VSVNGETVHR EEEKERECPT VAPAHSLTKS QMFEGVARVH GSPLELKQDN GSIEINIKKP NSVPQELAAT TEKTEPNSQE DKNDGGKSRK GNIELASSEP QHFTTTVTRC SPTVAFVEFP SSPQLKNDVS EEKDQKKPEN EMSGKVELVL SQKVVKPKSP EPEATLTFPF LDKMPEANQL HLPNLNSQVD SPSSEKSPVT TPFKFWAWDP EEERRRQEKW QQEQERLLQE RYQKEQDKLK EEWEKAQKEV EEEERRYYEE ERKIIEDTVV PFTVSSSSAD QLSTSSSMTE GSGTMNKIDL GNCQDEKQDR RWKKSFQGDD SDLLLKTRES DRLEEKGSLT EGALAHSGNP VSKGVHEDHQ LDTEAGAPHC GTNPQLAQDP SQNQQTSNPT HSSEDVKPKT LPLDKSINHQ IESPSERRKS ISGKKLCSSC GLPLGKGAAM IIETLNLYFH IQCFRCGICK GQLGDAVSGT DVRIRNGLLN CNDCYMRSRS AGQPTTL
Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LIM and calponin homology domains-containing protein 1
Gene Aliases: KIAA1102; LIMCH1; LIMCH1A; LMO7B
UniProt ID: (Human) Q9UPQ0
Entrez Gene ID: (Human) 22998
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