Proteintech

LIPE Polyclonal Antibody

LIPE Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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LIPE Antibody (17333-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 17333-1-AP (LIPE antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Product Details

17333-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 11 publications 11 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Pig

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LIPE Fusion Protein Ag11360

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

433 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

Hormone-sensitive lipase (HSL) is an intracellular neutral lipase found in a variety of tissues, but primarily in adipose and steroidogenic tissues. It hydrolyzes triglycerides and cholesteryl esters. It is the major enzyme responsible for the mobilization of free fatty acids from adopise tissue.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability.

Journal of experimental & clinical cancer research : CR

Chen X,Yong H,Chen M,Deng C,Wang P,Chu S,Li M,Hou P,Zheng J,Li Z,Bai J

Wed Jan 25 00:00:00 EST 2023

Identification of Adipogenesis Subgroups and Immune Infiltration Characteristics in Diabetic Peripheral Neuropathy.

Journal of immunology research

Lin Y,Qu L,Wu J,Pu M,Huang Y,Cao Y

Wed Feb 08 00:00:00 EST 2023

LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis.

International journal of biological sciences

Fang Y,Dou R,Huang S,Han L,Fu H,Yang C,Song J,Zheng J,Zhang X,Liu K,Xiang Z,Zhang X,Wang S,Xiong B

Thu May 12 00:00:00 EDT 2022

Human gingival mesenchymal stem cells improve movement disorders and tyrosine hydroxylase neuronal damage in Parkinson disease rats.

Cytotherapy

Lei T,Xiao Z,Zhang X,Cai S,Bi W,Yang Y,Wang D,Li Q,Du H

Tue Nov 01 00:00:00 EDT 2022

DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Zhou H,Zhang J,Yan Z,Qu M,Zhang G,Han J,Wang F,Sun K,Wang L,Yang X

Tue Mar 01 00:00:00 EST 2022

DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Zhou H,Zhang J,Yan Z,Qu M,Zhang G,Han J,Wang F,Sun K,Wang L,Yang X

Tue Mar 01 00:00:00 EST 2022

DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Zhou H,Zhang J,Yan Z,Qu M,Zhang G,Han J,Wang F,Sun K,Wang L,Yang X

Tue Mar 01 00:00:00 EST 2022

Paternal cadmium exposure affects testosterone synthesis by reducing the testicular cholesterol pool in offspring mice.

Ecotoxicology and environmental safety

Zhou J,Zhang Y,Zeng L,Wang X,Mu H,Wang M,Pan H,Su P

Thu Sep 01 00:00:00 EDT 2022

Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.

Life sciences

Liu J,Li D,Dun Y,Li H,Ripley-Gonzalez JW,Zhang J,Qiu L,You B,Liu S

Tue Nov 01 00:00:00 EDT 2022

Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.

Antioxidants (Basel, Switzerland)

Li DM,Wu YX,Hu ZQ,Wang TC,Zhang LL,Zhou Y,Tong X,Xu JY,Qin LQ

Sun Jul 31 00:00:00 EDT 2022

Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging.

Experimental animals

Iizuka Y,Kim H,Nakasatomi M,Matsumoto A,Shimizu J

Wed Feb 09 00:00:00 EST 2022

PLK1 promotes cholesterol efflux and alleviates atherosclerosis by up-regulating ABCA1 and ABCG1 expression via the AMPK/PPARγ/LXRα pathway.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Hu HJ,Wang XH,Zhang TQ,Liu Y,Chen ZR,Zhang ZZ,Huang H,Tang HF,Jiang ZS

Thu Dec 01 00:00:00 EST 2022

Differential regulatory roles of microRNAs during intramuscular adipogenesis in Chinese Guizhou Congjiang Xiang pigs.

Epigenetics

Tan L,Chen Z,Ruan Y,Xu H

Thu Dec 01 00:00:00 EST 2022

CircRNA-mediated regulation of brown adipose tissue adipogenesis.

Frontiers in nutrition

Liu K,Liu X,Deng Y,Li Z,Tang A

Tue Aug 16 00:00:00 EDT 2022

Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.

Food & function

Han X,Guo J,Gao Y,Zhan J,You Y,Huang W

Mon Feb 15 00:00:00 EST 2021

Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer.

Oncology reports

Cai Z,Liang Y,Xing C,Wang H,Hu P,Li J,Huang H,Wang W,Jiang C

Sun Dec 01 00:00:00 EST 2019

Bioinformatics

Protein Aliases: EC 3.1.1.79; Hormone-sensitive lipase; hormone-sensitive lipase testicular isoform; HSL; HSL antibody; lipase, hormone-sensitive; LIPS; Monoacylglycerol lipase LIPE; REH; Retinyl ester hydrolase

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Gene Aliases: 4933403G17Rik; AOMS4; FPLD6; HSL; LHS; LIPE; REH

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UniProt ID: (Human) Q05469, (Pig) Q68J42, (Mouse) P54310

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Entrez Gene ID: (Human) 3991, (Pig) 397583, (Mouse) 16890

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Function(s)

triglyceride lipase activity protein binding protein kinase binding hormone-sensitive lipase activity sterol esterase activity rRNA primary transcript binding acylglycerol lipase activity retinyl-palmitate esterase activity 1,3-diacylglycerol acylhydrolase activity 1,2-diacylglycerol acylhydrolase activity lipase activity hydrolase activity hydrolase activity, acting on ester bonds lipase hydrolase metabolite interconversion enzyme

Process(es)

protein phosphorylation cholesterol metabolic process lipid catabolic process triglyceride catabolic process long-chain fatty acid catabolic process diacylglycerol catabolic process transcription initiation from RNA polymerase I promoter termination of RNA polymerase I transcription retinol metabolic process ether lipid metabolic process lipid metabolic process metabolic process steroid metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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LIPE Polyclonal Antibody

LIPE Antibody (17333-1-AP) in IHC (P)

Product Details

17333-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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