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LOX 1 Antibody (BS-2044R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with LOX 1 Polyclonal Antibody, Unconjugated (bs-2044R) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DA... View More
Product Details
BS-2044R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from Rabbit LOX-1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-type lectin domain family 8 member A; hLOX 1; hLOX-1; hLOX1; Lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1; LOX 1; LOX-1; ox LDL receptor 1; Ox-LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; Oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; scavenger receptor class E, member 1; sLOX 1; soluble LOX 1
Gene Aliases: CLEC8A; LOX-1; LOX1; LOXIN; Oldlr1; Oldr1; OLR1; SCARE1; SLOX1; SR-EI
UniProt ID: (Human) P78380, (Rabbit) Q9XTA8, (Mouse) Q9EQ09, (Rat) O70156
Entrez Gene ID: (Human) 4973, (Rabbit) 100009322, (Mouse) 108078, (Rat) 140914
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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