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LOX-1 Antibody (PA5-88326) in WB
Western blot analysis of LOX-1 in extracts of Mouse lung. Samples were incubated with LOX-1 Polyclonal antibody (Product # PA5-88326) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-88326
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OLR1 (NP_0025341)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804831
Product Specific Information
Immunogen sequence: MTFDDLKIQT VKDQPDEKSN GKKAKGLQFL YSPWWCLAAA TLGVLCLGLV VTIMVLGMQL SQVSDLLTQE QANLTHQKKK LEGQISARQQ AEEASQESEN; Positive Samples: Mouse lung; Cellular Location: Cell membrane, Lipid-anchor, Membrane raft, Single-pass type II membrane protein
Target Information
LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hLOX 1; hLOX1; Lectin-like oxidized LDL receptor 1; lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1; LOX 1; LOX-1; Ox-LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; Oxidized low-density lipoprotein receptor 1; sLOX 1; soluble LOX 1
Gene Aliases: LOX-1; Lox1; Olr1; Scare1; SR-EI
UniProt ID: (Mouse) Q9EQ09
Entrez Gene ID: (Mouse) 108078
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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