Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: TCDVGVSSDD DKGAQAARGS SNASLKEEEC KEPLLFHSGD HYPLSDGDWS PLETTYPQTA CPKSDSELEV KPAESLLRSE SHMEWTWGGF PESTKVSKRE RSDHHPRTAT ITPSENTHFR VIPSEDNLIS EVEKDASMED TVCTIVKPKP RALGTQMSDP TSVAELLEPP LESTQISSML DADHLPNAAL AEAPSESKPA AKVDSPSKKK GVHKRSQHQG P; Positive Samples: LO2, 293T, A-549, DU145, Mouse liver, Mouse lung, Mouse kidney, Mouse spleen; Cellular Location: Cytoplasm, Endoplasmic reticulum membrane, Nucleus, cytosol
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lipin-2; Phosphatidate phosphatase LPIN2
Gene Aliases: 2610511G02Rik; AI481352; AW742896; KIAA0249; LPIN2
UniProt ID: (Human) Q92539, (Mouse) Q99PI5
Entrez Gene ID: (Human) 9663, (Mouse) 64898
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