Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Leupaxin
Gene Aliases: 4933402K05Rik; A530083L21Rik; AV278559; LDLP; LDPL; LPXN
UniProt ID: (Human) O60711, (Mouse) Q99N69
Entrez Gene ID: (Human) 9404, (Mouse) 107321, (Rat) 293783
Molecular Function:
actin or actin-binding cytoskeletal protein
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