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This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.
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Protein Aliases: 130 kDa leucine-rich protein; GP130; leucine-rich pentatricopeptide repeat containing; Leucine-rich PPR motif-containing protein, mitochondrial; leucine-rich PPR-motif containing; LRP 130; mitochondrial leucine-rich PPR motif-containing protein
Gene Aliases: CLONE-23970; GP130; LRP130; LRPPRC; LSFC
UniProt ID: (Human) P42704
Entrez Gene ID: (Human) 10128
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