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Invitrogen
LTBR Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 3
LTBR Antibody (PA5-88290) in WB
Western Blot was performed using Anti-LTBR Polyclonal Antibody (Product # PA5-88290) and a 55 kDa band corresponding to Tumor necrosis factor receptor superfamily member 3 was observed across the cell lines tested except in SH-SY5Y and HEK-293 which are reported to be negative. Whole cell extracts (30 µg lysate) of HeLa (Lane 1), A549 (Lane 2), MCF7 (Lane 3), HUVEC (Lane 4), SH-SY5Y (Lane 5) and HEK-293 (Lane 6) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0302BOX). Resolved proteins were then transferred onto a... View More
Product Details
PA5-88290
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 249-435 of human LTBR (NP_0023331)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804803
Product Specific Information
Immunogen sequence: KSHPSLCRKL GSLLKRRPQG EGPNPVAGSW EPPKAHPYFP DLVQPLLPIS GDVSPVSTGL PAAPVLEAGV PQQQSPLDLT REPQLEPGEQ SQVAHGTNGI HVTGGSMTIT GNIYIYNGPV LGGPPGPGDL PATPEPPYPI PEEGDPGPPG LSTPHQEDGK AWHLAETEHC GATPSNRGPR NQFITHD; Positive Samples: Mouse liver; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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