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LYPLA1 Polyclonal Antibody

LYPLA1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 15

LYPLA1 Antibody (16055-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 16055-1-AP (LYPLA1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

LYPLA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LYPLA1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

16055-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LYPLA1 Fusion Protein Ag9022 (1-230 aa encoded by BC010397)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MCGNNMSTP LPAIVPAARK ATAAVIFLHG LGDTGHGWAE AFAGIRSSHI KYICPHAPVR PVTLNMNVAM PSWFDIIGLS PDSQEDESGI KQAAENIKAL IDQEVKNGIP SNRIILGGFS QGGALSLYTA LTTQQKLAGV TALSCWLPLR ASFPQGPIGG ANRDISILQC HGDCDPLVPL MFGSLTVEKL KTLVNPANVT FKTYEGMMHS SCQQEMMDVK QFIDKLLPPI D (1-230 aa encoded by BC010397)

Target Information

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.

Autophagy

Liu Y,Zhang H,Liu Y,Zhang S,Su P,Wang L,Li Y,Liang Y,Wang X,Zhao W,Chen B,Luo D,Zhang N,Yang Q

Fri Sep 01 00:00:00 EDT 2023

PM_2.5 promoted lipid accumulation in macrophage via inhibiting JAK2/STAT3 signaling pathways and aggravating the inflammatory reaction.

Ecotoxicology and environmental safety

Yang L,Song Z,Pan Y,Zhao T,Shi Y,Xing J,Ju A,Zhou L,Ye L

Wed Dec 15 00:00:00 EST 2021

Development of an activity-based probe for acyl-protein thioesterases.

PloS one

Garland M,Schulze CJ,Foe IT,van der Linden WA,Child MA,Bogyo M

Wed Feb 21 00:00:00 EST 2018

Development of an activity-based probe for acyl-protein thioesterases.

PloS one

Garland M,Schulze CJ,Foe IT,van der Linden WA,Child MA,Bogyo M

Wed Feb 21 00:00:00 EST 2018

Identification of bioactivating enzymes involved in the hydrolysis of laninamivir octanoate, a long-acting neuraminidase inhibitor, in human pulmonary tissue.

Drug metabolism and disposition: the biological fate of chemicals

Koyama K,Ogura Y,Nakai D,Watanabe M,Munemasa T,Oofune Y,Kubota K,Shinagawa A,Izumi T

Sun Jun 01 00:00:00 EDT 2014

Identification of bioactivating enzymes involved in the hydrolysis of laninamivir octanoate, a long-acting neuraminidase inhibitor, in human pulmonary tissue.

Drug metabolism and disposition: the biological fate of chemicals

Koyama K,Ogura Y,Nakai D,Watanabe M,Munemasa T,Oofune Y,Kubota K,Shinagawa A,Izumi T

Sun Jun 01 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: Acyl-protein thioesterase 1; APT-1; LPL-I; lysophopholipase 1; Lysophospholipase 1; Lysophospholipase I; lysophospholipid-specific lysophospholipase; LYSOPLA; lysoPLA I; Palmitoyl-protein hydrolase; phospholipase 1a

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Gene Aliases: 25KDL; APT-1; APT1; hAPT1; LPL-I; LPL1; LYPLA1; Pla1a

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UniProt ID: (Human) O75608, (Rat) P70470, (Mouse) P97823

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Entrez Gene ID: (Human) 10434, (Rat) 25514, (Mouse) 18777

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Function(s)

lysophospholipase activity palmitoyl-(protein) hydrolase activity lipase activity CoA hydrolase activity hydrolase activity 2-oxoglutaryl-CoA thioesterase activity 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity 3-isopropylbut-3-enoyl-CoA thioesterase activity glutaryl-CoA hydrolase activity acyl-CoA hydrolase activity phospholipase

Process(es)

protein depalmitoylation fatty acid metabolic process negative regulation of Golgi to plasma membrane protein transport regulation of nitric-oxide synthase activity macromolecule depalmitoylation lipid metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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LYPLA1 Polyclonal Antibody

LYPLA1 Antibody (16055-1-AP) in ICC/IF

Product Details

16055-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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