Product References
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins.
Journal of medical virology
Zhang S,Ming SL,Zeng L,Wang LF,Zhang C,Zhu HS,Yang GY,Zhang GP,Chu BB,Wang J
Wed Mar 01 00:00:00 EST 2023
BMAL1 Promotes Valvular Interstitial Cells' Osteogenic Differentiation through NF-κ B/AKT/MAPK Pathway.
Journal of cardiovascular development and disease
Jiang Y,Wang S,Lin W,Gu J,Li G,Shao Y
Mon Mar 06 00:00:00 EST 2023
Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.
BMC complementary medicine and therapies
Cui Y,Zhang F,Xu W,Li Z,Zou J,Gao P,Hu J
Fri Jun 02 00:00:00 EDT 2023
DNA topoisomerase 2-associated proteins PATL1 and PATL2 regulate the biogenesis of hERG K+ channels.
Proceedings of the National Academy of Sciences of the United States of America
Yao L,Ruan MY,Ye SW,Cai SQ
Tue Jan 10 00:00:00 EST 2023
Novel Missense Variants in PAX8 and NKX2-1 Cause Congenital Hypothyroidism.
International journal of molecular sciences
Li M,Li Z,Chen M,Hu Z,Zhou M,Wu L,Zhang C,Liang D
Mon Jan 02 00:00:00 EST 2023
Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing.
Nature cell biology
Yan G,Yang J,Li W,Guo A,Guan J,Liu Y
Mon May 01 00:00:00 EDT 2023
Periplocin targets low density lipoprotein receptor-related protein 4 to attenuate osteoclastogenesis and protect against osteoporosis.
Biochemical pharmacology
Zhang X,Sun Z,Zhang Y,Pan L,Jiang W,Dong H,Jin Z,Kang J,Liu R,Ning B
Mon May 01 00:00:00 EDT 2023
PARP1 promotes NLRP3 activation via blocking TFEB-mediated autophagy in rotenone-induced neurodegeneration.
Ecotoxicology and environmental safety
Zhang H,Xie Z,Peng Y,Xie A,Fu C,Zheng D,Cai Z,Zhong J,Ming Q,Li M,Lu R,Liu X,Chen J
Wed Mar 01 00:00:00 EST 2023
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang C,Lu T,Liu M,Yuan X,Li D,Zhang J,Zhou L,Xu M
Wed Mar 01 00:00:00 EST 2023
NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia.
Oncology reports
Wang X,Rong S,Sun Y,Yin B,Yang X,Lu X,Sun H,Yan Y,Sun G,Liang Y,Wang P,Xie S,Li Y
Tue Aug 01 00:00:00 EDT 2023
Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity.
Cancer cell
Yan C,Zheng L,Jiang S,Yang H,Guo J,Jiang LY,Li T,Zhang H,Bai Y,Lou Y,Zhang Q,Liang T,Schamel W,Wang H,Yang W,Wang G,Zhu ZJ,Song BL,Xu C
Mon Jul 10 00:00:00 EDT 2023
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis.
Biochemical pharmacology
Mo X,Shen X,Mo X,Yu F,Tan W,Deng Z,He J,Luo Z,Chen Z,Yang J
Wed Mar 01 00:00:00 EST 2023
VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang W,Zuo J,Liu M,Su Y,Guo B,Hou J,Xing Q,Peng Y,Fang L,Cao Y,Shan J,Sun R,Zhao J,Wang J
Sun Jan 01 00:00:00 EST 2023
β-Hydroxybutyric acid upregulated by Suhuang antitussive capsule ameliorates cough variant asthma through GSK3β/AMPK-Nrf2 signal axis.
Journal of ethnopharmacology
Jiang H,Bai Z,Ou Y,Liu H,Si Z,Liu Y,Liu X,Liu X,Zhang Z,Tan N
Wed May 10 00:00:00 EDT 2023
Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways.
Biomolecules & biomedicine
Zhang H,Zeng J,Li J,Gong H,Chen M,Li Q,Liu S,Luo S,Dong H,Xu Y,Duan H,Haung L,Lv C
Mon May 01 00:00:00 EDT 2023
HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
Journal of virology
Ijezie EC,O'Dowd JM,Kuan MI,Faeth AR,Fortunato EA
Wed May 31 00:00:00 EDT 2023
Cytosolic Release of Mitochondrial DNA and Associated cGAS Signaling Mediates Radiation-Induced Hematopoietic Injury of Mice.
International journal of molecular sciences
Guan H,Zhang W,Xie D,Nie Y,Chen S,Sun X,Zhao H,Liu X,Wang H,Huang X,Bai C,Huang B,Zhou P,Gao S
Thu Feb 16 00:00:00 EST 2023
Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway.
Nutrients
Zhang Y,Zhu Z,Sun L,Yin W,Liang Y,Chen H,Bi Y,Zhai W,Yin Y,Zhang W
Tue Apr 11 00:00:00 EDT 2023
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4.
Reproductive sciences (Thousand Oaks, Calif.)
Liu W,Cheng L,Du Y,Liu X,Ma J,Yan L
Sun Oct 01 00:00:00 EDT 2023
DNAJB7 is dispensable for male fertility in mice.
Reproductive biology and endocrinology : RB&E
Bai S,Hu M,Yu L,Chen L,Zhou J,Wu L,Xu B,Jiang X,Zhang X,Tong X,Yue Q
Fri Mar 31 00:00:00 EDT 2023
Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt-GSK-3β-Nrf2 pathway.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Liu X,Liu Y,Chen L,Zhang Z,Cui L,Wei T
Wed Mar 01 00:00:00 EST 2023
LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway.
Molecular therapy. Nucleic acids
Xie R,Fan J,Wen J,Jin K,Zhan J,Yuan S,Tang Y,Nie X,Wen Z,Li H,Chen C,Wang DW
Tue Jun 13 00:00:00 EDT 2023
Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication.
Journal of ethnopharmacology
Zhao J,Xu G,Hou X,Mu W,Yang H,Shi W,Wen J,Liu T,Wu Z,Bai J,Zhang P,Wang Z,Xiao X,Zou W,Bai Z,Zhan X
Sat Jul 15 00:00:00 EDT 2023
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Clinical and experimental pharmacology & physiology
Wu H,Wu L,Xiao L,Gu Y,Liu H,Zhang L,Zhang M,Qi L
Sat Apr 01 00:00:00 EDT 2023
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Q,Liu S,Wang H,Xiao K,Lu J,Chen S,Huang M,Xie R,Lin T,Chen X
Sat Apr 01 00:00:00 EDT 2023
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Xia W,Xiao J,Tong C,Lu J,Tu Y,Li S,Ni L,Shi Y,Luo P,Zhang X,Wang X
Wed Nov 01 00:00:00 EDT 2023
Inhibition of the transcription factor ZNF281 by SUFU to suppress tumor cell migration.
Cell death and differentiation
Deng Y,Peng D,Xiao J,Zhao Y,Ding W,Yuan S,Sun L,Ding J,Zhou Z,Zhan M
Wed Mar 01 00:00:00 EST 2023
Polysaccharides extracted from mulberry fruits (Morus nigra L.): antioxidant effect of ameliorating H2O2-induced liver injury in HepG2 cells.
BMC complementary medicine and therapies
Li X,Hua Y,Yang C,Liu S,Tan L,Guo J,Li Y
Wed Apr 12 00:00:00 EDT 2023
METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing.
Journal of translational medicine
Wang X,Wang J,Zhao X,Wu H,Li J,Cheng Y,Guo Q,Cao X,Liang T,Sun L,Zhang G
Fri Jun 23 00:00:00 EDT 2023
METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing.
Journal of translational medicine
Wang X,Wang J,Zhao X,Wu H,Li J,Cheng Y,Guo Q,Cao X,Liang T,Sun L,Zhang G
Fri Jun 23 00:00:00 EDT 2023
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Autophagy
Wu H,Liu Q,Shan X,Gao W,Chen Q
Sat Jul 01 00:00:00 EDT 2023
Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines.
International journal of molecular sciences
Kanna M,Nakatsu Y,Yamamotoya T,Kushiyama A,Fujishiro M,Sakoda H,Ono H,Arihiro K,Asano T
Tue May 16 00:00:00 EDT 2023
A plant-derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy.
British journal of pharmacology
Wang Y,Gao J,Yu Y,Zhou L,Wang M,Xue W,Liu B,Wu X,Wu X,Gao H,Shen Y,Xu Q
Sun Jan 01 00:00:00 EST 2023
Histone methyltransferase Setdb1 mediates osteogenic differentiation by suppressing the expression of miR-212-3p under mechanical unloading.
Cellular signalling
Zhang L,Xu L,Wang Y,Zhang X,Xue T,Sun Q,Tang H,Li M,Cao X,Shi F,Zhang G,Zhang S,Hu Z
Wed Feb 01 00:00:00 EST 2023
Hepatic ZBTB22-mediated detoxification ameliorates acetaminophen-induced liver injury by inhibiting pregnane X receptor signaling.
iScience
Chen Y,Cui T,Xiao S,Li T,Zhong Y,Tang K,Guo J,Huang S,Chen J,Li J,Wang Q,Huang J,Pan H,Gao Y
Fri Apr 21 00:00:00 EDT 2023
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
The Journal of experimental medicine
Chu Q,An J,Liu P,Song Y,Zhai X,Yang R,Niu J,Yang C,Li B
Mon Mar 06 00:00:00 EST 2023
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies.
Cell research
Guo L,Mao Q,He J,Liu X,Piao X,Luo L,Hao X,Yu H,Song Q,Xiao B,Fan D,Gao Z,Jia Y
Sat Jul 01 00:00:00 EDT 2023
Acetylation regulates the nucleocytoplasmic distribution and oncogenic function of karyopherin alpha 2 in lung adenocarcinoma.
Biochemical and biophysical research communications
Feng HP,Liu YC,Wang CL,Liao WC,Yu JS,Yu CJ
Sun Jun 04 00:00:00 EDT 2023
The hnRNP C tetramer binds to CBC on mRNA and impedes PHAX recruitment for the classification of RNA polymerase II transcripts.
Nucleic acids research
Dantsuji S,Ohno M,Taniguchi I
Wed Feb 22 00:00:00 EST 2023
UVA1 irradiation attenuates collagen production via Ficz/AhR/MAPK signaling activation in scleroderma.
International immunopharmacology
Shi Y,Xiao Y,Yu J,Liu J,Liu L,Ding Y,Qiu X,Zhan Y,Tang R,Zeng Z,Xiao R
Wed Mar 01 00:00:00 EST 2023
The STAT1/HMGB1/NF-κB pathway in chronic inflammation and kidney injury after cisplatin exposure.
Theranostics
Fu Y,Xiang Y,Wang Y,Liu Z,Yang D,Zha J,Tang C,Cai J,Chen G,Dong Z
Fri Jun 09 00:00:00 EDT 2023
Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zuo Y,Zhan L,Wen H,Xue J,Tan Y,Sun W,Xu E
Wed Mar 01 00:00:00 EST 2023
Mechanisms Underlying the Suppression of IL-1β Expression by Magnesium Hydroxide Nanoparticles.
Biomedicines
Koga A,Thongsiri C,Kudo D,Phuong DND,Iwamoto Y,Fujii W,Nagai-Yoshioka Y,Yamasaki R,Ariyoshi W
Thu Apr 27 00:00:00 EDT 2023
CRISPR/Cas9 based gene editing of Frizzled class receptor 6 (FZD6) reveals its role in depressive symptoms through disrupting Wnt/β-catenin signaling pathway.
Journal of advanced research
Han H,Xu M,Wang J,Li MD,Yang Z
Wed Jun 14 00:00:00 EDT 2023
Microcystin‑leucine arginine promotes colorectal cancer cell proliferation by activating the PI3K/Akt/Wnt/β‑catenin pathway.
Oncology reports
Tang Y,Yi X,Zhang X,Liu B,Lu Y,Pan Z,Yu T,Feng W
Sun Jan 01 00:00:00 EST 2023
eIF2α incites photoreceptor cell and retina damage by all-trans-retinal.
The Journal of biological chemistry
He D,Tao L,Cai B,Chen X,Wang Y,Li S,Liao C,Chen Y,Chen J,Liu Z,Wu Y
Mon May 01 00:00:00 EDT 2023
Transcription Factor-Mediated Differentiation of Motor Neurons from Human Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Wu J,Tang Y
Thu Dec 15 00:00:00 EST 2022
Transcription Factor-Mediated Differentiation of Motor Neurons from Human Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Wu J,Tang Y
Thu Dec 15 00:00:00 EST 2022
Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway.
Stem cell research & therapy
Huang X,Kou X,Zhan T,Wei G,He F,Mao X,Yang H
Sat Apr 15 00:00:00 EDT 2023
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Cell biology and toxicology
Bian Y,Yin G,Wang G,Liu T,Liang L,Yang X,Zhang W,Tang D
Sun Oct 01 00:00:00 EDT 2023
Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1.
British journal of pharmacology
Chen L,Liang B,Xia S,Wang F,Li Z,Shao J,Zhang Z,Chen A,Zheng S,Zhang F
Sun Oct 01 00:00:00 EDT 2023
LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion.
Nature cell biology
Jung-Garcia Y,Maiques O,Monger J,Rodriguez-Hernandez I,Fanshawe B,Domart MC,Renshaw MJ,Marti RM,Matias-Guiu X,Collinson LM,Sanz-Moreno V,Carlton JG
Sun Jan 01 00:00:00 EST 2023
LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion.
Nature cell biology
Jung-Garcia Y,Maiques O,Monger J,Rodriguez-Hernandez I,Fanshawe B,Domart MC,Renshaw MJ,Marti RM,Matias-Guiu X,Collinson LM,Sanz-Moreno V,Carlton JG
Sun Jan 01 00:00:00 EST 2023
Epigenetic plasticity safeguards heterochromatin configuration in mammals.
Nucleic acids research
Fukuda K,Shimi T,Shimura C,Ono T,Suzuki T,Onoue K,Okayama S,Miura H,Hiratani I,Ikeda K,Okada Y,Dohmae N,Yonemura S,Inoue A,Kimura H,Shinkai Y
Fri Jul 07 00:00:00 EDT 2023
Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43.
Journal of virology
Huang SN,Pan YT,Zhou YP,Wang XZ,Mei MJ,Yang B,Li D,Zeng WB,Cheng S,Sun JY,Cheng H,Zhao F,Luo MH
Wed May 31 00:00:00 EDT 2023
Arachidonic acid impairs the function of the blood-testis barrier via triggering mitochondrial complex-ROS-P38 MAPK axis in hyperthermal Sertoli cells.
Ecotoxicology and environmental safety
Hu Y,Hu H,Yin L,Wang L,Luo K,Luo N
Wed Mar 01 00:00:00 EST 2023
Linear ubiquitination improves NFAT1 protein stability and facilitates NFAT1 signalling in Kawasaki disease.
The FEBS journal
Miao Y,Qian G,Zhang R,Yuan Y,Zuo Y,Ding Y,Li X,Tang Y,Zheng H,Lv H
Fri Sep 01 00:00:00 EDT 2023
Pseudorabies Virus Infection Activates the TLR-NF-κB Axis and AIM2 Inflammasome To Enhance Inflammatory Responses in Mice.
Journal of virology
Zhou Q,Zhang L,Lin Q,Liu H,Ye G,Liu X,Jiao S,Li J,Tang Y,Shi D,Huang L,Weng C
Thu Mar 30 00:00:00 EDT 2023
P4HA2 induces hepatic ductular reaction and biliary fibrosis in chronic cholestatic liver diseases.
Hepatology (Baltimore, Md.)
Zhang J,Lyu Z,Li B,You Z,Cui N,Li Y,Li Y,Huang B,Chen R,Chen Y,Peng Y,Fang J,Wang Q,Miao Q,Tang R,Gershwin ME,Lian M,Xiao X,Ma X
Sat Jul 01 00:00:00 EDT 2023
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
International immunopharmacology
Wang J,Ren B,Yang Y,Li Y
Mon May 01 00:00:00 EDT 2023
Effects of Sepsis Serum on the Fate of Adipose Tissue-Derived Stem Cells.
Frontiers in bioscience (Landmark edition)
Fang J,Lu R,Lin Y,Wang H,Wei H,Wang J,Liu Q,Liu H,Zhou Z,Zhang L,Pan R,Chen Y
Thu Apr 06 00:00:00 EDT 2023
Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids.
Bioorganic & medicinal chemistry
Liu P,Cheng M,Guo J,Cao D,Luo J,Wan Y,Fang Y,Jin Y,Xie SS,Liu J
Sun Jan 15 00:00:00 EST 2023
Involvement of canonical Wnt/β-catenin signaling in the extinction of auditory fear conditioning in male mice.
Behavioural brain research
Xu N,Geng L,Yan X,Niu A,Yu H,Su B
Mon May 08 00:00:00 EDT 2023
Mitochondrial transplant after ischemia reperfusion promotes cellular salvage and improves lung function during ex-vivo lung perfusion.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Cloer CM,Givens CS,Buie LK,Rochelle LK,Lin YT,Popa S,Shelton RVM,Zhan J,Zimmerman TR,Jones BG,Lesesne Z,Hogan SS,Petersen TH
Mon May 01 00:00:00 EDT 2023
Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Peng P,Ren Y,Wan F,Tan M,Wu H,Shen J,Qian C,Liu X,Xiang Y,Yu Q,Zhang L,Si Y,Liu Y
Tue Aug 01 00:00:00 EDT 2023
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length.
Frontiers in cell and developmental biology
Kliszczak M,Moralli D,Jankowska JD,Bryjka P,Subha Meem L,Goncalves T,Hester SS,Fischer R,Clynes D,Green CM
Sat Jul 01 00:00:00 EDT 2023
IKKα aggravates renal fibrogenesis by positively regulating the Wnt/β-catenin pathway.
Immunology
Zhang H,Pan B,Huang W,Ma M,Zhang F,Jiang L,Qian C,Wan X,Cao C
Sun Jan 01 00:00:00 EST 2023
SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction.
Virus research
Nie Y,Mou L,Long Q,Deng D,Hu R,Cheng J,Wu J
Sat Apr 15 00:00:00 EDT 2023
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing.
Oncogene
Yu XM,Li SJ,Yao ZT,Xu JJ,Zheng CC,Liu ZC,Ding PB,Jiang ZL,Wei X,Zhao LP,Shi XY,Li ZG,Xu WW,Li B
Wed Mar 01 00:00:00 EST 2023
Syringaresinol attenuates osteoarthritis via regulating the NF-κB pathway.
International immunopharmacology
Wang X,Wang D,Deng B,Yan L
Mon May 01 00:00:00 EDT 2023
Promoting TFEB nuclear localization with curcumin analog C1 attenuates sensory hair cell injury and delays age-related hearing loss in C57BL/6 mice.
Neurotoxicology
He W,Wu F,Xiong H,Zeng J,Gao Y,Cai Z,Pang J,Zheng Y
Wed Mar 01 00:00:00 EST 2023
Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway.
Journal of advanced research
Zhang J,Wang N,Zheng Y,Yang B,Wang S,Wang X,Pan B,Wang Z
Mon May 01 00:00:00 EDT 2023
Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.
Cell death and differentiation
Qin J,Huang T,Wang Z,Zhang X,Wang J,Dang Q,Cui D,Wang X,Zhai Y,Zhao L,Lu G,Shao C,Li S,Liu H,Liu Z
Sun Jan 01 00:00:00 EST 2023
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
Cellular and molecular gastroenterology and hepatology
Yuan J,Lv T,Yang J,Wu Z,Yan L,Yang J,Shi Y,Jiang L
Thu Jan 26 00:00:00 EST 2023
Trans-anethole exerts protective effects on lipopolysaccharide-induced acute jejunal inflammation of broilers via repressing NF-κB signaling pathway.
Poultry science
Tong Y,Yu C,Chen S,Zhang X,Yang Z,Wang T
Wed Feb 01 00:00:00 EST 2023
Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus.
Cellular and molecular neurobiology
An D,Qi X,Li K,Xu W,Wang Y,Chen X,Sha S,Wu C,Du Y,Chen L
Sat Apr 01 00:00:00 EDT 2023
Induction of ferroptosis by HO-1 contributes to retinal degeneration in mice with defective clearance of all-trans-retinal.
Free radical biology & medicine
Chen C,Yang K,He D,Yang B,Tao L,Chen J,Wu Y
Sun Jan 01 00:00:00 EST 2023
ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response.
Molecular medicine (Cambridge, Mass.)
Liu Y,Zhang L,Zhang S,Liu J,Li X,Yang K,Yang D,Liu Y,Sun L,Liu F,Xiao L
Mon Apr 24 00:00:00 EDT 2023
Multi-omics and network pharmacology study reveals the effects of Dengzhan Shengmai capsule against neuroinflammatory injury and thrombosis induced by ischemic stroke.
Journal of ethnopharmacology
Ye J,Huang F,Zeng H,Xu X,Wu G,Tian S,Zhao J,Zhang W
Thu Apr 06 00:00:00 EDT 2023
The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway.
Cell death & disease
Li H,Jiang Y,Hu J,Xu J,Chen L,Zhang G,Zhao J,Zong S,Guo Z,Li X,Zhao X,Jing Z
Fri Jan 13 00:00:00 EST 2023
Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro.
Oncology letters
Kogami M,Abe S,Nakamura H,Aoshiba K
Sat Jul 01 00:00:00 EDT 2023
Myb Repression Mediates Stat5b-knockdown-induced Apoptosis and Inhibits Proliferation of Glioblastoma Stem Cells.
Cancer genomics & proteomics
Moyama C,Fujita M,Okamoto H,Ii H,Nakata S
Tue Mar 07 00:00:00 EST 2023
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Cell host & microbe
Zeng Y,Wu R,Wang F,Li S,Li L,Li Y,Qin P,Wei M,Yang J,Wu J,Chen A,Ke G,Yan Z,Yang H,Chen Z,Wang Z,Xiao W,Jiang Y,Chen X,Zeng Z,Zhao X,Chen P,Gong S
Wed May 10 00:00:00 EDT 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 EDT 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
Upregulation of CDGSH iron sulfur domain 2 attenuates cerebral ischemia/reperfusion injury.
Neural regeneration research
Hu M,Huang J,Chen L,Sun XR,Yao ZM,Tong XH,Jin WJ,Zhang YX,Dong SY
Sat Jul 01 00:00:00 EDT 2023
Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
iScience
Miyagi T,Ueda K,Sugimoto M,Yagi T,Ito D,Yamazaki R,Narumi S,Hayamizu Y,Uji-I H,Kuroda M,Kanekura K
Fri Jun 16 00:00:00 EDT 2023
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Journal of ethnopharmacology
Zhu Y,Han Y,Wang W,Liang G,Qi J
Sat Jul 15 00:00:00 EDT 2023
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Oxidative medicine and cellular longevity
Chen Y,Zhang H,Li Y,Wang T
Mon Feb 06 00:00:00 EST 2023
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Immunopharmacology and immunotoxicology
Wang X,Yang J,Wang W,Li Y,Yang Y
Sun Oct 01 00:00:00 EDT 2023
Transforming acidic coiled-coil containing protein 3 suppresses influenza A virus replication by impeding viral endosomal trafficking and nuclear import.
Veterinary microbiology
Deng L,Zhao L,Jin J,Qiao B,Zhang X,Chang L,Zheng L,Dankar S,Ping J
Sat Jul 01 00:00:00 EDT 2023
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Cell death & disease
Zheng G,Su Y,Wei L,Yao Y,Wang Y,Luo X,Wang X,Ruan XZ,Li D,Chen Y
Thu Apr 06 00:00:00 EDT 2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mi Y,Wei C,Sun L,Liu H,Zhang J,Luo J,Yu X,He J,Ge H,Liu P
Sun Jan 01 00:00:00 EST 2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mi Y,Wei C,Sun L,Liu H,Zhang J,Luo J,Yu X,He J,Ge H,Liu P
Sun Jan 01 00:00:00 EST 2023
Gut microbiota-derived 3-phenylpropionic acid promotes intestinal epithelial barrier function via AhR signaling.
Microbiome
Hu J,Chen J,Xu X,Hou Q,Ren J,Yan X
Mon May 08 00:00:00 EDT 2023
TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly.
Cell reports
Klump BM,Perez GI,Patrick EM,Adams-Boone K,Cohen SB,Han L,Yu K,Schmidt JC
Tue Jun 27 00:00:00 EDT 2023
Pioglitazone can improve liver sex hormone-binding globulin levels and lipid metabolism in polycystic ovary syndrome by regulating hepatocyte nuclear factor-4α.
The Journal of steroid biochemistry and molecular biology
Zhao H,Wang D,Xing C,Lv B,Wang X,He B
Mon May 01 00:00:00 EDT 2023
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
The Journal of cell biology
Wang X,Jiang X,Li B,Zheng J,Guo J,Gao L,Du M,Weng X,Li L,Chen S,Zhang J,Fang L,Liu T,Wang L,Liu W,Neculai D,Sun Q
Mon May 01 00:00:00 EDT 2023
Targeting mTOR/YY1 signaling pathway by quercetin through CYP7A1-mediated cholesterol-to-bile acids conversion alleviated type 2 diabetes mellitus induced hepatic lipid accumulation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang T,Wang Y,Cao X,Peng Y,Huang J,Chen L,Pang J,Jiang Z,Qian S,Liu Y,Ying C,Wang T,Zhang F,Lu Q,Yin X
Mon May 01 00:00:00 EDT 2023
Metformin alleviates ethanol-induced cardiomyocyte injury by activating AKT/Nrf2 signaling in an ErbB2-dependent manner.
Molecular biology reports
Chen Y,Zhu S,Lin Z,Zhang Y,Jin C,He S,Chen X,Zhou X
Sat Apr 01 00:00:00 EDT 2023
AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Cai Z,Shen Z,Zhao J,Zhang H,Guo Z,Xia Q,Liang H,Liu J,Tan L,Sheng H,Zhu S
Thu Jun 01 00:00:00 EDT 2023
Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway.
International immunopharmacology
Li X,Yu X,He S,Li J
Sat Jul 01 00:00:00 EDT 2023
Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway.
Frontiers in pharmacology
Chen T,Hu Y,Lu L,Zhao Q,Tao X,Ding B,Chen S,Zhu J,Guo X,Lin Z
Tue Mar 28 00:00:00 EDT 2023
Dynamics and Composition of Small Heat Shock Protein Condensates and Aggregates.
Journal of molecular biology
Joosten J,van Sluijs B,Vree Egberts W,Emmaneel M,Jansen PWTC,Vermeulen M,Boelens W,Bonger KM,Spruijt E
Sat Jul 01 00:00:00 EDT 2023
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.
Nature biotechnology
Yarnall MTN,Ioannidi EI,Schmitt-Ulms C,Krajeski RN,Lim J,Villiger L,Zhou W,Jiang K,Garushyants SK,Roberts N,Zhang L,Vakulskas CA,Walker JA,Kadina AP,Zepeda AE,Holden K,Ma H,Xie J,Gao G,Foquet L,Bial G,Donnelly SK,Miyata Y,Radiloff DR,Henderson JM,Ujita A,Abudayyeh OO,Gootenberg JS
Sat Apr 01 00:00:00 EDT 2023
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.
Nature biotechnology
Yarnall MTN,Ioannidi EI,Schmitt-Ulms C,Krajeski RN,Lim J,Villiger L,Zhou W,Jiang K,Garushyants SK,Roberts N,Zhang L,Vakulskas CA,Walker JA,Kadina AP,Zepeda AE,Holden K,Ma H,Xie J,Gao G,Foquet L,Bial G,Donnelly SK,Miyata Y,Radiloff DR,Henderson JM,Ujita A,Abudayyeh OO,Gootenberg JS
Sat Apr 01 00:00:00 EDT 2023
Analyses of Transcriptomics upon IL-1β-Stimulated Mouse Chondrocytes and the Protective Effect of Catalpol through the NOD2/NF-κB/MAPK Signaling Pathway.
Molecules (Basel, Switzerland)
Pang Y,Zhao L,Ji X,Guo K,Yin X
Tue Feb 07 00:00:00 EST 2023
African Swine Fever Virus H240R Protein Inhibits the Production of Type I Interferon through Disrupting the Oligomerization of STING.
Journal of virology
Ye G,Liu H,Liu X,Chen W,Li J,Zhao D,Wang G,Feng C,Zhang Z,Zhou Q,Zheng J,Bu Z,Weng C,Huang L
Thu Sep 28 00:00:00 EDT 2023
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Nucleic acids research
Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J
Tue Mar 21 00:00:00 EDT 2023
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Drug design, development and therapy
Li Y,Zhu S,Luo J,Tong Y,Zheng Y,Ji L,He Z,Jing Q,Huang J,Zhang Y,Bi Q
Thu Jun 01 00:00:00 EDT 2023
UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage.
Biochimica et biophysica acta. Gene regulatory mechanisms
Hu X,Zou R,Zhang Z,Ji J,Li J,Huo XY,Liu D,Ge MX,Cui MK,Wu MZ,Li ZP,Wang Q,Zhang X,Zhang ZR
Thu Jun 01 00:00:00 EDT 2023
Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure.
Environmental toxicology and pharmacology
Piell KM,Petri BJ,Head KZ,Wahlang B,Xu R,Zhang X,Pan J,Rai SN,de Silva K,Chariker JH,Rouchka EC,Tan M,Li Y,Cave MC,Klinge CM
Thu Jun 01 00:00:00 EDT 2023
LATS-regulated nuclear-cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial-mesenchymal transition.
Molecular carcinogenesis
Zhang F,Gao J,Liu X,Sun Y,Liu L,Hu B,Wang Z,Shi J,Guo W,Zhang S
Sat Jul 01 00:00:00 EDT 2023
ER export signals mediate plasma membrane localization of transmembrane protein TMEM72.
The FEBS journal
Ding J,Matsumiya T,Miki Y,Hayakari R,Shiba Y,Kawaguchi S,Seya K,Imaizumi T
Mon May 01 00:00:00 EDT 2023
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
Food & function
Meng Z,Lu J,Ge G,Wang G,Zhang R,Li Y,Guan S,Lu J
Tue Jan 03 00:00:00 EST 2023
Aloperine alleviates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome activation.
International immunopharmacology
Zeng J,Liu J,Huang JH,Fu SP,Wang XY,Xi C,Cui YR,Qu F
Sat Jul 01 00:00:00 EDT 2023
Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin α7 is counteracted by TBK1-p62 axis-mediated autophagy.
Cellular & molecular immunology
Wang X,Jiang L,Wang G,Shi W,Hu Y,Wang B,Zeng X,Tian G,Deng G,Shi J,Liu L,Li C,Chen H
Sat Oct 01 00:00:00 EDT 2022
Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
The Journal of clinical investigation
Yan J,Chen Y,Patel AJ,Warda S,Lee CJ,Nixon BG,Wong EW,Miranda-Román MA,Yang N,Wang Y,Pachai MR,Sher J,Giff E,Tang F,Khurana E,Singer S,Liu Y,Galbo PM,Maag JL,Koche RP,Zheng D,Antonescu CR,Deng L,Li MO,Chen Y,Chi P
Thu Sep 01 00:00:00 EDT 2022
Importin-Mediated Pathological Tau Nuclear Translocation Causes Disruption of the Nuclear Lamina, TDP-43 Mislocalization and Cell Death.
Frontiers in molecular neuroscience
Candia RF,Cohen LS,Morozova V,Corbo C,Alonso AD
Fri Feb 17 00:00:00 EST 2023
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
International journal of oncology
Wang R,Peng C,Song J,Hua Y,Wu Q,Deng L,Cao Y,Zhang J,Zhang L,Wu L,Hou L
Tue Mar 01 00:00:00 EST 2022
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
International journal of oncology
Wang R,Peng C,Song J,Hua Y,Wu Q,Deng L,Cao Y,Zhang J,Zhang L,Wu L,Hou L
Tue Mar 01 00:00:00 EST 2022
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Journal of cellular and molecular medicine
Wang N,Huang R,Yang K,He Y,Gao Y,Dong D
Tue Feb 01 00:00:00 EST 2022
Ginsenoside Rd ameliorates high glucose-induced retinal endothelial injury through AMPK-STRT1 interdependence.
Pharmacological research
Tang K,Qin W,Wei R,Jiang Y,Fan L,Wang Z,Tan N
Sun May 01 00:00:00 EDT 2022
CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.
Molecular metabolism
Zeng H,Qin H,Liao M,Zheng E,Luo X,Xiao A,Li Y,Chen L,Wei L,Zhao L,Ruan XZ,Yang P,Chen Y
Tue Mar 01 00:00:00 EST 2022
Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.
Journal of cell science
Iadevaia V,Burke JM,Eke L,Moller-Levet C,Parker R,Locker N
Tue Feb 15 00:00:00 EST 2022
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shi Y,Chen J,Li S,Wu Y,Yu C,Ni L,Xiao J,Shao Z,Zhu H,Wang J,Wang X,Zhang X
Fri Apr 01 00:00:00 EDT 2022
Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis.
Communications biology
Miyake Y,Obana M,Yamamoto A,Noda S,Tanaka K,Sakai H,Tatsumoto N,Makino C,Kanemoto S,Shioi G,Tanaka S,Maeda M,Okada Y,Imaizumi K,Asanuma K,Fujio Y
Fri Jul 22 00:00:00 EDT 2022
IGF-1R/YAP signaling pathway is involved in collagen V-induced insulin biosynthesis and secretion in rat islet INS-1 cells.
Connective tissue research
Zhu Y,Chen S,Liu W,Xu F,Lu J,Hayashi T,Mizuno K,Hattori S,Fujisaki H,Ikejima T
Thu Sep 01 00:00:00 EDT 2022
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Inflammation
Chen S,Huang Y,Su H,Zhu W,Wei Y,Long Y,Shi Y,Wei J
Mon Aug 01 00:00:00 EDT 2022
LATS1 is a central signal transmitter for achieving full type-I interferon activity.
Science advances
Zuo Y,He J,Liu S,Xu Y,Liu J,Qiao C,Zang L,Sun W,Yuan Y,Zhang H,Chen X,Jin L,Miao Y,Huang F,Ren T,Wang J,Qian F,Zhu C,Zhang W,Liu Y,Xu G,Ma F,Zheng H
Fri Apr 08 00:00:00 EDT 2022
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
BMC medicine
Zhan Y,Zhang Z,Liu Y,Fang Y,Xie Y,Zheng Y,Li G,Liang L,Ding Y
Wed Oct 19 00:00:00 EDT 2022
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
The Journal of experimental medicine
Tao X,Zhang R,Du R,Yu T,Yang H,Li J,Wang Y,Liu Q,Zuo S,Wang X,Lazarus M,Zhou L,Wang B,Yu Y,Shen Y
Mon May 02 00:00:00 EDT 2022
N-glycosylation stabilizes MerTK and promotes hepatocellular carcinoma tumor growth.
Redox biology
Liu Y,Lan L,Li Y,Lu J,He L,Deng Y,Fei M,Lu JW,Shangguan F,Lu JP,Wang J,Wu L,Huang K,Lu B
Mon Aug 01 00:00:00 EDT 2022
Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF- κ B and PI3K/AKT Signaling In Vitro and In Vivo.
Chinese journal of integrative medicine
Xuan L,Hu JH,Bi R,Liu SQ,Wang CX
Fri Apr 01 00:00:00 EDT 2022
PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathway.
Redox biology
Lee DH,Park JS,Lee YS,Bae SH
Fri Apr 01 00:00:00 EDT 2022
TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.
Contrast media & molecular imaging
Cui H,Zhang L,Chen B,Zhang F,Xu H,Ma G,Cao L,Wang M
Thu Jul 21 00:00:00 EDT 2022
Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through notch signaling.
iScience
Liu P,Li Y,Li M,Zhou H,Zhang H,Zhang Y,Xu J,Xu Y,Zhang J,Xia B,Cheng H,Ke Y,Zhang X
Fri Mar 18 00:00:00 EDT 2022
Effect of Lycium barbarum Polysaccharide on Decreasing Serum Amyloid A3 Expression through Inhibiting NF-κB Activation in a Mouse Model of Diabetic Nephropathy.
Analytical cellular pathology (Amsterdam)
Wan F,Ma F,Wu J,Qiao X,Chen M,Li W,Ma L
Mon Apr 04 00:00:00 EDT 2022
Induction of ferroptosis selectively eliminates senescent tubular cells.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Liao CM,Wulfmeyer VC,Chen R,Erlangga Z,Sinning J,von Mässenhausen A,Sörensen-Zender I,Beer K,von Vietinghoff S,Haller H,Linkermann A,Melk A,Schmitt R
Thu Sep 01 00:00:00 EDT 2022
Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways.
Biochemical pharmacology
Tu Y,Tan L,Lu T,Wang K,Wang H,Han B,Zhao Y,Chen H,Li Y,Chen H,Chen M,He C
Tue Mar 01 00:00:00 EST 2022
Phellinus linteus polysaccharides mediates acetaminophen-induced hepatotoxicity via activating AMPK/Nrf2 signaling pathways.
Aging
Zhao L,Zheng L,Li Z,Jin M,Wang Q,Cheng J,Li J,Feng H
Thu Sep 01 00:00:00 EDT 2022
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axis.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Gao Y,Ma K,Kang Y,Liu W,Liu X,Long X,Hayashi T,Hattori S,Mizuno K,Fujisaki H,Ikejima T
Thu Sep 01 00:00:00 EDT 2022
LINC02535/miR-30a-5p/GALNT3 axis contributes to lung adenocarcinoma progression via the NF- κ B signaling pathway.
Cell cycle (Georgetown, Tex.)
Li Y,Zhao J,Zhang W,Wang A,Jiao M,Cai X,Zhu J,Liu Z,Huang JA
Thu Dec 01 00:00:00 EST 2022
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Cell communication and signaling : CCS
Wen P,Wang H,Li Y,Sui X,Hou Z,Guo X,Xue W,Liu D,Wang Y,Gao J
Fri Oct 28 00:00:00 EDT 2022
Paraquat Inhibits Autophagy Via Intensifying the Interaction Between HMGB1 and α-Synuclein.
Neurotoxicity research
Wang K,Zhang B,Zhang B,Wu K,Tian T,Yan W,Huang M
Fri Apr 01 00:00:00 EDT 2022
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Frontiers in oncology
Liu H,Zhao L,Wang M,Yang K,Jin Z,Zhao C,Shi G
Sat Apr 09 00:00:00 EDT 2022
Foxf2 represses bone formation via Wnt2b/β-catenin signaling.
Experimental & molecular medicine
Tanaka T,Takahashi A,Kobayashi Y,Saito M,Xiaolong S,Jingquan C,Ito Y,Kato T,Ochi H,Sato S,Yoshii T,Okawa A,Carlsson P,Inose H
Wed Jun 01 00:00:00 EDT 2022
C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis.
Experimental neurology
Gao Z,Zhang C,Feng Z,Liu Z,Yang Y,Yang K,Chen L,Yao R
Tue Feb 01 00:00:00 EST 2022
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
Frontiers in pharmacology
Luo Q,Ling Y,Li Y,Qu X,Shi Q,Zheng S,Li Y,Huang Y,Zhou X
Tue Sep 20 00:00:00 EDT 2022
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Pharmacological research
Li X,Zhang Y,Zhao Y,Zhou Y,Han Q,Yang Y,Zhang L,Shi L,Jin X,Zhang R,Gao H,Xue G,Li D,Zhang ZR,Lu Y,Yang B,Pan Z
Mon Aug 01 00:00:00 EDT 2022
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson's Disease Model.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Aug 06 00:00:00 EDT 2022
Electrostatic anti-CD33-antibody-protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia.
Journal of hematology & oncology
Bäumer N,Scheller A,Wittmann L,Faust A,Apel M,Nimmagadda SC,Geyer C,Grunert K,Kellmann N,Peipp M,Kailayangiri S,Gutierrez Suburu ME,Strassert CA,Schenk M,Greune L,Rüter C,Dersch P,Hartmann W,Rossig C,Neri D,Müller-Tidow C,Schwöppe C,Schliemann C,Khandanpour C,Lenz G,Berdel WE,Bäumer S
Thu Dec 01 00:00:00 EST 2022
Hinokitiol functions as a ferroptosis inhibitor to confer neuroprotection.
Free radical biology & medicine
Xi J,Zhang Z,Wang Z,Wu Q,He Y,Xu Y,Ding Z,Zhao H,Da H,Zhang F,Zhao H,Fang J
Thu Sep 01 00:00:00 EDT 2022
An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms.
Nature communications
Yao H,Song W,Cao R,Ye C,Zhang L,Chen H,Wang J,Shi Y,Li R,Li Y,Liu X,Zhou X,Shao R,Li L
Tue Sep 20 00:00:00 EDT 2022
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Proceedings of the National Academy of Sciences of the United States of America
Li P,Wu J,Liu S,Lu R,Jiang H,Wang N,Luo M,Guo L,Xiao J,Bu L,Liu L,Xing F,Peng H,Li C,Ma L,Zhao B,Zhou Z,Guo D
Tue Dec 06 00:00:00 EST 2022
Rapid and robust derivation of mesenchymal stem cells from human pluripotent stem cells via temporal induction of neuralized ectoderm.
Cell & bioscience
Jin W,He Y,Li T,Long F,Qin X,Yuan Y,Gao G,Shakhawat HM,Liu X,Jin G,Zhou Z
Tue Mar 15 00:00:00 EDT 2022
Rapid and robust derivation of mesenchymal stem cells from human pluripotent stem cells via temporal induction of neuralized ectoderm.
Cell & bioscience
Jin W,He Y,Li T,Long F,Qin X,Yuan Y,Gao G,Shakhawat HM,Liu X,Jin G,Zhou Z
Tue Mar 15 00:00:00 EDT 2022
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang J,Zhang L,Cao H,Shi X,Zhang X,Gao Z,Ikeda K,Yan T,Jia Y,Xu F
Sun May 01 00:00:00 EDT 2022
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
The Journal of biological chemistry
Ji R,Shi Q,Cao Y,Zhang J,Zhao C,Zhao H,Sayyed Y,Fu L,Li LY
Wed Jun 01 00:00:00 EDT 2022
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Molecular cell
Jiang B,Zhang J,Zhao G,Liu M,Hu J,Lin F,Wang J,Zhao W,Ma H,Zhang C,Wu C,Yao L,Liu Q,Chen X,Cao Y,Zheng Y,Zhang C,Han A,Lin D,Li Q
Thu May 19 00:00:00 EDT 2022
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
Journal of agricultural and food chemistry
Zhao Y,Zhang R,Wang Z,Chen Z,Wang G,Guan S,Lu J
Wed Oct 12 00:00:00 EDT 2022
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
The EMBO journal
Huang Q,Wu D,Zhao J,Yan Z,Chen L,Guo S,Wang D,Yuan C,Wang Y,Liu X,Xing J
Wed Jun 01 00:00:00 EDT 2022
Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway.
Frontiers in pharmacology
Hu X,Li C,Wang Q,Wei Z,Chen T,Wang Y,Li Y
Sat Jul 16 00:00:00 EDT 2022
Baicalein Prevents Fructose-Induced Hepatic Steatosis in Rats: In the Regulation of Fatty Acid De Novo Synthesis, Fatty Acid Elongation and Fatty Acid Oxidation.
Frontiers in pharmacology
Li P,Zhang R,Wang M,Chen Y,Chen Z,Ke X,Zuo L,Wang J
Tue Jul 19 00:00:00 EDT 2022
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
Molecular and cellular biochemistry
Dubey PK,Patil M,Singh S,Dubey S,Ahuja P,Verma SK,Krishnamurthy P
Sat Jan 01 00:00:00 EST 2022
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
International journal of radiation oncology, biology, physics
Chen G,Kong P,Yang M,Hu W,Prise KM,Yu KN,Cui S,Qin F,Meng G,Almahi WA,Nie L,Han W
Fri Apr 01 00:00:00 EDT 2022
A Redox-Silent Analogue of Tocotrienol May Break the Homeostasis of Proteasomes in Human Malignant Mesothelioma Cells by Inhibiting STAT3 and NRF1.
International journal of molecular sciences
Ishii K,Fusegi M,Mori T,Teshima K,Ninomiya N,Kohno K,Sato A,Ishida T,Miyakoshi Y,Yano T
Mon Feb 28 00:00:00 EST 2022
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Phytotherapy research : PTR
Wu XY,Wang T,Hu HX,Zhang K,Zhao Y,Zhao BB,Lou HX,Wang XN,Shen T
Fri Apr 01 00:00:00 EDT 2022
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
The EMBO journal
Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L
Thu Dec 01 00:00:00 EST 2022
Repeated Administration of Cisplatin Transforms Kidney Fibroblasts through G2/M Arrest and Cellular Senescence.
Cells
Yu JB,Lee DS,Padanilam BJ,Kim J
Wed Nov 02 00:00:00 EDT 2022
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Nature communications
Li X,Ding K,Li X,Yuan B,Wang Y,Yao Z,Wang S,Huang H,Xu B,Xie L,Deng T,Chen XW,Chen Z
Thu Aug 04 00:00:00 EDT 2022
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Nature aging
Liang W,Chen Q,Cheng S,Wei R,Li Y,Yao C,Ouyang Z,Kang D,Chen A,Liu Z,Li K,Bai X,Li Q,Huang B
Sat Oct 01 00:00:00 EDT 2022
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Chemical biology & drug design
Zhu W,Tang H,Cao L,Zhang J,Li J,Ma D,Guo C
Fri Jul 01 00:00:00 EDT 2022
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion.
Frontiers in pharmacology
Tang L,Li T,Zhang B,Zhang Z,Sun X,Zhu Y,Feng B,Su Z,Yang L,Li H,Liu H,Chen Y,Dai Z,Zheng X,Li M,Li C,Zhao J,Qiu X,Ye S,Liu H,Zheng G,Li B,Lu C
Wed Feb 16 00:00:00 EST 2022
Characterization of phalloidin-negative nuclear actin filaments in U2OS cells expressing cytoplasmic actin-EGFP.
Genes to cells : devoted to molecular & cellular mechanisms
Nagasaki A,Katoh K,Hoshi M,Doi M,Nakamura C,Uyeda TQP
Sun May 01 00:00:00 EDT 2022
PARK7 is induced to protect against endotoxic acute kidney injury by suppressing NF-κB.
Clinical science (London, England : 1979)
Li H,Liu Z,Wang Y,Wang H,Cai J,Tang C,Dong Z
Thu Dec 22 00:00:00 EST 2022
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Metabolic brain disease
Ren X,Yu J,Guo L,Zhang Z
Sat Oct 01 00:00:00 EDT 2022
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
International immunopharmacology
Cai W,Zhang Y,Jin W,Wei S,Chen J,Zhong C,Zhong Y,Tu C,Peng H
Thu Dec 01 00:00:00 EST 2022
Metabolic Syndrome Ameliorated by 4-Methylesculetin by Reducing Hepatic Lipid Accumulation.
International journal of molecular sciences
Li L,Zhu G,Fu G,Zha W,Li H
Fri Sep 09 00:00:00 EDT 2022
The cancer/testis antigen HORMAD1 mediates epithelial-mesenchymal transition to promote tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway in lung cancer.
Cell death discovery
Liu K,Cheng L,Zhu K,Wang J,Shu Q
Mon Mar 28 00:00:00 EDT 2022
Relationship between Neuroprotective Effects and Structure of Procyanidins.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Apr 02 00:00:00 EDT 2022
Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.
Molecular and cellular endocrinology
Du X,Osoro EK,Chen Q,Yan X,Gao D,Wu L,Ren J,Feng L,Wu N,Lu K,Yang X,Zhong B,Han Y,Zhang F,Li D,Lan X,Lu S
Tue Apr 05 00:00:00 EDT 2022
Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate.
Developmental cell
Tang Y,Zhu L,Cho JS,Li XY,Weiss SJ
Mon Feb 28 00:00:00 EST 2022
Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells.
Frontiers in endocrinology
Morikawa S,Blacher L,Onwumere C,Urano F
Tue Apr 12 00:00:00 EDT 2022
Pitx3 deficiency promotes age-dependent alterations in striatal medium spiny neurons.
Frontiers in aging neuroscience
Chen X,Yang Z,Shao Y,Kim K,Wang Y,Wang Y,Wu H,Xu X,Le W
Fri Nov 03 00:00:00 EDT 2023
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 EDT 2022
A Novel lncRNA Mediates the Delayed Tooth Eruption of Cleidocranial Dysplasia.
Cells
Xin Y,Liu Y,Li J,Liu D,Zhang C,Wang Y,Zheng S
Thu Sep 01 00:00:00 EDT 2022
High-frequency near-infrared diode laser irradiation suppresses IL-1β-induced inflammatory cytokine expression and NF-κB signaling pathways in human primary chondrocytes.
Lasers in medical science
Sakata S,Kunimatsu R,Tsuka Y,Nakatani A,Gunji H,Yanoshita M,Kado I,Ito S,Putranti NAR,Prasetya RC,Hirose N,Tanimoto K
Tue Mar 01 00:00:00 EST 2022
Phosphorylation of Ser82 on IRF3 acts as negative-feedback regulation of IRF3-dependent innate immunity.
The international journal of biochemistry & cell biology
Cheng Q,Yuan L,Guo J,Guo D,Liu X,Li S
Thu Sep 01 00:00:00 EDT 2022
Glycosylated modification of MUC1 maybe a new target to promote drug sensitivity and efficacy for breast cancer chemotherapy.
Cell death & disease
Xi X,Wang J,Qin Y,Huang W,You Y,Zhan J
Tue Aug 16 00:00:00 EDT 2022
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Journal of cardiovascular translational research
Cheng L,Wang H,Maboh R,Mao G,Wu X,Chen H
Sat Oct 01 00:00:00 EDT 2022
Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ip.
Cells
Zhang L,Xu L,Zhang X,Wang K,Tan Y,Li G,Wang Y,Xue T,Sun Q,Cao X,Zhang G,Hu Z,Zhang S,Shi F
Fri Aug 19 00:00:00 EDT 2022
Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling.
Cell communication and signaling : CCS
Zhu P,Jin Z,Kang G,Jia Y,Liu D,Zhang Q,Guo F,Jia Y,Jiao Y,Li J,Sun H,Ma X
Mon Aug 15 00:00:00 EDT 2022
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Journal of agricultural and food chemistry
Chen Y,Zhang H,Li Y,Ji S,Jia P,Wang T
Wed Oct 26 00:00:00 EDT 2022
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Journal of dental sciences
Xi X,Li ZX,Zhao Y,Liu H,Chen S,Liu DX
Fri Apr 01 00:00:00 EDT 2022
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension.
Journal of cellular and molecular medicine
Deng H,Tian X,Sun H,Liu H,Lu M,Wang H
Sun May 01 00:00:00 EDT 2022
Human Cytomegalovirus Utilizes Multiple Viral Proteins to Regulate the Basement Membrane Protein Nidogen 1.
Journal of virology
Kuan MI,Caruso LB,Zavala AG,Rana PSJB,O'Dowd JM,Tempera I,Fortunato EA
Wed Oct 26 00:00:00 EDT 2022
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.
Oncogene
Bell ES,Shah P,Zuela-Sopilniak N,Kim D,Varlet AA,Morival JLP,McGregor AL,Isermann P,Davidson PM,Elacqua JJ,Lakins JN,Vahdat L,Weaver VM,Smolka MB,Span PN,Lammerding J
Thu Sep 01 00:00:00 EDT 2022
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.
Oncogene
Bell ES,Shah P,Zuela-Sopilniak N,Kim D,Varlet AA,Morival JLP,McGregor AL,Isermann P,Davidson PM,Elacqua JJ,Lakins JN,Vahdat L,Weaver VM,Smolka MB,Span PN,Lammerding J
Thu Sep 01 00:00:00 EDT 2022
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.
Oncogene
Bell ES,Shah P,Zuela-Sopilniak N,Kim D,Varlet AA,Morival JLP,McGregor AL,Isermann P,Davidson PM,Elacqua JJ,Lakins JN,Vahdat L,Weaver VM,Smolka MB,Span PN,Lammerding J
Thu Sep 01 00:00:00 EDT 2022
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.
Oncogene
Bell ES,Shah P,Zuela-Sopilniak N,Kim D,Varlet AA,Morival JLP,McGregor AL,Isermann P,Davidson PM,Elacqua JJ,Lakins JN,Vahdat L,Weaver VM,Smolka MB,Span PN,Lammerding J
Thu Sep 01 00:00:00 EDT 2022
Protective activity of tert-butylhydroquinone against oxidative stress and apoptosis induced by glutamate agonizts in R28 cells and mice retina.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dai S,Wang C,Feng L,Zhang C,Zhang W,He Y,Zhou X,Xia X,Chen B,Song W
Mon Aug 01 00:00:00 EDT 2022
Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2.
Viruses
Nakanishi A,Okumura H,Hashita T,Yamashita A,Nishimura Y,Watanabe C,Kamimura S,Hayashi S,Murakami S,Ito K,Iwao T,Ikeda A,Hirose T,Sunazuka T,Tanaka Y,Matsunaga T
Tue Nov 08 00:00:00 EST 2022
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Frontiers in immunology
Huang D,Wang P,Chen J,Li Y,Zhu M,Tang Y,Zhou W
Mon Nov 21 00:00:00 EST 2022
Schisandra chinensis (Turcz.) Baill. essential oil exhibits antidepressant-like effects and against brain oxidative stress through Nrf2/HO-1 pathway activation.
Metabolic brain disease
Tan L,Yang Y,Peng J,Zhang Y,Wu B,He B,Jia Y,Yan T
Sat Oct 01 00:00:00 EDT 2022
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
Journal of translational medicine
Lu B,Chen X,Liu X,Chen J,Qin H,Chen S,Zhao Y
Sat Dec 24 00:00:00 EST 2022
Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo.
Frontiers in pharmacology
Jiang Z,Qi G,Lu W,Wang H,Li D,Chen W,Ding L,Yang X,Yuan H,Zeng Q
Sat Oct 15 00:00:00 EDT 2022
Celastrol inhibits pathologic neovascularization in oxygen-induced retinopathy by targeting the miR-17-5p/HIF-1α/VEGF pathway.
Cell cycle (Georgetown, Tex.)
Zhao K,Jiang Y,Zhang J,Shi J,Zheng P,Yang C,Chen Y
Sat Oct 01 00:00:00 EDT 2022
Dopamine Suppresses Osteogenic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells via AKT/GSK-3β/β-Catenin Signaling Pathway.
Stem cells international
Kuang Z,Chen Z,Tu S,Mai Z,Chen L,Kang X,Chen X,Wei J,Wang Y,Peng Y,Ai H
Sat Jul 16 00:00:00 EDT 2022
Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis.
Cancer science
Zhu Y,Yang Y,Bu H,Huang H,Chen H,Ran J,Qin L,Ni Y,Yao M,Song T,Li M,Yang Y,Guo T,Chao N,Liu Z,Li W,Zhang L
Tue Nov 01 00:00:00 EDT 2022
The miR-33a-5p/CROT axis mediates ovarian cancer cell behaviors and chemoresistance via the regulation of the TGF-β signal pathway.
Frontiers in endocrinology
Li X,Gao X,Yuan J,Wang F,Xu X,Wang C,Liu H,Guan W,Zhang J,Xu G
Tue Sep 20 00:00:00 EDT 2022
Theaflavin Attenuates TBHP-Induced Endothelial Cells Oxidative Stress by Activating PI3K/AKT/Nrf2 and Accelerates Wound Healing in Rats.
Frontiers in bioengineering and biotechnology
Chen D,Wu Z,Wu LN,Jiang J,Hu GN
Tue Mar 22 00:00:00 EDT 2022
Nucleome programming is required for the foundation of totipotency in mammalian germline development.
The EMBO journal
Nagano M,Hu B,Yokobayashi S,Yamamura A,Umemura F,Coradin M,Ohta H,Yabuta Y,Ishikura Y,Okamoto I,Ikeda H,Kawahira N,Nosaka Y,Shimizu S,Kojima Y,Mizuta K,Kasahara T,Imoto Y,Meehan K,Stocsits R,Wutz G,Hiraoka Y,Murakawa Y,Yamamoto T,Tachibana K,Peters JM,Mirny LA,Garcia BA,Majewski J,Saitou M
Mon Jul 04 00:00:00 EDT 2022
Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure-Activity Relationships.
Molecules (Basel, Switzerland)
Zhang D,Li X,He X,Xing Y,Jiang B,Xiu Z,Bao Y,Dong Y
Sat Nov 12 00:00:00 EST 2022
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
JCI insight
Li L,Zhong S,Li R,Liang N,Zhang L,Xia S,Xu X,Chen X,Chen S,Tao Y,Yin H
Fri Apr 08 00:00:00 EDT 2022
Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts.
Journal of cellular physiology
Dubey S,Dubey PK,Umeshappa CS,Ghebre YT,Krishnamurthy P
Fri Apr 01 00:00:00 EDT 2022
miR-1260b inhibits periodontal bone loss by targeting ATF6β mediated regulation of ER stress.
Frontiers in cell and developmental biology
Hayashi C,Fukuda T,Kawakami K,Toyoda M,Nakao Y,Watanabe Y,Shinjo T,Sano T,Iwashita M,Yotsumoto K,Shida M,Taketomi T,Sanui T,Uchiumi T,Kanematsu T,Nishimura F
Thu Dec 22 00:00:00 EST 2022
The Antimicrobial Peptides Human β-Defensins Induce the Secretion of Angiogenin in Human Dermal Fibroblasts.
International journal of molecular sciences
Umehara Y,Takahashi M,Yue H,Trujillo-Paez JV,Peng G,Nguyen HLT,Okumura K,Ogawa H,Niyonsaba F
Mon Aug 08 00:00:00 EDT 2022
BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway.
Free radical biology & medicine
Li T,Geng Z,Zhang J,Xu L,Zhu X
Sun Nov 20 00:00:00 EST 2022
C1q/tumor necrosis factor-related protein 9 protects cultured chondrocytes from IL-1β-induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis.
Environmental toxicology
Wang B,Li Y,Hu S,Peng K
Fri Apr 01 00:00:00 EDT 2022
Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro.
Phytotherapy research : PTR
Mao J,Zhan H,Meng F,Wang G,Huang D,Liao Z,Chen M
Tue Mar 01 00:00:00 EST 2022
The Antigastric Cancer Effect of Triptolide is Associated With H19/NF-κB/FLIP Axis.
Frontiers in pharmacology
Yuan W,Huang J,Hou S,Li H,Bie L,Chen B,Li G,Zhou Y,Chen X
Sat Sep 17 00:00:00 EDT 2022
Usp8 promotes tumor cell migration through activating the JNK pathway.
Cell death & disease
Zhao Y,Peng D,Liu Y,Zhang Q,Liu B,Deng Y,Ding W,Zhou Z,Liu Q
Thu Mar 31 00:00:00 EDT 2022
Inflammation Induced by Lipopolysaccharide and Palmitic Acid Increases Cholesterol Accumulation via Enhancing Myeloid Differentiation Factor 88 Expression in HepG2 Cells.
Pharmaceuticals (Basel, Switzerland)
Chen J,Liu Y,Luo H,Chen G,Zheng Z,Wang T,Hu X,Zhao Y,Tang J,Su C,Zha L
Thu Jun 30 00:00:00 EDT 2022
MBD2 acts as a repressor to maintain the homeostasis of the Th1 program in type 1 diabetes by regulating the STAT1-IFN-γ axis.
Cell death and differentiation
Yue T,Sun F,Wang F,Yang C,Luo J,Rong S,Zhou H,Xiao J,Wang X,Zhou Q,Yang P,Zhang S,Li W,Xiong F,Yu Q,Wang CY
Sat Jan 01 00:00:00 EST 2022
Ferroptosis is induced by lenvatinib through fibroblast growth factor receptor-4 inhibition in hepatocellular carcinoma.
Cancer science
Iseda N,Itoh S,Toshida K,Tomiyama T,Morinaga A,Shimokawa M,Shimagaki T,Wang H,Kurihara T,Toshima T,Nagao Y,Harada N,Yoshizumi T,Mori M
Fri Jul 01 00:00:00 EDT 2022
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Biochemical pharmacology
Gu H,Li Y,Cui X,Cao H,Hou Z,Ti Y,Liu D,Gao J,Wang Y,Wen P
Sat Jan 01 00:00:00 EST 2022
Oncogenic TRIB2 interacts with and regulates PKM2 to promote aerobic glycolysis and lung cancer cell procession.
Cell death discovery
Liu YR,Song DD,Liang DM,Li YJ,Yan YF,Sun HF,Zhang ML,Hu JX,Zhao YL,Liang Y,Li YM,Yang Z,Wang RR,Zheng HF,Wang P,Xie SY
Tue Jul 05 00:00:00 EDT 2022
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Stem cell research & therapy
Yin BF,Li ZL,Yan ZQ,Guo Z,Liang JW,Wang Q,Zhao ZD,Li PL,Hao RC,Han MY,Li XT,Mao N,Ding L,Chen DF,Gao Y,Zhu H
Tue Jun 07 00:00:00 EDT 2022
Trans-anethole ameliorates LPS-induced inflammation via suppression of TLR4/NF-κB pathway in IEC-6 cells.
International immunopharmacology
Yu C,Wang D,Li Q,Tong Y,Yang Z,Wang T
Fri Jul 01 00:00:00 EDT 2022
Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.
Cell death discovery
Qiu P,Jie Y,Ma C,Chen H,Qin Y,Tu K,Wang L,Zhang Z
Tue Jun 07 00:00:00 EDT 2022
Ginsenoside Rc Modulates SIRT6-NRF2 Interaction to Alleviate Alcoholic Liver Disease.
Journal of agricultural and food chemistry
Pan Z,Guo J,Tang K,Chen Y,Gong X,Chen Y,Zhong Y,Xiao X,Duan S,Cui T,Wu X,Zhong Y,Yang X,Shen C,Gao Y
Wed Nov 09 00:00:00 EST 2022
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
International journal of biological sciences
Wu X,Wei S,Chen M,Li J,Wei Y,Zhang J,Dong W
Mon Aug 22 00:00:00 EDT 2022
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
In vitro cellular & developmental biology. Animal
Chen TY,Zheng SK
Sat Oct 01 00:00:00 EDT 2022
Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice.
Science advances
Sanz-Ros J,Romero-García N,Mas-Bargues C,Monleón D,Gordevicius J,Brooke RT,Dromant M,Díaz A,Derevyanko A,Guío-Carrión A,Román-Domínguez A,Inglés M,Blasco MA,Horvath S,Viña J,Borrás C
Fri Oct 21 00:00:00 EDT 2022
Panaxytriol upregulates CYP3A4 expression based on the interaction of PXR, CAR, HSP90α, and RXRα.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang L,Yan J,Liu J,Meng C,Liu F,Xia C
Fri Jul 01 00:00:00 EDT 2022
Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway.
Frontiers in pharmacology
Xu Z,Zhang M,Wang Y,Chen R,Xu S,Sun X,Yang Y,Lin Z,Wang S,Huang H
Sat Jul 16 00:00:00 EDT 2022
Trans-anethole ameliorates lipopolysaccharide-induced acute liver inflammation in broilers via inhibiting NF-κB signaling pathway.
Poultry science
Tong Y,Yu C,Xie Z,Zhang X,Yang Z,Wang T
Mon Aug 01 00:00:00 EDT 2022
Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer.
Acta pharmaceutica Sinica. B
Fan M,Gao J,Zhou L,Xue W,Wang Y,Chen J,Li W,Yu Y,Liu B,Shen Y,Xu Q
Thu Dec 01 00:00:00 EST 2022
TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
Frontiers in immunology
Shi B,Hao Y,Li W,Dong H,Xu M,Gao P
Thu May 19 00:00:00 EDT 2022
Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zheng CC,Liao L,Liu YP,Yang YM,He Y,Zhang GG,Li SJ,Liu T,Xu WW,Li B
Thu Dec 01 00:00:00 EST 2022
TERC suppresses PD-L1 expression by downregulating RNA binding protein HuR.
Science China. Life sciences
Jin H,Chen Y,Ren J,Huang J,Zhao Y,Liu H
Thu Dec 01 00:00:00 EST 2022
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression.
Experimental biology and medicine (Maywood, N.J.)
Zhang N,Liu S,Xu J,Ning T,Xie S,Min L,Zhu S,Zhang S,Zhu S
Thu Sep 01 00:00:00 EDT 2022
An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway.
International journal of molecular sciences
Yang J,Li J,Guo H,Zhang Y,Guo Z,Liu Y,Huo T
Thu May 19 00:00:00 EDT 2022
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen Y,Fan X,Qu Y,Tang M,Huang Y,Peng Y,Fu Q
Thu Sep 01 00:00:00 EDT 2022
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
European journal of medicinal chemistry
Guo J,Cheng M,Liu P,Cao D,Luo J,Wan Y,Fang Y,Jin Y,Xie SS,Liu J
Tue Nov 15 00:00:00 EST 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
International journal of molecular sciences
Cao Y,Zhang M,Li Y,Lu J,Zhou W,Li X,Shi H,Xu B,Li S
Tue Nov 22 00:00:00 EST 2022
CircSCAP interacts with SF3A3 to inhibit the malignance of non-small cell lung cancer by activating p53 signaling.
Journal of experimental & clinical cancer research : CR
Chen D,Zhou H,Cai Z,Cai K,Liu J,Wang W,Miao H,Li H,Li R,Li X,Chen Y,Wang HY,Wen Z
Fri Apr 01 00:00:00 EDT 2022
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells.
Cell death & disease
Chen L,Chen D,Li J,He L,Chen T,Song D,Shan S,Wang J,Lu X,Lu B
Mon Nov 28 00:00:00 EST 2022
Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.
European journal of medicinal chemistry
Tian C,Zhang G,Xia Z,Chen N,Yang S,Li L
Sat Mar 05 00:00:00 EST 2022
Puerarin ameliorates myocardial remodeling of spontaneously hypertensive rats through inhibiting TRPC6-CaN-NFATc3 pathway.
European journal of pharmacology
Yan J,Honglei Y,Yun W,Sheng D,Yun H,Anhua Z,Na F,Min L,Dandan S,Jing W,Junming T,Wenjun Z,Xiju H
Sat Oct 15 00:00:00 EDT 2022
ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
Journal of experimental & clinical cancer research : CR
Dong S,Liang S,Cheng Z,Zhang X,Luo L,Li L,Zhang W,Li S,Xu Q,Zhong M,Zhu J,Zhang G,Hu S
Sat Jan 08 00:00:00 EST 2022
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.
Biochimica et biophysica acta. Molecular cell research
Bai Z,Zhou Y,Ye X,Li Y,Peng Y,Guan Q,Zhang W,Ma L
Tue Feb 01 00:00:00 EST 2022
Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex.
Cell reports
Ohno SI,Oikawa K,Tsurui T,Harada Y,Ono K,Tateishi M,Mirza A,Takanashi M,Kanekura K,Nagase K,Shimada Y,Kudo Y,Ikeda N,Ochiya T,Wang X,Kuroda M
Tue Apr 12 00:00:00 EDT 2022
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
International journal of biological macromolecules
Zhang Y,Zhang X,Dai K,Zhu M,Liang Z,Pan J,Zhang Z,Xue R,Cao G,Hu X,Gong C
Sat Jan 01 00:00:00 EST 2022
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Environmental toxicology
Guan S,Zhang R,Zhao Y,Meng Z,Lu J
Sat Oct 01 00:00:00 EDT 2022
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.
Viruses
Zhao N,Wang F,Kong Z,Shang Y
Sat Jul 02 00:00:00 EDT 2022
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Journal of Zhejiang University. Science. B
Lu J,Fu S,Dai J,Hu J,Li S,Ji H,Wang Z,Yu J,Bao J,Xu B,Guo J,Yang H
Wed Jun 15 00:00:00 EDT 2022
Anti-Osteoclast Effect of Exportin-1 Inhibitor Eltanexor on Osteoporosis Depends on Nuclear Accumulation of IκBα-NF-κB p65 Complex.
Frontiers in pharmacology
Chen J,Song D,Xu Y,Wu L,Tang L,Su Y,Xie X,Zhao J,Xu J,Liu Q
Sat Sep 17 00:00:00 EDT 2022
Nuclear Fragility in Radiation-Induced Senescence: Blebs and Tubes Visualized by 3D Electron Microscopy.
Cells
Freyter BM,Abd Al-Razaq MA,Isermann A,Dietz A,Azimzadeh O,Hekking L,Gomolka M,Rübe CE
Thu Jan 13 00:00:00 EST 2022
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Cells & development
Zhang T,Liu X,Su K,Zheng Q,Liu P,Xu Z,Zhang Y
Tue Mar 01 00:00:00 EST 2022
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Bioengineered
Zhu W,Tang H,Li J,Guedes RM,Cao L,Guo C
Fri Apr 01 00:00:00 EDT 2022
TXNIP knockout improves cardiac function after myocardial infarction by promoting angiogenesis and reducing cardiomyocyte apoptosis.
Cardiovascular diagnosis and therapy
Wang J,Wang XJ,Zhang Y,Shi WJ,Lei ZD,Jiao XY
Wed Jun 01 00:00:00 EDT 2022
African swine fever virus pE301R negatively regulates cGAS-STING signaling pathway by inhibiting the nuclear translocation of IRF3.
Veterinary microbiology
Liu X,Liu H,Ye G,Xue M,Yu H,Feng C,Zhou Q,Liu X,Zhang L,Jiao S,Weng C,Huang L
Tue Nov 01 00:00:00 EDT 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 EDT 2022
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Frontiers in pharmacology
Li L,Deng S,Liu M,Yang M,Li J,Liu T,Zhang T,Zhao Y,He M,Wu D,Xu Y
Fri Dec 02 00:00:00 EST 2022
A dual Keap1 and p47phox inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Cell death & disease
Wang ZC,Niu KM,Wu YJ,Du KR,Qi LW,Zhou YB,Sun HJ
Mon Sep 26 00:00:00 EDT 2022
AKT2 reduces IFNβ1 production to modulate antiviral responses and systemic lupus erythematosus.
The EMBO journal
Zheng X,Xiao J,Jiang Q,Zheng L,Liu C,Dong C,Zheng Y,Ni P,Zhang C,Zhang F,Zhong R,Ding H,Wang Q,Qiu Y,Gao M,Ding J,Shen N,Wei B,Wang H
Tue Mar 15 00:00:00 EDT 2022
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Inflammation
Liu C,Li Y,Wang X
Mon Aug 01 00:00:00 EDT 2022
A polypeptide inhibitor of calcineurin blocks the calcineurin-NFAT signalling pathway in vivo and in vitro.
Journal of enzyme inhibition and medicinal chemistry
Wang P,Li W,Yang Y,Cheng N,Zhang Y,Zhang N,Yin Y,Tong L,Li Z,Luo J
Thu Dec 01 00:00:00 EST 2022
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Cellular and molecular gastroenterology and hepatology
Huang X,Yao Y,Hou X,Wei L,Rao Y,Su Y,Zheng G,Ruan XZ,Li D,Chen Y
Mon Jun 20 00:00:00 EDT 2022
CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment.
Molecular cancer
Pan Z,Xu T,Bao L,Hu X,Jin T,Chen J,Chen J,Qian Y,Lu X,Li L,Zheng G,Zhang Y,Zou X,Song F,Zheng C,Jiang L,Wang J,Tan Z,Huang P,Ge M
Mon Oct 03 00:00:00 EDT 2022
Silibinin relieves UVB-induced apoptosis of human skin cells by inhibiting the YAP-p73 pathway.
Acta pharmacologica Sinica
Liu WW,Wang F,Li C,Song XY,Otkur W,Zhu YY,Hayashi T,Mizuno K,Hattori S,Fujisaki H,Ikejima T
Mon Aug 01 00:00:00 EDT 2022
Neuroprotective Effects of Rhodiola Sacra on Transient Global Cerebral Ischemia Through Activating AMPK/Nrf2 Pathway in Rats.
Antioxidants & redox signaling
Li K,Jiang J,Shi Z,Zhan L,Peng L,Sun W,Tang Y,Zuo X,Xu E
Tue Mar 01 00:00:00 EST 2022
The pH sensor and ion binding of NhaD Na+ /H+ antiporter from IT superfamily.
Molecular microbiology
Lv P,Li Y,Wang R,Zhang Y,Wang W,Liu Y,Shang Y,Su D,Wang W,Yang C
Thu Sep 01 00:00:00 EDT 2022
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
eIF4A3 Promotes RNA Viruses' Replication by Inhibiting Innate Immune Responses.
Journal of virology
Gao Q,Jiang M,Zhao Y,Li G,Yang C,Ren C,Jin M,Chen H,Zhou H
Wed Nov 23 00:00:00 EST 2022
Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation.
Cell reports
Chen C,Zhang W,Zhou T,Liu Q,Han C,Huang Z,Chen S,Mei Q,Zhang C,Zhang K,Ma H,Zhou R,Jiang W,Pan W,Zhu S
Tue Nov 29 00:00:00 EST 2022
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Nature communications
Yang R,Yang C,Ma L,Zhao Y,Guo Z,Niu J,Chu Q,Ma Y,Li B
Thu Nov 17 00:00:00 EST 2022
TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation.
Genome research
Xu W,Liu C,Deng B,Lin P,Sun Z,Liu A,Xuan J,Li Y,Zhou K,Zhang X,Huang Q,Zhou H,He Q,Li B,Qu L,Yang J
Wed Jun 01 00:00:00 EDT 2022
TRIM32 Inhibition Attenuates Apoptosis, Oxidative Stress, and Inflammatory Injury in Podocytes Induced by High Glucose by Modulating the Akt/GSK-3β/Nrf2 Pathway.
Inflammation
Chen Z,Tian L,Wang L,Ma X,Lei F,Chen X,Fu R
Wed Jun 01 00:00:00 EDT 2022
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Frontiers in oncology
Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P
Sat May 07 00:00:00 EDT 2022
African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.
Journal of virology
Li L,Fu J,Li J,Guo S,Chen Q,Zhang Y,Liu Z,Tan C,Chen H,Wang X
Wed Sep 14 00:00:00 EDT 2022
Dopamine inhibits the expression of proinflammatory cytokines of microglial cells through the formation of dopamine quinone in the mouse striatum.
Journal of pharmacological sciences
Yoshioka Y,Sugino Y,Yamamuro A,Ishimaru Y,Maeda S
Sat Jan 01 00:00:00 EST 2022
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4-MAPK-NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation.
Inflammation
Chen Q,Lu H,Duan C,Zhu X,Zhang Y,Li M,Zhang D
Tue Feb 01 00:00:00 EST 2022
Exposure of mouse oocytes to N,N-dimethylformamide impairs mitochondrial functions and reduces oocyte quality.
Environmental toxicology
Fei CF,Guo SM,Yin Y,He X,Zhou LQ
Fri Jul 01 00:00:00 EDT 2022
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Ecotoxicology and environmental safety
Zhou X,Zhang X,Zhou X,Abulimiti G,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Yang J,Song N
Thu Dec 01 00:00:00 EST 2022
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Journal of animal science and biotechnology
Chen Y,Zhang H,Li Y,Ji S,Jia P,Wang T
Fri Nov 04 00:00:00 EDT 2022
Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity.
Cell death & disease
Hu G,Chen Y,Yang X,Wang Y,He J,Wang T,Fan Q,Deng L,Tu J,Tan H,Cheng J
Fri Jul 22 00:00:00 EDT 2022
A multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress.
Nature communications
Griffin WC,McKinzey DR,Klinzing KN,Baratam R,Eliyapura A,Trakselis MA
Tue Aug 30 00:00:00 EDT 2022
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Bioorganic chemistry
Gong X,He Y,Yang D,Yang S,Li J,Zhao H,Chen Q,Ren Q,Zhang B
Sat Oct 01 00:00:00 EDT 2022
Regulation of TET2 gene expression and 5mC oxidation in breast cancer cells by estrogen signaling.
Biochemical and biophysical research communications
Zhu X,Xiong L,Lyu R,Shen Y,Liu L,Li S,Argueta C,Tan L
Sat Jan 22 00:00:00 EST 2022
RFWD3 and translesion DNA polymerases contribute to PCNA modification-dependent DNA damage tolerance.
Life science alliance
Kanao R,Kawai H,Taniguchi T,Takata M,Masutani C
Fri Jul 29 00:00:00 EDT 2022
Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Modulate miRNA Biogenesis through Aberrant Interactions with Exportin 5.
ACS chemical biology
Chen X,He X,Yang YY,Wang Y
Fri Dec 16 00:00:00 EST 2022
PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer.
Experimental & molecular medicine
Ma H,Qi G,Han F,Peng J,Yuan C,Kong B
Fri Jul 01 00:00:00 EDT 2022
Endocytosis triggers V-ATPase-SYK-mediated priming of cGAS activation and innate immune response.
Proceedings of the National Academy of Sciences of the United States of America
Yang YL,Cao LB,He WR,Zhong L,Guo Y,Yang Q,Shu HB,Hu MM
Tue Oct 25 00:00:00 EDT 2022
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Stem cell research & therapy
Jin C,Ou Q,Chen J,Wang T,Zhang J,Wang Z,Wang Y,Tian H,Xu JY,Gao F,Wang J,Li J,Lu L,Xu GT
Fri Apr 01 00:00:00 EDT 2022
The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers.
Nature communications
Zhang Y,Ma Z,Li C,Wang C,Jiang W,Chang J,Han S,Lu Z,Shao Z,Wang Y,Wang H,Jiao C,Wang D,Wu X,Shen H,Wang X,Hu Z,Li X
Wed Jun 01 00:00:00 EDT 2022
Fusobacterium nucleatum reduces METTL3-mediated m6A modification and contributes to colorectal cancer metastasis.
Nature communications
Chen S,Zhang L,Li M,Zhang Y,Sun M,Wang L,Lin J,Cui Y,Chen Q,Jin C,Li X,Wang B,Chen H,Zhou T,Wang L,Hsu CH,Zhuo W
Thu Mar 10 00:00:00 EST 2022
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Journal of cellular physiology
Guo J,Nie J,Chen Z,Wang X,Hu H,Xu J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Oct 01 00:00:00 EDT 2022
Very-low-density lipoprotein receptor-enhanced lipid metabolism in pancreatic stellate cells promotes pancreatic fibrosis.
Immunity
Yang X,Chen J,Wang J,Ma S,Feng W,Wu Z,Guo Y,Zhou H,Mi W,Chen W,Yin B,Lin Y
Tue Jul 12 00:00:00 EDT 2022
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Frontiers in pharmacology
Liu M,Peng Y,Che Y,Zhou M,Bai Y,Tang W,Huang S,Zhang B,Deng S,Wang C,Yu Z
Tue Sep 13 00:00:00 EDT 2022
O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation.
Journal of advanced research
Zhang H,Qi J,Pei J,Zhang M,Shang Y,Li Z,Wang Y,Guo J,Sun K,Fan J,Sui L,Xu Y,Kong L,Kong Y
Tue Mar 01 00:00:00 EST 2022
Cysteine dioxygenase 1 attenuates the proliferation via inducing oxidative stress and integrated stress response in gastric cancer cells.
Cell death discovery
Ma G,Zhao Z,Qu Y,Cai F,Liu S,Liang H,Zhang R,Deng J
Fri Dec 16 00:00:00 EST 2022
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
Environmental toxicology
Jin X,Yu W,Ye P
Fri Apr 01 00:00:00 EDT 2022
Polysaccharide extract from Isatidis Radix inhibits multiple inflammasomes activation and alleviate gouty arthritis.
Phytotherapy research : PTR
Ren L,Li Q,Li H,Zhan X,Yang R,Li Z,Fang Z,Liu T,Wei Z,Zhao J,Lin L,Mou W,Dai W,Bai Z,Xu G,Cao J
Mon Aug 01 00:00:00 EDT 2022
KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy.
Experimental and therapeutic medicine
Tan Z,Ren H,Liu Y,Yang H,Luo Q,Deng X
Thu Dec 01 00:00:00 EST 2022
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Lu Z,Huang L,Li Y,Xu Y,Zhang R,Zhou Q,Sun Q,Lu Y,Chen J,Shen Y,Li J,Zhao B
Sat Jan 01 00:00:00 EST 2022
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Frontiers in medicine
Wang D,Yin L,Chen R,Tan W,Liang L,Xiang J,Zhang H,Zhou X,Deng H,Guo B,Wang Y
Sat Feb 11 00:00:00 EST 2023
splitSMLM, a spectral demixing method for high-precision multi-color localization microscopy applied to nuclear pore complexes.
Communications biology
Andronov L,Genthial R,Hentsch D,Klaholz BP
Mon Oct 17 00:00:00 EDT 2022
Oleanolic acid alleviates ANIT-induced cholestatic liver injury by activating Fxr and Nrf2 pathways to ameliorate disordered bile acids homeostasis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu J,Liu J,Meng C,Huang C,Liu F,Xia C
Wed Jul 20 00:00:00 EDT 2022
Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways.
Journal of food biochemistry
Ma Y,Xiang S,Jiang W,Kong L,Tan Z,Liang Z,Yuan Z,Yi J,Zhu L
Fri Jul 01 00:00:00 EDT 2022
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease.
Acta pharmacologica Sinica
Wang XJ,Qi L,Cheng YF,Ji XF,Chi TY,Liu P,Zou LB
Mon Aug 01 00:00:00 EDT 2022
Bergamottin promotes osteoblast differentiation and bone formation via activating the Wnt/β-catenin signaling pathway.
Food & function
Wang X,Tian Y,Liang X,Yin C,Huai Y,Zhao Y,Huang Q,Chu X,Wang W,Qian A
Mon Mar 07 00:00:00 EST 2022
Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.
International journal of molecular sciences
Shi K,Xiao Y,Dong Y,Wang D,Xie Y,Tu J,Xu K,Zhou Z,Cao G,Liu Y
Sat Dec 17 00:00:00 EST 2022
Nrf2 Deficiency Exacerbated CLP-Induced Pulmonary Injury and Inflammation through Autophagy- and NF-κB/PPARγ-Mediated Macrophage Polarization.
Cells
Luo J,Wang J,Zhang J,Sang A,Ye X,Cheng Z,Li X
Sun Dec 04 00:00:00 EST 2022
Blocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization.
Cell death & disease
Liu H,Zhao D,Li H,Zhang W,Lin Q,Wang X,Zheng S,Zhang L,Li L,Hu S,Hu Y
Mon Feb 21 00:00:00 EST 2022
HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury.
eLife
Woods PS,Kimmig LM,Sun KA,Meliton AY,Shamaa OR,Tian Y,Cetin-Atalay R,Sharp WW,Hamanaka RB,Mutlu GM
Wed Jul 13 00:00:00 EDT 2022
AMOTL2 restrains transforming growth factor-β1-induced proliferation and extracellular matrix deposition of airway smooth muscle cells via the down-regulation of YAP1 activation.
Environmental toxicology
Fang P,Deng WJ,Fan N,Shi J,Shi HY,Ou L,Pan JL,Yang SY
Mon Nov 01 00:00:00 EDT 2021
LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior.
eLife
Naetar N,Georgiou K,Knapp C,Bronshtein I,Zier E,Fichtinger P,Dechat T,Garini Y,Foisner R
Fri Feb 19 00:00:00 EST 2021
Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Journal of physiology and biochemistry
Li Y,Zhao Y,Li Y,Zhang X,Li C,Long N,Chen X,Bao L,Zhou J,Xie Y
Mon Feb 01 00:00:00 EST 2021
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Journal of agricultural and food chemistry
Zhao Y,Lu J,Mao A,Zhang R,Guan S
Wed Aug 25 00:00:00 EDT 2021
Salubrinal Alleviates Collagen-Induced Arthritis through Promoting P65 Degradation in Osteoclastogenesis.
International journal of molecular sciences
Wang Z,Li Z,Wang G,Sun Y,Yuan Y,Nie H
Sun Mar 28 00:00:00 EDT 2021
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Journal of inflammation research
Wang H,Jiang Z,Pang Z,Qi G,Hua B,Yan Z,Yuan H
Thu Apr 21 00:00:00 EDT 2022
CLIC1 Inhibition Protects Against Cellular Senescence and Endothelial Dysfunction Via the Nrf2/HO-1 Pathway.
Cell biochemistry and biophysics
Lu D,Le Y,Ding J,Dou X,Mao W,Zhu J
Tue Jun 01 00:00:00 EDT 2021
ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L.
Cell death & disease
Zhang W,Zhang R,Zeng Y,Li Y,Chen Y,Zhou J,Zhang Y,Wang A,Zhu J,Liu Z,Yan Z,Huang JA
Sat Jul 31 00:00:00 EDT 2021
MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm.
Cell death and differentiation
Hu L,Yin C,Chen D,Wu Z,Liang S,Zhang Y,Huang Z,Liu S,Xu X,Chen Z,Zhang Y,Qian A
Thu Jul 01 00:00:00 EDT 2021
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
Steroids
Xu J,Wang Y,Wang Z,Wang Y,He X
Tue Jun 01 00:00:00 EDT 2021
Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model.
Naunyn-Schmiedeberg's archives of pharmacology
Xu H,Qi Q,Yan X
Fri Jan 01 00:00:00 EST 2021
Loss of PHLDA1 has a protective role in OGD/R-injured neurons via regulation of the GSK-3β/Nrf2 pathway.
Human & experimental toxicology
Yang F,Chen R
Mon Nov 01 00:00:00 EDT 2021
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression.
Nature communications
Li X,Yuan B,Lu M,Wang Y,Ding N,Liu C,Gao M,Yao Z,Zhang S,Zhao Y,Xie L,Chen Z
Fri Dec 10 00:00:00 EST 2021
Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways.
Development (Cambridge, England)
Okubo Y,Ohtake F,Igarashi K,Yasuhiko Y,Hirabayashi Y,Saga Y,Kanno J
Fri Oct 01 00:00:00 EDT 2021
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway.
Cell death and differentiation
Du W,Zhu J,Zeng Y,Liu T,Zhang Y,Cai T,Fu Y,Zhang W,Zhang R,Liu Z,Huang JA
Thu Apr 01 00:00:00 EDT 2021
Establishment of a GFP::LMNB1 knockin cell line (CSUi002-A-1) from a dystonia patient-specific iPSC by CRISPR/Cas9 editing.
Stem cell research
Tang Y,Ren J,Li CC
Sun Aug 01 00:00:00 EDT 2021
Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: A role for the integrated stress response.
Glia
Roth LM,Zidane B,Festa L,Putatunda R,Romer M,Monnerie H,Jordan-Sciutto KL,Grinspan JB
Mon Feb 01 00:00:00 EST 2021
Short-term standard alcohol consumption enhances platelet response to clopidogrel through inhibition of Nrf2/Ces1 pathway and induction of Cyp2c in mice.
Life sciences
Ge PX,Jiang LP,Tai T,Zhu T,Ji JZ,Li YF,Mi QY,Xie HG
Sun Aug 15 00:00:00 EDT 2021
5-Azacytidine Transiently Restores Dysregulated Erythroid Differentiation Gene Expression in TET2-Deficient Erythroleukemia Cells.
Molecular cancer research : MCR
Reilly BM,Luger T,Park S,Lio CJ,González-Avalos E,Wheeler EC,Lee M,Williamson L,Tanaka T,Diep D,Zhang K,Huang Y,Rao A,Bejar R
Mon Mar 01 00:00:00 EST 2021
Resveratrol ameliorates sevoflurane-induced cognitive impairment by activating the SIRT1/NF-κB pathway in neonatal mice.
The Journal of nutritional biochemistry
Tang XL,Wang X,Fang G,Zhao YL,Yan J,Zhou Z,Sun R,Luo AL,Li SY
Thu Apr 01 00:00:00 EDT 2021
G-Quadruplexes Formation at the Upstream Region of Replication Origin (OriL) of the Pseudorabies Virus: Implications for Antiviral Targets.
Viruses
Zhu Y,Liu W,Zhang C
Thu Nov 04 00:00:00 EDT 2021
HDAC6 Negatively Regulates miR-155-5p Expression to Elicit Proliferation by Targeting RHEB in Microvascular Endothelial Cells under Mechanical Unloading.
International journal of molecular sciences
Xu L,Zhang L,Zhang X,Li G,Wang Y,Dong J,Wang H,Hu Z,Cao X,Zhang S,Shi F
Wed Sep 29 00:00:00 EDT 2021
Cynandione A causes a dynamic change in SIRT1 nuclear trafficking via PKA signaling and beige adipocyte differentiation in 3T3-L1 cells.
European journal of pharmacology
Sawamoto A,Kanazaki A,Nakanishi M,Amakura Y,Yoshimura M,Uchiyama N,Hakamatsuka T,Okuyama S,Nakajima M
Fri Oct 15 00:00:00 EDT 2021
Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives.
Journal of cellular and molecular medicine
Li X,Wang X,Miao L,Liu Y,Lin X,Guo Y,Yuan R,Tian H
Tue Jun 01 00:00:00 EDT 2021
Early-senescent bone marrow mesenchymal stem cells promote C2C12 cell myogenic differentiation by preventing the nuclear translocation of FOXO3.
Life sciences
Che J,Xu C,Wu Y,Jia P,Han Q,Ma Y,Wang X,Du Y,Zheng Y
Thu Jul 15 00:00:00 EDT 2021
A quinazoline-based bromodomain inhibitor, CN210, ameliorates indomethacin-induced ileitis in mice by inhibiting inflammatory cytokine expression.
Drug development research
Noguchi T,Hidaka K,Kobayashi S,Matsumoto K,Yoshioka M,Hu X,Maloney DJ,Yang SM,Kato S
Wed Dec 01 00:00:00 EST 2021
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Kong L,Dong R,Huang K,Wang X,Wang D,Yue N,Wang C,Sun P,Gu J,Luo H,Liu K,Wu J,Sun H,Meng Q
Wed Sep 01 00:00:00 EDT 2021
Role of Glycated High Mobility Group Box-1 in Gastric Cancer.
International journal of molecular sciences
Kishi S,Nishiguchi Y,Honoki K,Mori S,Fujiwara-Tani R,Sasaki T,Fujii K,Kawahara I,Goto K,Nakashima C,Kido A,Tanaka Y,Luo Y,Kuniyasu H
Thu May 13 00:00:00 EDT 2021
Myricetin protects against H2 O2 -induced oxidative damage and apoptosis in bovine mammary epithelial cells.
Journal of cellular physiology
Kan X,Liu J,Chen Y,Guo W,Xu D,Cheng J,Cao Y,Yang Z,Fu S
Thu Apr 01 00:00:00 EDT 2021
Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus.
Cell death and differentiation
Chen L,Zhang J,Zou Y,Wang F,Li J,Sun F,Luo X,Zhang M,Guo Y,Yu Q,Yang P,Zhou Q,Chen Z,Zhang H,Gong Q,Zhao J,Eizirik DL,Zhou Z,Xiong F,Zhang S,Wang CY
Tue Jun 01 00:00:00 EDT 2021
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Chinese medicine
Zhang C,Li Q,Qin G,Zhang Y,Li C,Han L,Wang R,Wang S,Chen H,Liu K,He C
Mon May 31 00:00:00 EDT 2021
Nicotinamide improves NAD+ levels to protect against acetaminophen-induced acute liver injury in mice.
Human & experimental toxicology
Xu J,Zhang L,Jiang R,Hu K,Hu D,Liao C,Jiang S,Yang Y,Huang J,Tang L,Li L
Mon Nov 01 00:00:00 EDT 2021
Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening.
Nature communications
Baxley RM,Leung W,Schmit MM,Matson JP,Yin L,Oram MK,Wang L,Taylor J,Hedberg J,Rogers CB,Harvey AJ,Basu D,Taylor JC,Pagnamenta AT,Dreau H,Craft J,Ormondroyd E,Watkins H,Hendrickson EA,Mace EM,Orange JS,Aihara H,Stewart GS,Blair E,Cook JG,Bielinsky AK
Fri Mar 12 00:00:00 EST 2021
Upregulation of UGT1A1 expression by ursolic acid and oleanolic acid via the inhibition of the PKC/NF-κB signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yuan L,Zhang L,Yao N,Wu L,Liu J,Liu F,Zhang H,Hu X,Xiong Y,Xia C
Mon Nov 01 00:00:00 EDT 2021
ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD.
Nucleic acids research
Park J,Lee J,Kim JH,Lee J,Park H,Lim C
Mon Nov 08 00:00:00 EST 2021
Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J,Li D
Mon May 17 00:00:00 EDT 2021
C1q/TNF-related protein 4 restores leptin sensitivity by downregulating NF-κB signaling and microglial activation.
Journal of neuroinflammation
Ye L,Jia G,Li Y,Wang Y,Chen H,Yu L,Wu D
Sun Jul 18 00:00:00 EDT 2021
Repeated neonatal sevoflurane induced neurocognitive impairment through NF-κB-mediated pyroptosis.
Journal of neuroinflammation
Dai J,Li X,Wang C,Gu S,Dai L,Zhang J,Fan Y,Wu J
Sat Aug 21 00:00:00 EDT 2021
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Journal of receptor and signal transduction research
Ma X,Zhang J,Wu Z,Wang X
Sun Aug 01 00:00:00 EDT 2021
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Nature communications
Shi W,Zhang G,Ma Z,Li L,Liu M,Qin L,Yu Z,Zhao L,Liu Y,Zhang X,Qin J,Ye H,Jiang X,Zhou H,Sun H,Jiao Z
Fri May 14 00:00:00 EDT 2021
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Cao YY,Wang ZH,Xu QC,Chen Q,Wang Z,Lu WH
Thu Jul 01 00:00:00 EDT 2021
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Cell communication and signaling : CCS
Li J,Wang S,Wang N,Zheng Y,Yang B,Wang X,Zhang J,Pan B,Wang Z
Mon Aug 30 00:00:00 EDT 2021
SNX25 regulates proinflammatory cytokine expression via the NF-κB signal in macrophages.
PloS one
Nishimura K,Tanaka T,Takemura S,Tatsumi K,Wanaka A
Tue Oct 12 00:00:00 EDT 2021
Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors.
Journal of photochemistry and photobiology. B, Biology
Liu W,Wang F,Li C,Otkur W,Hayashi T,Mizuno K,Hattori S,Fujisaki H,Onodera S,Ikejima T
Mon Mar 01 00:00:00 EST 2021
Inhibition of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model.
Cancer gene therapy
Tanigawa S,Fujita M,Moyama C,Ando S,Ii H,Kojima Y,Fujishita T,Aoki M,Takeuchi H,Yamanaka T,Takahashi Y,Hashimoto N,Nakata S
Wed Dec 01 00:00:00 EST 2021
An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo.
Nature aging
Wang B,Wang L,Gasek NS,Zhou Y,Kim T,Guo C,Jellison ER,Haynes L,Yadav S,Tchkonia T,Kuchel GA,Kirkland JL,Xu M
Fri Oct 01 00:00:00 EDT 2021
Particulate matter promotes hyperpigmentation via AhR/MAPK signaling activation and by increasing α-MSH paracrine levels in keratinocytes.
Environmental pollution (Barking, Essex : 1987)
Shi Y,Zeng Z,Liu J,Pi Z,Zou P,Deng Q,Ma X,Qiao F,Xiong W,Zhou C,Zeng Q,Xiao R
Tue Jun 01 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Human & experimental toxicology
Liu X,Li M,Zhu J,Huang W,Song J
Thu Jul 01 00:00:00 EDT 2021
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Science advances
Cao P,Yang A,Li P,Xia X,Han Y,Zhou G,Wang R,Yang F,Li Y,Zhang Y,Cui Y,Ji H,Lu L,He F,Zhou G
Sun Aug 01 00:00:00 EDT 2021
HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.
PloS one
Qiao J,Peng Q,Qian F,You Q,Feng L,Hu S,Liu W,Huang L,Shu X,Sun B
Mon Jan 17 00:00:00 EST 2022
Fenofibrate inhibits TGF-β-induced myofibroblast differentiation and activation in human lung fibroblasts in vitro.
FEBS open bio
Kikuchi R,Maeda Y,Tsuji T,Yamaguchi K,Abe S,Nakamura H,Aoshiba K
Sun Aug 01 00:00:00 EDT 2021
UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma.
Journal of translational medicine
Zhu J,Ao H,Liu M,Cao K,Ma J
Mon Aug 30 00:00:00 EDT 2021
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Frontiers in cell and developmental biology
Xi X,Li Z,Liu H,Chen S,Liu D
Tue Jan 25 00:00:00 EST 2022
Activation of AMPK inhibits Galectin-3-induced pulmonary artery smooth muscle cells proliferation by upregulating hippo signaling effector YAP.
Molecular and cellular biochemistry
Zhang Q,Li W,Zhu Y,Wang Q,Zhai C,Shi W,Feng W,Wang J,Yan X,Chai L,Chen Y,Li C,Liu P,Li M
Sun Aug 01 00:00:00 EDT 2021
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Frontiers in pharmacology
Jiang J,Dong C,Zhai L,Lou J,Jin J,Cheng S,Chen Z,Guo X,Lin D,Ding J,Gao W
Tue Nov 23 00:00:00 EST 2021
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Frontiers in pharmacology
Jiang J,Dong C,Zhai L,Lou J,Jin J,Cheng S,Chen Z,Guo X,Lin D,Ding J,Gao W
Tue Nov 23 00:00:00 EST 2021
Chromothripsis drives the evolution of gene amplification in cancer.
Nature
Shoshani O,Brunner SF,Yaeger R,Ly P,Nechemia-Arbely Y,Kim DH,Fang R,Castillon GA,Yu M,Li JSZ,Sun Y,Ellisman MH,Ren B,Campbell PJ,Cleveland DW
Mon Mar 01 00:00:00 EST 2021
Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-β42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-κB Signaling.
Frontiers in neuroscience
Fu Y,Jia J
Wed Apr 20 00:00:00 EDT 2022
Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.
Biochemical and biophysical research communications
Feng J,Xie L,Yu X,Liu C,Dong H,Lu W,Kong R
Fri Mar 12 00:00:00 EST 2021
6-Gingerol attenuates ventilator-induced lung injury via anti-inflammation and antioxidative stress by modulating the PPARγ/NF-κBsignalling pathway in rats.
International immunopharmacology
Hong W,Zhi FX,Kun TH,Hua FJ,Huan Ling L,Fang F,Wen C,Jie W,Yang LC
Mon Mar 01 00:00:00 EST 2021
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
Oxidative medicine and cellular longevity
Li X,Wang X,Miao L,Guo Y,Yuan R,Ren J,Huang Y,Tian H
Fri Jan 28 00:00:00 EST 2022
Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment.
The Journal of biological chemistry
McKinzey DR,Gomathinayagam S,Griffin WC,Klinzing KN,Jeffries EP,Rajkovic A,Trakselis MA
Tue Aug 24 00:00:00 EDT 2021
Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling.
Nature communications
Guo G,Gao M,Gao X,Zhu B,Huang J,Tu X,Kim W,Zhao F,Zhou Q,Zhu S,Wu Z,Yan Y,Zhang Y,Zeng X,Zhu Q,Yin P,Luo K,Sun J,Deng M,Lou Z
Mon Apr 12 00:00:00 EDT 2021
Human Cytomegalovirus Interactions with the Basement Membrane Protein Nidogen 1.
Journal of virology
Kuan MI,Jaeger HK,Balemba OB,O'Dowd JM,Duricka D,Hannemann H,Marx E,Teissier N,Gabrielli L,Bonasoni MP,Keithley EM,Fortunato EA
Wed Jan 13 00:00:00 EST 2021
TLR5 Supports Development of Placental Labyrinthine Zone in Mice.
Frontiers in cell and developmental biology
Yiu JHC,Cheung SWM,Cai J,Chan KS,Chen J,Cheong LY,Chau HT,Xu A,Li RHW,Woo CW
Tue Aug 17 00:00:00 EDT 2021
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
International immunopharmacology
Cao YY,Wang Z,Wang ZH,Jiang XG,Lu WH
Fri Jan 01 00:00:00 EST 2021
Melatonin Ameliorates Lipopolysaccharide-Induced Microglial Inflammation via Triggering SIRT1/HMGB1 Signaling Axis.
Journal of molecular neuroscience : MN
Chibaatar E,Le K,Abdoulaye IA,Wu S,Guo Y
Thu Apr 01 00:00:00 EDT 2021
Localization of the WD repeat-containing protein 5 to the Virion Assembly Compartment Facilitates Human Cytomegalovirus Assembly.
Journal of virology
Yang B,Yao Y,Wu H,Yang H,Ma XH,Li D,Wang XZ,Huang SN,Jiang X,Cheng S,Sun JY,Huang ZL,Zhao C,McVoy MA,Ahn JH,Zeng WB,Britt WJ,Gong S,Luo MH
Thu Mar 25 00:00:00 EDT 2021
RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.
PLoS genetics
Kim JI,Nakahama T,Yamasaki R,Costa Cruz PH,Vongpipatana T,Inoue M,Kanou N,Xing Y,Todo H,Shibuya T,Kato Y,Kawahara Y
Sat May 01 00:00:00 EDT 2021
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation.
Toxicology
Shao Y,Wang X,Zhou Y,Jiang Y,Wu R,Lu C
Wed Sep 01 00:00:00 EDT 2021
4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response.
Frontiers in pharmacology
Li R,Yang W,Yin Y,Ma X,Zhang P,Tao K
Sat Jun 12 00:00:00 EDT 2021
RNF128 suppresses the malignancy of colorectal cancer cells via inhibition of Wnt/β-catenin signaling.
American journal of translational research
Zhu Y,Gan Y,Zou R,Sha H,Lu Y,Zhang Y,Feng J
Tue Jan 18 00:00:00 EST 2022
Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin.
Chemosphere
Qin Q,Yang B,Liu Z,Xu L,Song E,Song Y
Fri Jan 01 00:00:00 EST 2021
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Journal of agricultural and food chemistry
Xing Y,Ren X,Li X,Sui L,Shi X,Sun Y,Quan C,Xiu Z,Dong Y
Wed Sep 01 00:00:00 EDT 2021
Thymus quinquecostatus Celak. ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: Activating Keap1/Nrf2/HO-1 signaling pathway and directly scavenging ROS.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fan S,Liu X,Wang Y,Ren X,Liu Y,Dong Y,Fan Q,Wei J,Ma J,Yu A,Song R,Sui H,Shen M,Fang F,Xia Q,She G
Fri Oct 01 00:00:00 EDT 2021
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
Cell research
Wu J,Wu C,Xing F,Cao L,Zeng W,Guo L,Li P,Zhong Y,Jiang H,Luo M,Shi G,Bu L,Ji Y,Hou P,Peng H,Huang J,Li C,Guo D
Wed Sep 01 00:00:00 EDT 2021
Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner.
Cell death & disease
Zhang W,Yin G,Zhao H,Ling H,Xie Z,Xiao C,Chen Y,Lin Y,Jiang T,Jin S,Wang J,Yang X
Wed Jan 20 00:00:00 EST 2021
Activation of yes-associated protein mediates sphingosine-1-phosphate-induced proliferation and migration of pulmonary artery smooth muscle cells and its potential mechanisms.
Journal of cellular physiology
Shi W,Wang Q,Wang J,Yan X,Feng W,Zhang Q,Zhai C,Chai L,Li S,Xie X,Li M
Tue Jun 01 00:00:00 EDT 2021
P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a.
Biochemical pharmacology
Ji JZ,Li YF,Jiang LP,Tai T,Ge PX,Mi QY,Zhu T,Xie HG
Fri Jan 01 00:00:00 EST 2021
Pseudoginsenoside F11 ameliorates the dysfunction of the autophagy-lysosomal pathway by activating calcineurin-mediated TFEB nuclear translocation in neuron during permanent cerebral ischemia.
Experimental neurology
Fu X,Liu Y,Zhang H,Yu X,Wang X,Wu C,Yang J
Thu Apr 01 00:00:00 EDT 2021
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Life sciences
Yang W,Liu J,Hou L,Chen Q,Liu Y
Fri Jan 15 00:00:00 EST 2021
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li X,Liu X,Deng R,Gao S,Jiang Q,Liu R,Li H,Miao Y,Zhai Y,Zhang S,Wang Z,Ren Y,Ning W,Zhou H,Yang C
Fri Jan 01 00:00:00 EST 2021
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
International immunopharmacology
Wen L,Yang QH,Ma XL,Li T,Xiao S,Sun CF
Fri Oct 01 00:00:00 EDT 2021
Caveolin-1 Alleviates Acetaminophen-Induced Fat Accumulation in Non-Alcoholic Fatty Liver Disease by Enhancing Hepatic Antioxidant Ability via Activating AMPK Pathway.
Frontiers in pharmacology
Wang J,Jiang W,Xin J,Xue W,Shi C,Wen J,Huang Y,Hu C
Tue Jul 27 00:00:00 EDT 2021
Iguratimod inhibits osteoclastogenesis by modulating the RANKL and TNF-α signaling pathways.
International immunopharmacology
Li CH,Ma ZZ,Jian LL,Wang XY,Sun L,Liu XY,Yao ZQ,Zhao JX
Fri Jan 01 00:00:00 EST 2021
PKM2 Is the Target of a Multi-Herb-Combined Decoction During the Inhibition of Gastric Cancer Progression.
Frontiers in oncology
Sun Q,Yuan M,Wang H,Zhang X,Zhang R,Wang H,Chen X,Zhu M,Liu S,Wu J
Fri Apr 29 00:00:00 EDT 2022
TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma.
Frontiers in oncology
Bao S,Jiang X,Jin S,Tu P,Lu J
Tue Jul 13 00:00:00 EDT 2021
Iron-bearing nanoparticles trigger human umbilical vein endothelial cells ferroptotic responses by promoting intracellular iron level.
Environmental pollution (Barking, Essex : 1987)
Liu Z,Xia X,Lv X,Song E,Song Y
Fri Oct 15 00:00:00 EDT 2021
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Cancer communications (London, England)
Liu X,Chen D,Chen H,Wang W,Liu Y,Wang Y,Duan C,Ning Z,Guo X,Otkur W,Liu J,Qi H,Liu X,Lin A,Xia T,Liu HX,Piao HL
Thu Jul 01 00:00:00 EDT 2021
Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis.
Osteoarthritis and cartilage
Shao Z,Wang B,Shi Y,Xie C,Huang C,Chen B,Zhang H,Zeng G,Liang H,Wu Y,Zhou Y,Tian N,Wu A,Gao W,Wang X,Zhang X
Mon Mar 01 00:00:00 EST 2021
AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation.
Frontiers in pharmacology
Kong L,Zhang H,Lu C,Shi K,Huang H,Zheng Y,Wang Y,Wang D,Wang H,Huang W
Sat Sep 18 00:00:00 EDT 2021
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
Cell and tissue research
Cui Q,Yan L
Mon Nov 01 00:00:00 EDT 2021
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
International immunopharmacology
Zhang L,Zhu T,He F,Li X
Wed Dec 01 00:00:00 EST 2021
ATF3 drives senescence by reconstructing accessible chromatin profiles.
Aging cell
Zhang C,Zhang X,Huang L,Guan Y,Huang X,Tian XL,Zhang L,Tao W
Mon Mar 01 00:00:00 EST 2021
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
International immunopharmacology
Hu S,Li Y,Wang B,Peng K
Fri Oct 01 00:00:00 EDT 2021
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
International journal of biological macromolecules
Zong X,Xiao X,Kai L,Cheng Y,Fu J,Xu W,Wang Y,Zhao K,Jin M
Fri Jan 15 00:00:00 EST 2021
miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.
Biochemical pharmacology
Han S,Wang Z,Liu J,Wang HD,Yuan Q
Tue Jun 01 00:00:00 EDT 2021
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Foods (Basel, Switzerland)
Zhang J,Ma X,Fan D
Wed May 26 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
Polyphenols from Penthorum chinense Pursh. Attenuates high glucose-induced vascular inflammation through directly interacting with Keap1 protein.
Journal of ethnopharmacology
Sun Y,He L,Wang W,Wang T,Hua W,Li T,Wang L,Gao T,Chen F,Tang L
Thu Mar 25 00:00:00 EDT 2021
α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.
Bioengineered
Zhang S,Wang J,Chen T,Wang J,Wang Y,Yu Z,Zhao K,Zheng K,Chen Y,Wang Z,Li B,Wang C,Huang W,Fu Z,Chen J
Wed Dec 01 00:00:00 EST 2021
Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson's Disease Rats.
Frontiers in pharmacology
Zhou L,Zheng LF,Zhang XL,Wang ZY,Yao YS,Xiu XL,Liu CZ,Zhang Y,Feng XY,Zhu JX
Sat Dec 11 00:00:00 EST 2021
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
The EMBO journal
Duan S,Li H,Zhang Y,Yang S,Chen Y,Qiu B,Huang C,Wang J,Li J,Zhu X,Yan X
Fri Jan 15 00:00:00 EST 2021
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
Journal of immunology research
Yang B,Chen J,Teng Y
Mon Nov 29 00:00:00 EST 2021
G3BP1 Inhibition Alleviates Intracellular Nucleic Acid-Induced Autoimmune Responses.
Journal of immunology (Baltimore, Md. : 1950)
Cai H,Liu X,Zhang F,Han QY,Liu ZS,Xue W,Guo ZL,Zhao JM,Sun LM,Wang N,Mao J,He K,Xia T,Chen Y,Chen L,Li AL,Zhou T,Zhang XM,Li WH,Li T
Sat May 15 00:00:00 EDT 2021
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease.
Journal of neuroinflammation
Chen J,Mao K,Yu H,Wen Y,She H,Zhang H,Liu L,Li M,Li W,Zou F
Mon Dec 20 00:00:00 EST 2021
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Fitoterapia
Jin J,Zhou M,Wang X,Liu M,Huang H,Yan F,Yu Z,Shu X,Huo X,Feng L,Zhang B,Huang S,Deng S,Wang C,Ma X
Fri Jan 01 00:00:00 EST 2021
MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling.
Cellular & molecular immunology
Li D,Chen S,Zhang W,Zhang C,Sun T,Du Y,Ding R,Gao Y,Jin Y,Duan G
Sat May 01 00:00:00 EDT 2021
Impact of a long-term high-glucose environment on pro-inflammatory responses in macrophages stimulated with lipopolysaccharide.
Naunyn-Schmiedeberg's archives of pharmacology
Suzuki T,Yamashita S,Hattori K,Matsuda N,Hattori Y
Fri Oct 01 00:00:00 EDT 2021
Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway.
Translational oncology
Liu K,Song J,Yan Y,Zou K,Che Y,Wang B,Li Z,Yu W,Guo W,Zou L,Deng W,Sun X
Fri Jan 01 00:00:00 EST 2021
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Nature communications
Hao K,Chen Y,Yan X,Zhu X
Tue Nov 30 00:00:00 EST 2021
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Viruses
Wang Q,Xin Q,Shang W,Wan W,Xiao G,Zhang LK
Tue May 25 00:00:00 EDT 2021
A CD10-OGP Membrane Peptolytic Signaling Axis in Fibroblasts Regulates Lipid Metabolism of Cancer Stem Cells via SCD1.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yu S,Lu Y,Su A,Chen J,Li J,Zhou B,Liu X,Xia Q,Li Y,Li J,Huang M,Ye Y,Zhao Q,Jiang S,Yan X,Wang X,Di C,Pan J,Su S
Fri Oct 01 00:00:00 EDT 2021
Daidzein alleviates cisplatin-induced muscle atrophy by regulating Glut4/AMPK/FoxO pathway.
Phytotherapy research : PTR
Zhang H,Chi M,Chen L,Sun X,Wan L,Yang Q,Guo C
Sun Aug 01 00:00:00 EDT 2021
Polybrominated diphenyl ethers quinone exhibits neurotoxicity by inducing DNA damage, cell cycle arrest, apoptosis and p53-driven adaptive response in microglia BV2 cells.
Toxicology
Liu Z,Zhu Q,Song E,Song Y
Tue Jun 15 00:00:00 EDT 2021
Capping protein regulator and myosin 1 linker 3 regulates transcription of key cytokines in activated phagocytic cells.
Cellular signalling
Zhao N,Dong W,Kim H,Moallemian R,Lv J,Wang H,Zheng H,Wei F,Ma X
Mon Feb 01 00:00:00 EST 2021
Hydrogen Promotes the M1 Macrophage Conversion During the Polarization of Macrophages in Necrotizing Enterocolitis.
Frontiers in pediatrics
Yu S,Lv Z,Gao Z,Shi J,Sheng Q,Zheng L,Zhou J,Wang X
Tue Dec 07 00:00:00 EST 2021
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2.
Toxicology and applied pharmacology
Sun M,Guo M,Ma G,Zhang N,Pan F,Fan X,Wang R
Wed Sep 01 00:00:00 EDT 2021
The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells.
Cell proliferation
Ke W,Wang B,Hua W,Song Y,Lu S,Luo R,Li G,Wang K,Liao Z,Xiang Q,Li S,Wu X,Zhang Y,Yang C
Mon Feb 01 00:00:00 EST 2021
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Acta neuropathologica
Zhong S,Lian Y,Luo W,Luo R,Wu X,Ji J,Ji Y,Ding J,Wang X
Wed Dec 01 00:00:00 EST 2021
Mitoquinone ameliorates cigarette smoke-induced airway inflammation and mucus hypersecretion in mice.
International immunopharmacology
Yang D,Xu D,Wang T,Yuan Z,Liu L,Shen Y,Wen F
Fri Jan 01 00:00:00 EST 2021
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Cell death & disease
Lu D,Song Y,Yu Y,Wang D,Liu B,Chen L,Li X,Li Y,Cheng L,Lv F,Zhang P,Xing Y
Thu Aug 12 00:00:00 EDT 2021
Nuclear translocation of the receptor tyrosine kinase c-MET reduces the treatment efficacies of olaparib and gemcitabine in pancreatic ductal adenocarcinoma cells.
American journal of cancer research
Gao Y,Chen MK,Chu YY,Yang L,Yu D,Liu Y,Hung MC
Wed Feb 03 00:00:00 EST 2021
NT157 Inhibits HCC Migration via Downregulating the STAT3/Jab1 Signaling Pathway.
Technology in cancer research & treatment
Yu S,Wang Y,Lv K,Hou J,Li W,Wang X,Guo H,Wang W
Wed Jan 05 00:00:00 EST 2022
3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice.
ImmunoHorizons
Hoshi M,Kubo H,Ando T,Tashita C,Nakamoto K,Yamamoto Y,Tezuka H,Saito K
Mon Jun 28 00:00:00 EDT 2021
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Experimental cell research
Xi X,Zhao Y,Liu H,Li Z,Chen S,Liu D
Tue Jun 15 00:00:00 EDT 2021
SLC7A2 deficiency promotes hepatocellular carcinoma progression by enhancing recruitment of myeloid-derived suppressors cells.
Cell death & disease
Xia S,Wu J,Zhou W,Zhang M,Zhao K,Liu J,Tian D,Liao J
Wed Jun 02 00:00:00 EDT 2021
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
International immunopharmacology
Chen C,Gu J,Wang J,Wu Y,Yang A,Chen T,Zhou T,Liu Z
Fri Jan 01 00:00:00 EST 2021
Serotonin transporter regulation by cholesterol-independent lipid signaling.
Biochemical pharmacology
Deveau CM,Rodriguez E,Schroering A,Yamamoto BK
Fri Jan 01 00:00:00 EST 2021
Exogenous H2 S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Journal of cellular and molecular medicine
Zhang L,Jiang X,Liu N,Li M,Kang J,Chen L,Tang J,Dong S,Lu F,Zhang W
Wed Sep 01 00:00:00 EDT 2021
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis.
Environmental toxicology
Meng X,Zhang L,Han B,Zhang Z
Mon Nov 01 00:00:00 EDT 2021
Asparaginyl endopeptidase (AEP) regulates myocardial apoptosis in response to radiation exposure via alterations in NRF2 activation.
American journal of cancer research
Cao L,Xu C,Yi P,Li H,Lin Y,Cai G,Wang S,Ou D,Li M,Chen J
Fri May 07 00:00:00 EDT 2021
Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.
Journal of ethnopharmacology
Qin W,Tong X,Liang R,Tang K,Wu X,Jia Y,Tan N
Mon May 10 00:00:00 EDT 2021
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.
International immunopharmacology
Zhu F,Shao J,Tian Y,Xu Z
Wed Dec 01 00:00:00 EST 2021
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus.
European journal of pharmacology
Wang J,Chen R,Liu C,Wu X,Zhang Y
Fri Oct 15 00:00:00 EDT 2021
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
International journal of biological sciences
Zhang T,Beeharry MK,Wang Z,Zhu Z,Li J,Li C
Wed Mar 30 00:00:00 EDT 2022
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Environmental toxicology
Wu B,Yang C,Fang Y,Ding W,Zhang Y
Sat May 01 00:00:00 EDT 2021
Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.
Frontiers in pharmacology
Chen P,Wen Z,Shi W,Li Z,Chen X,Gao Y,Xu S,Gong Q,Deng J
Tue Oct 26 00:00:00 EDT 2021
Mist1 Inhibits Epithelial-Mesenchymal Transition in Gastric Adenocarcinoma via Downregulating the Wnt/β-catenin Pathway.
Journal of Cancer
Xie X,Zhou Z,Song Y,Zhang X,Dang C,Zhang H
Tue Nov 07 00:00:00 EST 2023
18β-Glycyrrhetinic acid inhibits IL-1β-induced inflammatory response in mouse chondrocytes and prevents osteoarthritic progression by activating Nrf2.
Food & function
Chen B,Zhu D,Xie C,Shi Y,Ni L,Zhang H,Li S,Lu J,Xiao J,Xia W,Huang C,Wang X
Mon Sep 20 00:00:00 EDT 2021
Protein kinase D participates in cardiomyocyte hypertrophy by regulating extracellular signal-regulated and myocyte enhancer factor 2D.
Revista portuguesa de cardiologia
Yuan H,Xiang Q,Yang L,Geng J
Mon Mar 01 00:00:00 EST 2021
Immunomodulation effects of polyphenols from thinned peach treated by different drying methods on RAW264.7 cells through the NF-κB and Nrf2 pathways.
Food chemistry
Guo C,Bi J,Li X,Lyu J,Liu X,Wu X,Liu J
Mon Mar 15 00:00:00 EDT 2021
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection.
Immunity
Xiao J,Li W,Zheng X,Qi L,Wang H,Zhang C,Wan X,Zheng Y,Zhong R,Zhou X,Lu Y,Li Z,Qiu Y,Liu C,Zhang F,Zhang Y,Xu X,Yang Z,Chen H,Zhai Q,Wei B,Wang H
Tue Jan 14 00:00:00 EST 2020
Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity.
Neuron
Ortega JA,Daley EL,Kour S,Samani M,Tellez L,Smith HS,Hall EA,Esengul YT,Tsai YH,Gendron TF,Donnelly CJ,Siddique T,Savas JN,Pandey UB,Kiskinis E
Wed Apr 08 00:00:00 EDT 2020
Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity.
Neuron
Ortega JA,Daley EL,Kour S,Samani M,Tellez L,Smith HS,Hall EA,Esengul YT,Tsai YH,Gendron TF,Donnelly CJ,Siddique T,Savas JN,Pandey UB,Kiskinis E
Wed Apr 08 00:00:00 EDT 2020
USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2.
The Journal of experimental medicine
Cai Z,Zhang MX,Tang Z,Zhang Q,Ye J,Xiong TC,Zhang ZD,Zhong B
Mon May 04 00:00:00 EDT 2020
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.
British journal of pharmacology
Sikura KÉ,Potor L,Szerafin T,Oros M,Nagy P,Méhes G,Hendrik Z,Zarjou A,Agarwal A,Posta N,Torregrossa R,Whiteman M,Fürtös I,Balla G,Balla J
Sat Feb 01 00:00:00 EST 2020
USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.
PLoS pathogens
Liu J,Jin L,Chen X,Yuan Y,Zuo Y,Miao Y,Feng Q,Zhang H,Huang F,Guo T,Zhang L,Zhu L,Qian F,Zhu C,Zheng H
Wed Jan 01 00:00:00 EST 2020
The G Protein-Coupled Receptor FFAR2 Promotes Internalization during Influenza A Virus Entry.
Journal of virology
Wang G,Jiang L,Wang J,Zhang J,Kong F,Li Q,Yan Y,Huang S,Zhao Y,Liang L,Li J,Sun N,Hu Y,Shi W,Deng G,Chen P,Liu L,Zeng X,Tian G,Bu Z,Chen H,Li C
Mon Jan 06 00:00:00 EST 2020
Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction.
Laboratory investigation; a journal of technical methods and pathology
Posta N,Csősz É,Oros M,Pethő D,Potor L,Kalló G,Hendrik Z,Sikura KÉ,Méhes G,Tóth C,Posta J,Balla G,Balla J
Wed Jul 01 00:00:00 EDT 2020
LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient.
PLoS biology
Lee J,Park J,Kim JH,Lee G,Park TE,Yoon KJ,Kim YK,Lim C
Tue Dec 01 00:00:00 EST 2020
Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats.
Brain research
Li Y,Wu J,Yu S,Zhu J,Zhou Y,Wang P,Li L,Zhao Y
Thu Oct 15 00:00:00 EDT 2020
Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.
International journal of molecular sciences
Fujiwara-Tani R,Fujii K,Mori S,Kishi S,Sasaki T,Ohmori H,Nakashima C,Kawahara I,Nishiguchi Y,Mori T,Sho M,Kondoh M,Luo Y,Kuniyasu H
Thu May 28 00:00:00 EDT 2020
Naturally-derived diterpenoid sphaeropsidin C as an activator of Nrf2/ARE pathway and its potential capability of relieving intracellular oxidative stress in human lung epithelial cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li GH,Li AL,Chen XM,Zhang LY,Wang T,Wang XN,Shen T
Wed Jan 01 00:00:00 EST 2020
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
Molecular medicine reports
He H,Xu C,Zheng L,Wang K,Jin M,Sun Y,Yue Z
Sat Feb 01 00:00:00 EST 2020
Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques.
Oxidative medicine and cellular longevity
Zavaczki E,Gáll T,Zarjou A,Hendrik Z,Potor L,Tóth CZ,Méhes G,Gyetvai Á,Agarwal A,Balla G,Balla J
Tue Nov 10 00:00:00 EST 2020
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Oncology reports
Luo W,Zhang H,Liang X,Xia R,Deng H,Yi Q,Lv L,Qian L
Fri May 01 00:00:00 EDT 2020
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
International immunopharmacology
Wu Y,Wang Z,Fu X,Lin Z,Yu K
Tue Sep 01 00:00:00 EDT 2020
Circular RNA GLIS2 promotes colorectal cancer cell motility via activation of the NF-κB pathway.
Cell death & disease
Chen J,Yang X,Liu R,Wen C,Wang H,Huang L,Li W,Zhu Z,Zhu Y,Liu H
Wed Sep 23 00:00:00 EDT 2020
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia.
The Journal of experimental medicine
Zhang B,Ma H,Khan T,Ma A,Li T,Zhang H,Gao J,Zhou J,Li Y,Yu C,Bao J,Ali A,Murtaza G,Yin H,Gao Q,Jiang X,Zhang F,Liu C,Khan I,Zubair M,Hussain HMJ,Khan R,Yousaf A,Yuan L,Lu Y,Xu X,Wang Y,Tao Q,Hao Q,Fang H,Cheng H,Zhang Y,Shi Q
Mon Feb 03 00:00:00 EST 2020
Repositioning an Immunomodulatory Drug Vidofludimus as a Farnesoid X Receptor Modulator With Therapeutic Effects on NAFLD.
Frontiers in pharmacology
Zhu Y,Xu S,Lu Y,Wei Y,Yao B,Guo F,Zheng X,Wang Y,He Y,Jin L,Li Y
Mon Sep 28 00:00:00 EDT 2020
LncRNA AC010789.1 Promotes Colorectal Cancer Progression by Targeting MicroRNA-432-3p/ZEB1 Axis and the Wnt/β-Catenin Signaling Pathway.
Frontiers in cell and developmental biology
Duan W,Kong X,Li J,Li P,Zhao Y,Liu T,Binang HB,Wang Y,Du L,Wang C
Fri Nov 13 00:00:00 EST 2020
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
EBioMedicine
Luo X,Li Y,Yang P,Chen Y,Wei L,Yu T,Xia J,Ruan XZ,Zhao L,Chen Y
Mon Jun 01 00:00:00 EDT 2020
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Oxidative medicine and cellular longevity
Zhou X,Liu Z,Ying K,Wang H,Liu P,Ji X,Chi T,Zou L,Wang S,He Z
Wed Jan 27 00:00:00 EST 2021
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma.
Journal of Cancer
Zhu G,Li X,Li J,Zhou W,Chen Z,Fan Y,Jiang Y,Zhao Y,Sun G,Mao W
Fri Oct 16 00:00:00 EDT 2020
Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses.
Life sciences
Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X
Sat Feb 15 00:00:00 EST 2020
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Cancer science
Yu YP,Cai LC,Wang XY,Cheng SY,Zhang DM,Jian WG,Wang TD,Yang JK,Yang KB,Zhang C
Fri May 01 00:00:00 EDT 2020
SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma.
Theranostics
Xu H,Wang H,Zhao W,Fu S,Li Y,Ni W,Xin Y,Li W,Yang C,Bai Y,Zhan M,Lu L
Mon Aug 02 00:00:00 EDT 2021
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
Nature communications
Zuo Y,Feng Q,Jin L,Huang F,Miao Y,Liu J,Xu Y,Chen X,Zhang H,Guo T,Yuan Y,Zhang L,Wang J,Zheng H
Mon Mar 02 00:00:00 EST 2020
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo.
Frontiers in pharmacology
Wu Y,Wang Z,Lin Z,Fu X,Zhan J,Yu K
Mon Sep 28 00:00:00 EDT 2020
S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway.
Aging
Shao Z,Pan Z,Lin J,Zhao Q,Wang Y,Ni L,Feng S,Tian N,Wu Y,Sun L,Gao W,Zhou Y,Zhang X,Wang X
Wed Oct 07 00:00:00 EDT 2020
Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop.
Cell proliferation
Sun Q,Fan G,Zhuo Q,Dai W,Ye Z,Ji S,Xu W,Liu W,Hu Q,Zhang Z,Liu M,Yu X,Xu X,Qin Y
Fri May 01 00:00:00 EDT 2020
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Cell communication and signaling : CCS
Xu A,Yang Y,Shao Y,Wu M,Sun Y
Wed Jan 15 00:00:00 EST 2020
Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1.
Cell death & disease
Chen Y,Wu Y,Yu S,Yang H,Wang X,Zhang Y,Zhu S,Jie M,Liu C,Li X,Zhou Y,Yang S,Yang Y
Thu Jul 23 00:00:00 EDT 2020
1,25-Dihydroxyvitamin D attenuates diabetic cardiac autophagy and damage by vitamin D receptor-mediated suppression of FoxO1 translocation.
The Journal of nutritional biochemistry
Guo X,Lin H,Liu J,Wang D,Li D,Jiang C,Tang Y,Wang J,Zhang T,Li Y,Yao P
Mon Jun 01 00:00:00 EDT 2020
Peroxisome proliferator activated receptor γ promotes mineralization and differentiation in cementoblasts via inhibiting Wnt/β-catenin signaling pathway.
Journal of cellular biochemistry
Hu Y,Wang C,Ha S,Zhu N,Cao Z,Song Y
Sat Aug 01 00:00:00 EDT 2020
Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins.
Frontiers in microbiology
Zhang X,Lin X,Qin C,Huang K,Sun X,Zhao L,Jin M
Fri Nov 13 00:00:00 EST 2020
Nintedanib Inhibits Wnt3a-Induced Myofibroblast Activation by Suppressing the Src/β-Catenin Pathway.
Frontiers in pharmacology
Li X,Liu X,Deng R,Gao S,Yu H,Huang K,Jiang Q,Liu R,Li X,Zhang L,Zhou H,Yang C
Mon Sep 28 00:00:00 EDT 2020
Expressional Localization and Functionally Identifying an RNA Editing Enzyme BmADARa of the Silkworm Bombyx mori.
Insects
Ye C,Jiang S,Gong M,Min Q,Fan M,Gao J,Meng Y
Wed Aug 12 00:00:00 EDT 2020
Aryl hydrocarbon receptor signaling activation in systemic sclerosis attenuates collagen production and is a potential antifibrotic target.
International immunopharmacology
Shi Y,Tang B,Yu J,Luo Y,Xiao Y,Pi Z,Tang R,Wang Y,Kanekura T,Zeng Z,Xiao R
Sun Nov 01 00:00:00 EDT 2020
Histone Variant H2A.J Marks Persistent DNA Damage and Triggers the Secretory Phenotype in Radiation-Induced Senescence.
International journal of molecular sciences
Isermann A,Mann C,Rübe CE
Mon Nov 30 00:00:00 EST 2020
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Life sciences
Zhao X,Shi Y,Zhang D,Tong X,Sun Y,Xue X,Fu J
Wed Jul 01 00:00:00 EDT 2020
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Brain sciences
Sivalingam K,Samikkannu T
Sat Sep 05 00:00:00 EDT 2020
Vitamin D3 protects articular cartilage by inhibiting the Wnt/β-catenin signaling pathway.
Experimental and therapeutic medicine
Yang T,Sun W,Duan YH,Sun YB,Ren YM,Hou WY,Tian MQ
Sat Aug 01 00:00:00 EDT 2020
Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin.
ACS chemical neuroscience
Le K,Wu S,Chibaatar E,Ali AI,Guo Y
Wed Mar 18 00:00:00 EDT 2020
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Pharmaceutical biology
Zhang X,Feng J,Su S,Huang L
Tue Dec 01 00:00:00 EST 2020
Rspo1/Rspo3-LGR4 signaling inhibits hepatic cholesterol synthesis through the AMPKα-SREBP2 pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu S,Gao Y,Zhang L,Yin Y,Zhang W
Sun Nov 01 00:00:00 EDT 2020
Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.
International journal of molecular sciences
Wang Y,Kong W,Wang L,Zhang T,Huang B,Meng J,Yang B,Xie Z,Zhou H
Sun Oct 18 00:00:00 EDT 2020
Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats.
Oxidative medicine and cellular longevity
Yu J,Wang WN,Matei N,Li X,Pang JW,Mo J,Chen SP,Tang JP,Yan M,Zhang JH
Wed Jun 03 00:00:00 EDT 2020
SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.
Journal of cellular and molecular medicine
Sun K,Wang X,Fang N,Xu A,Lin Y,Zhao X,Nazarali AJ,Ji S
Wed Jul 01 00:00:00 EDT 2020
Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.
Aging cell
Mao K,Chen J,Yu H,Li H,Ren Y,Wu X,Wen Y,Zou F,Li W
Mon Jun 01 00:00:00 EDT 2020
Low-Dose Berberine Attenuates the Anti-Breast Cancer Activity of Chemotherapeutic Agents via Induction of Autophagy and Antioxidation.
Dose-response : a publication of International Hormesis Society
Han B,Wang K,Tu Y,Tan L,He C
Wed Oct 28 00:00:00 EDT 2020
Down-regulation of exosomal miR-200c derived from keratinocytes in vitiligo lesions suppresses melanogenesis.
Journal of cellular and molecular medicine
Zhao C,Wang D,Wang X,Mao Y,Xu Z,Sun Y,Mei X,Song J,Shi W
Thu Oct 01 00:00:00 EDT 2020
Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells.
Oncology letters
Li Y,Xie J,Li X,Fang J
Wed Jan 01 00:00:00 EST 2020
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Metabolism: clinical and experimental
Tian L,Xiao H,Li M,Wu X,Xie Y,Zhou J,Zhang X,Wang B
Wed Apr 01 00:00:00 EDT 2020
The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance.
Cell proliferation
Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X
Sun Mar 01 00:00:00 EST 2020
Facile Cholesterol Loading with a New Probe ezFlux Allows for Streamlined Cholesterol Efflux Assays.
ACS omega
Ravodina AM,Badgeley MA,Rajagopalan S,Fedyukina DV,Maiseyeu A
Tue Sep 15 00:00:00 EDT 2020
The zinc-finger protein ZFYVE1 modulates TLR3-mediated signaling by facilitating TLR3 ligand binding.
Cellular & molecular immunology
Zhong X,Feng L,Xu WH,Wu X,Ding YD,Zhou Y,Lei CQ,Shu HB
Wed Jul 01 00:00:00 EDT 2020
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhang B,Yu D,Luo N,Yang C,Zhu Y
Tue Sep 01 00:00:00 EDT 2020
Lycopene Exerts Neuroprotective Effects After Hypoxic-Ischemic Brain Injury in Neonatal Rats via the Nuclear Factor Erythroid-2 Related Factor 2/Nuclear Factor-κ-Gene Binding Pathway.
Frontiers in pharmacology
Fu C,Zheng Y,Zhu J,Chen B,Lin W,Lin K,Zhu J,Chen S,Li P,Fu X,Lin Z
Tue Jan 05 00:00:00 EST 2021
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Journal of cellular and molecular medicine
Dong P,Fu H,Chen L,Zhang S,Zhang X,Li H,Wu D,Ji X
Wed Jul 01 00:00:00 EDT 2020
AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB Pathway.
Journal of atherosclerosis and thrombosis
Ren J,Han Y,Ren T,Fang H,Xu X,Lun Y,Jiang H,Xin S,Zhang J
Sun Mar 01 00:00:00 EST 2020
[PARP10 Influences the Proliferation of Colorectal Carcinoma Cells, a Preliminary Study].
Molekuliarnaia biologiia
Wu CF,Xiao M,Wang YL,Threadgill MD,Li M,Tang Y,Lin X,Yang L,Li QS,Li X
Wed Aug 19 00:00:00 EDT 2020
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Aging
Jiang W,Yan Y,Chen M,Luo G,Hao J,Pan J,Hu S,Guo P,Li W,Wang R,Zuo Y,Sun Y,Sui S,Yu W,Pan Z,Zou K,Zheng Z,Deng W,Wu X,Guo W
Mon Jan 06 00:00:00 EST 2020
Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo.
Drug design, development and therapy
Wang H,Jiang Z,Pang Z,Zhou T,Gu Y
Mon Aug 23 00:00:00 EDT 2021
Novel role of ASH1L histone methyltransferase in anaplastic thyroid carcinoma.
The Journal of biological chemistry
Xu B,Qin T,Yu J,Giordano TJ,Sartor MA,Koenig RJ
Fri Jun 26 00:00:00 EDT 2020
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
Nature metabolism
Li ST,Huang D,Shen S,Cai Y,Xing S,Wu G,Jiang Z,Hao Y,Yuan M,Wang N,Zhu L,Yan R,Yang D,Wang L,Liu Z,Hu X,Zhou R,Qu K,Li A,Duan X,Zhang H,Gao P
Sun Mar 01 00:00:00 EST 2020
Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.
Journal of medicinal chemistry
Mackie BD,Chen D,Dong G,Dong C,Parker H,Schaner Tooley CE,Noinaj N,Min J,Huang R
Thu Sep 10 00:00:00 EDT 2020
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
International immunopharmacology
Huang H,Cai H,Zhang L,Hua Z,Shi J,Wei Y
Sun Mar 01 00:00:00 EST 2020
Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production.
Toxicology letters
Zhang W,Xiong H,Pang J,Su Z,Lai L,Lin H,Jian B,He W,Yang H,Zheng Y
Thu Oct 01 00:00:00 EDT 2020
Reduced hydration-induced decreased caveolin-1 expression causes epithelial-to-mesenchymal transition.
American journal of translational research
Yang S,Zhao J,Huang S,Shu B,Yang R,Chen L,Xu Y,Xie J,Liu X,Jia J,Qi S
Thu Jan 14 00:00:00 EST 2021
Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice.
BioMed research international
Du J,He W,Zhang C,Wu J,Li Z,Wang M,Feng S,Liang G
Mon Nov 23 00:00:00 EST 2020
SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia.
Cancer biology & therapy
Kong Q,Li Y,Liang Q,Xie J,Li X,Fang J
Thu Apr 02 00:00:00 EDT 2020
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
Cell death & disease
Cui Y,Li F,Xie Q,Zhao S,Guo T,Guo P,Hu S,Hao J,Tian C,Yu W,Li Z,Fang L,Zhao L,Chen M,Wu T,Gu C
Fri Jun 19 00:00:00 EDT 2020
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Cancer science
Ding XY,Hu HY,Huang KN,Wei RQ,Min J,Qi C,Tang H,Qin X
Sat Feb 01 00:00:00 EST 2020
GADD45G Interacts with E-cadherin to Suppress the Migration and Invasion of Esophageal Squamous Cell Carcinoma.
Digestive diseases and sciences
Li T,Xu L,Teng J,Ma Y,Liu W,Wang Y,Chi X,Shao S,Dong Y,Zhan Q,Liu X
Wed Apr 01 00:00:00 EDT 2020
RGS12 Is a Novel Critical NF-κB Activator in Inflammatory Arthritis.
iScience
Yuan G,Yang S,Ng A,Fu C,Oursler MJ,Xing L,Yang S
Fri Jun 26 00:00:00 EDT 2020
Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation.
Cell death & disease
Zohud BA,Guo P,Zohud BA,Li F,Hao JJ,Shan X,Yu W,Guo W,Qin Y,Cai X
Tue Oct 20 00:00:00 EDT 2020
Decreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression.
Journal of neurochemistry
Shanley KL,Hu CL,Bizzozero OA
Sun Mar 01 00:00:00 EST 2020
EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer.
Cell death & disease
Li Y,Liu J,Xiao Q,Tian R,Zhou Z,Gan Y,Li Y,Shu G,Yin G
Thu Jul 30 00:00:00 EDT 2020
Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation.
Oxidative medicine and cellular longevity
Jin M,Feng H,Wang Y,Yan S,Shen B,Li Z,Qin H,Wang Q,Li J,Liu G
Wed May 05 00:00:00 EDT 2021
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Journal of gastroenterology and hepatology
Pan B,Liu L,Hu X,Sun X,Zhu Y,Zhang T,Wei D,Guo Y,Shan J
Tue Dec 01 00:00:00 EST 2020
Inhibition of Siah2 ubiquitin ligase ameliorates monocrotaline-induced pulmonary arterial remodeling through inactivation of YAP.
Life sciences
Wang Q,Shi W,Zhang Q,Feng W,Wang J,Zhai C,Yan X,Li M
Sat Feb 01 00:00:00 EST 2020
SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Autophagy
Lee DH,Park JS,Lee YS,Han J,Lee DK,Kwon SW,Han DH,Lee YH,Bae SH
Sun Nov 01 00:00:00 EDT 2020
Ribosome profiling analysis identified a KRAS-interacting microprotein that represses oncogenic signaling in hepatocellular carcinoma cells.
Science China. Life sciences
Xu W,Deng B,Lin P,Liu C,Li B,Huang Q,Zhou H,Yang J,Qu L
Wed Apr 01 00:00:00 EDT 2020
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Frontiers in cell and developmental biology
Shao Z,Tu Z,Shi Y,Li S,Wu A,Wu Y,Tian N,Sun L,Pan Z,Chen L,Gao W,Zhou Y,Wang X,Zhang X
Fri Dec 18 00:00:00 EST 2020
UBE2M promotes cell proliferation via the β-catenin/cyclin D1 signaling in hepatocellular carcinoma.
Aging
Zhang GC,Yu XN,Sun JL,Xiong J,Yang YJ,Jiang XM,Zhu JM
Mon Feb 03 00:00:00 EST 2020
RNA demethylase Alkbh5 is widely expressed in neurons and decreased during brain development.
Brain research bulletin
Du T,Li G,Yang J,Ma K
Thu Oct 01 00:00:00 EDT 2020
Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs.
Cell reports
Cabukusta B,Berlin I,van Elsland DM,Forkink I,Spits M,de Jong AWM,Akkermans JJLL,Wijdeven RHM,Janssen GMC,van Veelen PA,Neefjes J
Tue Dec 08 00:00:00 EST 2020
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
Molecular neurobiology
Sun Y,He L,Wang T,Hua W,Qin H,Wang J,Wang L,Gu W,Li T,Li N,Liu X,Chen F,Tang L
Sun Nov 01 00:00:00 EDT 2020
Nuclear-localized costimulatory molecule 4-1BBL promotes colon cancer cell proliferation and migration by regulating nuclear Gsk3β, and is linked to the poor outcomes associated with colon cancer.
Cell cycle (Georgetown, Tex.)
Ge Y,Chen W,Zhang X,Wang H,Cui J,Liu Y,Ju S,Tian X,Ju S
Sun Mar 01 00:00:00 EST 2020
Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.
Cell reports
Burrus CJ,McKinstry SU,Kim N,Ozlu MI,Santoki AV,Fang FY,Ma A,Karadeniz YB,Worthington AK,Dragatsis I,Zeitlin S,Yin HH,Eroglu C
Tue Jan 21 00:00:00 EST 2020
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Herz
Yu T,Dong D,Guan J,Sun J,Guo M,Wang Q
Tue Dec 01 00:00:00 EST 2020
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.
Cancer discovery
Zhou Y,Han C,Wang E,Lorch AH,Serafin V,Cho BK,Gutierrez Diaz BT,Calvo J,Fang C,Khodadadi-Jamayran A,Tabaglio T,Marier C,Kuchmiy A,Sun L,Yacu G,Filip SK,Jin Q,Takahashi YH,Amici DR,Rendleman EJ,Rawat R,Bresolin S,Paganin M,Zhang C,Li H,Kandela I,Politanska Y,Abdala-Valencia H,Mendillo ML,Zhu P,Palhais B,Van Vlierberghe P,Taghon T,Aifantis I,Goo YA,Guccione E,Heguy A,Tsirigos A,Wee KB,Mishra RK,Pflumio F,Accordi B,Basso G,Ntziachristos P
Tue Sep 01 00:00:00 EDT 2020
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
Oncogene
Qi M,Dai D,Liu J,Li Z,Liang P,Wang Y,Cheng L,Zhan Y,An Z,Song Y,Yang Y,Yan X,Xiao H,Shao H
Sun Mar 01 00:00:00 EST 2020
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
Evidence-based complementary and alternative medicine : eCAM
Tian TT,Li QR,Gan SQ,Chang CR,Shen XC
Mon Sep 28 00:00:00 EDT 2020
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Aquaculture (Amsterdam, Netherlands)
Zhang Y,Zhang X,Liang Z,Dai K,Zhu M,Zhang M,Pan J,Xue R,Cao G,Tang J,Song X,Hu X,Gong C
Wed Apr 15 00:00:00 EDT 2020
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Aging
Ding S,Ma N,Liu H,Tang M,Mei J
Tue Nov 24 00:00:00 EST 2020
Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling.
Redox biology
Yen WC,Wu YH,Wu CC,Lin HR,Stern A,Chen SH,Shu JC,Tsun-Yee Chiu D
Wed Jan 01 00:00:00 EST 2020
FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy.
Biochemical and biophysical research communications
Wang Y,Yang Y,Zuo R,Wu J,Zhang C,Li C,Liu M,Zhou Y
Thu Apr 09 00:00:00 EDT 2020
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization.
Molecular and cellular probes
Zhao L,Li R,Qiu JZ,Yu JB,Cao Y,Yuan RT
Thu Oct 01 00:00:00 EDT 2020
Lamin B1 deficiency promotes malignancy and predicts poor prognosis in gastric cancer.
Neoplasma
Yu ZY,Jiang XY,Zhao RR,Luo CJ,Ren YX,Ma ZJ,Ye HL,Shi WG,Wang C,Jiao ZY
Sun Nov 01 00:00:00 EDT 2020
Inhibition of ROCK2 alleviates renal fibrosis and the metabolic disorders in the proximal tubular epithelial cells.
Clinical science (London, England : 1979)
You R,Zhou W,Li Y,Zhang Y,Huang S,Jia Z,Zhang A
Fri Jun 26 00:00:00 EDT 2020
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
Cells
He X,Chen S,Li C,Ban J,Wei Y,He Y,Liu F,Chen Y,Chen J
Sat Jan 04 00:00:00 EST 2020
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Journal of experimental & clinical cancer research : CR
Sun J,Zhu Z,Li W,Shen M,Cao C,Sun Q,Guo Z,Liu L,Wu D
Wed Oct 21 00:00:00 EDT 2020
Singapore Grouper Iridovirus (SGIV) Inhibited Autophagy for Efficient Viral Replication.
Frontiers in microbiology
Li C,Wang L,Liu J,Yu Y,Huang Y,Huang X,Wei J,Qin Q
Mon Sep 28 00:00:00 EDT 2020
Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas.
Oncotarget
Nakashima C,Yamamoto K,Kishi S,Sasaki T,Ohmori H,Fujiwara-Tani R,Mori S,Kawahara I,Nishiguchi Y,Mori T,Kondoh M,Luo Y,Kirita T,Kuniyasu H
Tue Jan 28 00:00:00 EST 2020
Regulation of a PRMT5/NF-κB Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer.
International journal of molecular sciences
Hartley AV,Wang B,Jiang G,Wei H,Sun M,Prabhu L,Martin M,Safa A,Sun S,Liu Y,Lu T
Sat May 23 00:00:00 EDT 2020
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
International immunopharmacology
Lang L,Xu B,Yuan J,Li S,Lian S,Chen Y,Guo J,Yang H
Tue Dec 01 00:00:00 EST 2020
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway.
Journal of cellular and molecular medicine
Zhang S,Wang H,Liu Y,Yang W,Liu J,Han Y,Liu Y,Liu F,Sun L,Xiao L
Tue Sep 01 00:00:00 EDT 2020
Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity.
Autophagy
Park JS,Lee DH,Lee YS,Oh E,Bae KH,Oh KJ,Kim H,Bae SH
Wed Jan 01 00:00:00 EST 2020
Linalool Prevents Cisplatin Induced Muscle Atrophy by Regulating IGF-1/Akt/FoxO Pathway.
Frontiers in pharmacology
Zhang H,Chi M,Chen L,Sun X,Wan L,Yang Q,Guo C
Tue Jan 05 00:00:00 EST 2021
ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3.
Oncogene
Li YL,Wu LW,Zeng LH,Zhang ZY,Wang W,Zhang C,Lin NM
Tue Sep 01 00:00:00 EDT 2020
Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress.
Oxidative medicine and cellular longevity
Bu W,Hao X,Yang T,Wang J,Liu Q,Zhang X,Li X,Gong Y,Shao C
Wed May 12 00:00:00 EDT 2021
The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest.
Cell
Trendel J,Schwarzl T,Horos R,Prakash A,Bateman A,Hentze MW,Krijgsveld J
Thu Jan 10 00:00:00 EST 2019
The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest.
Cell
Trendel J,Schwarzl T,Horos R,Prakash A,Bateman A,Hentze MW,Krijgsveld J
Thu Jan 10 00:00:00 EST 2019
Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells.
Small (Weinheim an der Bergstrasse, Germany)
Qi S,Zhang P,Ma M,Yao M,Wu J,Mäkilä E,Salonen J,Ruskoaho H,Xu Y,Santos HA,Zhang H
Tue Jan 01 00:00:00 EST 2019
Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells.
Small (Weinheim an der Bergstrasse, Germany)
Qi S,Zhang P,Ma M,Yao M,Wu J,Mäkilä E,Salonen J,Ruskoaho H,Xu Y,Santos HA,Zhang H
Tue Jan 01 00:00:00 EST 2019
USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research
Jin Q,Martinez CA,Arcipowski KM,Zhu Y,Gutierrez-Diaz BT,Wang KK,Johnson MR,Volk AG,Wang F,Wu J,Grove C,Wang H,Sokirniy I,Thomas PM,Goo YA,Abshiru NA,Hijiya N,Peirs S,Vandamme N,Berx G,Goosens S,Marshall SA,Rendleman EJ,Takahashi YH,Wang L,Rawat R,Bartom ET,Collings CK,Van Vlierberghe P,Strikoudis A,Kelly S,Ueberheide B,Mantis C,Kandela I,Bourquin JP,Bornhauser B,Serafin V,Bresolin S,Paganin M,Accordi B,Basso G,Kelleher NL,Weinstock J,Kumar S,Crispino JD,Shilatifard A,Ntziachristos P
Tue Jan 01 00:00:00 EST 2019
USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research
Jin Q,Martinez CA,Arcipowski KM,Zhu Y,Gutierrez-Diaz BT,Wang KK,Johnson MR,Volk AG,Wang F,Wu J,Grove C,Wang H,Sokirniy I,Thomas PM,Goo YA,Abshiru NA,Hijiya N,Peirs S,Vandamme N,Berx G,Goosens S,Marshall SA,Rendleman EJ,Takahashi YH,Wang L,Rawat R,Bartom ET,Collings CK,Van Vlierberghe P,Strikoudis A,Kelly S,Ueberheide B,Mantis C,Kandela I,Bourquin JP,Bornhauser B,Serafin V,Bresolin S,Paganin M,Accordi B,Basso G,Kelleher NL,Weinstock J,Kumar S,Crispino JD,Shilatifard A,Ntziachristos P
Tue Jan 01 00:00:00 EST 2019
Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia.
Autophagy
Liu Y,Xue X,Zhang H,Che X,Luo J,Wang P,Xu J,Xing Z,Yuan L,Liu Y,Fu X,Su D,Sun S,Zhang H,Wu C,Yang J
Fri Mar 01 00:00:00 EST 2019
Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia.
Autophagy
Liu Y,Xue X,Zhang H,Che X,Luo J,Wang P,Xu J,Xing Z,Yuan L,Liu Y,Fu X,Su D,Sun S,Zhang H,Wu C,Yang J
Fri Mar 01 00:00:00 EST 2019
Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion.
Cell death and differentiation
Li Y,Feng D,Wang Z,Zhao Y,Sun R,Tian D,Liu D,Zhang F,Ning S,Yao J,Tian X
Fri Nov 01 00:00:00 EDT 2019
Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.
Journal of molecular cell biology
Zhang Y,Chen Y,Zheng J,Wang J,Duan S,Zhang W,Yan X,Zhu X
Wed May 01 00:00:00 EDT 2019
Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.
Journal of molecular cell biology
Zhang Y,Chen Y,Zheng J,Wang J,Duan S,Zhang W,Yan X,Zhu X
Wed May 01 00:00:00 EDT 2019
PARP1 interacts with HMGB1 and promotes its nuclear export in pathological myocardial hypertrophy.
Acta pharmacologica Sinica
Li Q,Li ZM,Sun SY,Wang LP,Wang PX,Guo Z,Yang HW,Ye JT,Lu J,Liu PQ
Wed May 01 00:00:00 EDT 2019
PARP1 interacts with HMGB1 and promotes its nuclear export in pathological myocardial hypertrophy.
Acta pharmacologica Sinica
Li Q,Li ZM,Sun SY,Wang LP,Wang PX,Guo Z,Yang HW,Ye JT,Lu J,Liu PQ
Wed May 01 00:00:00 EDT 2019
Genistein inhibits Ang II-induced CRP and MMP-9 generations via the ER-p38/ERK1/2-PPARγ-NF-κB signaling pathway in rat vascular smooth muscle cells.
Life sciences
Xu L,Liu JT,Li K,Wang SY,Xu S
Tue Jan 01 00:00:00 EST 2019
Genistein inhibits Ang II-induced CRP and MMP-9 generations via the ER-p38/ERK1/2-PPARγ-NF-κB signaling pathway in rat vascular smooth muscle cells.
Life sciences
Xu L,Liu JT,Li K,Wang SY,Xu S
Tue Jan 01 00:00:00 EST 2019
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Molecular nutrition & food research
Lei P,Tian S,Teng C,Huang L,Liu X,Wang J,Zhang Y,Li B,Shan Y
Fri Feb 01 00:00:00 EST 2019
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
Molecular nutrition & food research
Lei P,Tian S,Teng C,Huang L,Liu X,Wang J,Zhang Y,Li B,Shan Y
Fri Feb 01 00:00:00 EST 2019
Attenuation of Atherosclerosis by Protocatechuic Acid via Inhibition of M1 and Promotion of M2 Macrophage Polarization.
Journal of agricultural and food chemistry
Liu Y,Wang X,Pang J,Zhang H,Luo J,Qian X,Chen Q,Ling W
Wed Jan 23 00:00:00 EST 2019
Attenuation of Atherosclerosis by Protocatechuic Acid via Inhibition of M1 and Promotion of M2 Macrophage Polarization.
Journal of agricultural and food chemistry
Liu Y,Wang X,Pang J,Zhang H,Luo J,Qian X,Chen Q,Ling W
Wed Jan 23 00:00:00 EST 2019
DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import.
Journal of cell science
Li D,Fu S,Wu Z,Yang W,Ru Y,Shu H,Liu X,Zheng H
Wed Jul 24 00:00:00 EDT 2019
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
Human mutation
Han M,Zhao M,Cheng C,Huang Y,Han S,Li W,Tu X,Luo X,Yu X,Liu Y,Chen Q,Ren X,Wang QK,Ke T
Fri Mar 01 00:00:00 EST 2019
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
Human mutation
Han M,Zhao M,Cheng C,Huang Y,Han S,Li W,Tu X,Luo X,Yu X,Liu Y,Chen Q,Ren X,Wang QK,Ke T
Fri Mar 01 00:00:00 EST 2019
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Journal of cellular biochemistry
Li Y,Chen Y,Qiu C,Ma X,Lei K,Cai G,Liang X,Liu J
Fri Feb 01 00:00:00 EST 2019
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Journal of cellular biochemistry
Li Y,Chen Y,Qiu C,Ma X,Lei K,Cai G,Liang X,Liu J
Fri Feb 01 00:00:00 EST 2019
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
Journal of gastroenterology and hepatology
Di X,He G,Chen H,Zhu C,Qin Q,Yan J,Zhang X,Sun X
Mon Apr 01 00:00:00 EDT 2019
High-mobility group box 1 protein modulated proliferation and radioresistance in esophageal squamous cell carcinoma.
Journal of gastroenterology and hepatology
Di X,He G,Chen H,Zhu C,Qin Q,Yan J,Zhang X,Sun X
Mon Apr 01 00:00:00 EDT 2019
Discovery of human TyrRS inhibitors by structure-based virtual screening, structural optimization, and bioassays.
RSC advances
Huang S,Wang X,Lin G,Cheng J,Chen X,Sun W,Xiang R,Yu Y,Li L,Yang S
Fri Mar 15 00:00:00 EDT 2019
Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling.
BMC veterinary research
Diao H,Cheng N,Zhao Y,Xu H,Dong H,Thamm DH,Zhang D,Lin D
Fri Aug 02 00:00:00 EDT 2019
Anacardic acid inhibits RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced bone loss in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhao K,Jia Y,Peng J,Pang C,Zhang T,Han W,Jiang J,Lu X,Zhu J,Qian Y
Thu Aug 01 00:00:00 EDT 2019
Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages.
Free radical biology & medicine
Hu Y,Gui Z,Zhou Y,Xia L,Lin K,Xu Y
Sun Dec 01 00:00:00 EST 2019
Targeting PLIN2/PLIN5-PPARγ: Sulforaphane Disturbs the Maturation of Lipid Droplets.
Molecular nutrition & food research
Tian S,Lei P,Teng C,Sun Y,Song X,Li B,Shan Y
Tue Oct 01 00:00:00 EDT 2019
JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.
Laboratory investigation; a journal of technical methods and pathology
Liu Q,Xie W,Wang Y,Chen S,Han J,Wang L,Gui P,Wu Q
Sun Dec 01 00:00:00 EST 2019
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Molecules (Basel, Switzerland)
Zhang C,Li C,Jia X,Wang K,Tu Y,Wang R,Liu K,Lu T,He C
Fri Mar 01 00:00:00 EST 2019
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Cells
Xu B,Lang LM,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Tue Jun 18 00:00:00 EDT 2019
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
The Journal of biological chemistry
Yang X,Wang G,Cao T,Zhang L,Ma Y,Jiang S,Teng X,Sun X
Fri Aug 30 00:00:00 EDT 2019
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
EBioMedicine
Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D
Tue Jan 01 00:00:00 EST 2019
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
EBioMedicine
Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D
Tue Jan 01 00:00:00 EST 2019
The Wnt/β-Catenin/LEF1 Pathway Promotes Cell Proliferation at Least in Part Through Direct Upregulation of miR-17-92 Cluster.
Frontiers in genetics
Mu F,Huang J,Xing T,Jing Y,Cui T,Guo Y,Yan X,Li H,Wang N
Wed Sep 30 00:00:00 EDT 2020
The protective effects of L-carnitine on myocardial ischaemia-reperfusion injury in patients with rheumatic valvular heart disease undergoing CPB surgery are associated with the suppression of NF-κB pathway and the activation of Nrf2 pathway.
Clinical and experimental pharmacology & physiology
Li M,Xu S,Geng Y,Sun L,Wang R,Yan Y,Wang H,Li Y,Yi Q,Zhang Y,Hao J,Deng C,Li W,Xue L
Fri Nov 01 00:00:00 EDT 2019
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Frontiers in immunology
Ruan J,Cao Y,Ling T,Li P,Wu S,Peng D,Wang Y,Jia X,Chen S,Xu A,Yuan S
Tue Nov 10 00:00:00 EST 2020
The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors.
PLoS pathogens
Cao P,Luo WW,Li C,Tong Z,Zheng ZQ,Zhou L,Xiong Y,Li S
Thu Aug 01 00:00:00 EDT 2019
Repositioning of niclosamide ethanolamine (NEN), an anthelmintic drug, for the treatment of lipotoxicity.
Free radical biology & medicine
Park JS,Lee YS,Lee DH,Bae SH
Sat Jun 01 00:00:00 EDT 2019
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Free radical biology & medicine
Li AL,Shen T,Wang T,Zhou MX,Wang B,Song JT,Zhang PL,Wang XL,Ren DM,Lou HX,Wang XN
Sun Sep 01 00:00:00 EDT 2019
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents.
Nature communications
Wang Z,Chen Z,Jiang Z,Luo P,Liu L,Huang Y,Wang H,Wang Y,Long L,Tan X,Liu D,Jin T,Wang Y,Wang Y,Liao F,Zhang C,Chen L,Gan Y,Liu Y,Yang F,Huang C,Miao H,Chen J,Cheng T,Fu X,Shi C
Mon Jun 10 00:00:00 EDT 2019
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
EBioMedicine
Shan H,Li T,Zhang L,Yang R,Li Y,Zhang M,Dong Y,Zhou Y,Xu C,Yang B,Liang H,Gao X,Shan H
Tue Jan 01 00:00:00 EST 2019
Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.
EBioMedicine
Shan H,Li T,Zhang L,Yang R,Li Y,Zhang M,Dong Y,Zhou Y,Xu C,Yang B,Liang H,Gao X,Shan H
Tue Jan 01 00:00:00 EST 2019
ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma.
Cell death & disease
Liang B,Chen R,Song S,Wang H,Sun G,Yang H,Jing W,Zhou X,Fu Z,Huang G,Zhao J
Mon Nov 04 00:00:00 EST 2019
Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane.
Theranostics
Xu X,Wang D,Zheng C,Gao B,Fan J,Cheng P,Liu B,Yang L,Luo Z
Mon Jun 29 00:00:00 EDT 2020
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Animals : an open access journal from MDPI
Xu B,Lang L,Li S,Yuan J,Wang J,Yang H,Lian S
Sat Sep 14 00:00:00 EDT 2019
Atsttrin reduces lipopolysaccharide-induced neuroinflammation by inhibiting the nuclear factor kappa B signaling pathway.
Neural regeneration research
Liu L,Qu Y,Liu Y,Zhao H,Ma HC,Noor AF,Ji CJ,Nie L,Si M,Cheng L
Fri Nov 01 00:00:00 EDT 2019
Knockdown of Golgi phosphoprotein 73 blocks the trafficking of matrix metalloproteinase-2 in hepatocellular carcinoma cells and inhibits cell invasion.
Journal of cellular and molecular medicine
Liu Y,Zhang X,Zhou S,Shi J,Xu Y,He J,Lin F,Wei A,Zhou L,Chen Z
Mon Apr 01 00:00:00 EDT 2019
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway.
Molecular carcinogenesis
Xing Y,Zhang Z,Chi F,Zhou Y,Ren S,Zhao Z,Zhu Y,Piao D
Tue Oct 01 00:00:00 EDT 2019
Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis.
Molecular therapy. Nucleic acids
Yan Y,Qin D,Hu B,Zhang C,Liu S,Wu D,Huang W,Huang X,Wang L,Chen X,Zhang L
Fri Jun 07 00:00:00 EDT 2019
Inhibition of DYRK1A-EGFR axis by p53-MDM2 cascade mediates the induction of cellular senescence.
Cell death & disease
Xu X,Liu Q,Zhang C,Ren S,Xu L,Zhao Z,Dou H,Li P,Zhang X,Gong Y,Shao C
Mon Mar 25 00:00:00 EDT 2019
A cellular model for Wilson's disease using patient-derived induced pluripotent stem cells revealed aberrant β-catenin pathway during osteogenesis.
Biochemical and biophysical research communications
Liu J,Cui Y,Shi L,Luan J,Zhou X,Han J
Tue May 28 00:00:00 EDT 2019
Type I collagen or gelatin stimulates mouse peritoneal macrophages to aggregate and produce pro-inflammatory molecules through upregulated ROS levels.
International immunopharmacology
Zhang X,Chen YR,Zhao YL,Liu WW,Hayashi T,Mizuno K,Hattori S,Fujisaki H,Ogura T,Onodera S,Ikejima T
Fri Nov 01 00:00:00 EDT 2019
YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis.
Cell reports
Zhou X,Li W,Wang S,Zhang P,Wang Q,Xiao J,Zhang C,Zheng X,Xu X,Xue S,Hui L,Ji H,Wei B,Wang H
Tue Apr 23 00:00:00 EDT 2019
SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury.
International immunopharmacology
Le K,Chibaatar Daliv E,Wu S,Qian F,Ali AI,Yu D,Guo Y
Tue Oct 01 00:00:00 EDT 2019
Paclitaxel alleviates monocrotaline-induced pulmonary arterial hypertension via inhibition of FoxO1-mediated autophagy.
Naunyn-Schmiedeberg's archives of pharmacology
Feng W,Wang J,Yan X,Zhai C,Shi W,Wang Q,Zhang Q,Li M
Wed May 01 00:00:00 EDT 2019
p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma.
American journal of cancer research
Yang PM,Hong YH,Hsu KC,Liu TP
Tue Sep 29 00:00:00 EDT 2020
Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury.
Journal of neurochemistry
Zhong Y,Chen J,Chen J,Chen Y,Li L,Xie Y
Tue Oct 01 00:00:00 EDT 2019
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 EDT 2019
TMEM18 inhibits osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells by inactivating β-catenin.
Experimental cell research
Zhang Y,Wang H,Yin T,Liu Y,Zhou W,Fan X,Wu L,Song C,Shao J,Yang T
Tue Oct 01 00:00:00 EDT 2019
Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels.
Cancer biology & medicine
Li N,Wang T,Li Z,Ye X,Deng B,Zhuo S,Yao P,Yang M,Mei H,Chen X,Zhu T,Chen S,Wang H,Wang J,Le Y
Wed May 01 00:00:00 EDT 2019
Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.
Oxidative medicine and cellular longevity
Qaed E,Wang J,Almoiliqy M,Song Y,Liu W,Chu P,Alademi S,Alademi M,Li H,Alshwmi M,Al-Azab M,Ahsan A,Mahdi S,Han G,Niu M,Ali A,Shopit A,Wang H,Li X,Qaid A,Ma X,Li T,Peng J,Ma J,Zhang J,Tang Z
Thu Jun 25 00:00:00 EDT 2020
P200 family protein IFI204 negatively regulates type I interferon responses by targeting IRF7 in nucleus.
PLoS pathogens
Cao L,Ji Y,Zeng L,Liu Q,Zhang Z,Guo S,Guo X,Tong Y,Zhao X,Li CM,Chen Y,Guo D
Tue Oct 01 00:00:00 EDT 2019
IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes.
Arthritis research & therapy
Wang F,Liu J,Chen X,Zheng X,Qu N,Zhang B,Xia C
Wed Jul 10 00:00:00 EDT 2019
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Journal of experimental & clinical cancer research : CR
Qin Z,Xiang C,Zhong F,Liu Y,Dong Q,Li K,Shi W,Ding C,Qin L,He F
Thu Apr 11 00:00:00 EDT 2019
Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells.
Frontiers in pharmacology
Palikhe S,Ohashi W,Sakamoto T,Hattori K,Kawakami M,Andoh T,Yamazaki H,Hattori Y
Tue Sep 29 00:00:00 EDT 2020
Diallyl sulfide treatment protects against acetaminophen-/carbon tetrachloride-induced acute liver injury by inhibiting oxidative stress, inflammation and apoptosis in mice.
Toxicology research
Li M,Wang S,Li X,Kou R,Wang Q,Wang X,Zhao N,Zeng T,Xie K
Tue Jan 01 00:00:00 EST 2019
LncRNA SNHG16 promotes epithelial- mesenchymal transition via down-regulation of DKK3 in gastric cancer.
Cancer biomarkers : section A of Disease markers
Zhou C,Zhao J,Liu J,Wei S,Xia Y,Xia W,Bi Y,Yan Z,Huang H
Fri Jun 12 00:00:00 EDT 2020
Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yap JLY,Tai YK,Fröhlich J,Fong CHH,Yin JN,Foo ZL,Ramanan S,Beyer C,Toh SJ,Casarosa M,Bharathy N,Kala MP,Egli M,Taneja R,Lee CN,Franco-Obregón A
Fri Nov 01 00:00:00 EDT 2019
Revealing Antidepressant Mechanisms of Baicalin in Hypothalamus Through Systems Approaches in Corticosterone- Induced Depressed Mice.
Frontiers in neuroscience
Zhang K,He M,Wang F,Zhang H,Li Y,Yang J,Wu C
Tue Sep 29 00:00:00 EDT 2020
Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway.
Journal of molecular neuroscience : MN
Wang Q,Hu J,Liu Y,Li J,Liu B,Li M,Lou S
Sun Sep 01 00:00:00 EDT 2019
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Molecular medicine reports
Yang L,Hong Q,Xu SG,Kuang XY,Di GH,Liu GY,Wu J,Shao ZM,Yu SJ
Fri Nov 01 00:00:00 EDT 2019
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Medical science monitor : international medical journal of experimental and clinical research
Yang Y,Chen S,Tao L,Gan S,Luo H,Xu Y,Shen X
Sat Jul 20 00:00:00 EDT 2019
Follicle-stimulating hormone promotes renal tubulointerstitial fibrosis in aging women via the AKT/GSK-3β/β-catenin pathway.
Aging cell
Zhang K,Kuang L,Xia F,Chen Y,Zhang W,Zhai H,Wang C,Wang N,Lu Y
Tue Oct 01 00:00:00 EDT 2019
A Subcellular Quantitative Proteomic Analysis of Herpes Simplex Virus Type 1-Infected HEK 293T Cells.
Molecules (Basel, Switzerland)
Wan W,Wang L,Chen X,Zhu S,Shang W,Xiao G,Zhang LK
Wed Nov 20 00:00:00 EST 2019
A hidden human proteome encoded by 'non-coding' genes.
Nucleic acids research
Lu S,Zhang J,Lian X,Sun L,Meng K,Chen Y,Sun Z,Yin X,Li Y,Zhao J,Wang T,Zhang G,He QY
Thu Sep 05 00:00:00 EDT 2019
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Food & function
Shu G,Qiu Y,Hao J,Fu Q,Deng X
Wed Oct 16 00:00:00 EDT 2019
MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model.
Cells
Yang J,Zhang L,Cao LL,Qi J,Li P,Wang XP,Sun XL
Fri Sep 13 00:00:00 EDT 2019
Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells.
Journal of experimental & clinical cancer research : CR
Zhang Q,Liu RX,Chan KW,Hu J,Zhang J,Wei L,Tan H,Yang X,Liu H
Fri Jul 19 00:00:00 EDT 2019
DYRK1A inhibition suppresses STAT3/EGFR/Met signalling and sensitizes EGFR wild-type NSCLC cells to AZD9291.
Journal of cellular and molecular medicine
Li YL,Ding K,Hu X,Wu LW,Zhou DM,Rao MJ,Lin NM,Zhang C
Fri Nov 01 00:00:00 EDT 2019
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Biomolecules
Xu B,Lang LM,Li SZ,Guo JR,Wang JF,Yang HM,Lian S
Fri Aug 30 00:00:00 EDT 2019
Geniposide ameliorated fluoxetine-suppressed neurite outgrowth in Neuro2a neuroblastoma cells.
Life sciences
Chen MK,Peng CC,Maner RS,Zulkefli ND,Huang SM,Hsieh CL
Sat Jun 01 00:00:00 EDT 2019
Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells.
Cells
Wang J,Li L,Wang J,Song L,Tan N,Wang Z
Sat Dec 07 00:00:00 EST 2019
Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs.
International journal of biological sciences
Su M,Wang P,Wang X,Zhang M,Wei S,Liu K,Han S,Han X,Deng Y,Shen L
Mon Apr 06 00:00:00 EDT 2020
Sodium ferulate protects against influenza virus infection by activation of the TLR7/9-MyD88-IRF7 signaling pathway and inhibition of the NF-κB signaling pathway.
Biochemical and biophysical research communications
Zhu Y,Shao Y,Qu X,Guo J,Yang J,Zhou Z,Wang S
Tue May 14 00:00:00 EDT 2019
Cytoplasmic SIRT1 inhibits cell migration and invasion by impeding epithelial-mesenchymal transition in ovarian carcinoma.
Molecular and cellular biochemistry
Yang T,Zhou R,Yu S,Yu S,Cui Z,Hu P,Liu J,Qiao Q,Zhang J
Sun Sep 01 00:00:00 EDT 2019
Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.
Biochimica et biophysica acta. Molecular cell research
Yang Q,Fan W,Zheng Z,Lin S,Liu C,Wang R,Li W,Zuo Y,Sun Y,Hu S,Chen M,Guo P,Pan J,Tian C,Zhu T,Diao C,Hao J,Yu W,Li L,Li Y,Guo W,Deng W,Wu X
Tue Oct 01 00:00:00 EDT 2019
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Journal of experimental & clinical cancer research : CR
Zhang W,Lu Y,Li X,Zhang J,Lin W,Zhang W,Zheng L,Li X
Tue Jul 09 00:00:00 EDT 2019
Arsenic trioxide inhibits angiogenesis in vitro and in vivo by upregulating FoxO3a.
Toxicology letters
Sun Z,Li M,Bai L,Fu J,Lu J,Wu M,Zhou C,Zhang Y,Wu Y
Tue Oct 15 00:00:00 EDT 2019
Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS.
Nature cell biology
Wang Y,Yuan S,Jia X,Ge Y,Ling T,Nie M,Lan X,Chen S,Xu A
Fri Nov 01 00:00:00 EDT 2019
Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes.
PloS one
Trajkovic K,Valdez C,Ysselstein D,Krainc D
Tue Nov 12 00:00:00 EST 2019
Ginsenoside Rk3 ameliorates high-fat-diet/streptozocin induced type 2 diabetes mellitus in mice via the AMPK/Akt signaling pathway.
Food & function
Liu Y,Deng J,Fan D
Wed May 22 00:00:00 EDT 2019
Leptin-Induced Angiogenesis of EA.Hy926 Endothelial Cells via the Akt and Wnt Signaling Pathways In Vitro and In Vivo.
Frontiers in pharmacology
Yu F,Fu R,Liu L,Wang X,Wu T,Shen W,Gui Z,Mo X,Fang B,Xia L
Tue Sep 29 00:00:00 EDT 2020
Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.
Chemico-biological interactions
Wu XY,Chen XM,Zhou MX,Hu HX,Zhang JZ,Wang XN,Ren DM,Lou HX,Shen T
Sun Sep 01 00:00:00 EDT 2019
Mechanisms of Aerobic Exercise Upregulating the Expression of Hippocampal Synaptic Plasticity-Associated Proteins in Diabetic Rats.
Neural plasticity
Li J,Liu Y,Liu B,Li F,Hu J,Wang Q,Li M,Lou S
Mon May 13 00:00:00 EDT 2019
Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1.
Nature
Li Y,Zhang Z,Chen J,Liu W,Lai W,Liu B,Li X,Liu L,Xu S,Dong Q,Wang M,Duan X,Tan J,Zheng Y,Zhang P,Fan G,Wong J,Xu GL,Wang Z,Wang H,Gao S,Zhu B
Sat Dec 01 00:00:00 EST 2018
The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors.
Immunity
Lian H,Zang R,Wei J,Ye W,Hu MM,Chen YD,Zhang XN,Guo Y,Lei CQ,Yang Q,Luo WW,Li S,Shu HB
Tue Sep 18 00:00:00 EDT 2018
PTEN-L promotes type I interferon responses and antiviral immunity.
Cellular & molecular immunology
Cao Y,Wang H,Yang L,Zhang Z,Li C,Yuan X,Bu L,Chen L,Chen Y,Li CM,Guo D
Mon Jan 01 00:00:00 EST 2018
PTEN-L promotes type I interferon responses and antiviral immunity.
Cellular & molecular immunology
Cao Y,Wang H,Yang L,Zhang Z,Li C,Yuan X,Bu L,Chen L,Chen Y,Li CM,Guo D
Mon Jan 01 00:00:00 EST 2018
Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.
The Journal of clinical investigation
Pariollaud M,Gibbs JE,Hopwood TW,Brown S,Begley N,Vonslow R,Poolman T,Guo B,Saer B,Jones DH,Tellam JP,Bresciani S,Tomkinson NC,Wojno-Picon J,Cooper AW,Daniels DA,Trump RP,Grant D,Zuercher W,Willson TM,MacDonald AS,Bolognese B,Podolin PL,Sanchez Y,Loudon AS,Ray DW
Fri Jun 01 00:00:00 EDT 2018
Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.
The Journal of clinical investigation
Pariollaud M,Gibbs JE,Hopwood TW,Brown S,Begley N,Vonslow R,Poolman T,Guo B,Saer B,Jones DH,Tellam JP,Bresciani S,Tomkinson NC,Wojno-Picon J,Cooper AW,Daniels DA,Trump RP,Grant D,Zuercher W,Willson TM,MacDonald AS,Bolognese B,Podolin PL,Sanchez Y,Loudon AS,Ray DW
Fri Jun 01 00:00:00 EDT 2018
TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.
Cancer research
Sang Y,Li Y,Song L,Alvarez AA,Zhang W,Lv D,Tang J,Liu F,Chang Z,Hatakeyama S,Hu B,Cheng SY,Feng H
Sun Apr 01 00:00:00 EDT 2018
TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.
Cancer research
Sang Y,Li Y,Song L,Alvarez AA,Zhang W,Lv D,Tang J,Liu F,Chang Z,Hatakeyama S,Hu B,Cheng SY,Feng H
Sun Apr 01 00:00:00 EDT 2018
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
Diabetologia
Qi X,Guo Y,Song Y,Yu C,Zhao L,Fang L,Kong D,Zhao J,Gao L
Tue May 01 00:00:00 EDT 2018
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice.
Diabetologia
Qi X,Guo Y,Song Y,Yu C,Zhao L,Fang L,Kong D,Zhao J,Gao L
Tue May 01 00:00:00 EDT 2018
Prostaglandin F2α Facilitates Hepatic Glucose Production Through CaMKIIγ/p38/FOXO1 Signaling Pathway in Fasting and Obesity.
Diabetes
Wang Y,Yan S,Xiao B,Zuo S,Zhang Q,Chen G,Yu Y,Chen D,Liu Q,Liu Y,Shen Y,Yu Y
Sat Sep 01 00:00:00 EDT 2018
Prostaglandin F2α Facilitates Hepatic Glucose Production Through CaMKIIγ/p38/FOXO1 Signaling Pathway in Fasting and Obesity.
Diabetes
Wang Y,Yan S,Xiao B,Zuo S,Zhang Q,Chen G,Yu Y,Chen D,Liu Q,Liu Y,Shen Y,Yu Y
Sat Sep 01 00:00:00 EDT 2018
Glycyrrhizin Protects Mice Against Experimental Autoimmune Encephalomyelitis by Inhibiting High-Mobility Group Box 1 (HMGB1) Expression and Neuronal HMGB1 Release.
Frontiers in immunology
Sun Y,Chen H,Dai J,Wan Z,Xiong P,Xu Y,Han Z,Chai W,Gong F,Zheng F
Wed Nov 20 00:00:00 EST 2019
Glycyrrhizin Protects Mice Against Experimental Autoimmune Encephalomyelitis by Inhibiting High-Mobility Group Box 1 (HMGB1) Expression and Neuronal HMGB1 Release.
Frontiers in immunology
Sun Y,Chen H,Dai J,Wan Z,Xiong P,Xu Y,Han Z,Chai W,Gong F,Zheng F
Wed Nov 20 00:00:00 EST 2019
An Immunosuppressive Tick Salivary Gland Protein DsCystatin Interferes With Toll-Like Receptor Signaling by Downregulating TRAF6.
Frontiers in immunology
Sun T,Wang F,Pan W,Wu Q,Wang J,Dai J
Fri Aug 09 00:00:00 EDT 2019
Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.
PLoS pathogens
Luo W,Zhang J,Liang L,Wang G,Li Q,Zhu P,Zhou Y,Li J,Zhao Y,Sun N,Huang S,Zhou C,Chang Y,Cui P,Chen P,Jiang Y,Deng G,Bu Z,Li C,Jiang L,Chen H
Mon Jan 01 00:00:00 EST 2018
Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.
PLoS pathogens
Luo W,Zhang J,Liang L,Wang G,Li Q,Zhu P,Zhou Y,Li J,Zhao Y,Sun N,Huang S,Zhou C,Chang Y,Cui P,Chen P,Jiang Y,Deng G,Bu Z,Li C,Jiang L,Chen H
Mon Jan 01 00:00:00 EST 2018
PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu P,Chen B,Gu Y,Liu Q
Sat Dec 01 00:00:00 EST 2018
PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu P,Chen B,Gu Y,Liu Q
Sat Dec 01 00:00:00 EST 2018
Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Liu X,Zhu Q,Zhang M,Yin T,Xu R,Xiao W,Wu J,Deng B,Gao X,Gong W,Lu G,Ding Y
Mon Oct 01 00:00:00 EDT 2018
Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Liu X,Zhu Q,Zhang M,Yin T,Xu R,Xiao W,Wu J,Deng B,Gao X,Gong W,Lu G,Ding Y
Mon Oct 01 00:00:00 EDT 2018
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Life sciences
Huang J,Chen S,Cai D,Bian D,Wang F
Fri Jun 15 00:00:00 EDT 2018
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Life sciences
Zhai C,Shi W,Feng W,Zhu Y,Wang J,Li S,Yan X,Wang Q,Zhang Q,Chai L,Li C,Liu P,Li M
Sat Sep 01 00:00:00 EDT 2018
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Life sciences
Zhai C,Shi W,Feng W,Zhu Y,Wang J,Li S,Yan X,Wang Q,Zhang Q,Chai L,Li C,Liu P,Li M
Sat Sep 01 00:00:00 EDT 2018
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
Life sciences
Shi W,Zhai C,Feng W,Wang J,Zhu Y,Li S,Wang Q,Zhang Q,Yan X,Chai L,Liu P,Chen Y,Li M
Mon Oct 01 00:00:00 EDT 2018
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
Life sciences
Shi W,Zhai C,Feng W,Wang J,Zhu Y,Li S,Wang Q,Zhang Q,Yan X,Chai L,Liu P,Chen Y,Li M
Mon Oct 01 00:00:00 EDT 2018
Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets.
Journal of lipid research
Nguyen A,Guedán A,Mousnier A,Swieboda D,Zhang Q,Horkai D,Le Novere N,Solari R,Wakelam MJO
Sat Sep 01 00:00:00 EDT 2018
Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets.
Journal of lipid research
Nguyen A,Guedán A,Mousnier A,Swieboda D,Zhang Q,Horkai D,Le Novere N,Solari R,Wakelam MJO
Sat Sep 01 00:00:00 EDT 2018
Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent.
Biochimica et biophysica acta. Molecular basis of disease
Alsousi AA,Igwe OJ
Thu Nov 01 00:00:00 EDT 2018
Sulforaphane Improves Abnormal Lipid Metabolism via Both ERS-Dependent XBP1/ACC &SCD1 and ERS-Independent SREBP/FAS Pathways.
Molecular nutrition & food research
Tian S,Li B,Lei P,Yang X,Zhang X,Bao Y,Shan Y
Thu Mar 01 00:00:00 EST 2018
Sulforaphane Improves Abnormal Lipid Metabolism via Both ERS-Dependent XBP1/ACC &SCD1 and ERS-Independent SREBP/FAS Pathways.
Molecular nutrition & food research
Tian S,Li B,Lei P,Yang X,Zhang X,Bao Y,Shan Y
Thu Mar 01 00:00:00 EST 2018
Sulforaphane Improves Abnormal Lipid Metabolism via Both ERS-Dependent XBP1/ACC &SCD1 and ERS-Independent SREBP/FAS Pathways.
Molecular nutrition & food research
Tian S,Li B,Lei P,Yang X,Zhang X,Bao Y,Shan Y
Thu Mar 01 00:00:00 EST 2018
Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.
Journal of virology
Wu CC,Jiang X,Wang XZ,Liu XJ,Li XJ,Yang B,Ye HQ,Harwardt T,Jiang M,Xia HM,Wang W,Britt WJ,Paulus C,Nevels M,Luo MH
Sat Sep 01 00:00:00 EDT 2018
Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.
Journal of virology
Wu CC,Jiang X,Wang XZ,Liu XJ,Li XJ,Yang B,Ye HQ,Harwardt T,Jiang M,Xia HM,Wang W,Britt WJ,Paulus C,Nevels M,Luo MH
Sat Sep 01 00:00:00 EDT 2018
Activation of peroxisome proliferation-activated receptor-γ inhibits transforming growth factor-β1-induced airway smooth muscle cell proliferation by suppressing Smad-miR-21 signaling.
Journal of cellular physiology
Liu L,Pan Y,Zhai C,Zhu Y,Ke R,Shi W,Wang J,Yan X,Su X,Song Y,Gao L,Li M
Mon Jan 01 00:00:00 EST 2018
Activation of peroxisome proliferation-activated receptor-γ inhibits transforming growth factor-β1-induced airway smooth muscle cell proliferation by suppressing Smad-miR-21 signaling.
Journal of cellular physiology
Liu L,Pan Y,Zhai C,Zhu Y,Ke R,Shi W,Wang J,Yan X,Su X,Song Y,Gao L,Li M
Mon Jan 01 00:00:00 EST 2018
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Journal of cellular physiology
Song Y,Gao L,Tang Z,Li H,Sun B,Chu P,Qaed E,Ma X,Peng J,Wang S,Hu M,Tang Z
Mon Jan 01 00:00:00 EST 2018
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Journal of cellular physiology
Song Y,Gao L,Tang Z,Li H,Sun B,Chu P,Qaed E,Ma X,Peng J,Wang S,Hu M,Tang Z
Mon Jan 01 00:00:00 EST 2018
Natural product toosendanin reverses the resistance of human breast cancer cells to adriamycin as a novel PI3K inhibitor.
Biochemical pharmacology
Kai W,Yating S,Lin M,Kaiyong Y,Baojin H,Wu Y,Fangzhou Y,Yan C
Fri Jun 01 00:00:00 EDT 2018
Natural product toosendanin reverses the resistance of human breast cancer cells to adriamycin as a novel PI3K inhibitor.
Biochemical pharmacology
Kai W,Yating S,Lin M,Kaiyong Y,Baojin H,Wu Y,Fangzhou Y,Yan C
Fri Jun 01 00:00:00 EDT 2018
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang Y,Qi Q,Wang Y,Shi Y,Yang W,Cen Y,Zhu E,Li X,Chen D,Wang B
Fri Jun 01 00:00:00 EDT 2018
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yang Y,Qi Q,Wang Y,Shi Y,Yang W,Cen Y,Zhu E,Li X,Chen D,Wang B
Fri Jun 01 00:00:00 EDT 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 EST 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 EST 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 EST 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 EST 2018
Stattic inhibits RANKL-mediated osteoclastogenesis by suppressing activation of STAT3 and NF-κB pathways.
International immunopharmacology
Li CH,Xu LL,Jian LL,Yu RH,Zhao JX,Sun L,Du GH,Liu XY
Tue May 01 00:00:00 EDT 2018
Stattic inhibits RANKL-mediated osteoclastogenesis by suppressing activation of STAT3 and NF-κB pathways.
International immunopharmacology
Li CH,Xu LL,Jian LL,Yu RH,Zhao JX,Sun L,Du GH,Liu XY
Tue May 01 00:00:00 EDT 2018
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
The international journal of biochemistry & cell biology
Ke M,Dong J,Wang Y,Zhang J,Zhang M,Wu Z,Lv Y,Wu R
Wed Aug 01 00:00:00 EDT 2018
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
The international journal of biochemistry & cell biology
Ke M,Dong J,Wang Y,Zhang J,Zhang M,Wu Z,Lv Y,Wu R
Wed Aug 01 00:00:00 EDT 2018
The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation.
The FEBS journal
Yan X,Lu J,Zou X,Zhang S,Cui Y,Zhou L,Liu F,Shan A,Lu J,Zheng M,Feng B,Zhang Y
Wed Aug 01 00:00:00 EDT 2018
The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation.
The FEBS journal
Yan X,Lu J,Zou X,Zhang S,Cui Y,Zhou L,Liu F,Shan A,Lu J,Zheng M,Feng B,Zhang Y
Wed Aug 01 00:00:00 EDT 2018
The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation.
The FEBS journal
Yan X,Lu J,Zou X,Zhang S,Cui Y,Zhou L,Liu F,Shan A,Lu J,Zheng M,Feng B,Zhang Y
Wed Aug 01 00:00:00 EDT 2018
The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation.
The FEBS journal
Yan X,Lu J,Zou X,Zhang S,Cui Y,Zhou L,Liu F,Shan A,Lu J,Zheng M,Feng B,Zhang Y
Wed Aug 01 00:00:00 EDT 2018
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Laboratory investigation; a journal of technical methods and pathology
Zhang S,Xie C,Li H,Zhang K,Li J,Wang X,Yin Z
Sun Jul 01 00:00:00 EDT 2018
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Laboratory investigation; a journal of technical methods and pathology
Zhang S,Xie C,Li H,Zhang K,Li J,Wang X,Yin Z
Sun Jul 01 00:00:00 EDT 2018
Astrocyte elevated gene-1 participates in the production of pro-inflammatory cytokines in dental pulp cells via NF-κB signalling pathway.
International endodontic journal
Wu H,He M,Yang R,Zuo Y,Bian Z
Mon Oct 01 00:00:00 EDT 2018
Astrocyte elevated gene-1 participates in the production of pro-inflammatory cytokines in dental pulp cells via NF-κB signalling pathway.
International endodontic journal
Wu H,He M,Yang R,Zuo Y,Bian Z
Mon Oct 01 00:00:00 EDT 2018
Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells.
Mediators of inflammation
Cui S,Men L,Li Y,Zhong Y,Yu S,Li F,Du J
Mon Oct 01 00:00:00 EDT 2018
Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells.
Mediators of inflammation
Cui S,Men L,Li Y,Zhong Y,Yu S,Li F,Du J
Mon Oct 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Journal of cellular biochemistry
Zhang X,Li X,Fang J,Hou X,Fang H,Guo F,Li F,Chen A,Huang S
Thu Nov 01 00:00:00 EDT 2018
Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats.
Toxicology and applied pharmacology
Shi X,Zhao Y,Ding C,Wang Z,Ji A,Li Z,Feng D,Li Y,Gao D,Zhou J,Tian X,Yao J
Sun Jul 01 00:00:00 EDT 2018
Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats.
Toxicology and applied pharmacology
Shi X,Zhao Y,Ding C,Wang Z,Ji A,Li Z,Feng D,Li Y,Gao D,Zhou J,Tian X,Yao J
Sun Jul 01 00:00:00 EDT 2018
PARP1 interacts with STAT3 and retains active phosphorylated-STAT3 in nucleus during pathological myocardial hypertrophy.
Molecular and cellular endocrinology
Wang L,Li Z,Tan Y,Li Q,Yang H,Wang P,Lu J,Liu P
Mon Oct 15 00:00:00 EDT 2018
PARP1 interacts with STAT3 and retains active phosphorylated-STAT3 in nucleus during pathological myocardial hypertrophy.
Molecular and cellular endocrinology
Wang L,Li Z,Tan Y,Li Q,Yang H,Wang P,Lu J,Liu P
Mon Oct 15 00:00:00 EDT 2018
Calpain and JNK pathways participate in isoflurane - induced nucleus translocation of apoptosis-inducing factor in the brain of neonatal rats.
Toxicology letters
Han X,Liu C,Zhang K,Guo M,Shen Z,Liu Y,Zuo Z,Cao M,Li Y
Thu Mar 15 00:00:00 EDT 2018
Calpain and JNK pathways participate in isoflurane - induced nucleus translocation of apoptosis-inducing factor in the brain of neonatal rats.
Toxicology letters
Han X,Liu C,Zhang K,Guo M,Shen Z,Liu Y,Zuo Z,Cao M,Li Y
Thu Mar 15 00:00:00 EDT 2018
IRF1 up-regulates isg15 gene expression in dsRNA stimulation or CSFV infection by targeting nucleotides -487 to -325 in the 5' flanking region.
Molecular immunology
Li XQ,Li XN,Liang JJ,Cai XB,Tao Q,Li YX,Qin Q,Xu SP,Luo TR
Thu Feb 01 00:00:00 EST 2018
IRF1 up-regulates isg15 gene expression in dsRNA stimulation or CSFV infection by targeting nucleotides -487 to -325 in the 5' flanking region.
Molecular immunology
Li XQ,Li XN,Liang JJ,Cai XB,Tao Q,Li YX,Qin Q,Xu SP,Luo TR
Thu Feb 01 00:00:00 EST 2018
Sub-lethal ultraviolet B irradiation and Poly I:C treatment synergistically induced apoptosis of HaCaT cells through NF-κB pathway.
Molecular immunology
Otkur W,Liu W,Wang J,Jia X,Huang D,Wang F,Hayashi T,Tashiro SI,Onodera S,Ikejima T
Sun Jul 01 00:00:00 EDT 2018
Sub-lethal ultraviolet B irradiation and Poly I:C treatment synergistically induced apoptosis of HaCaT cells through NF-κB pathway.
Molecular immunology
Otkur W,Liu W,Wang J,Jia X,Huang D,Wang F,Hayashi T,Tashiro SI,Onodera S,Ikejima T
Sun Jul 01 00:00:00 EDT 2018
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Chemical research in toxicology
Liu Z,Dong W,Yang B,Peng L,Xia X,Pu L,Zhang N,Song E,Song Y
Mon Nov 19 00:00:00 EST 2018
Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.
Chemical research in toxicology
Liu Z,Dong W,Yang B,Peng L,Xia X,Pu L,Zhang N,Song E,Song Y
Mon Nov 19 00:00:00 EST 2018
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Chemical research in toxicology
Wang Y,Wang Y,Liu Z,Dong W,Yang B,Xia X,Song E,Song Y
Mon Sep 17 00:00:00 EDT 2018
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Chemical research in toxicology
Wang Y,Wang Y,Liu Z,Dong W,Yang B,Xia X,Song E,Song Y
Mon Sep 17 00:00:00 EDT 2018
Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
Gene
Hu M,Liu L,Yao W
Sat Dec 15 00:00:00 EST 2018
Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
Gene
Hu M,Liu L,Yao W
Sat Dec 15 00:00:00 EST 2018
Folic acid supplementation repressed hypoxia-induced inflammatory response via ROS and JAK2/STAT3 pathway in human promyelomonocytic cells.
Nutrition research (New York, N.Y.)
Ma J,Zhen X,Huang X,Jiang X
Tue May 01 00:00:00 EDT 2018
Folic acid supplementation repressed hypoxia-induced inflammatory response via ROS and JAK2/STAT3 pathway in human promyelomonocytic cells.
Nutrition research (New York, N.Y.)
Ma J,Zhen X,Huang X,Jiang X
Tue May 01 00:00:00 EDT 2018
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Brain research bulletin
Li F,Liu BB,Cai M,Li JJ,Lou SJ
Fri Jun 01 00:00:00 EDT 2018
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Brain research bulletin
Li F,Liu BB,Cai M,Li JJ,Lou SJ
Fri Jun 01 00:00:00 EDT 2018
Neuroprotective effects of metformin on traumatic brain injury in rats associated with NF-κB and MAPK signaling pathway.
Brain research bulletin
Tao L,Li D,Liu H,Jiang F,Xu Y,Cao Y,Gao R,Chen G
Fri Jun 01 00:00:00 EDT 2018
Neuroprotective effects of metformin on traumatic brain injury in rats associated with NF-κB and MAPK signaling pathway.
Brain research bulletin
Tao L,Li D,Liu H,Jiang F,Xu Y,Cao Y,Gao R,Chen G
Fri Jun 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Discovery of natural flavonoids as activators of Nrf2-mediated defense system: Structure-activity relationship and inhibition of intracellular oxidative insults.
Bioorganic & medicinal chemistry
Li YR,Li GH,Zhou MX,Xiang L,Ren DM,Lou HX,Wang XN,Shen T
Mon Oct 01 00:00:00 EDT 2018
Discovery of natural flavonoids as activators of Nrf2-mediated defense system: Structure-activity relationship and inhibition of intracellular oxidative insults.
Bioorganic & medicinal chemistry
Li YR,Li GH,Zhou MX,Xiang L,Ren DM,Lou HX,Wang XN,Shen T
Mon Oct 01 00:00:00 EDT 2018
Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury.
Behavioural brain research
Hou Y,Wang Y,He Q,Li L,Xie H,Zhao Y,Zhao J
Mon Jan 15 00:00:00 EST 2018
Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury.
Behavioural brain research
Hou Y,Wang Y,He Q,Li L,Xie H,Zhao Y,Zhao J
Mon Jan 15 00:00:00 EST 2018
Dynamic changes of proteasome and protective effect of bortezomib, a proteasome inhibitor, in mice with acute pancreatitis.
Biochemical and biophysical research communications
Zhu Q,Lin X,Liu X,Hou T,Zhang M,Wang N,Chen W,Lu G,Gong W,Ding Y,Xiao W
Sat Oct 20 00:00:00 EDT 2018
Dynamic changes of proteasome and protective effect of bortezomib, a proteasome inhibitor, in mice with acute pancreatitis.
Biochemical and biophysical research communications
Zhu Q,Lin X,Liu X,Hou T,Zhang M,Wang N,Chen W,Lu G,Gong W,Ding Y,Xiao W
Sat Oct 20 00:00:00 EDT 2018
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Biochemical and biophysical research communications
Zhang LM,Zhang J,Zhang Y,Wang L,Fei C,Yi ZW,Dong L
Fri Nov 02 00:00:00 EDT 2018
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Biochemical and biophysical research communications
Zhang LM,Zhang J,Zhang Y,Wang L,Fei C,Yi ZW,Dong L
Fri Nov 02 00:00:00 EDT 2018
Fam83h mutation inhibits the mineralization in ameloblasts by activating Wnt/β-catenin signaling pathway.
Biochemical and biophysical research communications
Yang M,Huang W,Yang F,Zhang T,Wang C,Song Y
Mon Jun 18 00:00:00 EDT 2018
Fam83h mutation inhibits the mineralization in ameloblasts by activating Wnt/β-catenin signaling pathway.
Biochemical and biophysical research communications
Yang M,Huang W,Yang F,Zhang T,Wang C,Song Y
Mon Jun 18 00:00:00 EDT 2018
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Biochemical and biophysical research communications
Liu L,Shen Y,Zhu X,Lv R,Li S,Zhang Z,Shi YG,Tan L
Sat Oct 20 00:00:00 EDT 2018
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Biochemical and biophysical research communications
Liu L,Shen Y,Zhu X,Lv R,Li S,Zhang Z,Shi YG,Tan L
Sat Oct 20 00:00:00 EDT 2018
Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.
Biochemical and biophysical research communications
Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y
Mon Jan 01 00:00:00 EST 2018
Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.
Biochemical and biophysical research communications
Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y
Mon Jan 01 00:00:00 EST 2018
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
Biochemical and biophysical research communications
Xu Q,Cui Y,Luan J,Zhou X,Li H,Han J
Sun Mar 25 00:00:00 EDT 2018
Exosomes from C2C12 myoblasts enhance osteogenic differentiation of MC3T3-E1 pre-osteoblasts by delivering miR-27a-3p.
Biochemical and biophysical research communications
Xu Q,Cui Y,Luan J,Zhou X,Li H,Han J
Sun Mar 25 00:00:00 EDT 2018
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Fang X,Liu Y,Lu J,Hong H,Yuan J,Zhang Y,Wang P,Liu P,Ye J
Sat Dec 01 00:00:00 EST 2018
Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Fang X,Liu Y,Lu J,Hong H,Yuan J,Zhang Y,Wang P,Liu P,Ye J
Sat Dec 01 00:00:00 EST 2018
Histone methylation regulates Hif-1 signaling cascade in activation of hepatic stellate cells.
FEBS open bio
Hong F,Wan L,Liu J,Huang K,Xiao Z,Zhang Y,Shi C
Thu Mar 01 00:00:00 EST 2018
Histone methylation regulates Hif-1 signaling cascade in activation of hepatic stellate cells.
FEBS open bio
Hong F,Wan L,Liu J,Huang K,Xiao Z,Zhang Y,Shi C
Thu Mar 01 00:00:00 EST 2018
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Medical science monitor : international medical journal of experimental and clinical research
Wang C,Luo H,Xu Y,Tao L,Chang C,Shen X
Fri Oct 26 00:00:00 EDT 2018
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Medical science monitor : international medical journal of experimental and clinical research
Wang C,Luo H,Xu Y,Tao L,Chang C,Shen X
Fri Oct 26 00:00:00 EDT 2018
Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway.
Lipids in health and disease
Shen Z,Ma Y,Ji Z,Hao Y,Yan X,Zhong Y,Tang X,Ren W
Fri Feb 09 00:00:00 EST 2018
Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway.
Lipids in health and disease
Shen Z,Ma Y,Ji Z,Hao Y,Yan X,Zhong Y,Tang X,Ren W
Fri Feb 09 00:00:00 EST 2018
Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting β-catenin signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang J,Qi H,Zhang X,Si W,Xu F,Hou T,Zhou H,Wang A,Li G,Liu Y,Fang Y,Piao HL,Liang X
Sat Dec 01 00:00:00 EST 2018
TRPV2-induced Ca2+-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma.
Cell communication and signaling : CCS
Bai H,Zhu H,Yan Q,Shen X,Lu X,Wang J,Li J,Chen L
Tue Oct 16 00:00:00 EDT 2018
TRPV2-induced Ca2+-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma.
Cell communication and signaling : CCS
Bai H,Zhu H,Yan Q,Shen X,Lu X,Wang J,Li J,Chen L
Tue Oct 16 00:00:00 EDT 2018
The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion.
Cell death & disease
Li T,Yi L,Hai L,Ma H,Tao Z,Zhang C,Abeysekera IR,Zhao K,Yang Y,Wang W,Liu B,Yu S,Tong L,Liu P,Zhu M,Ren B,Lin Y,Zhang K,Cheng C,Huang Y,Yang X
Tue Feb 20 00:00:00 EST 2018
The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion.
Cell death & disease
Li T,Yi L,Hai L,Ma H,Tao Z,Zhang C,Abeysekera IR,Zhao K,Yang Y,Wang W,Liu B,Yu S,Tong L,Liu P,Zhu M,Ren B,Lin Y,Zhang K,Cheng C,Huang Y,Yang X
Tue Feb 20 00:00:00 EST 2018
Overexpression of β-Catenin Decreases the Radiosensitivity of Human Nasopharyngeal Carcinoma CNE-2 Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
He H,Lin K,Su Y,Lin S,Zou C,Pan J,Zhou Y,Chen C
Mon Nov 26 00:00:00 EST 2018
Overexpression of β-Catenin Decreases the Radiosensitivity of Human Nasopharyngeal Carcinoma CNE-2 Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
He H,Lin K,Su Y,Lin S,Zou C,Pan J,Zhou Y,Chen C
Mon Nov 26 00:00:00 EST 2018
PDK1 inhibitor GSK2334470 synergizes with proteasome inhibitor MG‑132 in multiple myeloma cells by inhibiting full AKT activity and increasing nuclear accumulation of the PTEN protein.
Oncology reports
Zhang J,Yang C,Zhou F,Chen X
Fri Jun 01 00:00:00 EDT 2018
Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nature communications
Harada A,Maehara K,Ono Y,Taguchi H,Yoshioka K,Kitajima Y,Xie Y,Sato Y,Iwasaki T,Nogami J,Okada S,Komatsu T,Semba Y,Takemoto T,Kimura H,Kurumizaka H,Ohkawa Y
Wed Apr 11 00:00:00 EDT 2018
Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nature communications
Harada A,Maehara K,Ono Y,Taguchi H,Yoshioka K,Kitajima Y,Xie Y,Sato Y,Iwasaki T,Nogami J,Okada S,Komatsu T,Semba Y,Takemoto T,Kimura H,Kurumizaka H,Ohkawa Y
Wed Apr 11 00:00:00 EDT 2018
OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos.
Cell death & disease
Wang R,Li C,Qiao P,Xue Y,Zheng X,Chen H,Zeng X,Liu W,Boldogh I,Ba X
Thu May 24 00:00:00 EDT 2018
OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos.
Cell death & disease
Wang R,Li C,Qiao P,Xue Y,Zheng X,Chen H,Zeng X,Liu W,Boldogh I,Ba X
Thu May 24 00:00:00 EDT 2018
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
Cell death & disease
Zhang Y,Li A,Shi J,Fang Y,Gu C,Cai J,Lin C,Zhao L,Liu S
Tue Jul 03 00:00:00 EDT 2018
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
Cell death & disease
Zhang Y,Li A,Shi J,Fang Y,Gu C,Cai J,Lin C,Zhao L,Liu S
Tue Jul 03 00:00:00 EDT 2018
Comparison of the Effects and Inhibitory Pathways of the Constituents from Gynostemma pentaphyllum against LPS-Induced Inflammatory Response.
Journal of agricultural and food chemistry
Shen CY,Jiang JG,Shi MM,Yang HL,Wei H,Zhu W
Wed Oct 31 00:00:00 EDT 2018
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1α.
Cancer medicine
Chen X,Wu L,Li D,Xu Y,Zhang L,Niu K,Kong R,Gu J,Xu Z,Chen Z,Sun J
Wed Aug 01 00:00:00 EDT 2018
Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1α.
Cancer medicine
Chen X,Wu L,Li D,Xu Y,Zhang L,Niu K,Kong R,Gu J,Xu Z,Chen Z,Sun J
Wed Aug 01 00:00:00 EDT 2018
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.
eLife
Yoney A,Etoc F,Ruzo A,Carroll T,Metzger JJ,Martyn I,Li S,Kirst C,Siggia ED,Brivanlou AH
Fri Oct 12 00:00:00 EDT 2018
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.
eLife
Yoney A,Etoc F,Ruzo A,Carroll T,Metzger JJ,Martyn I,Li S,Kirst C,Siggia ED,Brivanlou AH
Fri Oct 12 00:00:00 EDT 2018
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Molecules (Basel, Switzerland)
Tian YS,Chen KC,Zulkefli ND,Maner RS,Hsieh CL
Fri Dec 14 00:00:00 EST 2018
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Molecules (Basel, Switzerland)
Tian YS,Chen KC,Zulkefli ND,Maner RS,Hsieh CL
Fri Dec 14 00:00:00 EST 2018
Constitutive Activation of β-Catenin in Differentiated Osteoclasts Induces Bone Loss in Mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Sui X,Deng S,Liu M,Fan L,Wang Y,Xu H,Sun Y,Kishen A,Zhang Q
Mon Sep 10 00:00:00 EDT 2018
An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.
Scientific reports
Galarza Torre A,Shaw JE,Wood A,Gilbert HTJ,Dobre O,Genever P,Brennan K,Richardson SM,Swift J
Tue Jun 12 00:00:00 EDT 2018
An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.
Scientific reports
Galarza Torre A,Shaw JE,Wood A,Gilbert HTJ,Dobre O,Genever P,Brennan K,Richardson SM,Swift J
Tue Jun 12 00:00:00 EDT 2018
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1.
Scientific reports
Wang H,Chen Y,Guo J,Shan T,Deng K,Chen J,Cai L,Zhou H,Zhao Q,Jin S,Xia J
Fri May 04 00:00:00 EDT 2018
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1.
Scientific reports
Wang H,Chen Y,Guo J,Shan T,Deng K,Chen J,Cai L,Zhou H,Zhao Q,Jin S,Xia J
Fri May 04 00:00:00 EDT 2018
LINC01016 promotes the malignant phenotype of endometrial cancer cells by regulating the miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis.
Cell death & disease
Pan X,Li D,Huo J,Kong F,Yang H,Ma X
Wed Feb 21 00:00:00 EST 2018
LINC01016 promotes the malignant phenotype of endometrial cancer cells by regulating the miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis.
Cell death & disease
Pan X,Li D,Huo J,Kong F,Yang H,Ma X
Wed Feb 21 00:00:00 EST 2018
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Chemical research in toxicology
Dong W,Yang B,Wang Y,Yuan J,Fan Y,Song E,Song Y
Mon Nov 19 00:00:00 EST 2018
Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway.
Molecules (Basel, Switzerland)
Li L,Huang W,Wang S,Sun K,Zhang W,Ding Y,Zhang L,Tumen B,Ji L,Liu C
Tue Aug 14 00:00:00 EDT 2018
Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway.
Molecules (Basel, Switzerland)
Li L,Huang W,Wang S,Sun K,Zhang W,Ding Y,Zhang L,Tumen B,Ji L,Liu C
Tue Aug 14 00:00:00 EDT 2018
The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response.
The Journal of biological chemistry
Lellahi SM,Rosenlund IA,Hedberg A,Kiær LT,Mikkola I,Knutsen E,Perander M
Fri Dec 07 00:00:00 EST 2018
The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response.
The Journal of biological chemistry
Lellahi SM,Rosenlund IA,Hedberg A,Kiær LT,Mikkola I,Knutsen E,Perander M
Fri Dec 07 00:00:00 EST 2018
IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3.
Cellular & molecular immunology
Jiang LQ,Xia T,Hu YH,Sun MS,Yan S,Lei CQ,Shu HB,Guo JH,Liu Y
Sat Sep 01 00:00:00 EDT 2018
Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining.
Nature cell biology
Ly P,Teitz LS,Kim DH,Shoshani O,Skaletsky H,Fachinetti D,Page DC,Cleveland DW
Sun Jan 01 00:00:00 EST 2017
Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining.
Nature cell biology
Ly P,Teitz LS,Kim DH,Shoshani O,Skaletsky H,Fachinetti D,Page DC,Cleveland DW
Sun Jan 01 00:00:00 EST 2017
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport.
Neuron
Gasset-Rosa F,Chillon-Marinas C,Goginashvili A,Atwal RS,Artates JW,Tabet R,Wheeler VC,Bang AG,Cleveland DW,Lagier-Tourenne C
Wed Apr 05 00:00:00 EDT 2017
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport.
Neuron
Gasset-Rosa F,Chillon-Marinas C,Goginashvili A,Atwal RS,Artates JW,Tabet R,Wheeler VC,Bang AG,Cleveland DW,Lagier-Tourenne C
Wed Apr 05 00:00:00 EDT 2017
E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway.
Arteriosclerosis, thrombosis, and vascular biology
Chen D,Tang J,Wan Q,Zhang J,Wang K,Shen Y,Yu Y
Mon May 01 00:00:00 EDT 2017
E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway.
Arteriosclerosis, thrombosis, and vascular biology
Chen D,Tang J,Wan Q,Zhang J,Wang K,Shen Y,Yu Y
Mon May 01 00:00:00 EDT 2017
Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.
Oncogene
Ye J,Wei X,Shang Y,Pan Q,Yang M,Tian Y,He Y,Peng Z,Chen L,Chen W,Wang R
Thu Nov 16 00:00:00 EST 2017
Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.
Oncogene
Ye J,Wei X,Shang Y,Pan Q,Yang M,Tian Y,He Y,Peng Z,Chen L,Chen W,Wang R
Thu Nov 16 00:00:00 EST 2017
Mitochondrial control of apoptosis through modulation of cardiolipin oxidation in hepatocellular carcinoma: A novel link between oxidative stress and cancer.
Free radical biology & medicine
Zhong H,Xiao M,Zarkovic K,Zhu M,Sa R,Lu J,Tao Y,Chen Q,Xia L,Cheng S,Waeg G,Zarkovic N,Yin H
Sun Jan 01 00:00:00 EST 2017
Mitochondrial control of apoptosis through modulation of cardiolipin oxidation in hepatocellular carcinoma: A novel link between oxidative stress and cancer.
Free radical biology & medicine
Zhong H,Xiao M,Zarkovic K,Zhu M,Sa R,Lu J,Tao Y,Chen Q,Xia L,Cheng S,Waeg G,Zarkovic N,Yin H
Sun Jan 01 00:00:00 EST 2017
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
The Journal of cell biology
Qu J,Sun W,Zhong J,Lv H,Zhu M,Xu J,Jin N,Xie Z,Tan M,Lin SH,Geng M,Ding J,Huang M
Wed Feb 01 00:00:00 EST 2017
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
The Journal of cell biology
Qu J,Sun W,Zhong J,Lv H,Zhu M,Xu J,Jin N,Xie Z,Tan M,Lin SH,Geng M,Ding J,Huang M
Wed Feb 01 00:00:00 EST 2017
Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
The Journal of infectious diseases
Xie J,Long X,Gao L,Chen S,Zhao K,Li W,Zhou N,Zang N,Deng Y,Ren L,Wang L,Luo Z,Tu W,Zhao X,Fu Z,Xie X,Liu E
Wed Dec 27 00:00:00 EST 2017
Respiratory Syncytial Virus Nonstructural Protein 1 Blocks Glucocorticoid Receptor Nuclear Translocation by Targeting IPO13 and May Account for Glucocorticoid Insensitivity.
The Journal of infectious diseases
Xie J,Long X,Gao L,Chen S,Zhao K,Li W,Zhou N,Zang N,Deng Y,Ren L,Wang L,Luo Z,Tu W,Zhao X,Fu Z,Xie X,Liu E
Wed Dec 27 00:00:00 EST 2017
Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu YR,Ma H,Zou ZY,He K,Xiao YB,Wang Y,Feng M,Ye XL,Li XG
Sun Jan 01 00:00:00 EST 2017
Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu YR,Ma H,Zou ZY,He K,Xiao YB,Wang Y,Feng M,Ye XL,Li XG
Sun Jan 01 00:00:00 EST 2017
Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication.
Journal of virology
Guedán A,Swieboda D,Charles M,Toussaint M,Johnston SL,Asfor A,Panjwani A,Tuthill TJ,Danahay H,Raynham T,Mousnier A,Solari R
Mon May 01 00:00:00 EDT 2017
Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication.
Journal of virology
Guedán A,Swieboda D,Charles M,Toussaint M,Johnston SL,Asfor A,Panjwani A,Tuthill TJ,Danahay H,Raynham T,Mousnier A,Solari R
Mon May 01 00:00:00 EDT 2017
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Frontiers in molecular neuroscience
Song Z,Shah SZA,Yang W,Dong H,Yang L,Zhou X,Zhao D
Wed Sep 30 00:00:00 EDT 2020
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Frontiers in molecular neuroscience
Song Z,Shah SZA,Yang W,Dong H,Yang L,Zhou X,Zhao D
Wed Sep 30 00:00:00 EDT 2020
Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ.
American journal of cancer research
Wang J,Yu Z,Wang C,Tian X,Huo X,Wang Y,Sun C,Feng L,Ma J,Zhang B,Yang Q,Ma X,Xu Y
Thu Apr 01 00:00:00 EDT 2021
Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ.
American journal of cancer research
Wang J,Yu Z,Wang C,Tian X,Huo X,Wang Y,Sun C,Feng L,Ma J,Zhang B,Yang Q,Ma X,Xu Y
Thu Apr 01 00:00:00 EDT 2021
Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway.
International journal of oncology
Shrestha S,Zhu J,Wang Q,Du X,Liu F,Jiang J,Song J,Xing J,Sun D,Hou Q,Peng Y,Zhao J,Sun X,Song X
Sun Oct 01 00:00:00 EDT 2017
Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway.
International journal of oncology
Shrestha S,Zhu J,Wang Q,Du X,Liu F,Jiang J,Song J,Xing J,Sun D,Hou Q,Peng Y,Zhao J,Sun X,Song X
Sun Oct 01 00:00:00 EDT 2017
A small-molecule inhibitor of NF-κB-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ren X,Li X,Jia L,Chen D,Hou H,Rui L,Zhao Y,Chen Z
Wed Feb 01 00:00:00 EST 2017
A small-molecule inhibitor of NF-κB-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ren X,Li X,Jia L,Chen D,Hou H,Rui L,Zhao Y,Chen Z
Wed Feb 01 00:00:00 EST 2017
Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lu Y,Wan J,Yang Z,Lei X,Niu Q,Jiang L,Passtoors WM,Zang A,Fraering PC,Wu F
Sat Apr 01 00:00:00 EDT 2017
Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lu Y,Wan J,Yang Z,Lei X,Niu Q,Jiang L,Passtoors WM,Zang A,Fraering PC,Wu F
Sat Apr 01 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Protective effects of morin on lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting TLR4/NF-κB and activating Nrf2/HO-1 signaling pathways.
International immunopharmacology
Tian Y,Li Z,Shen B,Zhang Q,Feng H
Sat Apr 01 00:00:00 EDT 2017
Protective effects of morin on lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting TLR4/NF-κB and activating Nrf2/HO-1 signaling pathways.
International immunopharmacology
Tian Y,Li Z,Shen B,Zhang Q,Feng H
Sat Apr 01 00:00:00 EDT 2017
The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling.
Journal of molecular medicine (Berlin, Germany)
Lai D,Gao J,Bi X,He H,Shi X,Weng S,Chen Y,Yang Y,Ye Y,Fu G
Wed Feb 01 00:00:00 EST 2017
The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling.
Journal of molecular medicine (Berlin, Germany)
Lai D,Gao J,Bi X,He H,Shi X,Weng S,Chen Y,Yang Y,Ye Y,Fu G
Wed Feb 01 00:00:00 EST 2017
Proinflammatory effects of S100A8/A9 via TLR4 and RAGE signaling pathways in BV-2 microglial cells.
International journal of molecular medicine
Ma L,Sun P,Zhang JC,Zhang Q,Yao SL
Sat Jul 01 00:00:00 EDT 2017
Proinflammatory effects of S100A8/A9 via TLR4 and RAGE signaling pathways in BV-2 microglial cells.
International journal of molecular medicine
Ma L,Sun P,Zhang JC,Zhang Q,Yao SL
Sat Jul 01 00:00:00 EDT 2017
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Neuropharmacology
Song Z,Yang W,Zhou X,Yang L,Zhao D
Fri Sep 01 00:00:00 EDT 2017
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Neuropharmacology
Song Z,Yang W,Zhou X,Yang L,Zhao D
Fri Sep 01 00:00:00 EDT 2017
Activation of PPARγ inhibits HDAC1-mediated pulmonary arterial smooth muscle cell proliferation and its potential mechanisms.
European journal of pharmacology
Li F,Zhu Y,Wan Y,Xie X,Ke R,Zhai C,Pan Y,Yan X,Wang J,Shi W,Li M
Sun Nov 05 00:00:00 EDT 2017
Activation of PPARγ inhibits HDAC1-mediated pulmonary arterial smooth muscle cell proliferation and its potential mechanisms.
European journal of pharmacology
Li F,Zhu Y,Wan Y,Xie X,Ke R,Zhai C,Pan Y,Yan X,Wang J,Shi W,Li M
Sun Nov 05 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 EDT 2017
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Toxicology
Fu J,Xia X,Liu Z,Wang Y,Wang Y,Shi Q,Song X,Song E,Song Y
Sat Apr 15 00:00:00 EDT 2017
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Toxicology
Fu J,Xia X,Liu Z,Wang Y,Wang Y,Shi Q,Song X,Song E,Song Y
Sat Apr 15 00:00:00 EDT 2017
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Virchows Archiv : an international journal of pathology
Zhang X,Fu L,Xue D,Zhang X,Hao F,Xie L,He J,Gai J,Liu Y,Xu H,Li Q,Wang E
Mon May 01 00:00:00 EDT 2017
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Virchows Archiv : an international journal of pathology
Zhang X,Fu L,Xue D,Zhang X,Hao F,Xie L,He J,Gai J,Liu Y,Xu H,Li Q,Wang E
Mon May 01 00:00:00 EDT 2017
Central administration of tert-butylhydroquinone attenuates hypertension via regulating Nrf2 signaling in the hypothalamic paraventricular nucleus of hypertensive rats.
Toxicology and applied pharmacology
Bai J,Yu XJ,Liu KL,Wang FF,Jing GX,Li HB,Zhang Y,Huo CJ,Li X,Gao HL,Qi J,Kang YM
Sun Oct 15 00:00:00 EDT 2017
Central administration of tert-butylhydroquinone attenuates hypertension via regulating Nrf2 signaling in the hypothalamic paraventricular nucleus of hypertensive rats.
Toxicology and applied pharmacology
Bai J,Yu XJ,Liu KL,Wang FF,Jing GX,Li HB,Zhang Y,Huo CJ,Li X,Gao HL,Qi J,Kang YM
Sun Oct 15 00:00:00 EDT 2017
CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
OncoTargets and therapy
Qin C,Ren L,Ji M,Lv S,Wei Y,Zhu D,Lin Q,Xu P,Chang W,Xu J
Wed Nov 09 00:00:00 EST 2022
CDKL1 promotes tumor proliferation and invasion in colorectal cancer.
OncoTargets and therapy
Qin C,Ren L,Ji M,Lv S,Wei Y,Zhu D,Lin Q,Xu P,Chang W,Xu J
Wed Nov 09 00:00:00 EST 2022
Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma by suppressing the PI3K/AKT and NF-κB/COX-2 signaling pathways.
OncoTargets and therapy
Zhao J,Zhu J,Lv X,Xing J,Liu S,Chen C,Xu Y
Fri Dec 09 00:00:00 EST 2022
Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma by suppressing the PI3K/AKT and NF-κB/COX-2 signaling pathways.
OncoTargets and therapy
Zhao J,Zhu J,Lv X,Xing J,Liu S,Chen C,Xu Y
Fri Dec 09 00:00:00 EST 2022
MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Cell and tissue research
Xie X,Li S,Zhu Y,Liu L,Pan Y,Wang J,Shi W,Song Y,Yang L,Gao L,Zang W,Li M
Fri Sep 01 00:00:00 EDT 2017
MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Cell and tissue research
Xie X,Li S,Zhu Y,Liu L,Pan Y,Wang J,Shi W,Song Y,Yang L,Gao L,Zang W,Li M
Fri Sep 01 00:00:00 EDT 2017
Cooperative regulation of Gja1 expression by members of the AP-1 family cJun and cFos in TM3 Leydig and TM4 Sertoli cells.
Gene
Ghouili F,Martin LJ
Thu Nov 30 00:00:00 EST 2017
Cooperative regulation of Gja1 expression by members of the AP-1 family cJun and cFos in TM3 Leydig and TM4 Sertoli cells.
Gene
Ghouili F,Martin LJ
Thu Nov 30 00:00:00 EST 2017
Santamarine Inhibits NF-κB Activation and Induces Mitochondrial Apoptosis in A549 Lung Adenocarcinoma Cells via Oxidative Stress.
BioMed research international
Wu X,Zhu H,Yan J,Khan M,Yu X
Mon Jul 09 00:00:00 EDT 2018
Santamarine Inhibits NF-κB Activation and Induces Mitochondrial Apoptosis in A549 Lung Adenocarcinoma Cells via Oxidative Stress.
BioMed research international
Wu X,Zhu H,Yan J,Khan M,Yu X
Mon Jul 09 00:00:00 EDT 2018
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
Scientific reports
Fang W,Bi D,Zheng R,Cai N,Xu H,Zhou R,Lu J,Wan M,Xu X
Wed May 10 00:00:00 EDT 2017
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
Scientific reports
Fang W,Bi D,Zheng R,Cai N,Xu H,Zhou R,Lu J,Wan M,Xu X
Wed May 10 00:00:00 EDT 2017
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Redox biology
Chen X,Zhao X,Cai H,Sun H,Hu Y,Huang X,Kong W,Kong W
Tue Aug 01 00:00:00 EDT 2017
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Redox biology
Chen X,Zhao X,Cai H,Sun H,Hu Y,Huang X,Kong W,Kong W
Tue Aug 01 00:00:00 EDT 2017
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Inflammation
Tu J,Li W,Zhang Y,Wu X,Song Y,Kang L,Liu W,Wang K,Li S,Hua W,Yang C
Thu Jun 01 00:00:00 EDT 2017
Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma.
Oncotarget
Huang W,Zhou W,Li C,Yang Y,Shang YK,Chen C,Zhang J,Yao R,Wang P,Wen W,Liu HQ,Wang L,Li X,Bian H,Chen ZN
Tue Apr 18 00:00:00 EDT 2017
Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma.
Oncotarget
Huang W,Zhou W,Li C,Yang Y,Shang YK,Chen C,Zhang J,Yao R,Wang P,Wen W,Liu HQ,Wang L,Li X,Bian H,Chen ZN
Tue Apr 18 00:00:00 EDT 2017
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2.
Scientific reports
Xu S,Liu J,Shi J,Wang Z,Ji L
Tue Nov 28 00:00:00 EST 2017
2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2.
Scientific reports
Xu S,Liu J,Shi J,Wang Z,Ji L
Tue Nov 28 00:00:00 EST 2017
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Oncotarget
Wei X,Ye J,Shang Y,Chen H,Liu S,Liu L,Wang R
Tue Dec 12 00:00:00 EST 2017
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Oncotarget
Wei X,Ye J,Shang Y,Chen H,Liu S,Liu L,Wang R
Tue Dec 12 00:00:00 EST 2017
Correction: Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
The Journal of cell biology
Qu J,Sun W,Zhong J,Lv H,Zhu M,Xu J,Jin N,Xie Z,Tan M,Lin SH,Geng M,Ding J,Huang M
Mon Jul 24 00:00:00 EDT 2017
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway.
Oncotarget
Yan S,Wei X,Xu S,Sun H,Wang W,Liu L,Jiang X,Zhang Y,Che Y
Fri Oct 06 00:00:00 EDT 2017
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway.
Oncotarget
Yan S,Wei X,Xu S,Sun H,Wang W,Liu L,Jiang X,Zhang Y,Che Y
Fri Oct 06 00:00:00 EDT 2017
Necrostatin-1 attenuates early brain injury after subarachnoid hemorrhage in rats by inhibiting necroptosis.
Neuropsychiatric disease and treatment
Chen F,Su X,Lin Z,Lin Y,Yu L,Cai J,Kang D,Hu L
Wed Mar 30 00:00:00 EDT 2022
Necrostatin-1 attenuates early brain injury after subarachnoid hemorrhage in rats by inhibiting necroptosis.
Neuropsychiatric disease and treatment
Chen F,Su X,Lin Z,Lin Y,Yu L,Cai J,Kang D,Hu L
Wed Mar 30 00:00:00 EDT 2022
Inhibition of phosphodiesterase-5 suppresses calcineurin/NFAT- mediated TRPC6 expression in pulmonary artery smooth muscle cells.
Scientific reports
Li S,Pan Y,Ke R,Xie X,Zhai C,Shi W,Wang J,Yan X,Chai L,Wang Q,Zhang Q,Su X,Yang L,Gao L,Li M
Thu Jul 20 00:00:00 EDT 2017
Inhibition of phosphodiesterase-5 suppresses calcineurin/NFAT- mediated TRPC6 expression in pulmonary artery smooth muscle cells.
Scientific reports
Li S,Pan Y,Ke R,Xie X,Zhai C,Shi W,Wang J,Yan X,Chai L,Wang Q,Zhang Q,Su X,Yang L,Gao L,Li M
Thu Jul 20 00:00:00 EDT 2017
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
International journal of molecular sciences
Yang W,Sun Z,Yang B,Wang Q
Mon Jul 31 00:00:00 EDT 2017
Nrf2-Knockout Protects from Intestinal Injuries in C57BL/6J Mice Following Abdominal Irradiation with γ Rays.
International journal of molecular sciences
Yang W,Sun Z,Yang B,Wang Q
Mon Jul 31 00:00:00 EDT 2017
Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis.
Cell research
Lu Y,Xie S,Zhang W,Zhang C,Gao C,Sun Q,Cai Y,Xu Z,Xiao M,Xu Y,Huang X,Wu X,Liu W,Wang F,Kang Y,Zhou T
Fri Dec 01 00:00:00 EST 2017
Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells.
Scientific reports
Xie Q,Fan F,Wei W,Liu Y,Xu Z,Zhai L,Qi Y,Ye B,Zhang Y,Basu S,Zhao Z,Wu J,Xu P
Mon Jan 23 00:00:00 EST 2017
Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells.
Scientific reports
Xie Q,Fan F,Wei W,Liu Y,Xu Z,Zhai L,Qi Y,Ye B,Zhang Y,Basu S,Zhao Z,Wu J,Xu P
Mon Jan 23 00:00:00 EST 2017
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Oncotarget
Hu YH,Chen Q,Lu YX,Zhang JM,Lin C,Zhang F,Zhang WJ,Li XM,Zhang W,Li XN
Tue Jul 11 00:00:00 EDT 2017
Repression of YAP by NCTD disrupts NSCLC progression.
Oncotarget
Guo J,Wu Y,Yang L,Du J,Gong K,Chen W,Dai J,Li X,Xi S
Tue Jan 10 00:00:00 EST 2017
Repression of YAP by NCTD disrupts NSCLC progression.
Oncotarget
Guo J,Wu Y,Yang L,Du J,Gong K,Chen W,Dai J,Li X,Xi S
Tue Jan 10 00:00:00 EST 2017
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
International journal of obesity (2005)
Gao Y,Li J,Xu X,Wang S,Yang Y,Zhou J,Zhang L,Zheng F,Li X,Wang B
Mon May 01 00:00:00 EDT 2017
The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins.
Oncotarget
You L,Liu H,Huang J,Xie W,Wei J,Ye X,Qian W
Tue Jan 31 00:00:00 EST 2017
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Nature immunology
Li S,Zhu M,Pan R,Fang T,Cao YY,Chen S,Zhao X,Lei CQ,Guo L,Chen Y,Li CM,Jokitalo E,Yin Y,Shu HB,Guo D
Tue Mar 01 00:00:00 EST 2016
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Nature immunology
Li S,Zhu M,Pan R,Fang T,Cao YY,Chen S,Zhao X,Lei CQ,Guo L,Chen Y,Li CM,Jokitalo E,Yin Y,Shu HB,Guo D
Tue Mar 01 00:00:00 EST 2016
Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons.
Acta neuropathologica
Jiang P,Gan M,Yen SH,Moussaud S,McLean PJ,Dickson DW
Fri Jul 01 00:00:00 EDT 2016
Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons.
Acta neuropathologica
Jiang P,Gan M,Yen SH,Moussaud S,McLean PJ,Dickson DW
Fri Jul 01 00:00:00 EDT 2016
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Genome research
Gesson K,Rescheneder P,Skoruppa MP,von Haeseler A,Dechat T,Foisner R
Fri Apr 01 00:00:00 EDT 2016
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Genome research
Gesson K,Rescheneder P,Skoruppa MP,von Haeseler A,Dechat T,Foisner R
Fri Apr 01 00:00:00 EDT 2016
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Genome research
Gesson K,Rescheneder P,Skoruppa MP,von Haeseler A,Dechat T,Foisner R
Fri Apr 01 00:00:00 EDT 2016
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Genome research
Gesson K,Rescheneder P,Skoruppa MP,von Haeseler A,Dechat T,Foisner R
Fri Apr 01 00:00:00 EDT 2016
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Genome research
Gesson K,Rescheneder P,Skoruppa MP,von Haeseler A,Dechat T,Foisner R
Fri Apr 01 00:00:00 EDT 2016
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Genome research
Gesson K,Rescheneder P,Skoruppa MP,von Haeseler A,Dechat T,Foisner R
Fri Apr 01 00:00:00 EDT 2016
Regulation of a TGF-β1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells.
Oncogene
Wu J,Lu M,Li Y,Shang YK,Wang SJ,Meng Y,Wang Z,Li ZS,Chen H,Chen ZN,Bian H
Thu Oct 20 00:00:00 EDT 2016
Regulation of a TGF-β1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells.
Oncogene
Wu J,Lu M,Li Y,Shang YK,Wang SJ,Meng Y,Wang Z,Li ZS,Chen H,Chen ZN,Bian H
Thu Oct 20 00:00:00 EDT 2016
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.
Free radical biology & medicine
Lee DH,Han DH,Nam KT,Park JS,Kim SH,Lee M,Kim G,Min BS,Cha BS,Lee YS,Sung SH,Jeong H,Ji HW,Lee MJ,Lee JS,Lee HY,Chun Y,Kim J,Komatsu M,Lee YH,Bae SH
Sat Oct 01 00:00:00 EDT 2016
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.
Free radical biology & medicine
Lee DH,Han DH,Nam KT,Park JS,Kim SH,Lee M,Kim G,Min BS,Cha BS,Lee YS,Sung SH,Jeong H,Ji HW,Lee MJ,Lee JS,Lee HY,Chun Y,Kim J,Komatsu M,Lee YH,Bae SH
Sat Oct 01 00:00:00 EDT 2016
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Clinical nutrition (Edinburgh, Scotland)
Shi H,Shi A,Dong L,Lu X,Wang Y,Zhao J,Dai F,Guo X
Thu Dec 01 00:00:00 EST 2016
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Clinical nutrition (Edinburgh, Scotland)
Shi H,Shi A,Dong L,Lu X,Wang Y,Zhao J,Dai F,Guo X
Thu Dec 01 00:00:00 EST 2016
miR-34a-5p Inhibition Alleviates Intestinal Ischemia/Reperfusion-Induced Reactive Oxygen Species Accumulation and Apoptosis via Activation of SIRT1 Signaling.
Antioxidants & redox signaling
Wang G,Yao J,Li Z,Zu G,Feng D,Shan W,Li Y,Hu Y,Zhao Y,Tian X
Fri Jun 10 00:00:00 EDT 2016
miR-34a-5p Inhibition Alleviates Intestinal Ischemia/Reperfusion-Induced Reactive Oxygen Species Accumulation and Apoptosis via Activation of SIRT1 Signaling.
Antioxidants & redox signaling
Wang G,Yao J,Li Z,Zu G,Feng D,Shan W,Li Y,Hu Y,Zhao Y,Tian X
Fri Jun 10 00:00:00 EDT 2016
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
PLoS pathogens
Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H
Fri Jul 01 00:00:00 EDT 2016
Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.
PLoS pathogens
Ren Y,Zhao P,Liu J,Yuan Y,Cheng Q,Zuo Y,Qian L,Liu C,Guo T,Zhang L,Wang X,Qian G,Li L,Ge J,Dai J,Xiong S,Zheng H
Fri Jul 01 00:00:00 EDT 2016
The E3 Ubiquitin Ligase c-Cbl Inhibits Microglia-Mediated CNS Inflammation by Regulating PI3K/Akt/NF-κB Pathway.
CNS neuroscience & therapeutics
Dong L,Li YZ,An HT,Wang YL,Chen SH,Qian YJ,Wang K,Zhen JL,Fan Z,Gong XL,Zheng Y,Wang XM
Mon Aug 01 00:00:00 EDT 2016
The E3 Ubiquitin Ligase c-Cbl Inhibits Microglia-Mediated CNS Inflammation by Regulating PI3K/Akt/NF-κB Pathway.
CNS neuroscience & therapeutics
Dong L,Li YZ,An HT,Wang YL,Chen SH,Qian YJ,Wang K,Zhen JL,Fan Z,Gong XL,Zheng Y,Wang XM
Mon Aug 01 00:00:00 EDT 2016
P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Tome ME,Herndon JM,Schaefer CP,Jacobs LM,Zhang Y,Jarvis CK,Davis TP
Tue Nov 01 00:00:00 EDT 2016
P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Tome ME,Herndon JM,Schaefer CP,Jacobs LM,Zhang Y,Jarvis CK,Davis TP
Tue Nov 01 00:00:00 EDT 2016
Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner.
Journal of lipid research
Shao W,Machamer CE,Espenshade PJ
Mon Aug 01 00:00:00 EDT 2016
Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner.
Journal of lipid research
Shao W,Machamer CE,Espenshade PJ
Mon Aug 01 00:00:00 EDT 2016
Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein.
Journal of virology
Zhang J,Huang F,Tan L,Bai C,Chen B,Liu J,Liang J,Liu C,Zhang S,Lu G,Chen Y,Zhang H
Fri Apr 01 00:00:00 EDT 2016
Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein.
Journal of virology
Zhang J,Huang F,Tan L,Bai C,Chen B,Liu J,Liang J,Liu C,Zhang S,Lu G,Chen Y,Zhang H
Fri Apr 01 00:00:00 EDT 2016
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
Journal of virology
Zhang LK,Xin QL,Zhu SL,Wan WW,Wang W,Xiao G
Tue Nov 15 00:00:00 EST 2016
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
Journal of virology
Zhang LK,Xin QL,Zhu SL,Wan WW,Wang W,Xiao G
Tue Nov 15 00:00:00 EST 2016
Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells.
International journal of oncology
He W,Ye X,Huang X,Lel W,You L,Wang L,Chen X,Qian W
Fri Apr 01 00:00:00 EDT 2016
Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells.
International journal of oncology
He W,Ye X,Huang X,Lel W,You L,Wang L,Chen X,Qian W
Fri Apr 01 00:00:00 EDT 2016
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Environmental toxicology and pharmacology
Fu J,Shi Q,Song X,Xia X,Su C,Liu Z,Song E,Song Y
Fri Jan 01 00:00:00 EST 2016
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Environmental toxicology and pharmacology
Fu J,Shi Q,Song X,Xia X,Su C,Liu Z,Song E,Song Y
Fri Jan 01 00:00:00 EST 2016
MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes.
Journal of immunology (Baltimore, Md. : 1950)
Chen LT,Hu MM,Xu ZS,Liu Y,Shu HB
Fri Jul 01 00:00:00 EDT 2016
MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes.
Journal of immunology (Baltimore, Md. : 1950)
Chen LT,Hu MM,Xu ZS,Liu Y,Shu HB
Fri Jul 01 00:00:00 EDT 2016
Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells.
European journal of pharmacology
Yu Y,Huang Z,Mao Z,Zhang Y,Jin M,Chen W,Zhang W,Yu B,Zhang W,Alaster Lau HY
Sun Jun 05 00:00:00 EDT 2016
Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells.
European journal of pharmacology
Yu Y,Huang Z,Mao Z,Zhang Y,Jin M,Chen W,Zhang W,Yu B,Zhang W,Alaster Lau HY
Sun Jun 05 00:00:00 EDT 2016
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Toxicology
Su C,Shi Q,Song X,Fu J,Liu Z,Wang Y,Wang Y,Xia X,Song E,Song Y
Fri Jul 01 00:00:00 EDT 2016
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Toxicology
Su C,Shi Q,Song X,Fu J,Liu Z,Wang Y,Wang Y,Xia X,Song E,Song Y
Fri Jul 01 00:00:00 EDT 2016
Unpredicted Downregulation of RAD51 Suggests Genome Instability Induced by Tetrachlorobenzoquinone.
Chemical research in toxicology
Song X,Shi Q,Liu Z,Wang Y,Wang Y,Song E,Song Y
Mon Dec 19 00:00:00 EST 2016
Unpredicted Downregulation of RAD51 Suggests Genome Instability Induced by Tetrachlorobenzoquinone.
Chemical research in toxicology
Song X,Shi Q,Liu Z,Wang Y,Wang Y,Song E,Song Y
Mon Dec 19 00:00:00 EST 2016
The absence of p53 during Human Cytomegalovirus infection leads to decreased UL53 expression, disrupting UL50 localization to the inner nuclear membrane, and thereby inhibiting capsid nuclear egress.
Virology
Kuan MI,O'Dowd JM,Fortunato EA
Sat Oct 01 00:00:00 EDT 2016
The absence of p53 during Human Cytomegalovirus infection leads to decreased UL53 expression, disrupting UL50 localization to the inner nuclear membrane, and thereby inhibiting capsid nuclear egress.
Virology
Kuan MI,O'Dowd JM,Fortunato EA
Sat Oct 01 00:00:00 EDT 2016
Identification and characterization of an endoplasmic reticulum localization motif.
Biochemical and biophysical research communications
Nie YW,Wang M,Zhang P,Huan L,Liu DJ
Fri Apr 22 00:00:00 EDT 2016
Identification and characterization of an endoplasmic reticulum localization motif.
Biochemical and biophysical research communications
Nie YW,Wang M,Zhang P,Huan L,Liu DJ
Fri Apr 22 00:00:00 EDT 2016
PRELP (proline/arginine-rich end leucine-rich repeat protein) promotes osteoblastic differentiation of preosteoblastic MC3T3-E1 cells by regulating the β-catenin pathway.
Biochemical and biophysical research communications
Li H,Cui Y,Luan J,Zhang X,Li C,Zhou X,Shi L,Wang H,Han J
Fri Feb 12 00:00:00 EST 2016
PRELP (proline/arginine-rich end leucine-rich repeat protein) promotes osteoblastic differentiation of preosteoblastic MC3T3-E1 cells by regulating the β-catenin pathway.
Biochemical and biophysical research communications
Li H,Cui Y,Luan J,Zhang X,Li C,Zhou X,Shi L,Wang H,Han J
Fri Feb 12 00:00:00 EST 2016
A new steroidal saponin, furotrilliumoside from Trillium tschonoskii inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways.
Fitoterapia
Yan T,Yu X,Sun X,Meng D,Jia JM
Thu Dec 01 00:00:00 EST 2016
A new steroidal saponin, furotrilliumoside from Trillium tschonoskii inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways.
Fitoterapia
Yan T,Yu X,Sun X,Meng D,Jia JM
Thu Dec 01 00:00:00 EST 2016
Toll-like receptor 2-mediated MAPKs and NF-κB activation requires the GNAO1-dependent pathway in human mast cells.
Integrative biology : quantitative biosciences from nano to macro
Jin M,Yu B,Zhang W,Zhang W,Xiao Z,Mao Z,Lai Y,Lin D,Ma Q,Pan E,Zhang Y,Yu Y
Mon Sep 12 00:00:00 EDT 2016
Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway.
PloS one
Huang X,He Z,Jiang X,Hou M,Tang Z,Zhen X,Liang Y,Ma J
Mon Aug 08 00:00:00 EDT 2016
Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway.
PloS one
Huang X,He Z,Jiang X,Hou M,Tang Z,Zhen X,Liang Y,Ma J
Mon Aug 08 00:00:00 EDT 2016
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Oncotarget
Song Z,Zhu T,Zhou X,Barrow P,Yang W,Cui Y,Yang L,Zhao D
Tue Mar 15 00:00:00 EDT 2016
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Oncotarget
Song Z,Zhu T,Zhou X,Barrow P,Yang W,Cui Y,Yang L,Zhao D
Tue Mar 15 00:00:00 EDT 2016
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.
Aging cell
Han X,Tai H,Wang X,Wang Z,Zhou J,Wei X,Ding Y,Gong H,Mo C,Zhang J,Qin J,Ma Y,Huang N,Xiang R,Xiao H
Wed Jun 01 00:00:00 EDT 2016
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Nutrients
Tao X,Sun X,Xu L,Yin L,Han X,Qi Y,Xu Y,Zhao Y,Wang C,Peng J
Fri Jul 08 00:00:00 EDT 2016
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Nutrients
Tao X,Sun X,Xu L,Yin L,Han X,Qi Y,Xu Y,Zhao Y,Wang C,Peng J
Fri Jul 08 00:00:00 EDT 2016
Salusin-β contributes to vascular inflammation associated with pulmonary arterial hypertension in rats.
The Journal of thoracic and cardiovascular surgery
Xu T,Zhang Z,Liu T,Zhang W,Liu J,Wang W,Wang J
Sat Oct 01 00:00:00 EDT 2016
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Free radical research
Nie H,Xue X,Liu G,Guan G,Liu H,Sun L,Zhao L,Wang X,Chen Z
Thu Feb 09 00:00:00 EST 2017
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Free radical research
Nie H,Xue X,Liu G,Guan G,Liu H,Sun L,Zhao L,Wang X,Chen Z
Thu Feb 09 00:00:00 EST 2017
Fibroblast growth factor rescues brain endothelial cells lacking presenilin 1 from apoptotic cell death following serum starvation.
Scientific reports
Gama Sosa MA,De Gasperi R,Hof PR,Elder GA
Fri Jul 22 00:00:00 EDT 2016
From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft.
Toxicological sciences : an official journal of the Society of Toxicology
Fu J,Shi Q,Song X,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Oct 01 00:00:00 EDT 2016
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
International journal of oncology
He K,Tong D,Zhang S,Cai D,Wang L,Yang Y,Gao L,Chang S,Guo B,Song T,Li A,Huang C
Thu Oct 01 00:00:00 EDT 2015
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
International journal of oncology
He K,Tong D,Zhang S,Cai D,Wang L,Yang Y,Gao L,Chang S,Guo B,Song T,Li A,Huang C
Thu Oct 01 00:00:00 EDT 2015
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
International immunopharmacology
Shi Q,Song X,Fu J,Su C,Xia X,Song E,Song Y
Tue Dec 01 00:00:00 EST 2015
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
International immunopharmacology
Shi Q,Song X,Fu J,Su C,Xia X,Song E,Song Y
Tue Dec 01 00:00:00 EST 2015
Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.
Journal of immunology (Baltimore, Md. : 1950)
Zhu M,Fang T,Li S,Meng K,Guo D
Wed Jul 01 00:00:00 EDT 2015
Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.
Journal of immunology (Baltimore, Md. : 1950)
Zhu M,Fang T,Li S,Meng K,Guo D
Wed Jul 01 00:00:00 EDT 2015
The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells.
Medical oncology (Northwood, London, England)
Gao N,He H,Xiao L,Gao X,Shi H,Wu Q,Xu N,Lei Y,Song X,Hou Y
Wed Apr 01 00:00:00 EDT 2015
The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells.
Medical oncology (Northwood, London, England)
Gao N,He H,Xiao L,Gao X,Shi H,Wu Q,Xu N,Lei Y,Song X,Hou Y
Wed Apr 01 00:00:00 EDT 2015
Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3.
Brain research
Hu Y,Duan M,Liang S,Wang Y,Feng Y
Fri Apr 24 00:00:00 EDT 2015
Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3.
Brain research
Hu Y,Duan M,Liang S,Wang Y,Feng Y
Fri Apr 24 00:00:00 EDT 2015
Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches.
Evidence-based complementary and alternative medicine : eCAM
Shiau JY,Yin SY,Chang SL,Hsu YJ,Chen KW,Kuo TF,Feng CS,Yang NS,Shyur LF,Yang WC,Wen TN
Wed Nov 11 00:00:00 EST 2015
Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches.
Evidence-based complementary and alternative medicine : eCAM
Shiau JY,Yin SY,Chang SL,Hsu YJ,Chen KW,Kuo TF,Feng CS,Yang NS,Shyur LF,Yang WC,Wen TN
Wed Nov 11 00:00:00 EST 2015
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Parasitology research
Mao Q,Xie Z,Wang X,Chen W,Ren M,Shang M,Lei H,Tian Y,Li S,Liang P,Chen T,Liang C,Xu J,Li X,Huang Y,Yu X
Sun Feb 01 00:00:00 EST 2015
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Parasitology research
Mao Q,Xie Z,Wang X,Chen W,Ren M,Shang M,Lei H,Tian Y,Li S,Liang P,Chen T,Liang C,Xu J,Li X,Huang Y,Yu X
Sun Feb 01 00:00:00 EST 2015
The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo.
PloS one
Jin X,Liu Y,Liu J,Lu W,Liang Z,Zhang D,Liu G,Zhu H,Xu N,Liang S
Sun May 08 00:00:00 EDT 2016
The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo.
PloS one
Jin X,Liu Y,Liu J,Lu W,Liang Z,Zhang D,Liu G,Zhu H,Xu N,Liang S
Sun May 08 00:00:00 EDT 2016
Demethylzeylasteral (T-96) Treatment Ameliorates Mice Lupus Nephritis Accompanied by Inhibiting Activation of NF-κB Pathway.
PloS one
Hu Q,Yang C,Wang Q,Zeng H,Qin W
Fri May 06 00:00:00 EDT 2016
Demethylzeylasteral (T-96) Treatment Ameliorates Mice Lupus Nephritis Accompanied by Inhibiting Activation of NF-κB Pathway.
PloS one
Hu Q,Yang C,Wang Q,Zeng H,Qin W
Fri May 06 00:00:00 EDT 2016
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Molecular cancer
Wang F,Yang JL,Yu KK,Xu M,Xu YZ,Chen L,Lu YM,Fang HS,Wang XY,Hu ZQ,Li FF,Kan L,Luo J,Wang SY
Tue Jan 27 00:00:00 EST 2015
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Molecular cancer
Wang F,Yang JL,Yu KK,Xu M,Xu YZ,Chen L,Lu YM,Fang HS,Wang XY,Hu ZQ,Li FF,Kan L,Luo J,Wang SY
Tue Jan 27 00:00:00 EST 2015
WNT5A promotes stemness characteristics in nasopharyngeal carcinoma cells leading to metastasis and tumorigenesis.
Oncotarget
Qin L,Yin YT,Zheng FJ,Peng LX,Yang CF,Bao YN,Liang YY,Li XJ,Xiang YQ,Sun R,Li AH,Zou RH,Pei XQ,Huang BJ,Kang TB,Liao DF,Zeng YX,Williams BO,Qian CN
Thu Apr 30 00:00:00 EDT 2015
AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver.
PloS one
Liu S,Jing F,Yu C,Gao L,Qin Y,Zhao J
Tue Jan 26 00:00:00 EST 2016
AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver.
PloS one
Liu S,Jing F,Yu C,Gao L,Qin Y,Zhao J
Tue Jan 26 00:00:00 EST 2016
SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colorectal cancer by activation of the Wnt/β-catenin signaling pathway.
Cancer letters
Hu TH,Yao Y,Yu S,Han LL,Wang WJ,Guo H,Tian T,Ruan ZP,Kang XM,Wang J,Wang SH,Nan KJ
Fri Nov 28 00:00:00 EST 2014
SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colorectal cancer by activation of the Wnt/β-catenin signaling pathway.
Cancer letters
Hu TH,Yao Y,Yu S,Han LL,Wang WJ,Guo H,Tian T,Ruan ZP,Kang XM,Wang J,Wang SH,Nan KJ
Fri Nov 28 00:00:00 EST 2014
Oridonin induces NPM mutant protein translocation and apoptosis in NPM1c+ acute myeloid leukemia cells in vitro.
Acta pharmacologica Sinica
Li FF,Yi S,Wen L,He J,Yang LJ,Zhao J,Zhang BP,Cui GH,Chen Y
Sun Jun 01 00:00:00 EDT 2014
Oridonin induces NPM mutant protein translocation and apoptosis in NPM1c+ acute myeloid leukemia cells in vitro.
Acta pharmacologica Sinica
Li FF,Yi S,Wen L,He J,Yang LJ,Zhao J,Zhang BP,Cui GH,Chen Y
Sun Jun 01 00:00:00 EDT 2014
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
International immunopharmacology
Xia X,Su C,Fu J,Zhang P,Jiang X,Xu D,Hu L,Song E,Song Y
Wed Oct 01 00:00:00 EDT 2014
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
International immunopharmacology
Xia X,Su C,Fu J,Zhang P,Jiang X,Xu D,Hu L,Song E,Song Y
Wed Oct 01 00:00:00 EDT 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 EDT 2014
Pao Pereira Extract Suppresses Castration-Resistant Prostate Cancer Cell Growth, Survival, and Invasion Through Inhibition of NFκB Signaling.
Integrative cancer therapies
Chang C,Zhao W,Xie B,Deng Y,Han T,Cui Y,Dai Y,Zhang Z,Gao J,Guo H,Yan J
Thu May 01 00:00:00 EDT 2014
Pao Pereira Extract Suppresses Castration-Resistant Prostate Cancer Cell Growth, Survival, and Invasion Through Inhibition of NFκB Signaling.
Integrative cancer therapies
Chang C,Zhao W,Xie B,Deng Y,Han T,Cui Y,Dai Y,Zhang Z,Gao J,Guo H,Yan J
Thu May 01 00:00:00 EDT 2014
Krüppel-like factor 6 is a co-activator of NF-κB that mediates p65-dependent transcription of selected downstream genes.
The Journal of biological chemistry
Zhang Y,Lei CQ,Hu YH,Xia T,Li M,Zhong B,Shu HB
Fri May 02 00:00:00 EDT 2014
Krüppel-like factor 6 is a co-activator of NF-κB that mediates p65-dependent transcription of selected downstream genes.
The Journal of biological chemistry
Zhang Y,Lei CQ,Hu YH,Xia T,Li M,Zhong B,Shu HB
Fri May 02 00:00:00 EDT 2014
CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα.
Journal of molecular cell biology
Li D,Zhu H,Liang C,Li W,Xing G,Ma L,Ding L,Zhang Y,He F,Zhang L
Wed Oct 01 00:00:00 EDT 2014
Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse model.
Antioxidants & redox signaling
Shan Y,Schoenfeld RA,Hayashi G,Napoli E,Akiyama T,Iodi Carstens M,Carstens EE,Pook MA,Cortopassi GA
Fri Nov 01 00:00:00 EDT 2013
Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse model.
Antioxidants & redox signaling
Shan Y,Schoenfeld RA,Hayashi G,Napoli E,Akiyama T,Iodi Carstens M,Carstens EE,Pook MA,Cortopassi GA
Fri Nov 01 00:00:00 EDT 2013
Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway.
Toxicology
Shi H,Dong L,Jiang J,Zhao J,Zhao G,Dang X,Lu X,Jia M
Mon Jan 07 00:00:00 EST 2013
Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway.
Toxicology
Shi H,Dong L,Jiang J,Zhao J,Zhao G,Dang X,Lu X,Jia M
Mon Jan 07 00:00:00 EST 2013
Conditioned medium of Wnt/β-catenin signaling-activated olfactory ensheathing cells promotes synaptogenesis and neurite growth in vitro.
Cellular and molecular neurobiology
Yang Z,Wu Y,Zheng L,Zhang C,Yang J,Shi M,Feng D,Wu Z,Wang YZ
Tue Oct 01 00:00:00 EDT 2013
Conditioned medium of Wnt/β-catenin signaling-activated olfactory ensheathing cells promotes synaptogenesis and neurite growth in vitro.
Cellular and molecular neurobiology
Yang Z,Wu Y,Zheng L,Zhang C,Yang J,Shi M,Feng D,Wu Z,Wang YZ
Tue Oct 01 00:00:00 EDT 2013
Adeno-associated virus Rep78 restricts adenovirus E1B55K-mediated p53 nuclear exportation.
Acta biochimica et biophysica Sinica
Wang J,Li W,Wang R,Xue J,Chen J
Fri Feb 01 00:00:00 EST 2013
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Experimental and therapeutic medicine
Tu JB,Ma RZ,Dong Q,Jiang F,Hu XY,Li QY,Pattar P,Zhang H
Thu Aug 01 00:00:00 EDT 2013
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Experimental and therapeutic medicine
Tu JB,Ma RZ,Dong Q,Jiang F,Hu XY,Li QY,Pattar P,Zhang H
Thu Aug 01 00:00:00 EDT 2013
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
PloS one
Ning Q,Liu C,Hou L,Meng M,Zhang X,Luo M,Shao S,Zuo X,Zhao X
Thu Jan 16 00:00:00 EST 2014
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
PloS one
Ning Q,Liu C,Hou L,Meng M,Zhang X,Luo M,Shao S,Zuo X,Zhao X
Thu Jan 16 00:00:00 EST 2014
Epstein-Barr Virus_Encoded LMP1 upregulates microRNA-21 to promote the resistance of nasopharyngeal carcinoma cells to cisplatin-induced Apoptosis by suppressing PDCD4 and Fas-L.
PloS one
Yang GD,Huang TJ,Peng LX,Yang CF,Liu RY,Huang HB,Chu QQ,Yang HJ,Huang JL,Zhu ZY,Qian CN,Huang BJ
Tue Feb 24 00:00:00 EST 2015
Epstein-Barr Virus_Encoded LMP1 upregulates microRNA-21 to promote the resistance of nasopharyngeal carcinoma cells to cisplatin-induced Apoptosis by suppressing PDCD4 and Fas-L.
PloS one
Yang GD,Huang TJ,Peng LX,Yang CF,Liu RY,Huang HB,Chu QQ,Yang HJ,Huang JL,Zhu ZY,Qian CN,Huang BJ
Tue Feb 24 00:00:00 EST 2015
LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection.
Proceedings of the National Academy of Sciences of the United States of America
Li Y,Chen R,Zhou Q,Xu Z,Li C,Wang S,Mao A,Zhang X,He W,Shu HB
Tue Jul 17 00:00:00 EDT 2012
LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection.
Proceedings of the National Academy of Sciences of the United States of America
Li Y,Chen R,Zhou Q,Xu Z,Li C,Wang S,Mao A,Zhang X,He W,Shu HB
Tue Jul 17 00:00:00 EDT 2012
Hypoxia increases CX3CR1 expression via HIF-1 and NF‑κB in androgen-independent prostate cancer cells.
International journal of oncology
Xiao LJ,Chen YY,Lin P,Zou HF,Lin F,Zhao LN,Li D,Guo L,Tang JB,Zheng XL,Yu XG
Thu Nov 01 00:00:00 EDT 2012
Hypoxia increases CX3CR1 expression via HIF-1 and NF‑κB in androgen-independent prostate cancer cells.
International journal of oncology
Xiao LJ,Chen YY,Lin P,Zou HF,Lin F,Zhao LN,Li D,Guo L,Tang JB,Zheng XL,Yu XG
Thu Nov 01 00:00:00 EDT 2012
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Journal of biochemical and molecular toxicology
Tu JB,Dong Q,Hu XY,Jiang F,Ma RZ,He LY,Yang ZQ
Sat Sep 01 00:00:00 EDT 2012
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Journal of biochemical and molecular toxicology
Tu JB,Dong Q,Hu XY,Jiang F,Ma RZ,He LY,Yang ZQ
Sat Sep 01 00:00:00 EDT 2012
Activation of the Wnt/β-catenin signaling pathway is associated with glial proliferation in the adult spinal cord of ALS transgenic mice.
Biochemical and biophysical research communications
Chen Y,Guan Y,Liu H,Wu X,Yu L,Wang S,Zhao C,Du H,Wang X
Fri Apr 06 00:00:00 EDT 2012
Activation of the Wnt/β-catenin signaling pathway is associated with glial proliferation in the adult spinal cord of ALS transgenic mice.
Biochemical and biophysical research communications
Chen Y,Guan Y,Liu H,Wu X,Yu L,Wang S,Zhao C,Du H,Wang X
Fri Apr 06 00:00:00 EDT 2012
1,2,3,4,6-penta-O-galloyl-β-D-glucose protects PC12 Cells from MPP(+)-mediated cell death by inducing heme oxygenase-1 in an ERK- and Akt-dependent manner.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
Chen H,Li H,Cao F,Zhen L,Bai J,Yuan S,Mei Y
Mon Oct 01 00:00:00 EDT 2012
1,2,3,4,6-penta-O-galloyl-β-D-glucose protects PC12 Cells from MPP(+)-mediated cell death by inducing heme oxygenase-1 in an ERK- and Akt-dependent manner.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
Chen H,Li H,Cao F,Zhen L,Bai J,Yuan S,Mei Y
Mon Oct 01 00:00:00 EDT 2012
Eugenolol and glyceryl-isoeugenol suppress LPS-induced iNOS expression by down-regulating NF-kappaB AND AP-1 through inhibition of MAPKS and AKT/IkappaBalpha signaling pathways in macrophages.
International journal of immunopathology and pharmacology
Yeh JL,Hsu JH,Hong YS,Wu JR,Liang JC,Wu BN,Chen IJ,Liou SF
Thu Aug 18 00:00:00 EDT 2011
KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways.
British journal of pharmacology
Yeh JL,Hsu JH,Wu PJ,Liou SF,Liu CP,Chen IJ,Wu BN,Dai ZK,Wu JR
Mon Mar 01 00:00:00 EST 2010
KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways.
British journal of pharmacology
Yeh JL,Hsu JH,Wu PJ,Liou SF,Liu CP,Chen IJ,Wu BN,Dai ZK,Wu JR
Mon Mar 01 00:00:00 EST 2010
