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Invitrogen
MA1-06103 detects lamin B in human, mouse, rat, bovine, ovine, rabbit, zebrafish, and canine samples.
MA1-06103 has sucessfully been used in immunocytochemistry, immunohistochemistry, ELISA, and flow cytometry procedures.
The MA1-06103 immunogen is purified rat liver lamins.
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Defects in the LMNB1 gene can cause Leukodystrophy, demyelinating, autosomal dominant, adult-onset (ADLD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lamin-B1; MGC111419
Gene Aliases: ADLD; fc06g01; LMN; LMN2; LMNB; LMNB1; wu:fc06g01
UniProt ID: (Human) P20700, (Mouse) P14733, (Rat) P70615
Entrez Gene ID: (Rabbit) 100346094, (Human) 4001, (Sheep) 100037680, (Dog) 474663, (Bovine) 540643, (Mouse) 16906, (Rat) 116685, (Zebrafish) 195816
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