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Lass2 Antibody (PA5-115496) in ICC/IF
Immunocytochemistry analysis of Lass2 in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115496). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-115496
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CERS2(Accession Q96G23), corresponding to amino acid residues T346-D380.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900132
Product Specific Information
Antibody detects endogenous levels of total LASS2.
Target Information
LASS2 is a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ceramide synthase 2; CerS2; FLJ10243; LAG1 homolog, ceramide synthase 2; LAG1 longevity assurance 2; LAG1 longevity assurance homolog 2; longevity assurance (LAG1, S. cerevisiae) homolog 2; longevity assurance homolog 2; MGC987; SP260; Sphingosine N-acyltransferase CERS2; TRAM homolog 3; Translocating chain-associating membrane protein homolog 3; Tumor metastasis-suppressor gene 1 protein; Very-long-chain ceramide synthase CERS2
Gene Aliases: 0610013I17Rik; AI225939; CERS2; L3; LASS2; SP260; TMSG1; TRH3
UniProt ID: (Human) Q96G23, (Mouse) Q924Z4
Entrez Gene ID: (Human) 29956, (Mouse) 76893, (Rat) 310667
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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