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Product Details
PA5-62389
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Ly-108. Recombinant protein control fragment (Product #RP-101416).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2643612
Product Specific Information
Immunogen sequence: LPLEFPAGEK VNFITWLFNE TSLAFIVPHE TKSPEIHVTN PKQGKRLNFT QSYSLQLSNL KMEDTGSYRA QISTKT
Highest antigen sequence identity to the following orthologs: Mouse - 50%, Rat - 50%.
Target Information
Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating NK receptor; CD352; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTB-A; NTBA receptor; SLAM family member 6
Gene Aliases: CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000; SLAMF6; UNQ6123/PRO20080
UniProt ID: (Human) Q96DU3
Entrez Gene ID: (Human) 114836
natural killer cell differentiation
natural killer cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
innate immune response
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
T-helper 17 cell lineage commitment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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