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FIGURE: 1 / 1
Ly-108 Antibody (PA5-87823) in WB
Western blot analysis of Ly-108 in various lysates. Samples were incubated with Ly-108 Polyclonal antibody (Product # PA5-87823) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-87823
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 24-215 of human SLAMF6 (NP_0011716431)
Conjugate
Form
Liquid
Concentration
1.9 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804432
Product Specific Information
Positive Samples: Jurkat, Mouse lung, Mouse spleen, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein
Immunogen sequence: SLTPLMVNGI LGESVTLPLE FPAGEKVNFI TWLFNETSLA FIVPHETKSP EIHVTNPKQG KRLNFTQSYS LQLSNLKMED TGSYRAQIST KTSAKLSSYT LRILRQLRNI QVTNHSQLFQ NMTCELHLTC SVEDADDNVS FRWEALGNTL SSQPNLTVSW DPRISSEQDY TCIAENAVSN LSFSVSAQKL CE
Target Information
Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating NK receptor; CD352; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTB-A; NTBA receptor; SLAM family member 6
Gene Aliases: CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000; SLAMF6; UNQ6123/PRO20080
UniProt ID: (Human) Q96DU3
Entrez Gene ID: (Human) 114836
natural killer cell differentiation
natural killer cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
innate immune response
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
T-helper 17 cell lineage commitment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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