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Ly-108 Antibody (MA5-51526) in IHC (P)
Immunohistochemistry analysis of Ly-108 in paraffin-embedded human tonsil. Samples were incubated with Ly-108 Recombinant monoclonal antibody (Product # MA5-51526) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
MA5-51526
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4R6M4
Immunogen
Recombinant protein of human CD352/SLAMF6.
Conjugate
Form
Liquid
Concentration
0.78 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_3093811
Target Information
Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating NK receptor; CD352; Lymphocyte antigen 108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTB-A; NTBA receptor; SLAM family member 6
Gene Aliases: CD352; KAL1; KAL1b; KALI; KALIb; Ly108; NTB-A; NTBA; RGD1561848; SF2000; SLAMF6; UNQ6123/PRO20080
UniProt ID: (Human) Q96DU3, (Mouse) Q9ET39
Entrez Gene ID: (Human) 114836, (Mouse) 30925, (Rat) 498287
natural killer cell differentiation
natural killer cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
innate immune response
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
T-helper 17 cell lineage commitment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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