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Invitrogen
Ly-49I Monoclonal Antibody (YLI-90), FITC
FIGURE: 1 / 1
Ly-49I Antibody (A15413) in Flow
Frontiers in immunology 2022 -
Figure 7 (A) Ex vivo staining of CD3-NK1.1+ splenocytes from a wildtype B6 mouse with anti-NKG2A B6 (clone16a11), anti-Ly49C/I (clone 5E6), and anti-Ly49I (clone YLI-90) monoclonal antibodies. (B) Same antibodies used for the staining of splenocytes from a TAP1-KO littermate. One representative experiment out of two is shown (n=2). Particularly in the wildtype cells, the discrimination of Ly49C/I+ NK cells ... View More
Product Details
A15413
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
YLI-90
Immunogen
CHO-K1 cells transfected with the B6 allele of the Ly-49I gene, K1ra9
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5 mg/mL
Purification
purified
Storage buffer
PBS, pH 7.4
Contains
<0.1% sodium azide
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2534426
Target Information
Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5E6; Killer cell lectin-like receptor 3; killer cell lectin-like receptor subfamily A, member 9; Ly-49; Ly-49c; Ly-49I receptor; Ly49I receptor; Lymphocyte antigen 49c; Nk2.1; T-cell surface glycoprotein Ly-49C
Gene Aliases: Klra3; Ly-49c; Ly49C; Ly49I; LY49I1
UniProt ID: (Mouse) Q64329
Entrez Gene ID: (Mouse) 16640
Performance Guarantee
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