Invitrogen

Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Pacific Orange™

Product Details

RM3030

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

View 1 publication 1 publication

Flow Cytometry (Flow)

Assay-dependent

View 5 publications 5 publications

Miscellaneous PubMed (Misc)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

RB6-8C5

Immunogen

Normal murine bone marrow cells

View immunogen

Conjugate

Pacific Orange™ Pacific Orange™ Pacific Orange™

Excitation/Emission Max

400/551 nm View spectra

Form

Liquid

Concentration

0.1 mg/mL

Purification

purified

Storage buffer

PBS with 4mg/mL BSA

Contains

0.1% sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2556571

Target Information

Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody.

Cells

Olofsen PA,Stip MC,Jansen JHM,Chan C,Nederend M,Tieland RG,Tsioumpekou M,Leusen JHW

RM3030 was used in Flow cytometry/Cell sorting to show that neutrophils are efficiently depleted in the blood and tumor tissue of IMR32 tumor-bearing SCID mice, analyzed six weeks after the start of the treatment.

Thu Oct 27 00:00:00 EDT 2022

C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.

Cancer cell

Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C

RM3030 was used in Flow cytometry/Cell sorting to show that combined biallelic Cebpa and Gata2 zinc finger-1 (ZnF1) mutations cooperatively induce bilineage AEL, and that the major leukemia-initiating cell (LIC) population has a neutrophil-monocyte progenitor (NMP) phenotype.

Mon May 11 00:00:00 EDT 2020

Immune quiescence of the brain is set by astroglial connexin 43.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Boulay AC,Mazeraud A,Cisternino S,Saubaméa B,Mailly P,Jourdren L,Blugeon C,Mignon V,Smirnova M,Cavallo A,Ezan P,Avé P,Dingli F,Loew D,Vieira P,Chrétien F,Cohen-Salmon M

RM3030 was used in immunohistochemistry - paraffin section to study the role of astroglial cx43 in immune quiescence of the brain

Wed Mar 11 00:00:00 EDT 2015

Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis.

Development (Cambridge, England)

Reeh KA,Cardenas KT,Bain VE,Liu Z,Laurent M,Manley NR,Richie ER

RM3030 was used in flow cytometry to assess the contribution of Tbx1 to thymus and parathyroid development

Fri Aug 01 00:00:00 EDT 2014

Consequences of the combined loss of BOK and BAK or BOK and BAX.

Cell death & disease

Ke F,Bouillet P,Kaufmann T,Strasser A,Kerr J,Voss AK

RM3030 was used in flow cytometry to determine if Bok and Bax have any functional redundancy controlling apoptosis using knock out mice.

Thu Jun 06 00:00:00 EDT 2013

MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.

Journal of immunology (Baltimore, Md. : 1950)

McPhee CG,Sproule TJ,Shin DM,Bubier JA,Schott WH,Steinbuck MP,Avenesyan L,Morse HC,Roopenian DC

RM3030 was used in flow cytometry to determine the contributions of individual MHC class I family members to autoimmunity in two mouse models.

Tue Nov 01 00:00:00 EDT 2011

IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice.

PloS one

Botelho FM,Bauer CM,Finch D,Nikota JK,Zavitz CC,Kelly A,Lambert KN,Piper S,Foster ML,Goldring JJ,Wedzicha JA,Bassett J,Bramson J,Iwakura Y,Sleeman M,Kolbeck R,Coyle AJ,Humbles AA,Stämpfli MR

RM3030 was used in flow cytometry to review cellular and molecular mechanisms that contribute to chronic obstructive pulmonary disease pathogenesis

Fri Jul 20 00:00:00 EDT 2012

Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.

Cellular immunology

Morin J,Chimènes A,Boitard C,Berthier R,Boudaly S

RM3030 was used in flow cytometry to investigate DCs in non-obese diabetic mice.

Thu May 01 00:00:00 EDT 2003

Comparison of erythropoietic response to androgen in young and old senescence accelerated mice.

Mechanisms of ageing and development

Saitoh T,Morimoto K,Kumagai T,Tsuboi I,Aikawa S,Horie T

RM3030 was used in flow cytometry to test if the functional capacity of hemopoietic progenitor cells and the micro-environment of aged and young mice are identical.

Mon Aug 30 00:00:00 EDT 1999

Bioinformatics

Protein Aliases: Granulocyte Marker; Ly-6C1; Ly-6C2; Ly-6G; Ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6C precursor (Ly-6C); Lymphocyte antigen 6C1; Lymphocyte antigen 6C2; Lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN

View more View less

Gene Aliases: AA682074; AA959465; Gr-1; Gr1; Ly-6C; Ly-6C.2; Ly-6C1; Ly-6C2; Ly-6G; Ly6c; Ly6c1; Ly6c2; Ly6g

View more View less

UniProt ID: (Mouse) P0CW02, (Mouse) P0CW03, (Mouse) P35461

View more View less

Entrez Gene ID: (Mouse) 17067, (Mouse) 100041546, (Mouse) 546644

View more View less

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Pacific Orange™

Product Details

RM3030

Immunohistochemistry (Paraffin) (IHC (P))

Flow Cytometry (Flow)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

How to use the Panel Builder

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!