Product References
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation.
Journal of lipid research
Mukherjee P,Chattopadhyay A,Grijalva V,Dorreh N,Lagishetty V,Jacobs JP,Clifford BL,Vallim T,Mack JJ,Navab M,Reddy ST,Fogelman AM
PA5-16668 was used in Immunohistochemistry to investigate if apoA-I mimetic peptide 6F ameliorates the Western diet-mediated increase in oxidized phospholipids that cause changes in jejunum mucus, which induce dysbiosis and systemic inflammation.
Sat Jan 01 00:00:00 EST 2022
Single-Cell Analysis Reveals Unexpected Cellular Changes and Transposon Expression Signatures in the Colonic Epithelium of Treatment-Naïve Adult Crohn's Disease Patients.
Cellular and molecular gastroenterology and hepatology
Kanke M,Kennedy Ng MM,Connelly S,Singh M,Schaner M,Shanahan MT,Wolber EA,Beasley C,Lian G,Jain A,Long MD,Barnes EL,Herfarth HH,Isaacs KL,Hansen JJ,Kapadia M,Guillem JG,Feschotte C,Furey TS,Sheikh SZ,Sethupathy P
Published figure using Lysozyme polyclonal antibody (Product # PA5-16668) in Immunohistochemistry
Thu May 19 00:00:00 EDT 2022
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop.
Cell death & disease
Walter RJ,Sonnentag SJ,Munoz-Sagredo L,Merkel M,Richert L,Bunert F,Heneka YM,Loustau T,Hodder M,Ridgway RA,Sansom OJ,Mely Y,Rothbauer U,Schmitt M,Orian-Rousseau V
PA5-16668 was used in Immunohistochemistry (Paraffin) to show that CD44 promotes optimal Wnt signaling during intestinal regeneration.
Mon Feb 21 00:00:00 EST 2022
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop.
Cell death & disease
Walter RJ,Sonnentag SJ,Munoz-Sagredo L,Merkel M,Richert L,Bunert F,Heneka YM,Loustau T,Hodder M,Ridgway RA,Sansom OJ,Mely Y,Rothbauer U,Schmitt M,Orian-Rousseau V
PA5-16668 was used in Immunohistochemistry (Paraffin) to show that CD44 promotes optimal Wnt signaling during intestinal regeneration.
Mon Feb 21 00:00:00 EST 2022
Transmissible Gastroenteritis Virus Infection Promotes the Self-Renewal of Porcine Intestinal Stem Cells via Wnt/β-Catenin Pathway.
Journal of virology
Yang N,Zhang Y,Fu Y,Li Y,Yang S,Chen J,Liu G
PA5-16668 was used in Western Blot to investigate he mechanism behind the epithelium regeneration upon ransmissible gastroenteritis virus infection.
Wed Sep 28 00:00:00 EDT 2022
Aspartate Alleviates Colonic Epithelial Damage by Regulating Intestinal Stem Cell Proliferation and Differentiation via Mitochondrial Dynamics.
Molecular nutrition & food research
Wang D,Kuang Y,Wan Z,Li P,Zhao J,Zhu H,Liu Y
PA5-16668 was used in Immunohistochemistry-immunofluorescence to indicate that aspartate promotes ISC proliferation and differentiation to alleviate colonic epithelial damage by regulation of mitochondrial metabolism and dynamics.
Thu Dec 01 00:00:00 EST 2022
ILC1 drive intestinal epithelial and matrix remodelling.
Nature materials
Jowett GM,Norman MDA,Yu TTL,Rosell Arévalo P,Hoogland D,Lust ST,Read E,Hamrud E,Walters NJ,Niazi U,Chung MWH,Marciano D,Omer OS,Zabinski T,Danovi D,Lord GM,Hilborn J,Evans ND,Dreiss CA,Bozec L,Oommen OP,Lorenz CD,da Silva RMP,Neves JF,Gentleman E
PA5-16668 was used in Immunocytochemistry-immunoflourescence to develop gut organoid cocultures with type-1 innate lymphoid cells (ILC1) to dissect the impact of their accumulation in inflamed intestines.
Mon Feb 01 00:00:00 EST 2021
ILC1 drive intestinal epithelial and matrix remodelling.
Nature materials
Jowett GM,Norman MDA,Yu TTL,Rosell Arévalo P,Hoogland D,Lust ST,Read E,Hamrud E,Walters NJ,Niazi U,Chung MWH,Marciano D,Omer OS,Zabinski T,Danovi D,Lord GM,Hilborn J,Evans ND,Dreiss CA,Bozec L,Oommen OP,Lorenz CD,da Silva RMP,Neves JF,Gentleman E
PA5-16668 was used in Immunocytochemistry-immunoflourescence to develop gut organoid cocultures with type-1 innate lymphoid cells (ILC1) to dissect the impact of their accumulation in inflamed intestines.
Mon Feb 01 00:00:00 EST 2021
Morphological and histochemical characterization of the secretory epithelium in the canine lacrimal gland.
European journal of histochemistry : EJH
Yasui T,Miyata K,Nakatsuka C,Tsukise A,Gomi H
Published figure using Lysozyme polyclonal antibody (Product # PA5-16668) in Immunohistochemistry
Tue Nov 02 00:00:00 EDT 2021
Morphological and histochemical characterization of the secretory epithelium in the canine lacrimal gland.
European journal of histochemistry : EJH
Yasui T,Miyata K,Nakatsuka C,Tsukise A,Gomi H
Published figure using Lysozyme polyclonal antibody (Product # PA5-16668) in Immunohistochemistry
Tue Nov 02 00:00:00 EDT 2021
Morphological and histochemical characterization of the secretory epithelium in the canine lacrimal gland.
European journal of histochemistry : EJH
Yasui T,Miyata K,Nakatsuka C,Tsukise A,Gomi H
Published figure using Lysozyme polyclonal antibody (Product # PA5-16668) in Immunohistochemistry
Tue Nov 02 00:00:00 EDT 2021
Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Al-Shaibi AA,Abdel-Motal UM,Hubrack SZ,Bullock AN,Al-Marri AA,Agrebi N,Al-Subaiey AA,Ibrahim NA,Charles AK,Elawad M,Uhlig HH,Lo B
Published figure using Lysozyme polyclonal antibody (Product # PA5-16668) in Immunocytochemistry
Mon Mar 28 00:00:00 EDT 2022
Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Al-Shaibi AA,Abdel-Motal UM,Hubrack SZ,Bullock AN,Al-Marri AA,Agrebi N,Al-Subaiey AA,Ibrahim NA,Charles AK,Elawad M,Uhlig HH,Lo B
Published figure using Lysozyme polyclonal antibody (Product # PA5-16668) in Immunocytochemistry
Mon Mar 28 00:00:00 EDT 2022
Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy.
Cellular and molecular gastroenterology and hepatology
Das B,Okamoto K,Rabalais J,Young JA,Barrett KE,Sivagnanam M
PA5-16668 was used in Immunohistochemistry (Paraffin) to to investigate the role of epithelial cell adhesion molecule (EpCAM) in Congenital tufting enteropathy (CTE).
Fri Mar 25 00:00:00 EDT 2022
Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy.
Cellular and molecular gastroenterology and hepatology
Das B,Okamoto K,Rabalais J,Young JA,Barrett KE,Sivagnanam M
PA5-16668 was used in Immunohistochemistry (Paraffin) to to investigate the role of epithelial cell adhesion molecule (EpCAM) in Congenital tufting enteropathy (CTE).
Fri Mar 25 00:00:00 EDT 2022
MicroRNA-195 regulates Tuft cell function in the intestinal epithelium by altering translation of DCLK1.
American journal of physiology. Cell physiology
Kwon MS,Chung HK,Xiao L,Yu TX,Wang SR,Piao JJ,Rao JN,Gorospe M,Wang JY
PA5-16668 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that miR-195 suppresses the function of Tuft and Paneth cells in the small intestinal epithelium and further demonstrate that increased miR-195 disrupts Tuft cell function by inhibiting DCLK1 translation via interaction with HuR.
Tue Jun 01 00:00:00 EDT 2021
Protein Kinase D1 (PKD1) Signaling Induces Growth-Promoting Effects in Murine Enteroids.
Cellular and molecular gastroenterology and hepatology
Shimizu Y,Sinnett-Smith J,Tenggara M,Martin MG,Rozengurt E
Published figure using Lysozyme polyclonal antibody (Product # PA5-16668) in Immunocytochemistry
Fri Jul 09 00:00:00 EDT 2021
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.
Nature communications
Li X,Zhang M,Huang X,Liang W,Li G,Lu X,Li Y,Pan H,Shi L,Zhu H,Qian L,Shan B,Yuan J
PA5-16668 was used in Immunohistochemistry (Paraffin) to demonstrate the distinct roles of K612 ubiquitination in mRIPK1/K627 ubiquitination in hRIPK1 in regulating its pro-death kinase activity in response to TNFα and pro-survival activity in response to TLRs signaling.
Fri Dec 11 00:00:00 EST 2020
NAD+ supplementation rejuvenates aged gut adult stem cells.
Aging cell
Igarashi M,Miura M,Williams E,Jaksch F,Kadowaki T,Yamauchi T,Guarente L
PA5-16668 was used in Immunohistochemistry to determine the role of small molecules affecting the NAD/SIRT1/mTORC1 axis in the maintenance of the intestine during aging.
Sat Jun 01 00:00:00 EDT 2019
Ex vivo gut culture for studying differentiation and migration of small intestinal epithelial cells.
Open biology
Sun X,Fu X,Du M,Zhu MJ
PA5-16668 was used in Immunohistochemistry-immunofluorescence to develop a novel ex vivo culture system for studying the differentiation and migration of small intestinal epithelial cells.
Sun Apr 01 00:00:00 EDT 2018
Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A
PA5-16668 was used in Western Blotting to investigate the comparative structure and expression of salivary components and vesicular transport proteins in the canine major salivary glands.
Wed Nov 01 00:00:00 EDT 2017
Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A
PA5-16668 was used in Western Blotting to investigate the comparative structure and expression of salivary components and vesicular transport proteins in the canine major salivary glands.
Wed Nov 01 00:00:00 EDT 2017
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Nature
Beyaz S,Mana MD,Roper J,Kedrin D,Saadatpour A,Hong SJ,Bauer-Rowe KE,Xifaras ME,Akkad A,Arias E,Pinello L,Katz Y,Shinagare S,Abu-Remaileh M,Mihaylova MM,Lamming DW,Dogum R,Guo G,Bell GW,Selig M,Nielsen GP,Gupta N,Ferrone CR,Deshpande V,Yuan GC,Orkin SH,Sabatini DM,Yilmaz ÖH
PA5-16668 was used in immunohistochemistry - paraffin section to characterize the enhancement of tumorigenicity and stemness of intestinal progenitors due to a high-fat diet
Thu Mar 03 00:00:00 EST 2016
Characterization of antigen-presenting cells from the porcine respiratory system.
Research in veterinary science
López-Robles G,Silva-Campa E,Burgara-Estrella A,Hernández J
PA5-16668 was used in flow cytometry to describe the phenotypic and functional properties of porcine APCs in the lung , mediastinal lymph node, and bronchoalveolar lavage cells
Mon Jun 01 00:00:00 EDT 2015
The CSF-1 receptor fashions the intestinal stem cell niche.
Stem cell research
Akcora D,Huynh D,Lightowler S,Germann M,Robine S,de May JR,Pollard JW,Stanley ER,Malaterre J,Ramsay RG
PA5-16668 was used in immunocytochemistry and immunohistochemistry to study the role of CSF-1R in the maturation of Paneth cells and maintenance of the intestinal stem cell niche
Fri Mar 01 00:00:00 EST 2013
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Nature
Yilmaz ÖH,Katajisto P,Lamming DW,Gültekin Y,Bauer-Rowe KE,Sengupta S,Birsoy K,Dursun A,Yilmaz VO,Selig M,Nielsen GP,Mino-Kenudson M,Zukerberg LR,Bhan AK,Deshpande V,Sabatini DM
PA5-16668 was used in immunohistochemistry to study the role of Paneth cell mTORC1 in mediating the effects of caloric restriction on intestinal stem cells
Thu Jun 28 00:00:00 EDT 2012
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.
The Journal of cell biology
Gerbe F,van Es JH,Makrini L,Brulin B,Mellitzer G,Robine S,Romagnolo B,Shroyer NF,Bourgaux JF,Pignodel C,Clevers H,Jay P
PA5-16668 was used in immunohistochemistry - paraffin section to characterize intestinal tuft cells
Mon Mar 07 00:00:00 EST 2011
