TNF alpha Monoclonal Antibody (2TNF-H33)

protease binding cytokine activity tumor necrosis factor receptor binding protein binding identical protein binding transcription regulatory region DNA binding

protein import into nucleus, translocation negative regulation of transcription from RNA polymerase II promoter MAPK cascade activation of MAPKKK activity activation of MAPK activity positive regulation of cytokine production positive regulation of protein phosphorylation chronic inflammatory response to antigenic stimulus negative regulation of cytokine secretion involved in immune response positive regulation of chronic inflammatory response to antigenic stimulus positive regulation of humoral immune response mediated by circulating immunoglobulin glucose metabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response humoral immune response I-kappaB kinase/NF-kappaB signaling JNK cascade extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage response to virus response to salt stress positive regulation of gene expression negative regulation of gene expression negative regulation of alkaline phosphatase activity regulation of tumor necrosis factor-mediated signaling pathway negative regulation of lipid storage extracellular matrix organization osteoclast differentiation sequestering of triglyceride cortical actin cytoskeleton organization positive regulation of protein complex assembly positive regulation of fever generation lipopolysaccharide-mediated signaling pathway negative regulation of interleukin-6 production positive regulation of chemokine production positive regulation of interferon-gamma production positive regulation of interleukin-6 production positive regulation of interleukin-8 production receptor biosynthetic process positive regulation of peptidyl-serine phosphorylation tumor necrosis factor-mediated signaling pathway positive regulation of heterotypic cell-cell adhesion negative regulation of myosin-light-chain-phosphatase activity positive regulation of NF-kappaB import into nucleus positive regulation of apoptotic process positive regulation of programmed cell death regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of protein complex disassembly positive regulation of protein complex disassembly positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of MAP kinase activity protein kinase B signaling positive regulation of JUN kinase activity negative regulation of growth of symbiont in host negative regulation of viral genome replication positive regulation of chemokine biosynthetic process positive regulation of interleukin-8 biosynthetic process positive regulation of nitric oxide biosynthetic process negative regulation of fat cell differentiation negative regulation of myoblast differentiation negative regulation of osteoblast differentiation positive regulation of osteoclast differentiation positive regulation of cell adhesion positive regulation of protein kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of translational initiation by iron negative regulation of glucose import embryonic digestive tract development positive regulation of smooth muscle cell proliferation positive regulation of cytokine secretion positive regulation of phagocytosis regulation of insulin secretion defense response to Gram-positive bacterium leukocyte tethering or rolling negative regulation of lipid catabolic process regulation of immunoglobulin secretion positive regulation of membrane protein ectodomain proteolysis positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of protein transport response to glucocorticoid positive regulation of NFAT protein import into nucleus positive regulation of hair follicle development positive regulation of protein kinase B signaling positive regulation of vitamin D biosynthetic process positive regulation of calcidiol 1-monooxygenase activity epithelial cell proliferation involved in salivary gland morphogenesis regulation of branching involved in salivary gland morphogenesis negative regulation of branching involved in lung morphogenesis positive regulation of ERK1 and ERK2 cascade cellular response to amino acid stimulus cellular response to nicotine cellular response to organic cyclic compound death-inducing signaling complex assembly positive regulation of mononuclear cell migration positive regulation of podosome assembly establishment of protein localization to plasma membrane extrinsic apoptotic signaling pathway necroptotic signaling pathway positive regulation of NIK/NF-kappaB signaling positive regulation of superoxide dismutase activity regulation of establishment of endothelial barrier negative regulation of bicellular tight junction assembly positive regulation of leukocyte adhesion to vascular endothelial cell positive regulation of leukocyte adhesion to arterial endothelial cell positive regulation of protein localization to cell surface positive regulation of ceramide biosynthetic process positive regulation of blood microparticle formation positive regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of extrinsic apoptotic signaling pathway in absence of ligand