Product References
STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia.
Cell death discovery
Dinarello A,Betto RM,Diamante L,Tesoriere A,Ghirardo R,Cioccarelli C,Meneghetti G,Peron M,Laquatra C,Tiso N,Martello G,Argenton F
Published figure using HIF1A monoclonal antibody (Product # MA1-16504) in Western Blot
Wed Jul 05 00:00:00 EDT 2023
Murine Breast Cancer Radiosensitization Using Oxygen Microbubbles and Metformin: Vessels Are the Key.
International journal of molecular sciences
Drzał A,Dziurman G,Hoła P,Lechowski J,Delalande A,Swakoń J,Pichon C,Elas M
MA1-16504 was used in Immunohistochemistry to demonstrate that both two-week metformin therapy and oxygen microbubble treatment normalize abnormal cancer vasculature.
Sat Jul 29 00:00:00 EDT 2023
Developmental exposure to real-life environmental chemical mixture programs a testicular dysgenesis syndrome-like phenotype in prepubertal lambs.
Environmental toxicology and pharmacology
Elcombe CS,Monteiro A,Elcombe MR,Ghasemzadeh-Hasankolaei M,Sinclair KD,Lea R,Padmanabhan V,Evans NP,Bellingham M
MA1-16504 was used in ChIP Assay, ELISA, Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry - Free Floating, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation to provide a potential mechanism for the pathogenesis of this testicular phenotype, and TDS in humans.
Mon Aug 01 00:00:00 EDT 2022
Equine cervical remodeling during placentitis and the prepartum period: a transcriptomic approach.
Reproduction (Cambridge, England)
El-Sheikh Ali H,Scoggin KE,Ruby R,Loynachan A,Boakari Y,Fernandes C,Dini P,Fedorka CE,Loux SC,Esteller-Vico A,Ball BA
MA1-16504 was used in Immunohistochemistry to investigate the molecular mechanisms underlying cervical remodeling.
Wed May 05 00:00:00 EDT 2021
Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity.
Frontiers in veterinary science
Quiroga J,Alarcón P,Manosalva C,Teuber S,Taubert A,Hermosilla C,Hidalgo MA,Carretta MD,Burgos RA
MA1-16504 was used in Western Blotting to study D-lactate induced metabolic reprogramming, along with an inflammatory response, in bovine exposed fibroblast-like synoviocytes.
Sat Apr 03 00:00:00 EDT 2021
Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity.
Frontiers in veterinary science
Quiroga J,Alarcón P,Manosalva C,Teuber S,Taubert A,Hermosilla C,Hidalgo MA,Carretta MD,Burgos RA
MA1-16504 was used in Western Blotting to study D-lactate induced metabolic reprogramming, along with an inflammatory response, in bovine exposed fibroblast-like synoviocytes.
Sat Apr 03 00:00:00 EDT 2021
Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration.
Frontiers in pharmacology
Skovdahl HK,Gopalakrishnan S,Svendsen TD,Granlund AVB,Bakke I,Ginbot ZG,Thorsvik S,Flatberg A,Sporsheim B,Ostrop J,Mollnes TE,Sandvik AK,Bruland T
MA1-16504 was used in Immunohistochemistry (Paraffin) to indicate that an oxygen concentration similar to the in vivo epithelial cell environment is of essence in experimental pharmacology.
Tue Jun 01 00:00:00 EDT 2021
Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration.
Frontiers in pharmacology
Skovdahl HK,Gopalakrishnan S,Svendsen TD,Granlund AVB,Bakke I,Ginbot ZG,Thorsvik S,Flatberg A,Sporsheim B,Ostrop J,Mollnes TE,Sandvik AK,Bruland T
MA1-16504 was used in Immunohistochemistry (Paraffin) to indicate that an oxygen concentration similar to the in vivo epithelial cell environment is of essence in experimental pharmacology.
Tue Jun 01 00:00:00 EDT 2021
Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration.
Frontiers in pharmacology
Skovdahl HK,Gopalakrishnan S,Svendsen TD,Granlund AVB,Bakke I,Ginbot ZG,Thorsvik S,Flatberg A,Sporsheim B,Ostrop J,Mollnes TE,Sandvik AK,Bruland T
MA1-16504 was used in Immunohistochemistry (Paraffin) to indicate that an oxygen concentration similar to the in vivo epithelial cell environment is of essence in experimental pharmacology.
Tue Jun 01 00:00:00 EDT 2021
Estrogens Regulate Placental Angiogenesis in Horses.
International journal of molecular sciences
Haneda S,Dini P,Esteller-Vico A,Scoggin KE,Squires EL,Troedsson MH,Daels P,Nambo Y,Ball BA
MA1-16504 was used in Immunohistochemistry (Paraffin) to test a hypothesis that growth and expansion of the placental vascular network in the equine (Equus caballus) placenta is regulated by estrogens (estrogen family hormones).
Tue Nov 09 00:00:00 EST 2021
Estrogens Regulate Placental Angiogenesis in Horses.
International journal of molecular sciences
Haneda S,Dini P,Esteller-Vico A,Scoggin KE,Squires EL,Troedsson MH,Daels P,Nambo Y,Ball BA
MA1-16504 was used in Immunohistochemistry (Paraffin) to test a hypothesis that growth and expansion of the placental vascular network in the equine (Equus caballus) placenta is regulated by estrogens (estrogen family hormones).
Tue Nov 09 00:00:00 EST 2021
Molecular Imaging of Extracellular Tumor pH to Reveal Effects of Locoregional Therapy on Liver Cancer Microenvironment.
Clinical cancer research : an official journal of the American Association for Cancer Research
Savic LJ,Schobert IT,Peters D,Walsh JJ,Laage-Gaupp FM,Hamm CA,Tritz N,Doemel LA,Lin M,Sinusas A,Schlachter T,Duncan JS,Hyder F,Coman D,Chapiro J
MA1-16504 was used in Immunohistochemistry to establish magnetic resonance (MR)-based molecular imaging paradigms for the noninvasive monitoring of extracellular pH (pHe) as a functional surrogate biomarker for metabolic changes induced by locoregional therapy of liver cancer.
Wed Jan 15 00:00:00 EST 2020
Molecular Imaging of Extracellular Tumor pH to Reveal Effects of Locoregional Therapy on Liver Cancer Microenvironment.
Clinical cancer research : an official journal of the American Association for Cancer Research
Savic LJ,Schobert IT,Peters D,Walsh JJ,Laage-Gaupp FM,Hamm CA,Tritz N,Doemel LA,Lin M,Sinusas A,Schlachter T,Duncan JS,Hyder F,Coman D,Chapiro J
MA1-16504 was used in Immunohistochemistry to establish magnetic resonance (MR)-based molecular imaging paradigms for the noninvasive monitoring of extracellular pH (pHe) as a functional surrogate biomarker for metabolic changes induced by locoregional therapy of liver cancer.
Wed Jan 15 00:00:00 EST 2020
Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia.
Journal of cell science
Losenkova K,Zuccarini M,Karikoski M,Laurila J,Boison D,Jalkanen S,Yegutkin GG
MA1-16504 was used in Western Blotting to comprehensively assess adenosine metabolism in prostate and breast cancer cells.
Fri May 29 00:00:00 EDT 2020
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells.
Scientific reports
Baddela VS,Sharma A,Michaelis M,Vanselow J
Published figure using HIF1A monoclonal antibody (Product # MA1-16504) in Immunohistochemistry
Tue Mar 03 00:00:00 EST 2020
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells.
Scientific reports
Baddela VS,Sharma A,Michaelis M,Vanselow J
Published figure using HIF1A monoclonal antibody (Product # MA1-16504) in Immunohistochemistry
Tue Mar 03 00:00:00 EST 2020
A Nonsense Mitochondrial DNA Mutation Associates with Dysfunction of HIF1α in a Von Hippel-Lindau Renal Oncocytoma.
Oxidative medicine and cellular longevity
De Luise M,Guarnieri V,Ceccarelli C,D'Agruma L,Porcelli AM,Gasparre G
MA1-16504 was used in Immunohistochemistry to propose that the protumorigenic role of HIF1α in VHL cancers may be blunted through drugs inhibiting mitochondrial respiratory complexes, such as metformin.
Mon Mar 04 00:00:00 EST 2019
Targeting LOX-1 Inhibits Colorectal Cancer Metastasis in an Animal Model.
Frontiers in oncology
Murdocca M,Capuano R,Pucci S,Cicconi R,Polidoro C,Catini A,Martinelli E,Paolesse R,Orlandi A,Mango R,Novelli G,Di Natale C,Sangiuolo F
MA1-16504 was used in Immunohistochemistry to show the ox-LDL receptor LOX-1 can inhibit metastasis in colorectal cancer and may thus be a target to regulate tumor progression.
Sat Oct 14 00:00:00 EDT 2023
Differential but Complementary HIF1α and HIF2α Transcriptional Regulation.
Molecular therapy : the journal of the American Society of Gene Therapy
Downes NL,Laham-Karam N,Kaikkonen MU,Ylä-Herttuala S
MA1-16504 was used in Western Blotting to study the roles of HIF1a and HIF2a in transcriptional regulation.
Thu Jul 05 00:00:00 EDT 2018
Hypoxia-induced Rab11-family interacting protein 4 expression promotes migration and invasion of colon cancer and correlates with poor prognosis.
Molecular medicine reports
Wang JZ,Yang SX,Ye F,Xia XP,Shao XX,Xia SL,Zheng B,Xu CL
MA1-16504 was used in Immunohistochemistry to study the expression and significance of Rab11-family interacting proteins in colorectal cancer.
Thu Mar 01 00:00:00 EST 2018
Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma.
Oncogenesis
Murakami A,Wang L,Kalhorn S,Schraml P,Rathmell WK,Tan AC,Nemenoff R,Stenmark K,Jiang BH,Reyland ME,Heasley L,Hu CJ
MA1-16504 was used in immunohistochemistry to define distinct functional subgroups of clear cell renal cell carcinoma based on expression of BAF180
Mon Jan 16 00:00:00 EST 2017
Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells.
FEBS letters
Xu X,Tan X,Hulshoff MS,Wilhelmi T,Zeisberg M,Zeisberg EM
MA1-16504 was used in western blot to characterize the association with RASAL1 promoter hypermethylation in human coronary endothelial cells and hypoxia-induced endothelial-mesenchymal transition
Fri Apr 01 00:00:00 EDT 2016
Remote Ischemic Preconditioning Reduces Cerebral Oxidative Stress Following Hypothermic Circulatory Arrest in a Porcine Model.
Seminars in thoracic and cardiovascular surgery
Arvola O,Haapanen H,Herajärvi J,Anttila T,Puistola U,Karihtala P,Tuominen H,Anttila V,Juvonen T
MA116504 was used in immunohistochemistry to analyze oxidative stress markers after remote ischemic preconditioning in pig.
Thu Apr 13 00:00:00 EDT 2017
Prognostic impact of clinicopathological features and expression of biomarkers related to (18)F-FDG uptake in esophageal cancer.
Annals of surgical oncology
Schreurs LM,Smit JK,Pavlov K,Pultrum BB,Pruim J,Groen H,Hollema H,Plukker JT
MA1-16504 was used in immunohistochemistry - paraffin section to correlate 18-F-fluoro-deoxyglucose uptake and aggressive tumor biology in predicting outcome in esophageal cancer
Sat Nov 01 00:00:00 EDT 2014
The role of CXC-chemokine receptor CXCR2 and suppressor of cytokine signaling-3 (SOCS-3) in renal cell carcinoma.
BMC cancer
Stofas A,Levidou G,Piperi C,Adamopoulos C,Dalagiorgou G,Bamias A,Karadimou A,Lainakis GA,Papadoukakis S,Stravodimos K,Dimopoulos MA,Patsouris E,Gakiopoulou H,Korkolopoulou P
MA1-16504 was used in immunohistochemistry to study the expression and role of CXCR2 and SOCS3 in renal cell carcinoma aggresiveness and metastasis
Tue Mar 04 00:00:00 EST 2014
The role of aberrant VHL/HIF pathway elements in predicting clinical outcome to pazopanib therapy in patients with metastatic clear-cell renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Choueiri TK,Fay AP,Gagnon R,Lin Y,Bahamon B,Brown V,Rosenberg JE,Hutson TE,Baker-Neblett KL,Carpenter C,Liu Y,Pandite L,Signoretti S
MA1-16504 was used in immunohistochemistry to study the value of analysing VHL/HIF pathway components for predicting the therapeutic response of metastatic clear-cell renal cell carconima patients to pazopanib
Sun Sep 15 00:00:00 EDT 2013
Analysis of biomarker expression in severe endometriosis and determination of possibilities for targeted intraoperative imaging.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
van den Berg LL,Crane LM,van Oosten M,van Dam GM,Simons AH,Hofker HS,Bart J
MA1-16504 was used in immunohistochemistry to study the immunohistochemical expression of a range of biomarkers in order to select a panel suitable for targeted intra-operative imaging of servere endometriosis
Mon Apr 01 00:00:00 EDT 2013
Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1α (HIF-1α).
The Journal of comparative neurology
Hsieh YL,Chou LW,Chang PL,Yang CC,Kao MJ,Hong CZ
MA1-16504 was used in immunohistochemistry to study the role of low-level laser therapy in neuropathic pain alleviation and recovery from chronic constriction injury
Sat Sep 01 00:00:00 EDT 2012
Immunohistochemical study of the angiogenetic network of VEGF, HIF1α, VEGFR-2 and endothelial nitric oxide synthase (eNOS) in human breast cancer.
Pathology oncology research : POR
Kafousi M,Vrekoussis T,Tsentelierou E,Pavlakis K,Navrozoglou I,Dousias V,Sanidas E,Tsiftsis D,Georgoulias V,Stathopoulos EN
MA1-16504 was used in immunohistochemistry to study the expression of VEGF, VEGFR-2, HIF1-alpha and eNOS in invasive ductal carcinoma
Sun Jan 01 00:00:00 EST 2012
KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer.
BMC cancer
Park JJ,Jin YB,Lee YJ,Lee JS,Lee YS,Ko YG,Lee M
MA1-16504 was used in immunohistochemistry to study the mechanism by which the KAI1 metastasis-suppressor gene reduces expression of HIF-1alpha and VEGF in prostate cancer
Tue Mar 06 00:00:00 EST 2012
Astragaloside IV stimulates angiogenesis and increases hypoxia-inducible factor-1α accumulation via phosphatidylinositol 3-kinase/Akt pathway.
The Journal of pharmacology and experimental therapeutics
Zhang L,Liu Q,Lu L,Zhao X,Gao X,Wang Y
MA1-16504 was used in immunohistochemistry to study the mechanism by which astragaloside IV stimulates angiogenesis
Mon Aug 01 00:00:00 EDT 2011
Effects of cigarette smoking on hearing recovery from noise-induced temporary hearing threshold shifts in mice.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Ahn JH,Joo HS,Suh JK,Kim H,So HS,Chung JW
MA1-16504 was used in immunohistochemistry to study the effect of cigarette smoke on noise-induced hearing loss and subsequent recovery in a mouse model
Mon Aug 01 00:00:00 EDT 2011
HIF-1α and VEGF are associated with disease progression in esophageal carcinoma.
The Journal of surgical research
Takala H,Saarnio J,Wiik H,Ohtonen P,Soini Y
MA1-16504 was used in immunohistochemistry to investigate the relationship between specific gene expression and esophageal cancer progression
Sun May 01 00:00:00 EDT 2011
Expression of thioredoxin-1 and hypoxia inducible factor-1α in cerebral arteriovenous malformations: Possible role of redox regulatory factor in neoangiogenic property.
Surgical neurology international
Takagi Y,Kikuta K,Moriwaki T,Aoki T,Nozaki K,Hashimoto N,Miyamoto S
MA1-16504 was used in immunohistochemistry to study the expression and roles of thioredoxin-1 and HIF-1alpha in cerebral arteriovenous malformations
Thu Jul 14 00:00:00 EDT 2011
Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.
Cancer research
Qing G,Skuli N,Mayes PA,Pawel B,Martinez D,Maris JM,Simon MC
MA1-16504 was used in immunohistochemistry to study the role of N-Myc and hypoxia inducible factor HIF-1alpha in the regulation of neuroblastoma tumor progression
Wed Dec 15 00:00:00 EST 2010
Expression of KIT receptor tyrosine kinase in endothelial cells of juvenile brain tumors.
Brain pathology (Zurich, Switzerland)
Puputti M,Tynninen O,Pernilä P,Salmi M,Jalkanen S,Paetau A,Sihto H,Joensuu H
MA1-16504 was used in immunohistochemistry to investigate the distribution of receptor tyrosine kinase KIT in endothelial cells of young brain tumors
Thu Jul 01 00:00:00 EDT 2010
Enhancing effects of a chromone glycoside, eucryphin, isolated from Astilbe rhizomes on burn wound repair and its mechanism.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sumiyoshi M,Kimura Y
MA1-16504 was used in western blot to study the mechanisms underlying the beneficial effects of a chromone glycoside on the repair of burn wounds
Sun Aug 01 00:00:00 EDT 2010
Vasculogenic mimicry: a new prognostic sign of gastric adenocarcinoma.
Pathology oncology research : POR
Li M,Gu Y,Zhang Z,Zhang S,Zhang D,Saleem AF,Zhao X,Sun B
MA1-16504 was used in immunohistochemistry to demonstrate the prognostic significance of vasculogenic mimicry in gastric adenocarcinoma
Tue Jun 01 00:00:00 EDT 2010
Evaluation of relationship between HIF-1alpha immunoreactivity and stage, grade, angiogenic profile and proliferative index in bladder urothelial carcinomas.
International urology and nephrology
Deniz H,Karakök M,Yagci F,Güldür ME
MA1-16504 was used in immunohistochemistry to study the relationship between HIF-1alpha expression and various prognostic parameters in bladder urothelial carcinomas
Mon Mar 01 00:00:00 EST 2010
Changes in vascular permeability and expression of different angiogenic factors following anti-angiogenic treatment in rat glioma.
PloS one
Ali MM,Janic B,Babajani-Feremi A,Varma NR,Iskander AS,Anagli J,Arbab AS
MA1-16504 was used in western blot to study changes in vascular parameters, growth factors and tumor size following treatment of rat glioma with a VEGFR tyrosine kinase inhibitor
Fri Jan 15 00:00:00 EST 2010
Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE(-/-) mouse: implications for a "multihit" hypothesis of fatty liver disease.
Free radical biology & medicine
Bailey SM,Mantena SK,Millender-Swain T,Cakir Y,Jhala NC,Chhieng D,Pinkerton KE,Ballinger SW
MA1-16504 was used in immunohistochemistry to study the effects of ethanol and tobacco smoke on hepatic steatosis and hypoxia in hypercholesterolemic apoE(-/-) mice
Wed Apr 01 00:00:00 EDT 2009
Antitumor effects of 2-oxoglutarate through inhibition of angiogenesis in a murine tumor model.
Cancer science
Matsumoto K,Obara N,Ema M,Horie M,Naka A,Takahashi S,Imagawa S
MA1-16504 was used in western blot to study the mechanisms underlying the antitumor effects of 2-oxoglutarate in a murine tumor model
Tue Sep 01 00:00:00 EDT 2009
DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.
The FEBS journal
Kang MJ,Jung SM,Kim MJ,Bae JH,Kim HB,Kim JY,Park SJ,Song HS,Kim DW,Kang CD,Kim SH
MA1-16504 was used in western blot to study the role of DNA-dependent protein kinase in the accumulation of hypoxia-inducible factor-1alpha in HepG2 cells
Mon Dec 01 00:00:00 EST 2008
Cellular turnover and expression of hypoxic-inducible factor in acute acalculous and calculous cholecystitis.
Critical care (London, England)
Vakkala M,Laurila JJ,Saarnio J,Koivukangas V,Syrjälä H,Karttunen T,Soini Y,Ala-Kokko TI
MA1-16504 was used in immunohistochemistry to study epithelial cell turnover and HIF expression in acute acalculous and calculous cholecystitis
Thu May 29 00:00:00 EDT 2008
Endothelial cell KIT expression in human tumours.
The Journal of pathology
Sihto H,Tynninen O,Bützow R,Saarialho-Kere U,Joensuu H
MA1-16504 was used in immunohistochemistry to study the expression of endothelial cell KIT in a wide of human tumors
Thu Mar 01 00:00:00 EST 2007
Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk.
American journal of physiology. Cell physiology
Agrawal A,Guttapalli A,Narayan S,Albert TJ,Shapiro IM,Risbud MV
MA1-16504 was used in immunocytochemistry to study the role of HIF-1alpha in glycolytic metabolism and the expression of aggrecan in nucleus pulposus cells of the rat intervertebral disc
Wed Aug 01 00:00:00 EDT 2007
Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway.
Molecular cancer research : MCR
Pore N,Jiang Z,Shu HK,Bernhard E,Kao GD,Maity A
MA1-16504 was used in western blot to study the mechanism by which Akt1 activation can augment HIF-1alpha expression
Sat Jul 01 00:00:00 EDT 2006
Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion.
Laboratory investigation; a journal of technical methods and pathology
Zagzag D,Lukyanov Y,Lan L,Ali MA,Esencay M,Mendez O,Yee H,Voura EB,Newcomb EW
MA1-16504 was used in immunohistochemistry to examine the role of hypoxia-inducible factor 1 and VEGF in the development and progression of glioblastoma
Fri Dec 01 00:00:00 EST 2006
Understanding hypoxia-induced gene expression in early development: in vitro and in vivo analysis of hypoxia-inducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression.
Molecular and cellular biology
Kajimura S,Aida K,Duan C
MA1-16504 was used in EMSA to investigate the hypoxia-induced gene expression in early development
Wed Feb 01 00:00:00 EST 2006
Axial shortening during distraction osteogenesis leads to enhanced bone formation in a rabbit model through the HIF-1alpha/vascular endothelial growth factor system.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Mori S,Akagi M,Kikuyama A,Yasuda Y,Hamanishi C
MA1-16504 was used in immunohistochemistry to study the role of the HIF-1alpha/VEGF system in the enhanced bone formation caused by axial shortening during distraction osteogenesis in a rabbit model
Sat Apr 01 00:00:00 EST 2006
Expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival.
World journal of gastroenterology
Huang GW,Yang LY,Lu WQ
MA1-16504 was used in immunohistochemistry to study the expression of hypoxia-inducible factor 1alpha and VEGF in hepatocellular carcinoma
Mon Mar 21 00:00:00 EST 2005
HIF-1alpha-targeted pathways are activated by heat acclimation and contribute to acclimation-ischemic cross-tolerance in the heart.
Physiological genomics
Maloyan A,Eli-Berchoer L,Semenza GL,Gerstenblith G,Stern MD,Horowitz M
MA1-16504 was used in western blot to study the involvement of hypoxia-inducible factor-1alpha-targeted pathways in heat acclimation
Wed Sep 21 00:00:00 EDT 2005
HIF-VEGF-VEGFR-2, TNF-alpha and IGF pathways are upregulated in critical human skeletal muscle ischemia as studied with DNA array.
Atherosclerosis
Tuomisto TT,Rissanen TT,Vajanto I,Korkeela A,Rutanen J,Ylä-Herttuala S
MA1-16504 was used in immunohistochemistry to study the gene expression patterns in human skeletal muscle obtained from lower limbs amputated due ischemia
Sat May 01 00:00:00 EDT 2004
Bimodal effect of hypoxia in cancer: role of hypoxia inducible factor in apoptosis.
Molecular pharmaceutics
Wang Y,Pakunlu RI,Tsao W,Pozharov V,Minko T
MA1-16504 was used in western blot to study the effects of hypoxia and HIF-1alpha antisense oligonucleotides on cancer cells
Mon Jul 11 00:00:00 EDT 2005
Accumulation of hypoxia-inducible factor-1alpha in mouse inner ear by noise stimulation.
Neuroreport
Chung JW,Kang HH,Shin JE,Kim JU
MA1-16504 was used in immunohistochemistry to study the effect of noise stimulation on HIF-1alpha in mouse inner ear
Mon Oct 25 00:00:00 EDT 2004
HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin.
The EMBO journal
Morita M,Ohneda O,Yamashita T,Takahashi S,Suzuki N,Nakajima O,Kawauchi S,Ema M,Shibahara S,Udono T,Tomita K,Tamai M,Sogawa K,Yamamoto M,Fujii-Kuriyama Y
MA1-16504 was used in western blot to investigate the function of HLF in a mouse model of retinopathy of prematurity
Mon Mar 03 00:00:00 EST 2003
Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.
Cancer research
Ma W,Tessarollo L,Hong SB,Baba M,Southon E,Back TC,Spence S,Lobe CG,Sharma N,Maher GW,Pack S,Vortmeyer AO,Guo C,Zbar B,Schmidt LS
MA1-16504 was used in immunohistochemistry to study the effects of conditional inactivation of the VHL gene in mice
Mon Sep 01 00:00:00 EDT 2003
Clinical benefit of prostaglandin E1-treatment of patients with ischemic heart disease: stimulation of therapeutic angiogenesis in vital and infarcted myocardium.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mehrabi MR,Serbecic N,Tamaddon F,Pacher R,Horvath R,Mall G,Glogar HD
MA1-16504 was used in immunohistochemistry to investigate the therapeutic efficacy of prostaglandin E1 in ischemic heart disease
Tue Feb 10 00:00:00 EST 2004
Clinical and experimental evidence of prostaglandin E1-induced angiogenesis in the myocardium of patients with ischemic heart disease.
Cardiovascular research
Mehrabi MR,Serbecic N,Tamaddon F,Kaun C,Huber K,Pacher R,Wild T,Mall G,Wojta J,Glogar HD
MA1-16504 was used in immunohistochemistry to investigate the influence of PGE-1 on myocardic angiogenesis in patients with ischemic heart disease
Fri Nov 01 00:00:00 EST 2002
Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.
Environmental health perspectives
Cangul H,Salnikow K,Yee H,Zagzag D,Commes T,Costa M
MA1-16504 was used in immunohistochemistry to study the role of HIF-1/hypoxia-related protein Cap43 overexpression in cancer cells
Tue Oct 01 00:00:00 EDT 2002
Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis.
Cell biology and toxicology
Cangul H,Salnikow K,Yee H,Zagzag D,Commes T,Costa M
MA1-16504 was used in western blot to study the enhanced expression of the novel protein Cap24 in human cancer cells and its potential diagnostic value
Tue Nov 19 00:00:00 EST 2002
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes.
The Journal of biological chemistry
Miyazaki K,Kawamoto T,Tanimoto K,Nishiyama M,Honda H,Kato Y
MA1-16504 was used in EMSA to investigate the existence of hypoxia response elements in the promoter of DEC1 and DEC2
Fri Dec 06 00:00:00 EST 2002
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes.
Nature medicine
Kim MS,Kwon HJ,Lee YM,Baek JH,Jang JE,Lee SW,Moon EJ,Kim HS,Lee SK,Chung HY,Kim CW,Kim KW
MA1-16504 was used in western blot to study the role of histone deacetylases in the regulation of hypoxia-induced angiogenesis
Sun Apr 01 00:00:00 EST 2001
Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.
The Journal of biological chemistry
Yamashita K,Discher DJ,Hu J,Bishopric NH,Webster KA
MA1-16504 was used in EMSA to study the role of HIF-1, AP-1, GATA-2, and p300/CBP in the regulation of the endothelin-1 gene by hypoxia
Fri Apr 20 00:00:00 EDT 2001
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.
Cancer research
Salnikow K,Costa M,Figg WD,Blagosklonny MV
MA1-16504 was used in western blot to investigate the role of the hypoxia-responsive genes in tumor growth and metastasis
Sun Oct 15 00:00:00 EDT 2000