Product References
Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model.
Communications biology
Custodio RJP,Kim HJ,Kim J,Ortiz DM,Kim M,Buctot D,Sayson LV,Lee HJ,Kim BN,Yi EC,Cheong JH
MA3-071 was used in Immunohistochemistry-immunofluorescence to show new markers specific to the ADHD-PI presentation, converging with the ancient and evolutionary Wnt signaling pathways crucial for cell fate determination, migration, polarity, and neural patterning during neurodevelopment.
Mon Jan 16 00:00:00 EST 2023
The Bcl-2/Bcl-xL Inhibitor ABT-263 Attenuates Retinal Degeneration by Selectively Inducing Apoptosis in Senescent Retinal Pigment Epithelial Cells.
Molecules and cells
Ryu W,Park CW,Kim J,Lee H,Chung H
MA3-071 was used in Immunocytochemistry-immunofluorescence to suggest that ABT-263, which removes senescent RPE cells through its senolytic effect, has the potential to be the first orally administered senolytic drug for the treatment of AMD.
Mon Jul 31 00:00:00 EDT 2023
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis.
JCI insight
Szabó V,Csákány-Papp N,Görög M,Madácsy T,Varga Á,Kiss A,Tél B,Jójárt B,Crul T,Dudás K,Bagyánszki M,Bódi N,Ayaydin F,Jee S,Tiszlavicz L,Stauderman KA,Hebbar S,Pallagi P,Maléth J
MA3-071 was used in Flow cytometry/Cell sorting to suggest that the overactivation of Orai1 is a crucial pathogenetic event in the progression of early CP and that inhibition of Orai1 could prevent the development of end-stage CP.
Mon Jul 10 00:00:00 EDT 2023
ST6Gal-I-mediated sialylation of the epidermal growth factor receptor modulates cell mechanics and enhances invasion.
The Journal of biological chemistry
Rao TC,Beggs RR,Ankenbauer KE,Hwang J,Ma VP,Salaita K,Bellis SL,Mattheyses AL
MA3-071 was used in Immunocytochemistry to explore the mechanisms of ST6Gal-I and epidermal growth factor receptor signalling on cell activity.
Fri Apr 01 00:00:00 EDT 2022
ST6Gal-I-mediated sialylation of the epidermal growth factor receptor modulates cell mechanics and enhances invasion.
The Journal of biological chemistry
Rao TC,Beggs RR,Ankenbauer KE,Hwang J,Ma VP,Salaita K,Bellis SL,Mattheyses AL
MA3-071 was used in Immunocytochemistry to explore the mechanisms of ST6Gal-I and epidermal growth factor receptor signalling on cell activity.
Fri Apr 01 00:00:00 EDT 2022
Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Zhang H,Puviindran V,Nadesan P,Ding X,Shen L,Tang YJ,Tsushima H,Yahara Y,Ban GI,Zhang GF,Karner CM,Alman BA
MA3-071 was used in Immunohistochemistry-immunofluorescence to demonstrate that glutaminase-mediated glutamine metabolism played distinct roles in enchondromas and chondrosarcomas with IDH1 or IDH2 mutations.
Sun May 01 00:00:00 EDT 2022
Dietary Protein Source and Litter Condition Alter Broiler Chicken Intestinal Macrophage and Mitotically Active Cell Populations.
Frontiers in veterinary science
Keel AJ,Calderon AJ,Tejeda OJ,Starkey JD,Starkey CW
MA3-071 was used in Immunocytochemistry-immunofluorescence to indicate dietary protein source and litter condition may impact the physiology of the broiler small intestine, though additional work with this model is necessary to understand the underlying mechanisms.
Sat Jul 16 00:00:00 EDT 2022
ERRγ Ligand Regulates Adult Neurogenesis and Depression-like Behavior in a LRRK2-G2019S-associated Young Female Mouse Model of Parkinson's Disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Kim HI,Lim J,Choi HJ,Kim SH,Choi HJ
MA3-071 was used in Immunohistochemistry to suggest ERRγ as a novel therapeutic target for PD-associated depression by modulating adult neurogenesis and BDNF/TrkB signaling.
Fri Jul 01 00:00:00 EDT 2022
IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells.
Developmental cell
Zhang X,Luo S,Wang M,Huang Q,Fang W,Li J,Liu T,Zhang Y,Deng Z,Liu CL,Guan S,Ayala JE,Flavell RA,Kulkarni RN,Libby P,Guo J,Liu Z,Shi GP
MA3-071 was used in BrdU pulse labeling to report that IL18 is expressed on islet α cells, NCC on β cells, and IL18r on acinar cells in human and mouse pancreases.
Mon Jun 20 00:00:00 EDT 2022
Combined Maternal and Post-Hatch Dietary Supplementation of 25-Hydroxycholecalciferol Alters Early Post-Hatch Broiler Chicken Duodenal Macrophage and Crypt Cell Populations and Their Mitotic Activity.
Frontiers in veterinary science
Leiva SF,Avila LP,Abascal-Ponciano GA,Flees JJ,Sweeney KM,Wilson JL,Starkey JD,Starkey CW
MA3-071 was used in Immunohistochemistry to indicate that combined MDIET and PDIET 25OHD3 supplementation may alter early post-hatch duodenal development and innate immunity.
Sat Apr 30 00:00:00 EDT 2022
Effect of combined maternal and post-hatch dietary 25-hydroxycholecalciferol supplementation on broiler chicken Pectoralis major muscle growth characteristics and satellite cell mitotic activity.
Journal of animal science
Avila LP,Leiva SF,Abascal-Ponciano GA,Flees JJ,Sweeney KM,Wilson JL,Meloche KJ,Turner BJ,Litta G,Waguespack-Levy AM,Pokoo-Aikins A,Starkey CW,Starkey JD
MA3-071 was used in Immunohistochemistry-immunofluorescence to evaluate the effect of combined maternal and post-hatch dietary 25OHD3 supplementation on the growth and SC mitotic activity of the Pectoralis major (PM) muscles in broiler chickens.
Mon Aug 01 00:00:00 EDT 2022
Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas.
Frontiers in cell and developmental biology
Luo Z,Dong X,Yu J,Xia Y,Berry KP,Rao R,Xu L,Xue P,Chen T,Lin Y,Yu J,Huang G,Li H,Zhou W,Lu QR
MA3-071 was used in Immunocytochemistry to investigate the contribution of genomic and transcriptomic alterations to the risk of malignant medulloblastoma in the Chinese populations.
Thu Jul 15 00:00:00 EDT 2021
iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma.
Investigative ophthalmology & visual science
Sui S,Yu H,Wang X,Wang W,Yang X,Pan X,Zhou Q,Xin C,Du R,Wu S,Zhang J,Cao Q,Wang N,Kuehn MH,Zhu W
MA3-071 was used in Immunocytochemistry to investigate whether signaling via gap junctions is involved in trabecular meshwork cellularity.
Mon Aug 02 00:00:00 EDT 2021
Oxidative Stress, Mutations and Chromosomal Aberrations Induced by In Vitro and In Vivo Exposure to Furan.
International journal of molecular sciences
Russo MT,De Luca G,Palma N,Leopardi P,Degan P,Cinelli S,Pepe G,Mosesso P,Di Carlo E,Sorrentino C,Musiani P,Crebelli R,Bignami M,Dogliotti E
MA3-071 was used in Immunohistochemistry to address the mutagenic and clastogenic activity of furan and its prime reactive metabolite cis-2 butene-1,4-dial (BDA) in mammalian cells in culture and in mouse animal models in a search for DNA lesions responsible of these effects.
Tue Sep 07 00:00:00 EDT 2021
Oxidative Stress, Mutations and Chromosomal Aberrations Induced by In Vitro and In Vivo Exposure to Furan.
International journal of molecular sciences
Russo MT,De Luca G,Palma N,Leopardi P,Degan P,Cinelli S,Pepe G,Mosesso P,Di Carlo E,Sorrentino C,Musiani P,Crebelli R,Bignami M,Dogliotti E
MA3-071 was used in Immunohistochemistry to address the mutagenic and clastogenic activity of furan and its prime reactive metabolite cis-2 butene-1,4-dial (BDA) in mammalian cells in culture and in mouse animal models in a search for DNA lesions responsible of these effects.
Tue Sep 07 00:00:00 EDT 2021
SAG therapy restores bone growth and reduces enchondroma incidence in a model of skeletal chondrodysplasias caused by Ihh deficiency.
Molecular therapy. Methods & clinical development
Li X,Yang S,Chinipardaz Z,Koyama E,Yang S
MA3-071 was used in Immunocytochemistry to establish a mouse model of human skeletal dysplasia induced by Indian hedgehog (Ihh) gene mutations.
Fri Dec 10 00:00:00 EST 2021
SAG therapy restores bone growth and reduces enchondroma incidence in a model of skeletal chondrodysplasias caused by Ihh deficiency.
Molecular therapy. Methods & clinical development
Li X,Yang S,Chinipardaz Z,Koyama E,Yang S
MA3-071 was used in Immunocytochemistry to establish a mouse model of human skeletal dysplasia induced by Indian hedgehog (Ihh) gene mutations.
Fri Dec 10 00:00:00 EST 2021
Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice.
Alzheimer's research & therapy
Son G,Yoo SJ,Kang S,Rasheed A,Jung DH,Park H,Cho B,Steinbusch HWM,Chang KA,Suh YH,Moon C
MA3-071 was used in Immunohistochemistry to show that partial olfactory dysfunction closely associated with peripheral OSN's loss could be a leading cause of AD-related hyposmia, a characteristic of early AD.
Mon Jan 04 00:00:00 EST 2021
Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells.
Pharmaceutics
Kim HJ,Kim TJ,Kim YG,Seong C,Cho JH,Kim W,Lee KH,Kim DY
MA3-071 was used in Immunocytochemistry to test the possibility that finasteride has the potential to be developed as an anti-glioblastoma drug and determine the detailed intracellular mechanisms of finasteride in glioblastoma cells.
Mon Sep 06 00:00:00 EDT 2021
Reactive astrocytes facilitate vascular repair and remodeling after stroke.
Cell reports
Williamson MR,Fuertes CJA,Dunn AK,Drew MR,Jones TA
MA3-071 was used in Immunohistochemistry to show that reactive astrocytes are crucial for vascular repair and remodeling after ischemic stroke in mice.
Tue Apr 27 00:00:00 EDT 2021
Ciliary IFT80 is essential for intervertebral disc development and maintenance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li X,Yang S,Han L,Mao K,Yang S
MA3-071 was used in Flow cytometry/Cell sorting to demonstrate that ciliary IFT80 is important for the maintenance of intervertebral disc cell organisation and function.
Fri May 01 00:00:00 EDT 2020
Pancreatobiliary Diversion in the Mouse.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes
Chen X,Qiu S,Li Q,Hu L,Yao C,Xu X,Wang F
MA3-071 was used in Immunohistochemistry to show how PBD may be combined with the cancer model to study the role of CCK in the molecular biology of pancreatic cancer.
Fri Oct 29 00:00:00 EDT 2021
A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors.
Cells
Santhanam A,Shihabeddin E,Atkinson JA,Nguyen D,Lin YP,O'Brien J
MA3-071 was used in Immunohistochemistry-wholemount to develop a zebrafish model of Retinitis Pigmentosa that displays ongoing regeneration.
Tue Oct 06 00:00:00 EDT 2020
A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors.
Cells
Santhanam A,Shihabeddin E,Atkinson JA,Nguyen D,Lin YP,O'Brien J
MA3-071 was used in Immunohistochemistry-wholemount to develop a zebrafish model of Retinitis Pigmentosa that displays ongoing regeneration.
Tue Oct 06 00:00:00 EDT 2020
Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival.
Cells
Kang M,Kim HJ,Kim TJ,Byun JS,Lee JH,Lee DH,Kim W,Kim DY
MA3-071 was used in Immunocytochemistry to show that the Fubp1 protein level was enriched in the S phase and we identified that Fubp1 deficiency altered cell cycle progression, especially in the S phase, by downregulating the mRNA expression levels of Ccna genes encoding cyclin A.
Thu May 28 00:00:00 EDT 2020
Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival.
Cells
Kang M,Kim HJ,Kim TJ,Byun JS,Lee JH,Lee DH,Kim W,Kim DY
MA3-071 was used in Immunocytochemistry to show that the Fubp1 protein level was enriched in the S phase and we identified that Fubp1 deficiency altered cell cycle progression, especially in the S phase, by downregulating the mRNA expression levels of Ccna genes encoding cyclin A.
Thu May 28 00:00:00 EDT 2020
Dentate Gyrus Proliferative Responses After Traumatic Brain Injury and Binge Alcohol in Adult Rats.
Neuroscience insights
Ton ST,Adamczyk NS,Gerling JP,Vaagenes IC,Wu JY,Hsu K,O'Brien TE,Tsai SY,Kartje GL
MA3-071 was used in Immunohistochemistry, Immunocytochemistry to determine the effects of binge alcohol prior to traumatic brain injury and whether it affects the proliferative response in the hippocampal dentate gyrus.
Mon Apr 18 00:00:00 EDT 2022
Dentate Gyrus Proliferative Responses After Traumatic Brain Injury and Binge Alcohol in Adult Rats.
Neuroscience insights
Ton ST,Adamczyk NS,Gerling JP,Vaagenes IC,Wu JY,Hsu K,O'Brien TE,Tsai SY,Kartje GL
MA3-071 was used in Immunohistochemistry, Immunocytochemistry to determine the effects of binge alcohol prior to traumatic brain injury and whether it affects the proliferative response in the hippocampal dentate gyrus.
Mon Apr 18 00:00:00 EDT 2022
Subventricular zone neural precursor cell responses after traumatic brain injury and binge alcohol in male rats.
Journal of neuroscience research
Ton ST,Tsai SY,Vaagenes IC,Glavin K,Wu J,Hsu J,Flink HM,Nockels D,O'Brien TE,Kartje GL
Published figure using BrdU monoclonal antibody (Product # MA3-071) in Immunofluorescence
Wed May 01 00:00:00 EDT 2019
FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis.
Developmental cell
Ji S,Liu Q,Zhang S,Chen Q,Wang C,Zhang W,Xiao C,Li Y,Nian C,Li J,Li J,Geng J,Hong L,Xie C,He Y,Chen X,Li X,Yin ZY,You H,Lin KH,Wu Q,Yu C,Johnson RL,Wang L,Chen L,Wang F,Zhou D
MA3-071 was used in Immunohistochemistry to find that circulating enterohepatic FGF15 stimulates hepatic receptor FGFR4 to recruit and phosphorylate NF2, which relieves the inhibitory effect of Raf on the Hippo kinases Mst1/2, thereby switching FGFR4's role from pro-oncogenic to anti-tumor signaling.
Mon Feb 25 00:00:00 EST 2019
JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche.
Molecular psychiatry
Mohammad H,Marchisella F,Ortega-Martinez S,Hollos P,Eerola K,Komulainen E,Kulesskaya N,Freemantle E,Fagerholm V,Savontaus E,Rauvala H,Peterson BD,van Praag H,Coffey ET
MA3071 was used in immunohistochemistry - free floating to report a role for JNK in the hippocampal neurogenic niche and anxiety behavior
Thu Feb 01 00:00:00 EST 2018
Tet1 overexpression leads to anxiety-like behavior and enhanced fear memories via the activation of calcium-dependent cascade through Egr1 expression in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kwon W,Kim HS,Jeong J,Sung Y,Choi M,Park S,Lee J,Jang S,Kim SH,Lee S,Kim MO,Ryoo ZY
MA3-071 was used in Immunohistochemistry to study the effects of Tet1 overexpression in the brain.
Mon Jan 01 00:00:00 EST 2018
The RacGAP β-Chimaerin is essential for cerebellar granule cell migration.
Scientific reports
Estep JA,Wong W,Wong YE,Loui BM,Riccomagno MM
MA3-071 was used in Immunohistochemistry to suggest a role for Β-chimaerin as an intracellular mediator of Cerebellar Granule Cell radial migration.
Fri Jan 12 00:00:00 EST 2018
Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.
Cancer cell
Zhang S,Chen Q,Liu Q,Li Y,Sun X,Hong L,Ji S,Liu C,Geng J,Zhang W,Lu Z,Yin ZY,Zeng Y,Lin KH,Wu Q,Li Q,Nakayama K,Nakayama KI,Deng X,Johnson RL,Zhu L,Gao D,Chen L,Zhou D
MA3-071 was used in Immunohistochemistry to study the role of Yap in promoting the diploid-polyploid conversion and polyploid cell growth through the Akt-Skp2 axis.
Mon May 08 00:00:00 EDT 2017
Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes.
Experimental cell research
Mytych J,Wos I,Solek P,Koziorowski M
MA3071 was used in immunocytochemistry to show that ROS-induced DNA damage reduces metabolic activity, inhibits proliferation, and induces cell cycle arrest followed by activation of p16-, p21-, and p27- mediated DNA damage response pathways, premature senescence, and apoptosis induction
Sun Jan 15 00:00:00 EST 2017
R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature.
Nature communications
Li F,Sawada J,Komatsu M
MA3-071 was used in Blocking experiments to identify a role for Akt in lumenogenesis and the significance of the R-Ras-Akt signaling for the patency of regenerating blood vessels.
Thu Nov 23 00:00:00 EST 2017
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Cell
Herrtwich L,Nanda I,Evangelou K,Nikolova T,Horn V,Erny D,Stefanowski J,Rogell L,Klein C,Gharun K,Follo M,Seidl M,Kremer B,Münke N,Senges J,Fliegauf M,Aschman T,Pfeifer D,Sarrazin S,Sieweke MH,Wagner D,Dierks C,Haaf T,Ness T,Zaiss MM,Voll RE,Deshmukh SD,Prinz M,Goldmann T,Hölscher C,Hauser AE,Lopez-Contreras AJ,Grün D,Gorgoulis V,Diefenbach A,Henneke P,Triantafyllopoulou A
MA3-071 was used in Immunocytochemistry-immunoflourescence to study the molecular programs that control differentiation of macrophage populations in response to chronic stimulus.
Thu Nov 17 00:00:00 EST 2016
Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration.
Journal of cell science
Polusani SR,Kalmykov EA,Chandrasekhar A,Zucker SN,Nicholson BJ
MA3-071 was used in Immunocytochemistry-immunoflourescence to show that expression of Cx26 in HeLa cells specifically enhances cell motility in scrape wounding and sparse culture models.
Thu Dec 01 00:00:00 EST 2016
Highly efficient generation of glutamatergic/cholinergic NT2-derived postmitotic human neurons by short-term treatment with the nucleoside analogue cytosine β-D-arabinofuranoside.
Stem cell research
González-Burguera I,Ricobaraza A,Aretxabala X,Barrondo S,García del Caño G,López de Jesús M,Sallés J
MA3-071 was used in Immunofluorescence to further reinforce the notion NT2 cells are a versatile source of neuronal phenotypes and provide a new encouraging platform for studying mechanisms of neuronal differentiation and for exploring neuronal replacement strategies.
Tue Mar 01 00:00:00 EST 2016
Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats.
Frontiers in neuroscience
Shepherd DJ,Tsai SY,O'Brien TE,Farrer RG,Kartje GL
MA3071 was used in immunohistochemistry - free floating to test if anti-Nogo-A treatment increases hippocampal neurogenesis after stroke
Thu Jul 27 00:00:00 EDT 2023
PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress.
PLoS genetics
Jo U,Cai W,Wang J,Kwon Y,D'Andrea AD,Kim H
MA3071 was used in flow cytometry to discover that SDE2 is a genome surveillance factor regulated by proliferating cell nuclear antigen
Thu Dec 01 00:00:00 EST 2016
The antibodies against 5-bromo-2'-deoxyuridine specifically recognize trifluridine incorporated into DNA.
Scientific reports
Kitao H,Morodomi Y,Niimi S,Kiniwa M,Shigeno K,Matsuoka K,Kataoka Y,Iimori M,Tokunaga E,Saeki H,Oki E,Maehara Y
MA3-071 was used in flow cytometry to analyze the specific recognition of trifluridine incorporated into DNA by antibodies against 5-bromo-2'-deoxyuridine
Tue May 03 00:00:00 EDT 2016
Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration.
Breast cancer research : BCR
Bray K,Gillette M,Young J,Loughran E,Hwang M,Sears JC,Vargo-Gogola T
MA3-071 was used in immunohistochemistry to study the role of cell migration in the mechanism by which overexpression of Cdc42 promotes developing mammary gland hyperbranching
Thu Sep 11 00:00:00 EDT 2014
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood
He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML
Published figure using BrdU monoclonal antibody (Product # MA3-071) in Immunofluorescence
Thu Oct 11 00:00:00 EDT 2012
Atorvastatin and whisker stimulation synergistically enhance angiogenesis in the barrel cortex of rats following focal ischemia.
Neuroscience letters
Zhang Y,Huang S,Wang B,Sun B,Li W,Lu X,Ding X
MA3-071 was used in immunohistochemistry to study the synergistic effects of atorvastatin and whisker stimulation on rat barrel cortex angiogenesis following ischemia
Thu Sep 13 00:00:00 EDT 2012
Dual mechanism for the translation of subgenomic mRNA from Sindbis virus in infected and uninfected cells.
PloS one
Sanz MA,Castelló A,Ventoso I,Berlanga JJ,Carrasco L
MA3-071 was used in immunocytochemistry to study the translation of sub-genomic DNA in Sindbis-infected and -uninfected BHK cells and the different mechanisms utilized
Mon Jun 15 00:00:00 EDT 2009
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America
Cheshier SH,Morrison SJ,Liao X,Weissman IL
MA3-071 was used in immunocytochemistry to study the proliferation and cell cycle kinetics of long-term self-renewing murine long-term hematopoietic stem cells.
Tue Mar 16 00:00:00 EST 1999
