Product References
Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration.
Cell
Jia Y,Mu JC,Ackerman SL
MA5-13446 was used in immunoprecipitation to study the role of a mutation of a U2 snRNA gene in global disruption of alternative splicing and neurodegeneration
Fri Jan 20 00:00:00 EST 2012
PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.
Human molecular genetics
Tanackovic G,Ransijn A,Thibault P,Abou Elela S,Klinck R,Berson EL,Chabot B,Rivolta C
MA5-13446 was used in immunoprecipitation to investigate the associates of PRPF mutations with defects in pre-mRNA splicing in patients with retinitis pigmentosa
Wed Jun 01 00:00:00 EDT 2011
Functional association of the Microprocessor complex with the spliceosome.
Molecular and cellular biology
Kataoka N,Fujita M,Ohno M
MA5-13446 was used in immunoprecipitation to investigate the molecular basis for intronic miRNA processing
Mon Jun 01 00:00:00 EDT 2009
The inability of fully grown germinal vesicle stage oocyte cytoplasm to transcriptionally silence transferred transcribing nuclei.
Histochemistry and cell biology
Fulka H,Novakova Z,Mosko T,Fulka J
MA5-13446 was used in immunocytochemistry to evaluate the utility of fully grown germinal vesicle stage oocyte cytoplasm in somatic cell nuclear transfer experiments
Thu Oct 01 00:00:00 EDT 2009
Restoration of SMN function: delivery of a trans-splicing RNA re-directs SMN2 pre-mRNA splicing.
Molecular therapy : the journal of the American Society of Gene Therapy
Coady TH,Shababi M,Tullis GE,Lorson CL
MA5-13446 was used in immunoprecipitation to study the restoration of survival motor neuron function by a redirection of SMN2 pre-mRNA splicing
Wed Aug 01 00:00:00 EDT 2007
Arginine methyltransferase Capsuleen is essential for methylation of spliceosomal Sm proteins and germ cell formation in Drosophila.
Development (Cambridge, England)
Anne J,Ollo R,Ephrussi A,Mechler BM
MA5-13446 was used in immunocytochemistry to study the essential role of protein arginine methyltransferase in protein localization in germ cells
Mon Jan 01 00:00:00 EST 2007
Mutations in splicing factor PRPF3, causing retinal degeneration, form detrimental aggregates in photoreceptor cells.
Human molecular genetics
Comitato A,Spampanato C,Chakarova C,Sanges D,Bhattacharya SS,Marigo V
MA5-13446 was used in immunohistochemistry to investigate the role of mutations in splicing factor PRPF3 in retinal degeneration of photoreceptor cells
Sun Jul 15 00:00:00 EDT 2007
Myosin16b: The COOH-tail region directs localization to the nucleus and overexpression delays S-phase progression.
Cell motility and the cytoskeleton
Cameron RS,Liu C,Mixon AS,Pihkala JP,Rahn RJ,Cameron PL
MA5-13446 was used in immunohistochemistry to study the role of the myosin16b COOH-tail region in localization to the nucleus and S-phase progression
Mon Jan 01 00:00:00 EST 2007
Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly.
The Journal of biological chemistry
Carissimi C,Saieva L,Baccon J,Chiarella P,Maiolica A,Sawyer A,Rappsilber J,Pellizzoni L
MA5-13446 was used in immunoprecipitation to investigate the role of gemin8 in the survival motor neuron complex and its function in small nuclear ribonucleoprotein assembly
Fri Mar 24 00:00:00 EST 2006
Subcellular localization of protein kinase C delta and epsilon affects transcriptional and post-transcriptional processes in four-cell mouse embryos.
Reproduction (Cambridge, England)
Dehghani H,Reith C,Hahnel AC
MA5-13446 was used in immunohistochemistry to study the role of protein kinase C delta and epsilon subcellular localization on transcriptional and post-transcriptional processes in mouse preimplantation development
Sat Oct 01 00:00:00 EDT 2005
Tim50a, a nuclear isoform of the mitochondrial Tim50, interacts with proteins involved in snRNP biogenesis.
BMC cell biology
Xu H,Somers ZB,Robinson ML,Hebert MD
MA5-13446 was used in immunocytochemistry to study the role of Tim50a in snRNP biogenesis.
Mon Jul 11 00:00:00 EDT 2005
A key role for stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules.
Journal of cell science
Metz A,Soret J,Vourc'h C,Tazi J,Jolly C
MA5-13446 was used in immunocytochemistry to study the role of stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules
Wed Sep 01 00:00:00 EDT 2004
ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia.
Molecular biology of the cell
Polak PE,Simone F,Kaberlein JJ,Luo RT,Thirman MJ
MA5-13446 was used in immunocytochemistry to study the disruption of Cajal body components ELL and EAF1 in MLL-ELL leukemia
Tue Apr 01 00:00:00 EST 2003
pICln inhibits snRNP biogenesis by binding core spliceosomal proteins.
Molecular and cellular biology
Pu WT,Krapivinsky GB,Krapivinsky L,Clapham DE
MA5-13446 was used in immunoprecipitation to study the mechanism for the inhibitory effect of pICln on snRNP biogenesis
Tue Jun 01 00:00:00 EDT 1999