Product References
Tumor-associated tissue eosinophilia promotes angiogenesis and metastasis in head and neck squamous cell carcinoma.
Neoplasia (New York, N.Y.)
Lee TL,Chen TH,Kuo YJ,Lan HY,Yang MH,Chu PY
MA5-13473 was used in Immunohistochemistry-immunofluorescence to investigate how tumor-associated tissue eosinophilia (TATE) can influence tumor behavior and tumor microenvironment in head and neck squamous cell carcinoma.
Sun Jan 01 00:00:00 EST 2023
Protocol for investigating tertiary lymphoid structures in human and murine fixed tissue sections using Opal™-TSA multiplex immunohistochemistry.
STAR protocols
Quigley LT,Pang L,Tavancheh E,Ernst M,Behren A,Huynh J,Da Gama Duarte J
MA5-13473 was used in Flow Cytometry, Immunohistochemistry (Paraffin) to identify immature and mature tertiary lymphoid structures (TLSs).
Fri Mar 17 00:00:00 EDT 2023
An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer.
Cell reports. Medicine
Johnson BE,Creason AL,Stommel JM,Keck JM,Parmar S,Betts CB,Blucher A,Boniface C,Bucher E,Burlingame E,Camp T,Chin K,Eng J,Estabrook J,Feiler HS,Heskett MB,Hu Z,Kolodzie A,Kong BL,Labrie M,Lee J,Leyshock P,Mitri S,Patterson J,Riesterer JL,Sivagnanam S,Somers J,Sudar D,Thibault G,Weeder BR,Zheng C,Nan X,Thompson RF,Heiser LM,Spellman PT,Thomas G,Demir E,Chang YH,Coussens LM,Guimaraes AR,Corless C,Goecks J,Bergan R,Mitri Z,Mills GB,Gray JW
MA5-13473 was used in Flow Cytometry to present illustrative examples of how integrative analyses of data reveal potential mechanisms of response and resistance and suggest novel therapeutic vulnerabilities.
Tue Feb 15 00:00:00 EST 2022
Role of the thymus in spontaneous development of a multi-organ autoimmune disease in human immune system mice.
Journal of autoimmunity
Khosravi-Maharlooei M,Li H,Hoelzl M,Zhao G,Ruiz A,Misra A,Li Y,Teteloshvili N,Nauman G,Danzl N,Ding X,Pinker EY,Obradovic A,Yang YG,Iuga A,Creusot RJ,Winchester R,Sykes M
MA5-13473 was used in Immunohistochemistry to evaluate the role of the thymus in development of multi-organ autoimmunity in human immune system (HIS) mice.
Sat May 01 00:00:00 EDT 2021
Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial.
Journal for immunotherapy of cancer
Klein O,Kee D,Gao B,Markman B,da Gama Duarte J,Quigley L,Jackett L,Linklater R,Strickland A,Scott C,Mileshkin L,Palmer J,Carlino M,Behren A,Cebon J
MA5-13473 was used in Immunohistochemistry to show that ipilimumab and nivolumab combination treatment has significant clinical activity with a favorable safety profile across a range of advanced rare gynecological malignancies and warrants further investigation in these tumor types.
Mon Nov 01 00:00:00 EDT 2021
Combination immunotherapy with nivolumab and ipilimumab in patients with rare gynecological malignancies: results of the CA209-538 clinical trial.
Journal for immunotherapy of cancer
Klein O,Kee D,Gao B,Markman B,da Gama Duarte J,Quigley L,Jackett L,Linklater R,Strickland A,Scott C,Mileshkin L,Palmer J,Carlino M,Behren A,Cebon J
MA5-13473 was used in Immunohistochemistry to show that ipilimumab and nivolumab combination treatment has significant clinical activity with a favorable safety profile across a range of advanced rare gynecological malignancies and warrants further investigation in these tumor types.
Mon Nov 01 00:00:00 EDT 2021
Multiplexed immunofluorescence identifies high stromal CD68+PD-L1+ macrophages as a predictor of improved survival in triple negative breast cancer.
Scientific reports
Wang J,Browne L,Slapetova I,Shang F,Lee K,Lynch J,Beretov J,Whan R,Graham PH,Millar EKA
Published figure using CD8 alpha monoclonal antibody (Product # MA5-13473) in Immunohistochemistry
Wed Nov 03 00:00:00 EDT 2021
Increased infiltration of regulatory T cells in hepatocellular carcinoma of patients with hepatitis B virus pre-S2 mutant.
Scientific reports
Teng CF,Li TC,Wang T,Liao DC,Wen YH,Wu TH,Wang J,Wu HC,Shyu WC,Su IJ,Jeng LB
MA5-13473 was used in Immunohistochemistry-immunofluorescence to provide new insights into the pathogenesis of HBV pre-S2 mutant-induced HCC and suggest that therapeutics targeting Tregs may be a promising strategy for treating pre-S2 mutant-positive high-risk patient population.
Wed Jan 13 00:00:00 EST 2021
Increased infiltration of regulatory T cells in hepatocellular carcinoma of patients with hepatitis B virus pre-S2 mutant.
Scientific reports
Teng CF,Li TC,Wang T,Liao DC,Wen YH,Wu TH,Wang J,Wu HC,Shyu WC,Su IJ,Jeng LB
MA5-13473 was used in Immunohistochemistry-immunofluorescence to provide new insights into the pathogenesis of HBV pre-S2 mutant-induced HCC and suggest that therapeutics targeting Tregs may be a promising strategy for treating pre-S2 mutant-positive high-risk patient population.
Wed Jan 13 00:00:00 EST 2021
Therapeutic efficacy of dendritic cell vaccine combined with programmed death 1 inhibitor for hepatocellular carcinoma.
Journal of gastroenterology and hepatology
Teng CF,Wang T,Shih FY,Shyu WC,Jeng LB
MA5-13473 was used in Flow Cytometry, Immunohistochemistry (Paraffin) to suggest that a combination treatment with DC vaccine and PD-1 inhibitor may be a promising therapeutic strategy for HCC.
Thu Jul 01 00:00:00 EDT 2021
Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.
Immunity
Werneburg S,Jung J,Kunjamma RB,Ha SK,Luciano NJ,Willis CM,Gao G,Biscola NP,Havton LA,Crocker SJ,Popko B,Reich DS,Schafer DP
MA5-13473 was used in Immunohistochemistry to indicate that microglia eliminate synapses through the alternative complement cascade in demyelinating disease and identify a strategy to prevent synapse loss that may be broadly applicable to other neurodegenerative diseases.
Tue Jan 14 00:00:00 EST 2020
Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma.
International journal of cancer
Lundgren S,Elebro J,Heby M,Nodin B,Leandersson K,Micke P,Jirström K,Mezheyeuski A
MA5-13473 was used in Immunohistochemistry to demonstrate that the composition and clinical impact of immune infiltrates in periampullary adenocarcinoma differ by morphological type as well as localization.
Mon Jun 15 00:00:00 EDT 2020
Combination therapy with dendritic cell vaccine and programmed death ligand 1 immune checkpoint inhibitor for hepatocellular carcinoma in an orthotopic mouse model.
Therapeutic advances in medical oncology
Teng CF,Wang T,Wu TH,Lin JH,Shih FY,Shyu WC,Jeng LB
MA5-13473 was used in Immunohistochemistry-immunofluorescence to suggest that combination therapy with DC vaccine and PD-L1 inhibitor might have great promise as a novel treatment strategy for HCC.
Fri Apr 15 00:00:00 EDT 2022
Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma.
Nature communications
Mitra A,Andrews MC,Roh W,De Macedo MP,Hudgens CW,Carapeto F,Singh S,Reuben A,Wang F,Mao X,Song X,Wani K,Tippen S,Ng KS,Schalck A,Sakellariou-Thompson DA,Chen E,Reddy SM,Spencer CN,Wiesnoski D,Little LD,Gumbs C,Cooper ZA,Burton EM,Hwu P,Davies MA,Zhang J,Bernatchez C,Navin N,Sharma P,Allison JP,Wargo JA,Yee C,Tetzlaff MT,Hwu WJ,Lazar AJ,Futreal PA
MA5-13473 was used in Immunohistochemistry to highlight the links between marked levels of genomic and immune heterogeneity within the physical space of a tumor, with implications for biomarker evaluation and immunotherapy response.
Wed Apr 15 00:00:00 EDT 2020
Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma.
Nature communications
Mitra A,Andrews MC,Roh W,De Macedo MP,Hudgens CW,Carapeto F,Singh S,Reuben A,Wang F,Mao X,Song X,Wani K,Tippen S,Ng KS,Schalck A,Sakellariou-Thompson DA,Chen E,Reddy SM,Spencer CN,Wiesnoski D,Little LD,Gumbs C,Cooper ZA,Burton EM,Hwu P,Davies MA,Zhang J,Bernatchez C,Navin N,Sharma P,Allison JP,Wargo JA,Yee C,Tetzlaff MT,Hwu WJ,Lazar AJ,Futreal PA
MA5-13473 was used in Immunohistochemistry to highlight the links between marked levels of genomic and immune heterogeneity within the physical space of a tumor, with implications for biomarker evaluation and immunotherapy response.
Wed Apr 15 00:00:00 EDT 2020
UV radiation recruits CD4+GATA3+ and CD8+GATA3+ T cells while altering the lipid microenvironment following inflammatory resolution in human skin in vivo.
Clinical & translational immunology
Hawkshaw NJ,Pilkington SM,Murphy SA,Al-Gazaq N,Farrar MD,Watson RE,Nicolaou A,Rhodes LE
MA5-13473 was used in Immunohistochemistry to examine the skin immune and lipid profile over time following ultraviolet radiation inflammation.
Wed Apr 01 00:00:00 EDT 2020
Prognostic Interactions between FAP+ Fibroblasts and CD8a+ T Cells in Colon Cancer.
Cancers
Herrera M,Mezheyeuski A,Villabona L,Corvigno S,Strell C,Klein C,Hölzlwimmer G,Glimelius B,Masucci G,Sjöblom T,Östman A
MA5-13473 was used in Immunohistochemistry to present findings relevant for the ongoing efforts to improve the prognostic performance of CD8-related markers and should be followed by additional validation studies.
Tue Nov 03 00:00:00 EST 2020
PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma.
Nature communications
Liu XD,Kong W,Peterson CB,McGrail DJ,Hoang A,Zhang X,Lam T,Pilie PG,Zhu H,Beckermann KE,Haake SM,Isgandrova S,Martinez-Moczygemba M,Sahni N,Tannir NM,Lin SY,Rathmell WK,Jonasch E
MA5-13473 was used in Immunohistochemistry to investigate if PBRM1/Pbrm1 deficiency can reduce the binding of brahma-related gene 1 (BRG1) to the IFNγ receptor 2 (Ifngr2) promoter, thus decreasing STAT1 phosphorylation and the subsequent expression of IFNγ target genes.
Fri May 01 00:00:00 EDT 2020
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
Cancer cell
Cassetta L,Fragkogianni S,Sims AH,Swierczak A,Forrester LM,Zhang H,Soong DYH,Cotechini T,Anur P,Lin EY,Fidanza A,Lopez-Yrigoyen M,Millar MR,Urman A,Ai Z,Spellman PT,Hwang ES,Dixon JM,Wiechmann L,Coussens LM,Smith HO,Pollard JW
MA5-13473 was used in Immunohistochemistry to show that monocyte subpopulation distribution and transcriptomes are significantly altered by the presence of endometrial and breast cancer.
Mon Apr 15 00:00:00 EDT 2019
Poor Response to Neoadjuvant Chemotherapy Correlates with Mast Cell Infiltration in Inflammatory Breast Cancer.
Cancer immunology research
Reddy SM,Reuben A,Barua S,Jiang H,Zhang S,Wang L,Gopalakrishnan V,Hudgens CW,Tetzlaff MT,Reuben JM,Tsujikawa T,Coussens LM,Wani K,He Y,Villareal L,Wood A,Rao A,Woodward WA,Ueno NT,Krishnamurthy S,Wargo JA,Mittendorf EA
MA5-13473 was used in Immunohistochemistry to highlight the strong association of mast cell infiltration with poor response to NAC, suggesting a mechanism of treatment resistance and a potential therapeutic target in IBC.
Sat Jun 01 00:00:00 EDT 2019
RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade.
Molecular therapy : the journal of the American Society of Gene Therapy
Ganesh S,Shui X,Craig KP,Park J,Wang W,Brown BD,Abrams MT
MA5-13473 was used in Immunohistochemistry to support RNAi-mediated Β-catenin inhibition as an effective strategy to increase response rates to cancer immunotherapy.
Wed Nov 07 00:00:00 EST 2018
Role of regulatory T cells and CD8+ T lymphocytes in the dissemination of circulating tumor cells in primary invasive breast cancer.
Oncology letters
Xue D,Xia T,Wang J,Chong M,Wang S,Zhang C
Sat Sep 01 00:00:00 EDT 2018
Role of regulatory T cells and CD8+ T lymphocytes in the dissemination of circulating tumor cells in primary invasive breast cancer.
Oncology letters
Xue D,Xia T,Wang J,Chong M,Wang S,Zhang C
Sat Sep 01 00:00:00 EDT 2018
Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer.
NPJ breast cancer
Stover DG,Gil Del Alcazar CR,Brock J,Guo H,Overmoyer B,Balko J,Xu Q,Bardia A,Tolaney SM,Gelman R,Lloyd M,Wang Y,Xu Y,Michor F,Wang V,Winer EP,Polyak K,Lin NU
Thu Oct 01 00:00:00 EDT 2020
A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms.
Cancer informatics
Barua S,Solis L,Parra ER,Uraoka N,Jiang M,Wang H,Rodriguez-Canales J,Wistuba I,Maitra A,Sen S,Rao A
MA5-13473 was used in Immunohistochemistry-immunofluorescence to produce a model, using spatial cellular interactions in Intraductal papillary mucinous neoplasms to predict the transformation of low-grade IPMN cysts to high-grade cysts en route to pancreatic ductal adenocarcinoma.
Thu Sep 09 00:00:00 EDT 2021
Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ashizawa T,Iizuka A,Nonomura C,Kondou R,Maeda C,Miyata H,Sugino T,Mitsuya K,Hayashi N,Nakasu Y,Maruyama K,Yamaguchi K,Katano I,Ito M,Akiyama Y
MA513473 was used in immunohistochemistry to utilize humanized major histocompatibility class I- and class II-deficient NOG mice to assess the antitumor effect of an anti-programmed death-1 antibody
Sun Jan 01 00:00:00 EST 2017
Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues.
Scientific reports
Parra ER,Uraoka N,Jiang M,Cook P,Gibbons D,Forget MA,Bernatchez C,Haymaker C,Wistuba II,Rodriguez-Canales J
MA5-13473 was used in Immunohistochemistry to validate multiplex immunofluorescence panels to apply to formalin-fixed and paraffin-embedded tissues.
Tue Oct 17 00:00:00 EDT 2017
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.
NPJ genomic medicine
Reuben A,Spencer CN,Prieto PA,Gopalakrishnan V,Reddy SM,Miller JP,Mao X,De Macedo MP,Chen J,Song X,Jiang H,Chen PL,Beird HC,Garber HR,Roh W,Wani K,Chen E,Haymaker C,Forget MA,Little LD,Gumbs C,Thornton RL,Hudgens CW,Chen WS,Austin-Breneman J,Sloane RS,Nezi L,Cogdill AP,Bernatchez C,Roszik J,Hwu P,Woodman SE,Chin L,Tawbi H,Davies MA,Gershenwald JE,Amaria RN,Glitza IC,Diab A,Patel SP,Hu J,Lee JE,Grimm EA,Tetzlaff MT,Lazar AJ,Wistuba II,Clise-Dwyer K,Carter BW,Zhang J,Futreal PA,Sharma P,Allison JP,Cooper ZA,Wargo JA
MA5-13473 was used in Immunohistochemistry on paraffin embedded tissues to yield insight into differential therapeutic responses to targeted therapy and immune checkpoint blockade in melanoma, and have key translational implications in the age of precision medicine.
Sat Jan 02 00:00:00 EST 2021
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.
NPJ genomic medicine
Reuben A,Spencer CN,Prieto PA,Gopalakrishnan V,Reddy SM,Miller JP,Mao X,De Macedo MP,Chen J,Song X,Jiang H,Chen PL,Beird HC,Garber HR,Roh W,Wani K,Chen E,Haymaker C,Forget MA,Little LD,Gumbs C,Thornton RL,Hudgens CW,Chen WS,Austin-Breneman J,Sloane RS,Nezi L,Cogdill AP,Bernatchez C,Roszik J,Hwu P,Woodman SE,Chin L,Tawbi H,Davies MA,Gershenwald JE,Amaria RN,Glitza IC,Diab A,Patel SP,Hu J,Lee JE,Grimm EA,Tetzlaff MT,Lazar AJ,Wistuba II,Clise-Dwyer K,Carter BW,Zhang J,Futreal PA,Sharma P,Allison JP,Cooper ZA,Wargo JA
MA5-13473 was used in Immunohistochemistry on paraffin embedded tissues to yield insight into differential therapeutic responses to targeted therapy and immune checkpoint blockade in melanoma, and have key translational implications in the age of precision medicine.
Sat Jan 02 00:00:00 EST 2021
Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Cancer discovery
Chen PL,Roh W,Reuben A,Cooper ZA,Spencer CN,Prieto PA,Miller JP,Bassett RL,Gopalakrishnan V,Wani K,De Macedo MP,Austin-Breneman JL,Jiang H,Chang Q,Reddy SM,Chen WS,Tetzlaff MT,Broaddus RJ,Davies MA,Gershenwald JE,Haydu L,Lazar AJ,Patel SP,Hwu P,Hwu WJ,Diab A,Glitza IC,Woodman SE,Vence LM,Wistuba II,Amaria RN,Kwong LN,Prieto V,Davis RE,Ma W,Overwijk WW,Sharpe AH,Hu J,Futreal PA,Blando J,Sharma P,Allison JP,Chin L,Wargo JA
MA5-13473 was used in immunohistochemistry - paraffin section to gain insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade by analysis of immune signatures in longitudinal tumor samples
Mon Aug 01 00:00:00 EDT 2016
Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Cancer discovery
Chen PL,Roh W,Reuben A,Cooper ZA,Spencer CN,Prieto PA,Miller JP,Bassett RL,Gopalakrishnan V,Wani K,De Macedo MP,Austin-Breneman JL,Jiang H,Chang Q,Reddy SM,Chen WS,Tetzlaff MT,Broaddus RJ,Davies MA,Gershenwald JE,Haydu L,Lazar AJ,Patel SP,Hwu P,Hwu WJ,Diab A,Glitza IC,Woodman SE,Vence LM,Wistuba II,Amaria RN,Kwong LN,Prieto V,Davis RE,Ma W,Overwijk WW,Sharpe AH,Hu J,Futreal PA,Blando J,Sharma P,Allison JP,Chin L,Wargo JA
MA5-13473 was used in immunohistochemistry - paraffin section to gain insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade by analysis of immune signatures in longitudinal tumor samples
Mon Aug 01 00:00:00 EDT 2016
APOBEC3G Expression Correlates with T-Cell Infiltration and Improved Clinical Outcomes in High-grade Serous Ovarian Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Leonard B,Starrett GJ,Maurer MJ,Oberg AL,Van Bockstal M,Van Dorpe J,De Wever O,Helleman J,Sieuwerts AM,Berns EM,Martens JW,Anderson BD,Brown WL,Kalli KR,Kaufmann SH,Harris RS
MA5-13473 was used in Immunohistochemistry-immunofluorescence to investigate whether correlations exist between APOBEC3 expression and T-cell infiltration in high-grade serous ovarian cancer, and assess the prognostic value.
Thu Sep 15 00:00:00 EDT 2016
STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.
Cancer research
Koyama S,Akbay EA,Li YY,Aref AR,Skoulidis F,Herter-Sprie GS,Buczkowski KA,Liu Y,Awad MM,Denning WL,Diao L,Wang J,Parra-Cuentas ER,Wistuba II,Soucheray M,Thai T,Asahina H,Kitajima S,Altabef A,Cavanaugh JD,Rhee K,Gao P,Zhang H,Fecci PE,Shimamura T,Hellmann MD,Heymach JV,Hodi FS,Freeman GJ,Barbie DA,Dranoff G,Hammerman PS,Wong KK
MA5-13473 was used in Immunohistochemistry to investigate the consequences of STK11/LKB1 loss on the immune microenvironment in a mouse model of KRAS-driven non-small cell lung cancer.
Tue Mar 01 00:00:00 EST 2016
Smoking is an independent association of squamous metaplasia in Chinese nasal polyps.
International forum of allergy & rhinology
Gao T,Ng CL,Li C,Li YY,Duan C,Shen L,Jiao YF,Liu M,Wang de Y
MA5-13473 was used in immunohistochemistry - paraffin section to characterize Chinese nasal polyp
Fri Jan 01 00:00:00 EST 2016
Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium.
American journal of reproductive immunology (New York, N.Y. : 1989)
Shanmugasundaram U,Hilton JF,Critchfield JW,Greenblatt RM,Giudice LC,Averbach S,Seidman D,Shacklett BL,Smith-McCune K
MA5-13473 was used in Immunohistochemistry to study the impact of the levonorgestrel-releasing intrauterine device on immune parameters of the upper female reproductive tract.
Mon Aug 01 00:00:00 EDT 2016
Histopathological features of sinonasal inverted papillomas in chinese patients.
The Laryngoscope
Zhao L,Li CW,Jin P,Ng CL,Lin ZB,Li YY,Li TY,Petersson BF,Shi L,Wang de Y
MA5-13473 was used in immunohistochemistry - paraffin section to examine the histopathological patterns and their associations with clinical characteristics in Chinese patients with nasal inverted papilloma
Fri Apr 01 00:00:00 EDT 2016
A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism.
Proceedings of the National Academy of Sciences of the United States of America
Li G,Nguyen CC,Ryckman BJ,Britt WJ,Kamil JP
MA5-13473 was used in immunoprecipitation to investigate the assembly of glycoprotein complexes by human cytomegalovirus.
Tue Apr 07 00:00:00 EDT 2015
The differential diagnosis of CD8-positive ("type D") lymphomatoid papulosis.
Journal of cutaneous pathology
McQuitty E,Curry JL,Tetzlaff MT,Prieto VG,Duvic M,Torres-Cabala C
MA5-13473 was used in immunohistochemistry to study histopathological features that may aid in the differential diagnosis of CD8+ lymphomatoid papulosus
Sat Feb 01 00:00:00 EST 2014
Analysis of FoxP3+ T-regulatory cells and CD8+ T-cells in ovarian carcinoma: location and tumor infiltration patterns are key prognostic markers.
PloS one
Hermans C,Anz D,Engel J,Kirchner T,Endres S,Mayr D
MA5-13473 was used in immunohistochemistry - paraffin section to characterize location and tumor infiltration patterns as key prognostic factors when analyzing CD8+ T-cells and FoxP3+ T-regulatory cells in ovarian carcinoma
Thu Feb 04 00:00:00 EST 2016
Viral acute lower respiratory infections impair CD8+ T cells through PD-1.
The Journal of clinical investigation
Erickson JJ,Gilchuk P,Hastings AK,Tollefson SJ,Johnson M,Downing MB,Boyd KL,Johnson JE,Kim AS,Joyce S,Williams JV
MA5-13473 was used in immunohistochemistry to study the role of PD-1 in the mechanism by which viral acute lower respiratory tract infections impair CD8+ T-cell function
Wed Aug 01 00:00:00 EDT 2012
Leukocyte composition of human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America
Ruffell B,Au A,Rugo HS,Esserman LJ,Hwang ES,Coussens LM
MA5-13473 was used in immunohistochemistry to examine tumor and nonadjacent normal breast tissue from women with breast cancer, who either had or had not received neoadjuvant chemotherapy before surgery
Tue Feb 21 00:00:00 EST 2012
In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950)
Chang A,Henderson SG,Brandt D,Liu N,Guttikonda R,Hsieh C,Kaverina N,Utset TO,Meehan SM,Quigg RJ,Meffre E,Clark MR
MA5-13473 was used in immunohistochemistry to study the involvement of B cell-mediated immune responses in the pathogenesis of lupus tubulointerstitial inflammation
Tue Feb 01 00:00:00 EST 2011
Memory B-cell aggregates in skin biopsy are diagnostic for primary Sjögren's syndrome.
Journal of autoimmunity
Roguedas AM,Pers JO,Lemasson G,Devauchelle V,Tobón GJ,Saraux A,Misery L,Youinou P
MA5-13473 was used in immunohistochemistry to investigate the use of B-cell skin infiltrates in the diagnosis of Sjogren's syndrome.
Mon Nov 01 00:00:00 EDT 2010
Tracking the rejection and survival of mouse ovarian iso- and allografts in vivo with bioluminescent imaging.
Reproduction (Cambridge, England)
Chen CH,Yeh YC,Wu GJ,Huang YH,Lai WF,Liu JY,Tzeng CR
MA5-13473 was used in immunohistochemistry to study the use of bioluminescent imaging in transgenic mice to monitor the survival and rejection of ovarian isografts and allografts
Thu Jul 01 00:00:00 EDT 2010
Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy--a case report.
Journal of translational medicine
Milani V,Stangl S,Issels R,Gehrmann M,Wagner B,Hube K,Mayr D,Hiddemann W,Molls M,Multhoff G
MA5-13473 was used in immunohistochemistry to report on a colon cancer patient treated with repeated infusions of ex vivo TKD/IL-2-activated NK cells
Tue Jun 23 00:00:00 EDT 2009
Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice.
Journal of immunology (Baltimore, Md. : 1950)
Voehringer D,Liang HE,Locksley RM
MA5-13473 was used in Flow Cytometry to demonstrate that T(ML) cells are not sufficient to mediate an effective immune response in constitutively T cell-depleted mice.
Tue Apr 01 00:00:00 EDT 2008
Local immune alterations in oral mucosa of the edentulous patients; possible cause of teeth loss?
Romanian journal of internal medicine = Revue roumaine de medecine interne
Zurac S,Girtan M,Lavric L,Petsakos G,Stăniceanu F,Bastian A,Andrei R,Popp C,Laba E
MA5-13473 was used in immunohistochemistry to investigate immune cells of oral mucosa derived from edentulous patients
Tue May 12 00:00:00 EDT 2009
CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma.
Proceedings of the National Academy of Sciences of the United States of America
Sharma P,Shen Y,Wen S,Yamada S,Jungbluth AA,Gnjatic S,Bajorin DF,Reuter VE,Herr H,Old LJ,Sato E
MA5-13473 was used in immunohistochemistry to study the prognostic value of CD8 tumor-infiltrating lymphocytes in muscle-invasive urothelial carcinoma
Tue Mar 06 00:00:00 EST 2007
BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjögren's syndrome.
Arthritis and rheumatism
Pers JO,Devauchelle V,Daridon C,Bendaoud B,Le Berre R,Bordron A,Hutin P,Renaudineau Y,Dueymes M,Loisel S,Berthou C,Saraux A,Youinou P
MA5-13473 was used in immunohistochemistry to investigate the mechanism for the repopulation of B lymphocytes after rituximab treatment
Tue May 01 00:00:00 EDT 2007
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer.
Proceedings of the National Academy of Sciences of the United States of America
Sato E,Olson SH,Ahn J,Bundy B,Nishikawa H,Qian F,Jungbluth AA,Frosina D,Gnjatic S,Ambrosone C,Kepner J,Odunsi T,Ritter G,Lele S,Chen YT,Ohtani H,Old LJ,Odunsi K
MA5-13473 was used in immunohistochemistry to study the prognostic value of intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio in ovarian cancer
Tue Dec 20 00:00:00 EST 2005
Immunohistochemical analysis of orbital connective tissue specimens of patients with active Graves ophthalmopathy.
Current eye research
Avunduk AM,Avunduk MC,Pazarli H,Oguz V,Varnell ED,Kaufman HE,Aksoy F
MA5-13473 was used in immunohistochemistry to study the cells infiltrating orbital connective tissue in patients with active Graves opthalmopathy
Mon Aug 01 00:00:00 EDT 2005
Etanercept treatment in the endotoxin-induced uveitis of rats.
Experimental eye research
Avunduk MC,Avunduk AM,Oztekin E,Baltaci AK,Ozyazgan Y,Mogolkoc R
MA5-13473 was used in immunohistochemistry to investigate the therapeutic effect of etanercept on endotoxin-induced uveitis in rats
Wed Sep 01 00:00:00 EDT 2004
