Product References
Anti-Schmallenberg Virus Activities of Type I/III Interferons-Induced Mx1 GTPases from Different Mammalian Species.
Viruses
Bayrou C,Van Laere AS,Dam Van P,Moula N,Garigliany MM,Desmecht D
MA5-15253 was used in Western Blotting to conclude that Mx1 has a strong, dose-dependent anti-Schmallenberg activity in these four mammalian species.
Tue Apr 25 00:00:00 EDT 2023
Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nature communications
Fujita J,Amesaka H,Yoshizawa T,Hibino K,Kamimura N,Kuroda N,Konishi T,Kato Y,Hara M,Inoue T,Namba K,Tanaka SI,Matsumura H
MA5-15253 was used in Immunocytochemistry to highlight the physiological roles of the conformational changes of FtsZ in treadmilling that regulate cell division.
Mon Jul 10 00:00:00 EDT 2023
EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMO.
Frontiers in cell and developmental biology
Barbeito P,Martin-Morales R,Palencia-Campos A,Cerrolaza J,Rivas-Santos C,Gallego-Colastra L,Caparros-Martin JA,Martin-Bravo C,Martin-Hurtado A,Sánchez-Bellver L,Marfany G,Ruiz-Perez VL,Garcia-Gonzalo FR
MA5-15253 was used in Western Blotting to find that EvC zone targeting of EVC-EVC2 depends on two separate EFCAB7-binding motifs within EVC2's Weyers-deleted peptide.
Tue Aug 15 00:00:00 EDT 2023
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.
Acta neuropathologica
Bauer CS,Cohen RN,Sironi F,Livesey MR,Gillingwater TH,Highley JR,Fillingham DJ,Coldicott I,Smith EF,Gibson YB,Webster CP,Grierson AJ,Bendotti C,De Vos KJ
MA5-15253 was used in Western Blotting to show that C9orf72 plays a cell-autonomous role in the regulation of neurotransmission at excitatory synapses by interaction with synapsin and modulation of synaptic vesicle pools, and identify a novel role for C9orf72 haploinsufficiency in synaptic dysfunction in C9ALS/FTD.
Thu Sep 01 00:00:00 EDT 2022
The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.
The Journal of cell biology
Stormo AED,Shavarebi F,FitzGibbon M,Earley EM,Ahrendt H,Lum LS,Verschueren E,Swaney DL,Skibinski G,Ravisankar A,van Haren J,Davis EJ,Johnson JR,Von Dollen J,Balen C,Porath J,Crosio C,Mirescu C,Iaccarino C,Dauer WT,Nichols RJ,Wittmann T,Cox TC,Finkbeiner S,Krogan NJ,Oakes SA,Hiniker A
MA5-15253 was used in Immunoprecipitation to suggest that TRIM1 is a critical regulator of LRRK2, controlling its degradation, localization, binding partners, kinase activity, and cytotoxicity.
Mon Apr 04 00:00:00 EDT 2022
ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16INK4a levels.
Nature cell biology
Hao X,Shiromoto Y,Sakurai M,Towers M,Zhang Q,Wu S,Havas A,Wang L,Berger S,Adams PD,Tian B,Nishikura K,Kossenkov AV,Liu P,Zhang R
MA5-15253 was used in Western Blotting to reveal an RNA-editing-independent role for ADAR1 in the regulation of senescence by post-transcriptionally controlling p16INK4a expression.
Mon Aug 01 00:00:00 EDT 2022
A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation.
Cell reports
Carrasco J,Mateos F,Hilgers V
MA5-15253 was used in Western Blotting to demonstrate the essential role of robust cellular strategies to maintain ELAV activity and intact neuronal signatures in neurogenesis and neuronal function.
Tue Oct 25 00:00:00 EDT 2022
Dominant-Negative Form of SIGIRR: SIGIRRΔE8 Promotes Tumor Growth Through Regulation of Metabolic Pathways.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Bodaszewska-Lubas M,Liao Y,Zegar A,Szelest O,Dobrucki J,Bulek K
MA5-15253 was used in Immunoprecipitation Western Blotting to find that SIGIRRΔE8 exerts a direct impact on cell metabolism through interaction with the adenosine triphosphate synthase in the colorectal cancer cells.
Thu Sep 01 00:00:00 EDT 2022
Dominant-Negative Form of SIGIRR: SIGIRRΔE8 Promotes Tumor Growth Through Regulation of Metabolic Pathways.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Bodaszewska-Lubas M,Liao Y,Zegar A,Szelest O,Dobrucki J,Bulek K
MA5-15253 was used in Immunoprecipitation Western Blotting to find that SIGIRRΔE8 exerts a direct impact on cell metabolism through interaction with the adenosine triphosphate synthase in the colorectal cancer cells.
Thu Sep 01 00:00:00 EDT 2022
A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry.
Viruses
Luu AP,Yao Z,Ramachandran S,Azzopardi SA,Miles LA,Schneider WM,Hoffmann HH,Bozzacco L,Garcia G,Gong D,Damoiseaux R,Tang H,Morizono K,Rudin CM,Sun R,Arumugaswami V,Poirier JT,MacDonald MR,Rice CM,Li MMH
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Wed Oct 20 00:00:00 EDT 2021
A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry.
Viruses
Luu AP,Yao Z,Ramachandran S,Azzopardi SA,Miles LA,Schneider WM,Hoffmann HH,Bozzacco L,Garcia G,Gong D,Damoiseaux R,Tang H,Morizono K,Rudin CM,Sun R,Arumugaswami V,Poirier JT,MacDonald MR,Rice CM,Li MMH
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Wed Oct 20 00:00:00 EDT 2021
The deubiquitinating enzyme USP7 regulates the transcription factor Nrf1 by modulating its stability in response to toxic metal exposure.
The Journal of biological chemistry
Han JJW,Ho DV,Kim HM,Lee JY,Jeon YS,Chan JY
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Tue Aug 31 00:00:00 EDT 2021
Sphingomyelin synthase-related protein generates diacylglycerol via the hydrolysis of glycerophospholipids in the absence of ceramide.
The Journal of biological chemistry
Murakami C,Sakane F
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Mon Aug 30 00:00:00 EDT 2021
Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus.
Biosafety and health
Wang Q,Luo Y,Shang W,Shi Z,Xiao G,Zhang L
MA5-15253 was used in Western Blotting to provide an overarching view into the host interactome of the SADS-CoV S protein and highlights potential targets for the development of therapeutics against SADS-CoV.
Tue Jun 01 00:00:00 EDT 2021
Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Nature communications
Teng KW,Tsai ST,Hattori T,Fedele C,Koide A,Yang C,Hou X,Zhang Y,Neel BG,O'Bryan JP,Koide S
MA5-15253 was used in Flow Cytometry to demonstrate the feasibility of selective targeting and degradation of KRAS mutants in the active state with noncovalent reagents and provide a starting point for designing noncovalent therapeutics against oncogenic RAS mutants.
Tue May 11 00:00:00 EDT 2021
Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro.
Frontiers in pharmacology
Fred SM,Kuivanen S,Ugurlu H,Casarotto PC,Levanov L,Saksela K,Vapalahti O,Castrén E
MA5-15253 was used in Western Blot to test currently available antidepressant and antipsychotic drugs on SARS-CoV-2 in cell culture models, expanding these studies to more recently emerged viral varients.
Sun Nov 05 00:00:00 EDT 2023
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Viruses
Wang Q,Xin Q,Shang W,Wan W,Xiao G,Zhang LK
MA5-15253 was used in Western Blot to explore the interactions between arenaviruses and STAT3, which may help us to better understand the molecular and cell biology of arenaviruses.
Tue May 25 00:00:00 EDT 2021
Small-molecule-induced polymerization triggers degradation of BCL6.
Nature
Słabicki M,Yoon H,Koeppel J,Nitsch L,Roy Burman SS,Di Genua C,Donovan KA,Sperling AS,Hunkeler M,Tsai JM,Sharma R,Guirguis A,Zou C,Chudasama P,Gasser JA,Miller PG,Scholl C,Fröhling S,Nowak RP,Fischer ES,Ebert BL
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Immunocytochemistry
Tue Dec 01 00:00:00 EST 2020
KEAP1/NFE2L2 Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition.
Cancer discovery
Binkley MS,Jeon YJ,Nesselbush M,Moding EJ,Nabet BY,Almanza D,Kunder C,Stehr H,Yoo CH,Rhee S,Xiang M,Chabon JJ,Hamilton E,Kurtz DM,Gojenola L,Owen SG,Ko RB,Shin JH,Maxim PG,Lui NS,Backhus LM,Berry MF,Shrager JB,Ramchandran KJ,Padda SK,Das M,Neal JW,Wakelee HA,Alizadeh AA,Loo BW,Diehn M
MA5-15253 was used in Western Blot to show that mutations in KEAP1 and NFE2L2 predict for LR after radiotherapy but not surgery in patients with NSCLC.
Tue Dec 01 00:00:00 EST 2020
PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.
The EMBO journal
Yang XD,Li W,Zhang S,Wu D,Jiang X,Tan R,Niu X,Wang Q,Wu X,Liu Z,Chen LF,Qin J,Su B
MA5-15253 was used in Western Blotting to show that NLRP3 inflammasome activation is suppressed by a centrosomal protein Spata2.
Wed Jan 15 00:00:00 EST 2020
Cdk1 Phosphorylation of the Dam1 Complex Strengthens Kinetochore-Microtubule Attachments.
Current biology : CB
Gutierrez A,Kim JO,Umbreit NT,Asbury CL,Davis TN,Miller MP,Biggins S
MA5-15253 was used in Immunoprecipitation to show Cdk1, the major mitotic kinase that drives the cell cycle, enhances kinetochore-microtubule attachment strength by increasing the residence time of Dam1c via Ask1.
Mon Nov 16 00:00:00 EST 2020
Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance.
Breast cancer research : BCR
Li L,Lin L,Veeraraghavan J,Hu Y,Wang X,Lee S,Tan Y,Schiff R,Wang XS
MA5-15253 was used in Immunoprecipitation to investigate the functional role of ESR1 in endocrine resistance has not been studied in vivo, and the engaged mechanism and therapeutic relevance.
Sat Aug 08 00:00:00 EDT 2020
Fumarate and oxidative stress synergize to promote stability of C/EBP homologous protein in the adipocyte.
Free radical biology & medicine
Manuel AM,Walla MD,Dorn MT,Tanis RM,Piroli GG,Frizzell N
MA5-15253 was used in Western Blotting to demonstrate that physiological increases in the metabolite fumarate during high glucose exposure contributes to the presence of oxidative stress and sustained CHOP levels in the adipocyte during diabetes.
Thu Feb 20 00:00:00 EST 2020
Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin.
The Journal of investigative dermatology
Crawford M,Leclerc V,Barr K,Dagnino L
MA5-15253 was used in Immunocytochemistry-immunoflourescence to report that targeted inactivation of the integrin-linked kinase gene in first wave melanoblasts causes defects in the ability of these cells to form long pseudopods, to migrate, and to proliferate in vivo.
Sat Feb 01 00:00:00 EST 2020
Defining the proteolytic landscape during enterovirus infection.
PLoS pathogens
Saeed M,Kapell S,Hertz NT,Wu X,Bell K,Ashbrook AW,Mark MT,Zebroski HA,Neal ML,Flodström-Tullberg M,MacDonald MR,Aitchison JD,Molina H,Rice CM
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Tue Sep 01 00:00:00 EDT 2020
A novel NanoBiT-based assay monitors the interaction between lipoprotein lipase and GPIHBP1 in real time.
Journal of lipid research
Shetty SK,Walzem RL,Davies BSJ
MA5-15253 was used in Western Blotting to modify the NanoLuc® Binary Technology split-luciferase system to develop a novel assay that monitors the binding of LPL to GPIHBP1 on endothelial cells in real time.
Wed Apr 01 00:00:00 EDT 2020
GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Parenté A,Boukredine A,Baraige F,Duprat N,Gondran-Tellier V,Magnol L,Blanquet V
MA5-15253 was used in Western Blotting to highlight the gene expression regulatory network of TGF-β members and their inhibitors in muscle.
Sun Mar 01 00:00:00 EST 2020
Growth-Dependent Activation of Protein Kinases Suggests a Mechanism for Measuring Cell Growth.
Genetics
Jasani A,Huynh T,Kellogg DR
MA5-15253 was used in Western Blot to suggest that signaling lipids delivered to the growing bud generate a growth-dependent signal that could be used to measure bud growth.
Wed Jul 01 00:00:00 EDT 2020
Conserved Ark1-related kinases function in a TORC2 signaling network.
Molecular biology of the cell
Alcaide-Gavilán M,Lucena R,Banuelos S,Kellogg DR
MA5-15253 was used in Western Blotting to search for new components of the TORC2 network identified a pair of redundant kinase paralogues called Ark1 and Prk1.
Sat Aug 15 00:00:00 EDT 2020
Conserved Ark1-related kinases function in a TORC2 signaling network.
Molecular biology of the cell
Alcaide-Gavilán M,Lucena R,Banuelos S,Kellogg DR
MA5-15253 was used in Western Blotting to search for new components of the TORC2 network identified a pair of redundant kinase paralogues called Ark1 and Prk1.
Sat Aug 15 00:00:00 EDT 2020
NonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells.
Frontiers in immunology
Lee K,Jang SH,Tian H,Kim SJ
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Mon Apr 26 00:00:00 EDT 2021
Diacylglycerol kinase δ and sphingomyelin synthase-related protein functionally interact via their sterile α motif domains.
The Journal of biological chemistry
Murakami C,Hoshino F,Sakai H,Hayashi Y,Yamashita A,Sakane F
MA5-15253 was used in Immunoprecipitation to find that SMSr-SAMD, but not SMS1-SAMD, co-immunoprecipitates with DGKδ-SAMD.and determine the functional outcomes of the relationship between DGKδ and SMSr.
Fri Mar 06 00:00:00 EST 2020
Gangliosides and CD82 inhibit the motility of colon cancer by downregulating the phosphorylation of EGFR at different tyrosine sites and signaling pathways.
Molecular medicine reports
Huang X,Li Y,He X,Chen Y,Wei W,Yang X,Ma K
MA5-15253 was used in Western Blotting to investigate CD82 and EGFR in colon cancer.
Sun Nov 01 00:00:00 EDT 2020
The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth.
PLoS genetics
Alizzi RA,Xu D,Tenenbaum CM,Wang W,Gavis ER
MA5-15253 was used in Western Blot to show that the ELAV/Hu family RNA-binding protein Found in neurons (Fne) is required for space-filling dendrite growth to generate highly branched arbors of Drosophila larval class IV dendritic arborization neurons.
Tue Dec 01 00:00:00 EST 2020
β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice.
American journal of physiology. Endocrinology and metabolism
Huynh FK,Peterson BS,Anderson KA,Lin Z,Coakley AJ,Llaguno FMS,Nguyen TN,Campbell JE,Stephens SB,Newgard CB,Hirschey MD
MA5-15253 was used in Western Blotting to suggest that SIRT4 controls nutrient-stimulated insulin secretion during aging by acting on tissues external to the β-cell, which warrants further study.
Thu Oct 01 00:00:00 EDT 2020
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing.
Nucleic acids research
Haldeman JM,Conway AE,Arlotto ME,Slentz DH,Muoio DM,Becker TC,Newgard CB
MA5-15253 was used in Western Blotting to develop versatile cloning platforms for transgene expression and dCas9-based epigenome editing.
Thu Feb 28 00:00:00 EST 2019
Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt.
Journal of cell science
Gleason CE,Oses-Prieto JA,Li KH,Saha B,Situ G,Burlingame AL,Pearce D
MA5-15253 was used in Western Blotting to demonstrate that SGK1 activation occurs at a distinct subcellular compartment from that of Akt and suggests a mechanism for the selective activation of these functionally distinct mTORC2 targets through subcellular partitioning of mTORC2 activity.
Tue Apr 09 00:00:00 EDT 2019
A fast and tuneable auxin-inducible degron for depletion of target proteins in budding yeast.
Yeast (Chichester, England)
Mendoza-Ochoa GI,Barrass JD,Terlouw BR,Maudlin IE,de Lucas S,Sani E,Aslanzadeh V,Reid JAE,Beggs JD
MA5-15253 was used in Western Blotting to conclude that TIR1 protein is a rate-limiting factor for target protein depletion in yeast, and we provide new tools that allow tightly controlled, tuneable, and efficient depletion of essential proteins whereas minimising secondary effects.
Tue Jan 01 00:00:00 EST 2019
Syndecan-4 regulates extravillous trophoblast migration by coordinating protein kinase C activation.
Scientific reports
Jeyarajah MJ,Jaju Bhattad G,Kops BF,Renaud SJ
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Immunoprecipitation
Mon Jul 15 00:00:00 EDT 2019
Syndecan-4 regulates extravillous trophoblast migration by coordinating protein kinase C activation.
Scientific reports
Jeyarajah MJ,Jaju Bhattad G,Kops BF,Renaud SJ
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Immunoprecipitation
Mon Jul 15 00:00:00 EDT 2019
The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.
Cellular and molecular gastroenterology and hepatology
Franke FC,Müller J,Abal M,Medina ED,Nitsche U,Weidmann H,Chardonnet S,Ninio E,Janssen KP
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Immunocytochemistry
Mon Apr 29 00:00:00 EDT 2019
The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.
Cellular and molecular gastroenterology and hepatology
Franke FC,Müller J,Abal M,Medina ED,Nitsche U,Weidmann H,Chardonnet S,Ninio E,Janssen KP
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Immunocytochemistry
Mon Apr 29 00:00:00 EDT 2019
Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions.
eLife
Nobre LV,Nightingale K,Ravenhill BJ,Antrobus R,Soday L,Nichols J,Davies JA,Seirafian S,Wang EC,Davison AJ,Wilkinson GW,Stanton RJ,Huttlin EL,Weekes MP
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Immunoprecipitation
Tue Dec 24 00:00:00 EST 2019
Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions.
eLife
Nobre LV,Nightingale K,Ravenhill BJ,Antrobus R,Soday L,Nichols J,Davies JA,Seirafian S,Wang EC,Davison AJ,Wilkinson GW,Stanton RJ,Huttlin EL,Weekes MP
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Immunoprecipitation
Tue Dec 24 00:00:00 EST 2019
The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.
Nature immunology
Castro W,Chelbi ST,Niogret C,Ramon-Barros C,Welten SPM,Osterheld K,Wang H,Rota G,Morgado L,Vivier E,Raeber ME,Boyman O,Delorenzi M,Barras D,Ho PC,Oxenius A,Guarda G
MA5-15253 was used in Western Blotting to show metabolism and homeostasis of natural killer cells can be regulated by transcription factor Rfx7.
Wed Aug 01 00:00:00 EDT 2018
The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.
Nature immunology
Castro W,Chelbi ST,Niogret C,Ramon-Barros C,Welten SPM,Osterheld K,Wang H,Rota G,Morgado L,Vivier E,Raeber ME,Boyman O,Delorenzi M,Barras D,Ho PC,Oxenius A,Guarda G
MA5-15253 was used in Western Blotting to show metabolism and homeostasis of natural killer cells can be regulated by transcription factor Rfx7.
Wed Aug 01 00:00:00 EDT 2018
Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-Dependent Protein Degradation.
Journal of virology
Westrich JA,Warren CJ,Klausner MJ,Guo K,Liu CW,Santiago ML,Pyeon D
MA5-15253 was used in Western Blotting to demonstrate that E7 stabilizes the APOBEC3A protein in human keratinocytes by inhibiting ubiquitin-dependent protein degradation in a cullin-dependent manner.
Sun Apr 01 00:00:00 EDT 2018
Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.
Structure (London, England : 1993)
Rothé B,Leettola CN,Leal-Esteban L,Cascio D,Fortier S,Isenschmid M,Bowie JU,Constam DB
MA5-15253 was used in Immunocytochemistry-immunoflourescence to conclude that the giant assemblies are shaped by SAM domains, their flanking sequences, and SAM-independent protein-protein and protein-mRNA interactions.
Tue Feb 06 00:00:00 EST 2018
VivosX, a disulfide crosslinking method to capture site-specific, protein-protein interactions in yeast and human cells.
eLife
Mohan C,Kim LM,Hollar N,Li T,Paulissen E,Leung CT,Luk E
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Thu Aug 09 00:00:00 EDT 2018
Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition.
Cell reports
Peterson BS,Campbell JE,Ilkayeva O,Grimsrud PA,Hirschey MD,Newgard CB
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Tue Jul 03 00:00:00 EDT 2018
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation.
Nature communications
Lin CC,Kitagawa M,Tang X,Hou MH,Wu J,Qu DC,Srinivas V,Liu X,Thompson JW,Mathey-Prevot B,Yao TP,Lee SH,Chi JT
MA5-15253 was used in Western Blotting to identify a novel mechanism that ensures faithful mitosis through acetylation, mediated by Coenzyme A synthase and acetyltransferase CBP.
Mon Mar 12 00:00:00 EDT 2018
A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size.
Developmental cell
Zhang P,Pei C,Wang X,Xiang J,Sun BF,Cheng Y,Qi X,Marchetti M,Xu JW,Sun YP,Edgar BA,Yuan Z
MA5-15253 was used in Western Blotting to demonstrate that interaction between Drosophila E2F1 and Sd disrupts Yki/Sd complex formation and thereby suppresses Yki target gene expression.
Mon Dec 04 00:00:00 EST 2017
TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP).
PLoS pathogens
Li MM,Lau Z,Cheung P,Aguilar EG,Schneider WM,Bozzacco L,Molina H,Buehler E,Takaoka A,Rice CM,Felsenfeld DP,MacDonald MR
MA515253 was used in western blot to investigate the antiviral mechanism of host factor and interferon-stimulated gene product, zinc-finger antiviral protein
Sun Jan 01 00:00:00 EST 2017
Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
Journal of molecular biology
Kükenshöner T,Schmit NE,Bouda E,Sha F,Pojer F,Koide A,Seeliger M,Koide S,Hantschel O
MA515253 was used in flow cytometry to target Src family kinase Src-homology 2 domains with high selectivity via the development of synthetic binding proteins, termed monobodies
Fri May 05 00:00:00 EDT 2017
In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β-dihydroexemestane.
Pharmacology research & perspectives
Peterson A,Xia Z,Chen G,Lazarus P
MA5-15253 was used in Western Blotting to show that functional polymorphisms in exemestane-metabolizing CYP450s contribute to variability in patient outcomes by mediating exemestane exposure and its active metabolite, 17Β-DHE.
Thu Jun 01 00:00:00 EDT 2017
Chemical-controlled Activation of Antiviral Myxovirus Resistance Protein 1.
The Journal of biological chemistry
Verhelst J,Van Hoecke L,Spitaels J,De Vlieger D,Kolpe A,Saelens X
MA515253 was used in immunoprecipitation to characterize a mouse antiviral myxovirus resistance protein 1 variant that only exerts antiviral activity in the presence of a small molecule drug
Fri Feb 10 00:00:00 EST 2017
RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling.
Scientific reports
Fu B,Zhao M,Wang L,Patil G,Smith JA,Juncadella IJ,Zuvela-Jelaska L,Dorf ME,Li S
MA5-15253 was used in Western Blotting to reveal that NXF1 selectively regulates TLR7-driven interferon regulatory factor 5 (IRF5) transcriptional activity, suggesting a new role for NXF1 in the IRF5 signalling pathway.
Fri Jun 02 00:00:00 EDT 2017
Sortilin limits EGFR signaling by promoting its internalization in lung cancer.
Nature communications
Al-Akhrass H,Naves T,Vincent F,Magnaudeix A,Durand K,Bertin F,Melloni B,Jauberteau MO,Lalloué F
MA5-15253 was used in Western Blotting to identify sortilin as a key regulator of epidermal growth factor receptor internalisation.
Mon Oct 30 00:00:00 EDT 2017
Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase.
Free radical biology & medicine
Han JW,Valdez JL,Ho DV,Lee CS,Kim HM,Wang X,Huang L,Chan JY
MA5-15253 was used in Immunoprecipitation to find that overexpression of HCF1 and OGT leads to increased Nrf1a protein stability.
Fri Sep 01 00:00:00 EDT 2017
Precise Editing of the Zebrafish Genome Made Simple and Efficient.
Developmental cell
Hoshijima K,Jurynec MJ,Grunwald DJ
MA5-15253 was used in Immunohistochemistry to significantly advance applicability of the zebrafish for studying normal biological processes and modeling diseases.
Mon Mar 21 00:00:00 EDT 2016
H295R expression of melanocortin 2 receptor accessory protein results in ACTH responsiveness.
Journal of molecular endocrinology
Nanba K,Chen AX,Turcu AF,Rainey WE
MA5-15253 was used in western blot to characterize ACTH responsiveness by H295R expression of melanocortin 2 receptor accessory protein
Mon Feb 01 00:00:00 EST 2016
Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4.
Biochemical and biophysical research communications
Enomoto S,Mitsui K,Kawamura T,Iwanari H,Daigo K,Horiuchi K,Minami T,Kodama T,Hamakubo T
MA5-15253 was used in western blot to characterize Robo4 and mediation of HUVEC migration and suppression of Slit2/Robo1
Fri Jan 22 00:00:00 EST 2016
Tead and AP1 Coordinate Transcription and Motility.
Cell reports
Liu X,Li H,Rajurkar M,Li Q,Cotton JL,Ou J,Zhu LJ,Goel HL,Mercurio AM,Park JS,Davis RJ,Mao J
MA5-15253 was used in immunoprecipitation and western blot investigate Tead4-mediated transcriptional networks in various types of cancer cells
Tue Feb 09 00:00:00 EST 2016
Unique nonstructural proteins of Pneumonia Virus of Mice (PVM) promote degradation of interferon (IFN) pathway components and IFN-stimulated gene proteins.
Scientific reports
Dhar J,Barik S
MA515253 was used in immunocytochemistry and immunoprecipitation to show that recombinant pneumonia virus of mice NS proteins degrades the members of the IFN pathway
Thu Dec 01 00:00:00 EST 2016
Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death.
Oncotarget
Tosello V,Saccomani V,Yu J,Bordin F,Amadori A,Piovan E
MA515253 was used in western blot to identify downstream targets/effectors involved in the pro-oncogenic activity of calcineurin in T-cell acute lymphoblastic leukemia
Tue Jul 19 00:00:00 EDT 2016
Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses.
Journal of virology
Verhelst J,Spitaels J,Nürnberger C,De Vlieger D,Ysenbaert T,Staeheli P,Fiers W,Saelens X
Published figure using V5 Tag monoclonal antibody (Product # MA5-15253) in Western Blot
Sun Nov 01 00:00:00 EDT 2015
Cyclophilin-D: a resident regulator of mitochondrial gene expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Radhakrishnan J,Bazarek S,Chandran B,Gazmuri RJ
MA5-15253 was used in ChIP assay and western blot to determine if cyclophilin-D regulates mitochondrial gene expression
Wed Jul 01 00:00:00 EDT 2015
E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program.
PloS one
Jiang X,Nevins JR,Shats I,Chi JT
MA5-15253 was used in western blot to identify the NF-YB transcription factor as a novel direct E2F1 target
Sun May 01 00:00:00 EDT 2016
Mutations in SPINT2 cause a syndromic form of congenital sodium diarrhea.
American journal of human genetics
Heinz-Erian P,Müller T,Krabichler B,Schranz M,Becker C,Rüschendorf F,Nürnberg P,Rossier B,Vujic M,Booth IW,Holmberg C,Wijmenga C,Grigelioniene G,Kneepkens CM,Rosipal S,Mistrik M,Kappler M,Michaud L,Dóczy LC,Siu VM,Krantz M,Zoller H,Utermann G,Janecke AR
MA5-15253 was used in western blot to identify the genetic basis of congenital sodium diarrhea
Sun Feb 01 00:00:00 EST 2009
