Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 3
1 µg/mL of MA5-45524 was sufficient for detection of Copper-transporting ATPase2 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.|Detects approximately 160kDa in rat brain membrane preparations.
This antibody was formerly sold as clone S62-29.
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease); Copper pump 2; Copper-transporting ATPase 2; PINA gene, promoter; pineal night-specific ATPase; RP11-327P2.1; RP11-327P2.3; toxic milk; Wilson disease-associated protein; Wilson disease-associated protein homolog; Wilson protein
Gene Aliases: Atp7a; ATP7B; Hts; PINA; PWD; tx; WC1; WD; WND
UniProt ID: (Human) P35670, (Mouse) Q64446
Entrez Gene ID: (Human) 540, (Rat) 24218, (Mouse) 11979
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support