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Invitrogen
Macrophages (Mature) Monoclonal Antibody (25F9)
Product Details
MA5-49061
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
25F9
Immunogen
The monoclonal antibody 25F9 recognizes a protein of 86 kD on the cell surface and within the cytoplasm of mature macrophages.
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
Protein G
Storage buffer
PBS with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
RRID
AB_3090344
Product Specific Information
The antibody is associated with fully differentiated tissue macrophages both in normal and in diseased tissues, independently of the presence or absence of inflammation. The antigen is absent on freshly isolated monocytes and other blood cells. After 6 to 7 days culture human monocytes become positive. Some melanoma and carcinoma cell lines are also positive. Furthermore the monoclonal antibody 25F9 cross reacts with a subpopulation of macrophages of rhesus monkey, pig alveolar macrophages and Kupffer cells.
Target Information
Macrophages are a type of white blood cell that plays a crucial role in the immune system. They are responsible for detecting, engulfing, and destroying foreign substances, such as bacteria and viruses, as well as dead cells and debris. Mature macrophages are found in various tissues throughout the body and are highly specialized to perform specific functions depending on their location. For example, alveolar macrophages are found in the lungs and are responsible for removing foreign particles that are inhaled, while Kupffer cells are found in the liver and are responsible for removing old or damaged red blood cells. Understanding the function and behavior of macrophages is crucial for developing new treatments for diseases such as cancer, autoimmune disorders, and infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Macrophages; Mature Macrophages
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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