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IL17RA Antibody (MA5-52438) in Flow
Flow cytometry analysis of Mouse IL17 expression on EL4 cells. Samples were incubated with IL17RA monoclonal antibody (Product # MA5-52438). The cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The dot plots were derived from gated of intact cells.
Product Details
MA5-52438
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
208
Immunogen
Recombinant Mouse IL17RA Protein (Thr22-Ala158)
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
100 µg/mL
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.03% ProClin 300
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD217; IL-17 receptor A; IL-17RA; Interleukin-17 receptor A; MGC10262
Gene Aliases: AW538159; Cdw217; Il17r; Il17ra; VDw217
UniProt ID: (Mouse) Q60943
Entrez Gene ID: (Mouse) 16172
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