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Product Details
20189-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAFB Fusion Protein Ag14102 (168-323 aa encoded by BC036689)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QASPPPSSA ASPAQQLPTS HPGPGPHATA SATAAGGNGS VEDRFSDDQL VSMSVRELNR HLRGFTKDEV IRLKQKRRTL KNRGYAQSCR YKRVQQKHHL ENEKTQLIQQ VEQLKQEVSR LARERDAYKV KCEKLANSGF REAGSTSDSP SSPEFFL (168-323 aa encoded by BC036689 )
Target Information
The protein encoded by this gene is a basic leucine zipper transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Kreisler; Kreisler (maf-related) leucine zipper protein; Kreisler maf-related leucine zipper homolog; Kreisler maf-related leucine zipper homolog (b-maf); Maf-B; MAFB/Kreisler basic region/leucine zipper transcription factor; MGC43127; Segmentation protein Kr; Transcription factor Maf-1; Transcription factor MafB; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B; V-maf musculoaponeurotic fibrosarcoma oncogene homolog B
Gene Aliases: b-maf; kr; Kreisler; KRML; Krml1; Maf1; MAFB; MCTO
UniProt ID: (Human) Q9Y5Q3, (Rat) P54842, (Mouse) P54841
Entrez Gene ID: (Human) 9935, (Rat) 54264, (Mouse) 16658
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
basic leucine zipper transcription factor
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
segment specification
nervous system development
sensory organ development
respiratory gaseous exchange
rhombomere 5 development
rhombomere 6 development
T cell differentiation in thymus
brain segmentation
inner ear morphogenesis
negative regulation of erythrocyte differentiation
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
thymus development
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
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