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Product Details
12771-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAFF Fusion Protein Ag3460 (1-164 aa encoded by BC015037)
Conjugate
Form
Liquid
Concentration
0.42 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSVDPLSSK ALKIKRELSE NTPHLSDEAL MGLSVRELNR HLRGLSAEEV TRLKQRRRTL KNRGYAASCR VKRVCQKEEL QKQKSELERE VDKLARENAA MRLELDALRG KCEALQGFAR SVAAARGPAT LVAPASVITI VKSTPGSGSG PAHGPDPAHG PASCS (1-164 aa encoded by BC015037)
Target Information
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Transcription factor MafF; U-Maf; v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F
Gene Aliases: hMafF; MAFF; U-MAF
UniProt ID: (Human) Q9ULX9, (Mouse) O54791
Entrez Gene ID: (Human) 23764, (Rat) 366960, (Mouse) 17133
in utero embryonic development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
parturition
blood coagulation
skeletal muscle cell differentiation
regulation of epidermal cell differentiation
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
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