Proteintech

MALT1 Polyclonal Antibody

MALT1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

MALT1 Antibody (11660-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells using 11660-1-AP (MALT1 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

MALT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

11660-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MALT1 Fusion Protein Ag2182 (125-450 aa encoded by BC030143)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: PGIKITVNP ESKAVLAGQF VKLCCRATGH PFVQYQWFKM NKEIPNGNTS ELIFNAVHVK DAGFYVCRVN NNFTFEFSQW SQLDVCDIPE SFQRSVDGVS ESKLQICVEP TSQKLMPGST LVLQCVAVGS PIPHYQWFKN ELPLTHETKK LYMVPYVDLE HQGTYWCHVY NDRDSQDSKK VEIIIDELNN LGHPDNKEQT TDQPLAKDKV ALLIGNMNYR EHPKLKAPLV DVYELTNLLR QLDFKVVSLL DLTEYEMRNA VDEFLLLLDK GVYGLLYYAG HGYENFGNSF MVPVDAPNPY RSENCLCVQN ILKLMQEKET GLNVFLL (125-450 aa encoded by BC030143 )

Target Information

MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

MALT1 promotes necroptosis in stroke rat brain via targeting the A20/RIPK3 pathway.

Archives of biochemistry and biophysics

Peng ZM,Zhang YY,Wei D,Zhang XJ,Liu B,Peng J,Luo XJ

Wed Feb 01 00:00:00 EST 2023

The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.

Molecular neurobiology

Zhang YY,Yang XY,Liu HQ,Zhang Z,Hu CP,Peng J,Luo XJ

Wed Mar 01 00:00:00 EST 2023

The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.

Molecular neurobiology

Zhang YY,Yang XY,Liu HQ,Zhang Z,Hu CP,Peng J,Luo XJ

Wed Mar 01 00:00:00 EST 2023

The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.

Molecular neurobiology

Zhang YY,Yang XY,Liu HQ,Zhang Z,Hu CP,Peng J,Luo XJ

Wed Mar 01 00:00:00 EST 2023

Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway.

European journal of pharmacology

Jiang YQ,Yang XY,Duan DQ,Zhang YY,Li NS,Tang LJ,Peng J,Luo XJ

Wed Jul 05 00:00:00 EDT 2023

Allicin suppressed Escherichia coli-induced urinary tract infections by a novel MALT1/NF-κB pathway.

Food & function

Chang Z,An L,He Z,Zhang Y,Li S,Lei M,Xu P,Lai Y,Jiang Z,Huang Y,Duan X,Wu W

Mon Mar 21 00:00:00 EDT 2022

Mucosa-Associated Lymphoid Tissue 1 Is an Oncogene Inducing Cell Proliferation, Invasion, and Tumor Growth via the Upregulation of NF-κB Activity in Human Prostate Carcinoma Cells.

Biomedicines

Tsui KH,Chang KS,Sung HC,Hsu SY,Lin YH,Hou CP,Yang PS,Chen CL,Feng TH,Juang HH

Wed Mar 03 00:00:00 EST 2021

Bioinformatics

Protein Aliases: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; malt1; MALT1 paracaspase; MALT1 protease; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; Paracaspase; paracaspase 1; paracaspase-1

View more View less

Gene Aliases: A630046N12; D430033E09Rik; IMD12; MALT1; MLT; MLT1; PCASP1

View more View less

UniProt ID: (Human) Q9UDY8, (Mouse) Q2TBA3

View more View less

Entrez Gene ID: (Human) 10892, (Rat) 307366, (Mouse) 240354

View more View less

Function(s)

protease binding cysteine-type endopeptidase activity ubiquitin-protein transferase activity signal transducer activity protein binding peptidase activity kinase activator activity protein self-association molecular_function hydrolase activity cysteine protease

Process(es)

B-1 B cell differentiation stimulatory C-type lectin receptor signaling pathway response to molecule of bacterial origin positive regulation of T cell cytokine production proteolysis defense response activation of NF-kappaB-inducing kinase activity response to fungus protein ubiquitination positive regulation of protein ubiquitination positive regulation of interleukin-2 production Fc-epsilon receptor signaling pathway T cell proliferation regulation of apoptotic process negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response T cell receptor signaling pathway regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity nuclear export protein oligomerization biological_process B cell activation apoptotic process I-kappaB kinase/NF-kappaB signaling

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

MALT1 Polyclonal Antibody

MALT1 Antibody (11660-1-AP) in ICC/IF

Product Details

11660-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!