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Product Details
PA5-142766
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-RPDNKEQTGQPLAK.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933412
Product Specific Information
Additional Information: This antibody is expected to recognize reported isoform 2 (XP_225927.5) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp434L132; malt-1; malt1; MALT1 paracaspase; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; Paracaspase
Gene Aliases: A630046N12; D430033E09Rik; Malt1
UniProt ID: (Mouse) Q2TBA3
Entrez Gene ID: (Rat) 307366, (Mouse) 240354
B-1 B cell differentiation
response to molecule of bacterial origin
positive regulation of T cell cytokine production
proteolysis
activation of NF-kappaB-inducing kinase activity
biological_process
response to fungus
protein ubiquitination
positive regulation of interleukin-2 production
T cell proliferation
B cell activation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
nuclear export
protein oligomerization
apoptotic process
I-kappaB kinase/NF-kappaB signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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