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Product Details
66225-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4D3F6
Immunogen
MALT1 Fusion Protein Ag20632 (125-450 aa encoded by BC030143)
Conjugate
Form
Liquid
Concentration
0.96 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PGIKITVNP ESKAVLAGQF VKLCCRATGH PFVQYQWFKM NKEIPNGNTS ELIFNAVHVK DAGFYVCRVN NNFTFEFSQW SQLDVCDIPE SFQRSVDGVS ESKLQICVEP TSQKLMPGST LVLQCVAVGS PIPHYQWFKN ELPLTHETKK LYMVPYVDLE HQGTYWCHVY NDRDSQDSKK VEIIIDELNN LGHPDNKEQT TDQPLAKDKV ALLIGNMNYR EHPKLKAPLV DVYELTNLLR QLDFKVVSLL DLTEYEMRNA VDEFLLLLDK GVYGLLYYAG HGYENFGNSF MVPVDAPNPY RSENCLCVQN ILKLMQEKET GLNVFLL (125-450 aa encoded by BC030143 )
Target Information
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; MALT1 protease; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase; paracaspase 1; paracaspase-1
Gene Aliases: IMD12; MALT1; MLT; MLT1; PCASP1
UniProt ID: (Human) Q9UDY8
Entrez Gene ID: (Human) 10892
B-1 B cell differentiation
stimulatory C-type lectin receptor signaling pathway
response to molecule of bacterial origin
positive regulation of T cell cytokine production
proteolysis
defense response
activation of NF-kappaB-inducing kinase activity
response to fungus
protein ubiquitination
positive regulation of protein ubiquitination
positive regulation of interleukin-2 production
Fc-epsilon receptor signaling pathway
T cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
nuclear export
protein oligomerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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