Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MGSQSSKAP RGDVTAEEAA GASPAKANGQ ENGHVKSNGD LSPKGEGESP PVNGTDEAAG ATGDAIEPAP TSQGAEAKGE VPPKETPKKK KKFSFKKPFK LSGLSFKRNR KEGGGDSSAS SPTEEEQEQG EIGACSDEGT AQEGKAAATP ESQEPQAKGA EASAASEEEA GPQATEPSTP SGPESGPTPA SAEQNE (1-195 aa encoded by B C066915)
MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein that localizes to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC). MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mac-MARCKS; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS-like 1; MARCKS-like protein 1; MARCKS-related protein
Gene Aliases: F52; MACMARCKS; MARCKSL1; MLP; MLP1; MRP
UniProt ID: (Human) P49006
Entrez Gene ID: (Human) 65108
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support