Proteintech

MAT2A Polyclonal Antibody

FIGURE: 1 / 3

MAT2A Antibody (55309-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 55309-1-AP) MAT2A antibody at dilution of 1:2,000 incubated at room temperature for 1.5 hours.

MAT2A Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

55309-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 8 publications 8 publications

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific to MATA2.

Target Information

The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m⁶A Modification of MAT2A Pre-mRNA by METTL16.

Oxidative medicine and cellular longevity

Chen PB,Shi GX,Liu T,Li B,Jiang SD,Zheng XF,Jiang LS

Tue Mar 08 00:00:00 EST 2022

Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m⁶A Modification of MAT2A Pre-mRNA by METTL16.

Oxidative medicine and cellular longevity

Chen PB,Shi GX,Liu T,Li B,Jiang SD,Zheng XF,Jiang LS

Tue Mar 08 00:00:00 EST 2022

M⁶A RNA Methylation Mediates NOD1/NF-kB Signaling Activation in the Liver of Piglets Challenged with Lipopolysaccharide.

Antioxidants (Basel, Switzerland)

Xu M,Zhuo R,Tao S,Liang Y,Liu C,Liu Q,Wang T,Zhong X

Fri Sep 30 00:00:00 EDT 2022

Time-restricted feeding mitigates obesity through adipocyte thermogenesis.

Science (New York, N.Y.)

Hepler C,Weidemann BJ,Waldeck NJ,Marcheva B,Cedernaes J,Thorne AK,Kobayashi Y,Nozawa R,Newman MV,Gao P,Shao M,Ramsey KM,Gupta RK,Bass J

Fri Oct 21 00:00:00 EDT 2022

Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Kang H,Guo Q,Dong Y,Peng R,Song K,Wang J,Liu H,Zhu M,Zhao H,Guan H,Li F

Tue Feb 01 00:00:00 EST 2022

Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Kang H,Guo Q,Dong Y,Peng R,Song K,Wang J,Liu H,Zhu M,Zhao H,Guan H,Li F

Tue Feb 01 00:00:00 EST 2022

The SESAME complex regulates cell senescence through the generation of acetyl-CoA.

Nature metabolism

Chen W,Yu X,Wu Y,Tang J,Yu Q,Lv X,Zha Z,Hu B,Li X,Chen J,Ma L,Workman JL,Li S

Thu Jul 01 00:00:00 EDT 2021

Activating transcription factor 4 regulates angiogenesis under lipid overload via methionine adenosyltransferase 2A-mediated endothelial epigenetic alteration.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chen L,Liu X,Zhou H,Li G,Huang F,Zhang J,Xia T,Lei W,Zhao J,Li C,Chen M

Tue Jun 01 00:00:00 EDT 2021

mTORC1 stimulates cell growth through SAM synthesis and m⁶A mRNA-dependent control of protein synthesis.

Molecular cell

Villa E,Sahu U,O'Hara BP,Ali ES,Helmin KA,Asara JM,Gao P,Singer BD,Ben-Sahra I

Thu May 20 00:00:00 EDT 2021

Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.

Environmental toxicology and pharmacology

Kuang W,Zhang X,Zhu W,Lan Z

Fri Sep 01 00:00:00 EDT 2017

Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.

Environmental toxicology and pharmacology

Kuang W,Zhang X,Zhu W,Lan Z

Fri Sep 01 00:00:00 EDT 2017

Bioinformatics

Protein Aliases: AdoMet synthase 2; adoMet synthetase 2; MAT 2; MAT-II; Methionine adenosyltransferase 2; Methionine adenosyltransferase II; methionine adenosyltransferase II, alpha; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2; testicular tissue protein Li 121

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Gene Aliases: AMS2; D630045P18Rik; MAT2A; MATA2; MATII; SAMS2

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UniProt ID: (Human) P31153, (Mouse) Q3THS6

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Entrez Gene ID: (Human) 4144, (Mouse) 232087

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Function(s)

methionine adenosyltransferase activity protein binding ATP binding metal ion binding nucleotide binding amino acid binding transferase activity nucleotidyltransferase

Process(es)

S-adenosylmethionine biosynthetic process one-carbon metabolic process methylation circadian rhythm response to hormone response to drug response to cAMP

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MAT2A Polyclonal Antibody

MAT2A Antibody (55309-1-AP) in WB

Product Details

55309-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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