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MATN2 Antibody (PA5-67622) in IHC (P)
Immunohistochemical analysis of MATN2 in paraffin-embedded Human colorectal cancer tissue using (left) MATN2 Polyclonal Antibody (Product # PA5-67622) at a 1:40 dilution and (right) is treated with synthetic peptide. (Original magnification: x200).
Product Details
PA5-67622
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human MATN2 (797-810).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2688532
Target Information
Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Matrilin-2; testis tissue sperm-binding protein Li 94mP
Gene Aliases: MATN2; UNQ193/PRO219
UniProt ID: (Human) O00339
Entrez Gene ID: (Human) 4147
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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