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Immunogen sequence: KEHGRNELFT DSECKEISEI TGGPINETLK LLLSSSEWVQ SEKLVRALQT PLMRLCAWYL YGEKHRGYAL NPVANFHLQN GAVLWRINWM ADVSLRGITG SCGLMANYRY FLEETGPNST SYLGSKIIKA SEQVLSLVAQ FQKNSKL
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
MCD catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: malonyl coenzyme A decarboxylase; Malonyl-CoA decarboxylase, mitochondrial; MCD
Gene Aliases: MCD; MLYCD
UniProt ID: (Human) O95822
Entrez Gene ID: (Human) 23417
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