Product References
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
Biochimica et biophysica acta. Molecular cell research
Zheng Z,Han L,Li Y,Chen Z,Yang W,Liu C,Tao M,Jiang Y,Ke X,Liu Y,Guo X
Tue Aug 01 00:00:00 EDT 2023
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
Biochimica et biophysica acta. Molecular cell research
Zheng Z,Han L,Li Y,Chen Z,Yang W,Liu C,Tao M,Jiang Y,Ke X,Liu Y,Guo X
Tue Aug 01 00:00:00 EDT 2023
Effect of 3D Spheroid Culturing on NF-κB Signaling Pathway and Neurogenic Potential in Human Amniotic Fluid Stem Cells.
International journal of molecular sciences
Valiulienė G,Zentelytė A,Beržanskytė E,Navakauskienė R
Fri Feb 10 00:00:00 EST 2023
Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates.
Developmental cell
Fu Y,Jia X,Yuan J,Yang Y,Zhang T,Yu Q,Zhou J,Wang T
Mon Mar 13 00:00:00 EDT 2023
Dihydroergotamine mesylate enhances the anti-tumor effect of sorafenib in liver cancer cells.
Biochemical pharmacology
He M,Liao Q,Liu D,Dai X,Shan M,Yang M,Zhang Y,Zhai L,Chen L,Xiang L,He M,Li S,Chen A,Sun L,Lian J
Mon May 01 00:00:00 EDT 2023
PARP1 controls the transcription of CD24 by ADP-ribosylating the RNA helicase DDX5 in pancreatic cancer.
The international journal of biochemistry & cell biology
Chen K,Dai M,Luo Q,Wang Y,Shen W,Liao Y,Zhou Y,Cheng W
Wed Feb 01 00:00:00 EST 2023
Venetoclax-Resistant T-ALL Cells Display Distinct Cancer Stem Cell Signatures and Enrichment of Cytokine Signaling.
International journal of molecular sciences
Shah K,Al Ashiri L,Nasimian A,Ahmed M,Kazi JU
Sun Mar 05 00:00:00 EST 2023
Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma.
Aging
Hsieh TY,Sung WW,Chang YC,Yu CY,Lu LY,Dong C,Lee TH,Chen SL
Fri Apr 21 00:00:00 EDT 2023
DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the NRF2/NQO1 axis.
Cellular signalling
Chu X,Zhong L,Dan W,Wang X,Zhang Z,Liu Z,Lu Y,Shao X,Zhou Z,Chen S,Liu B
Mon May 01 00:00:00 EDT 2023
Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway.
Journal of ethnopharmacology
Zhu Y,Han Q,Wang L,Wang B,Chen J,Cai B,Wu C,Zhu X,Liu F,Han D,Dong H,Jia Y,Liu Y
Mon Jan 30 00:00:00 EST 2023
Platycodin D induces proliferation inhibition and mitochondrial apoptosis in diffuse large B-cell lymphoma.
Experimental hematology
Liu P,Zhao M,Lin Y,Jiang X,Xia T,Li Y,Lu Y,Jiang L
Sat Jul 01 00:00:00 EDT 2023
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.
European journal of medicinal chemistry
Chen J,Zhao T,He F,Zhong Y,Wang S,Tang Z,Qiu Y,Wu Z,Fang M
Mon Jun 05 00:00:00 EDT 2023
Proscillaridin A Sensitizes Human Colon Cancer Cells to TRAIL-Induced Cell Death.
International journal of molecular sciences
Semba M,Takamatsu S,Komazawa-Sakon S,Miyoshi E,Nishiyama C,Nakano H,Moriwaki K
Thu Jun 23 00:00:00 EDT 2022
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
Apoptosis : an international journal on programmed cell death
Liu S,Qiao X,Wu S,Gai Y,Su Y,Edwards H,Wang Y,Lin H,Taub JW,Wang G,Ge Y
Thu Dec 01 00:00:00 EST 2022
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
Apoptosis : an international journal on programmed cell death
Liu S,Qiao X,Wu S,Gai Y,Su Y,Edwards H,Wang Y,Lin H,Taub JW,Wang G,Ge Y
Thu Dec 01 00:00:00 EST 2022
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Biochemical pharmacology
Zhao J,Chen S,Yang C,Zhou M,Yang T,Sun B,Zhu J,Zhang H,Lu Q,Li L,Yang Z,Song B,Shen W,Yi S,Dai S
Wed Jun 01 00:00:00 EDT 2022
CDK12 orchestrates super-enhancer-associated CCDC137 transcription to direct hepatic metastasis in colorectal cancer.
Clinical and translational medicine
Dai W,Wu J,Peng X,Hou W,Huang H,Cheng Q,Liu Z,Luyten W,Schoofs L,Zhou J,Liu S
Sat Oct 01 00:00:00 EDT 2022
Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.
Cancer research
Sela Y,Li J,Maheswaran S,Norgard R,Yuan S,Hubbi M,Doepner M,Xu JP,Ho ES,Mesaros C,Sheehan C,Croley G,Muir A,Blair IA,Shalem O,Dang CV,Stanger BZ
Mon May 16 00:00:00 EDT 2022
DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway.
Cell communication and signaling : CCS
Chu X,Zhong L,Dan W,Wang X,Zhang Z,Liu Z,Lu Y,Shao X,Zhou Z,Chen S,Liu B
Thu Oct 27 00:00:00 EDT 2022
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.
Frontiers in pharmacology
Zhou J,Wang Y,Zhang L,Chen Q,Zhu X,Jiang P,Jiang N,Zhao W,Li B
Sat Jul 16 00:00:00 EDT 2022
Inhibition of proteasomal deubiquitinases USP14 and UCHL5 overcomes tyrosine kinase inhibitor resistance in chronic myeloid leukaemia.
Clinical and translational medicine
Jiang L,He Q,Chen X,Liu A,Ding W,Zhang H,Chen X,Zhou H,Meng Y,Liu B,Peng G,Wang C,Liu J,Shi X
Thu Sep 01 00:00:00 EDT 2022
Metabolic Reprogramming Mediates Delayed Apoptosis of Human Neutrophils Infected With Francisella tularensis.
Frontiers in immunology
Krysa SJ,Allen LH
Tue Jun 14 00:00:00 EDT 2022
Addressing Doxorubicin Resistance in Bone Sarcomas Using Novel Drug-Resistant Models.
International journal of molecular sciences
Gallego B,Murillo D,Rey V,Huergo C,Estupiñán Ó,Rodríguez A,Tornín J,Rodríguez R
Wed Jun 08 00:00:00 EDT 2022
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
Experimental hematology
Liu F,Zhao Q,Su Y,Lv J,Gai Y,Liu S,Lin H,Wang Y,Wang G
Sat Jan 01 00:00:00 EST 2022
Combination of berberine and low glucose inhibits gastric cancer through the PP2A/GSK3β/MCL-1 signaling pathway.
European journal of pharmacology
Peng Z,Wangmu T,Li L,Han G,Huang D,Yi P
Thu May 05 00:00:00 EDT 2022
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Biochemical and biophysical research communications
Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H
Sat Feb 19 00:00:00 EST 2022
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Biochemical and biophysical research communications
Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H
Sat Feb 19 00:00:00 EST 2022
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Biochemical and biophysical research communications
Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H
Sat Feb 19 00:00:00 EST 2022
Identification and Validation of an Apoptosis-Related Gene Prognostic Signature for Oral Squamous Cell Carcinoma.
Frontiers in oncology
Wang S,Zhang S,Lin Z,Ma J,Zhu L,Liao G
Sat Jul 16 00:00:00 EDT 2022
Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage.
Developmental cell
Cao K,Riley JS,Heilig R,Montes-Gómez AE,Vringer E,Berthenet K,Cloix C,Elmasry Y,Spiller DG,Ichim G,Campbell KJ,Gilmore AP,Tait SWG
Mon May 23 00:00:00 EDT 2022
FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy.
Clinical and translational medicine
Ling X,Wu W,Aljahdali IAM,Liao J,Santha S,Fountzilas C,Boland PM,Li F
Sun May 01 00:00:00 EDT 2022
CircPVT1 promotes gallbladder cancer growth by sponging miR-339-3p and regulates MCL-1 expression.
Cell death discovery
Wang S,Su TT,Tong H,Shi W,Ma F,Quan Z
Mon Jul 26 00:00:00 EDT 2021
Loss of miR-1469 expression mediates melanoma cell migration and invasion.
PloS one
DiVincenzo MJ,Barricklow Z,Schwarz E,Moufawad M,Howard JH,Yu L,Chung C,Gru AA,Carson WE
Tue Nov 16 00:00:00 EST 2021
Pharmaceutical Drug Metformin and MCL1 Inhibitor S63845 Exhibit Anticancer Activity in Myeloid Leukemia Cells via Redox Remodeling.
Molecules (Basel, Switzerland)
Valiulienė G,Vitkevičienė A,Skliutė G,Borutinskaitė V,Navakauskienė R
Thu Apr 15 00:00:00 EDT 2021
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Nature communications
Hu D,Sun X,Magpusao A,Fedorov Y,Thompson M,Wang B,Lundberg K,Adams DJ,Qi X
Mon Sep 06 00:00:00 EDT 2021
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
Biochemical and biophysical research communications
Wang Q,Dong Z,Su J,Huang J,Xiao P,Tian L,Chen Y,Ma L,Chen X
Fri Apr 16 00:00:00 EDT 2021
The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
Haematologica
Li X,Su Y,Hege K,Madlambayan G,Edwards H,Knight T,Polin L,Kushner J,Dzinic SH,White K,Yang J,Miller R,Wang G,Zhao L,Wang Y,Lin H,Taub JW,Ge Y
Sat May 01 00:00:00 EDT 2021
The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
Haematologica
Li X,Su Y,Hege K,Madlambayan G,Edwards H,Knight T,Polin L,Kushner J,Dzinic SH,White K,Yang J,Miller R,Wang G,Zhao L,Wang Y,Lin H,Taub JW,Ge Y
Sat May 01 00:00:00 EDT 2021
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Journal of materials chemistry. B
Long Y,Wang Z,Fan J,Yuan L,Tong C,Zhao Y,Liu B
Wed May 12 00:00:00 EDT 2021
Interplay between protein acetylation and ubiquitination controls MCL1 protein stability.
Cell reports
Shimizu K,Gi M,Suzuki S,North BJ,Watahiki A,Fukumoto S,Asara JM,Tokunaga F,Wei W,Inuzuka H
Tue Nov 09 00:00:00 EST 2021
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.
Frontiers in molecular biosciences
Yang W,Feng Q,Li M,Su J,Wang P,Wang X,Yin Y,Wang X,Zhao M
Tue Jun 29 00:00:00 EDT 2021
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
Biomedical and environmental sciences : BES
Li MJ,Xiong D,Huang H,Wen ZY
Sat Feb 20 00:00:00 EST 2021
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Blood cancer journal
Qiao X,Ma J,Knight T,Su Y,Edwards H,Polin L,Li J,Kushner J,Dzinic SH,White K,Wang J,Lin H,Wang Y,Wang L,Wang G,Taub JW,Ge Y
Mon Jun 07 00:00:00 EDT 2021
Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell.
Molecular medicine reports
Chang L,Zhou R,He Y,Meng M,Hu J,Liu Y,Pan Y,Tang Z,Yue Z
Sun Aug 01 00:00:00 EDT 2021
Dichloroacetate enhances the anti-tumor effect of sorafenib via modulating the ROS-JNK-Mcl-1 pathway in liver cancer cells.
Experimental cell research
Sun L,Jiang Y,Yan X,Dai X,Huang C,Chen L,Li T,Zhang Y,Xiao H,Yang M,Xiang L,Zhang Y,Chen S,Li S,Chen A,He F,Lian J
Wed Sep 01 00:00:00 EDT 2021
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Molecular immunology
Xu Y,Yu J,Ma C,Gong Z,Wu X,Deng G
Mon Feb 01 00:00:00 EST 2021
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Archives of pharmacal research
Wang J,Su Q,Wu Q,Chen K,Ullah A,Ghauri MA,Zhang Y
Mon Nov 01 00:00:00 EDT 2021
SRT2183 impairs ovarian cancer by facilitating autophagy.
Aging
Sun T,Hu Y,He W,Shang Y,Yang X,Gong L,Zhang X,Gong P,Yang G
Fri Nov 20 00:00:00 EST 2020
Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway.
Life sciences
Liu Y,Wang H,Liu N,Du J,Lan X,Qi X,Zhuang C,Sun T,Li Y,Yu J
Sat Aug 01 00:00:00 EDT 2020
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu X,Xia M,Wang J,Yu H,Chai J,Zhang Z,Sun Y,Su J,Sun L
Tue Sep 01 00:00:00 EDT 2020
Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu X,Xia M,Wang J,Yu H,Chai J,Zhang Z,Sun Y,Su J,Sun L
Tue Sep 01 00:00:00 EDT 2020
Long Non-coding RNA CCAT1 Acts as an Oncogene and Promotes Sunitinib Resistance in Renal Cell Carcinoma.
Frontiers in oncology
Shan L,Liu W,Zhan Y
Fri Sep 08 00:00:00 EDT 2023
ALG-2 couples T cell activation and apoptosis by regulating proteasome activity and influencing MCL1 stability.
Cell death & disease
He TS,Ji W,Zhang J,Lu J,Liu X
Thu Jan 02 00:00:00 EST 2020
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
OncoTargets and therapy
Huang G,Chen J,Liu J,Zhang X,Duan H,Fang Q
Sun Apr 17 00:00:00 EDT 2022
CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
Journal of cellular and molecular medicine
Hu C,Xia H,Bai S,Zhao J,Edwards H,Li X,Yang Y,Lyu J,Wang G,Zhan Y,Dong Y,Ge Y
Wed Jul 01 00:00:00 EDT 2020
Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis.
Toxicology in vitro : an international journal published in association with BIBRA
Su Q,Wang J,Liu F,Zhang Y
Sat Aug 01 00:00:00 EDT 2020
Downregulation of CDC20 Increases Radiosensitivity through Mcl-1/p-Chk1-Mediated DNA Damage and Apoptosis in Tumor Cells.
International journal of molecular sciences
Gao Y,Wen P,Chen B,Hu G,Wu L,Xu A,Zhao G
Sat Sep 12 00:00:00 EDT 2020
Targeting of β-Catenin Reverses Radioresistance of Cervical Cancer with the PIK3CA-E545K Mutation.
Molecular cancer therapeutics
Jiang W,Wu Y,He T,Zhu H,Ke G,Xiang L,Yang H
Sat Feb 01 00:00:00 EST 2020
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway.
Oncology reports
Yan X,Yang C,Hu W,Chen T,Wang Q,Pan F,Qiu B,Tang B
Wed Jul 01 00:00:00 EDT 2020
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu YC,Tsai JJ,Weng YS,Hsu FT
Sat Aug 01 00:00:00 EDT 2020
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu YC,Tsai JJ,Weng YS,Hsu FT
Sat Aug 01 00:00:00 EDT 2020
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.
Nature communications
Munkhbaatar E,Dietzen M,Agrawal D,Anton M,Jesinghaus M,Boxberg M,Pfarr N,Bidola P,Uhrig S,Höckendorf U,Meinhardt AL,Wahida A,Heid I,Braren R,Mishra R,Warth A,Muley T,Poh PSP,Wang X,Fröhling S,Steiger K,Slotta-Huspenina J,van Griensven M,Pfeiffer F,Lange S,Rad R,Spella M,Stathopoulos GT,Ruland J,Bassermann F,Weichert W,Strasser A,Branca C,Heikenwalder M,Swanton C,McGranahan N,Jost PJ
Thu Sep 10 00:00:00 EDT 2020
Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation.
The Journal of biological chemistry
Nagareddy B,Khan A,Kim H
Fri Oct 02 00:00:00 EDT 2020
Chaetomugilin J Enhances Apoptosis in Human Ovarian Cancer A2780 Cells Induced by Cisplatin Through Inhibiting Pink1/Parkin Mediated Mitophagy.
OncoTargets and therapy
Hu X,Wang J,Chai J,Yu X,Zhang Y,Feng Y,Qin J,Yu H
Sun Apr 17 00:00:00 EDT 2022
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Journal of experimental & clinical cancer research : CR
Li C,Deng C,Pan G,Wang X,Zhang K,Dong Z,Zhao G,Tan M,Hu X,Shi S,Du J,Ji H,Wang X,Yang L,Cui H
Fri Oct 30 00:00:00 EDT 2020
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Journal of experimental & clinical cancer research : CR
Li C,Deng C,Pan G,Wang X,Zhang K,Dong Z,Zhao G,Tan M,Hu X,Shi S,Du J,Ji H,Wang X,Yang L,Cui H
Fri Oct 30 00:00:00 EDT 2020
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Journal of experimental & clinical cancer research : CR
Li C,Deng C,Pan G,Wang X,Zhang K,Dong Z,Zhao G,Tan M,Hu X,Shi S,Du J,Ji H,Wang X,Yang L,Cui H
Fri Oct 30 00:00:00 EDT 2020
ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3.
Oncogene
Li YL,Wu LW,Zeng LH,Zhang ZY,Wang W,Zhang C,Lin NM
Tue Sep 01 00:00:00 EDT 2020
Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
Acta pharmacologica Sinica
Liu YQ,Wang SK,Xu QQ,Yuan HQ,Guo YX,Wang Q,Kong F,Lin ZM,Sun DQ,Wang RM,Lou HX
Wed May 01 00:00:00 EDT 2019
Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
Acta pharmacologica Sinica
Liu YQ,Wang SK,Xu QQ,Yuan HQ,Guo YX,Wang Q,Kong F,Lin ZM,Sun DQ,Wang RM,Lou HX
Wed May 01 00:00:00 EDT 2019
Protein kinase RNA-like ER kinase/eukaryotic translation initiation factor 2α pathway attenuates tumor necrosis factor alpha-induced apoptosis in nucleus pulposus cells by activating autophagy.
Journal of cellular physiology
Chen L,Liu L,Xie ZY,Wang F,Zhu L,Zhang C,Fan P,Sinkemani A,Hong X,Wu XT
Mon Jul 01 00:00:00 EDT 2019
Protein kinase RNA-like ER kinase/eukaryotic translation initiation factor 2α pathway attenuates tumor necrosis factor alpha-induced apoptosis in nucleus pulposus cells by activating autophagy.
Journal of cellular physiology
Chen L,Liu L,Xie ZY,Wang F,Zhu L,Zhang C,Fan P,Sinkemani A,Hong X,Wu XT
Mon Jul 01 00:00:00 EDT 2019
The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis.
EBioMedicine
Chen P,Wang B,Mo Q,Wu P,Fang Y,Tian Y,Jin X,Gao Y,Wu Y,Cao Y,Zhang Y,Xi L,Wang S,Hu J,Ma D,Zhou J,Gao Q,Chen G
Fri Nov 01 00:00:00 EDT 2019
Secalonic Acid-F, a Novel Mycotoxin, Represses the Progression of Hepatocellular Carcinoma via MARCH1 Regulation of the PI3K/AKT/β-catenin Signaling Pathway.
Molecules (Basel, Switzerland)
Xie L,Li M,Liu D,Wang X,Wang P,Dai H,Yang W,Liu W,Hu X,Zhao M
Tue Jan 22 00:00:00 EST 2019
MARCH1 encourages tumour progression of hepatocellular carcinoma via regulation of PI3K-AKT-β-catenin pathways.
Journal of cellular and molecular medicine
Xie L,Dai H,Li M,Yang W,Yu G,Wang X,Wang P,Liu W,Hu X,Zhao M
Wed May 01 00:00:00 EDT 2019
The deubiquitinating enzyme OTUD1 antagonizes BH3-mimetic inhibitor induced cell death through regulating the stability of the MCL1 protein.
Cancer cell international
Wu L,Lin Y,Feng J,Qi Y,Wang X,Lin Q,Shi W,Zheng E,Wang W,Hou Z,Lin H,Yu C,He Y,Xu Y,Yang H,Lin L,Li L
Sun Apr 10 00:00:00 EDT 2022
Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck.
Cell death & disease
Carter RJ,Milani M,Butterworth M,Alotibi A,Harper N,Yedida G,Greaves G,Al-Zebeeby A,Jorgensen AL,Schache AG,Risk JM,Shaw RJ,Jones TM,Sacco JJ,Hurlstone A,Cohen GM,Varadarajan S
Wed Dec 04 00:00:00 EST 2019
IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation.
Nature communications
Kumaran Satyanarayanan S,El Kebir D,Soboh S,Butenko S,Sekheri M,Saadi J,Peled N,Assi S,Othman A,Schif-Zuck S,Feuermann Y,Barkan D,Sher N,Filep JG,Ariel A
Fri Aug 02 00:00:00 EDT 2019
Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ma J,Zhao S,Qiao X,Knight T,Edwards H,Polin L,Kushner J,Dzinic SH,White K,Wang G,Zhao L,Lin H,Wang Y,Taub JW,Ge Y
Fri Nov 15 00:00:00 EST 2019
Venetoclax Synergistically Enhances the Anti-leukemic Activity of Vosaroxin Against Acute Myeloid Leukemia Cells Ex Vivo.
Targeted oncology
Liu F,Knight T,Su Y,Edwards H,Wang G,Wang Y,Taub JW,Lin H,Sun L,Ge Y
Sat Jun 01 00:00:00 EDT 2019
CircRNA_014511 affects the radiosensitivity of bone marrow mesenchymal stem cells by binding to miR-29b-2-5p.
Bosnian journal of basic medical sciences
Wang Y,Zhang J,Li J,Gui R,Nie X,Huang R
Mon May 20 00:00:00 EDT 2019
Alkaloids from Piper nigrum Synergistically Enhanced the Effect of Paclitaxel against Paclitaxel-Resistant Cervical Cancer Cells through the Downregulation of Mcl-1.
Journal of agricultural and food chemistry
Xie Z,Wei Y,Xu J,Lei J,Yu J
Wed May 08 00:00:00 EDT 2019
Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo.
Biochemical pharmacology
Su Y,Li X,Ma J,Zhao J,Liu S,Wang G,Edwards H,Taub JW,Lin H,Ge Y
Thu Feb 01 00:00:00 EST 2018
Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo.
Biochemical pharmacology
Su Y,Li X,Ma J,Zhao J,Liu S,Wang G,Edwards H,Taub JW,Lin H,Ge Y
Thu Feb 01 00:00:00 EST 2018
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Cancer biology & therapy
Yin S,Du W,Wang F,Han B,Cui Y,Yang D,Chen H,Liu D,Liu X,Zhai X,Jiang C
Tue Apr 03 00:00:00 EDT 2018
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Cancer biology & therapy
Yin S,Du W,Wang F,Han B,Cui Y,Yang D,Chen H,Liu D,Liu X,Zhai X,Jiang C
Tue Apr 03 00:00:00 EDT 2018
EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway.
Oncology reports
Huang R,Liu H,Chen Y,He Y,Kang Q,Tu S,He Y,Zhou X,Wang L,Yang J,Wu A,Li Y
Mon Jan 01 00:00:00 EST 2018
EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway.
Oncology reports
Huang R,Liu H,Chen Y,He Y,Kang Q,Tu S,He Y,Zhou X,Wang L,Yang J,Wu A,Li Y
Mon Jan 01 00:00:00 EST 2018
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Wang X,Liu W,Wang P,Li S
Thu Nov 01 00:00:00 EDT 2018
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Wang X,Liu W,Wang P,Li S
Thu Nov 01 00:00:00 EDT 2018
Natural Compound Methyl Protodioscin Suppresses Proliferation and Inhibits Glycolysis in Pancreatic Cancer.
Evidence-based complementary and alternative medicine : eCAM
Chen L,Cheng CS,Gao H,Zhan L,Wang F,Qu C,Li Y,Wang P,Chen H,Meng Z,Liu L,Chen H,Chen Z
Wed Sep 30 00:00:00 EDT 2020
Natural Compound Methyl Protodioscin Suppresses Proliferation and Inhibits Glycolysis in Pancreatic Cancer.
Evidence-based complementary and alternative medicine : eCAM
Chen L,Cheng CS,Gao H,Zhan L,Wang F,Qu C,Li Y,Wang P,Chen H,Meng Z,Liu L,Chen H,Chen Z
Wed Sep 30 00:00:00 EDT 2020
A Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells.
Stem cell reports
Rasmussen ML,Kline LA,Park KP,Ortolano NA,Romero-Morales AI,Anthony CC,Beckermann KE,Gama V
Tue Mar 13 00:00:00 EDT 2018
A Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells.
Stem cell reports
Rasmussen ML,Kline LA,Park KP,Ortolano NA,Romero-Morales AI,Anthony CC,Beckermann KE,Gama V
Tue Mar 13 00:00:00 EDT 2018
MCL-1 is a prognostic indicator and drug target in breast cancer.
Cell death & disease
Campbell KJ,Dhayade S,Ferrari N,Sims AH,Johnson E,Mason SM,Dickson A,Ryan KM,Kalna G,Edwards J,Tait SWG,Blyth K
Tue Jan 16 00:00:00 EST 2018
MCL-1 is a prognostic indicator and drug target in breast cancer.
Cell death & disease
Campbell KJ,Dhayade S,Ferrari N,Sims AH,Johnson E,Mason SM,Dickson A,Ryan KM,Kalna G,Edwards J,Tait SWG,Blyth K
Tue Jan 16 00:00:00 EST 2018
MCL-1 is a prognostic indicator and drug target in breast cancer.
Cell death & disease
Campbell KJ,Dhayade S,Ferrari N,Sims AH,Johnson E,Mason SM,Dickson A,Ryan KM,Kalna G,Edwards J,Tait SWG,Blyth K
Tue Jan 16 00:00:00 EST 2018
MCL-1 is a prognostic indicator and drug target in breast cancer.
Cell death & disease
Campbell KJ,Dhayade S,Ferrari N,Sims AH,Johnson E,Mason SM,Dickson A,Ryan KM,Kalna G,Edwards J,Tait SWG,Blyth K
Tue Jan 16 00:00:00 EST 2018
Chemical and genetic inhibition of STAT3 sensitizes hepatocellular carcinoma cells to sorafenib induced cell death.
International journal of biological sciences
Xie L,Zeng Y,Dai Z,He W,Ke H,Lin Q,Chen Y,Bu J,Lin D,Zheng M
Mon Jul 15 00:00:00 EDT 2019
Chemical and genetic inhibition of STAT3 sensitizes hepatocellular carcinoma cells to sorafenib induced cell death.
International journal of biological sciences
Xie L,Zeng Y,Dai Z,He W,Ke H,Lin Q,Chen Y,Bu J,Lin D,Zheng M
Mon Jul 15 00:00:00 EDT 2019
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.
Experimental biology and medicine (Maywood, N.J.)
Gao C,Sun R,Xie YR,Jiang AL,Lin M,Li M,Chen ZW,Zhang P,Jin H,Feng JP
Mon May 01 00:00:00 EDT 2017
The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.
Experimental biology and medicine (Maywood, N.J.)
Gao C,Sun R,Xie YR,Jiang AL,Lin M,Li M,Chen ZW,Zhang P,Jin H,Feng JP
Mon May 01 00:00:00 EDT 2017
Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate.
Oncology letters
Huang W,Ren C,Huang G,Liu J,Liu W,Wang L,Zhu B,Feng X,Shi J,Li J,Xia X,Jia W,Chen J,Chen Y,Jiang X
Wed Feb 01 00:00:00 EST 2017
Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate.
Oncology letters
Huang W,Ren C,Huang G,Liu J,Liu W,Wang L,Zhu B,Feng X,Shi J,Li J,Xia X,Jia W,Chen J,Chen Y,Jiang X
Wed Feb 01 00:00:00 EST 2017
Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation.
Cell death & disease
Lu L,Zhang S,Li C,Zhou C,Li D,Liu P,Huang M,Shen X
Thu May 11 00:00:00 EDT 2017
Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation.
Cell death & disease
Lu L,Zhang S,Li C,Zhou C,Li D,Liu P,Huang M,Shen X
Thu May 11 00:00:00 EDT 2017
Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy.
Oncotarget
Feng T,Cao W,Shen W,Zhang L,Gu X,Guo Y,Tsai HI,Liu X,Li J,Zhang J,Li S,Wu F,Liu Y
Tue Jan 03 00:00:00 EST 2017
Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy.
Oncotarget
Feng T,Cao W,Shen W,Zhang L,Gu X,Guo Y,Tsai HI,Liu X,Li J,Zhang J,Li S,Wu F,Liu Y
Tue Jan 03 00:00:00 EST 2017
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Journal of experimental & clinical cancer research : CR
Yao S,Xu F,Chen Y,Ge Y,Zhang F,Huang H,Li L,Lin D,Luo X,Xu J,Luo D,Zhu X,Liu Y
Tue Jan 10 00:00:00 EST 2017
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Journal of experimental & clinical cancer research : CR
Yao S,Xu F,Chen Y,Ge Y,Zhang F,Huang H,Li L,Lin D,Luo X,Xu J,Luo D,Zhu X,Liu Y
Tue Jan 10 00:00:00 EST 2017
Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis.
Oncotarget
Li C,Miao R,Liu S,Wan Y,Zhang S,Deng Y,Bi J,Qu K,Zhang J,Liu C
Tue Apr 25 00:00:00 EDT 2017
Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis.
Oncotarget
Li C,Miao R,Liu S,Wan Y,Zhang S,Deng Y,Bi J,Qu K,Zhang J,Liu C
Tue Apr 25 00:00:00 EDT 2017
Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer.
Oncotarget
Ning C,Liang M,Liu S,Wang G,Edwards H,Xia Y,Polin L,Dyson G,Taub JW,Mohammad RM,Azmi AS,Zhao L,Ge Y
Tue Jul 04 00:00:00 EDT 2017
Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer.
Oncotarget
Ning C,Liang M,Liu S,Wang G,Edwards H,Xia Y,Polin L,Dyson G,Taub JW,Mohammad RM,Azmi AS,Zhao L,Ge Y
Tue Jul 04 00:00:00 EDT 2017
Demethylzeylasteral inhibits cell proliferation and induces apoptosis through suppressing MCL1 in melanoma cells.
Cell death & disease
Zhao Y,He J,Li J,Peng X,Wang X,Dong Z,Zhao E,Liu Y,Wu Z,Cui H
Thu Oct 26 00:00:00 EDT 2017
Demethylzeylasteral inhibits cell proliferation and induces apoptosis through suppressing MCL1 in melanoma cells.
Cell death & disease
Zhao Y,He J,Li J,Peng X,Wang X,Dong Z,Zhao E,Liu Y,Wu Z,Cui H
Thu Oct 26 00:00:00 EDT 2017
Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma.
Oncotarget
Zheng M,Xu H,Liao XH,Chen CP,Zhang AL,Lu W,Wang L,Yang D,Wang J,Liu H,Zhou XZ,Lu KP
Tue May 02 00:00:00 EDT 2017
Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma.
Oncotarget
Zheng M,Xu H,Liao XH,Chen CP,Zhang AL,Lu W,Wang L,Yang D,Wang J,Liu H,Zhou XZ,Lu KP
Tue May 02 00:00:00 EDT 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 EDT 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 EDT 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 EDT 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 EDT 2017
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Theranostics
Wei WJ,Sun ZK,Shen CT,Song HJ,Zhang XY,Qiu ZL,Luo QY
Mon Oct 23 00:00:00 EDT 2017
Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
Theranostics
Wei WJ,Sun ZK,Shen CT,Song HJ,Zhang XY,Qiu ZL,Luo QY
Mon Oct 23 00:00:00 EDT 2017
The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer.
Journal of cellular and molecular medicine
Wang SH,Zhang WJ,Wu XC,Weng MZ,Zhang MD,Cai Q,Zhou D,Wang JD,Quan ZW
Thu Dec 01 00:00:00 EST 2016
The lncRNA MALAT1 functions as a competing endogenous RNA to regulate MCL-1 expression by sponging miR-363-3p in gallbladder cancer.
Journal of cellular and molecular medicine
Wang SH,Zhang WJ,Wu XC,Weng MZ,Zhang MD,Cai Q,Zhou D,Wang JD,Quan ZW
Thu Dec 01 00:00:00 EST 2016
HDAC6 promotes cell proliferation and confers resistance to gefitinib in lung adenocarcinoma.
Oncology reports
Wang Z,Tang F,Hu P,Wang Y,Gong J,Sun S,Xie C
Fri Jul 01 00:00:00 EDT 2016
HDAC6 promotes cell proliferation and confers resistance to gefitinib in lung adenocarcinoma.
Oncology reports
Wang Z,Tang F,Hu P,Wang Y,Gong J,Sun S,Xie C
Fri Jul 01 00:00:00 EDT 2016
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Oncology reports
Wei WJ,Shen CT,Song HJ,Qiu ZL,Luo QY
Thu Sep 01 00:00:00 EDT 2016
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib.
Oncology reports
Wei WJ,Shen CT,Song HJ,Qiu ZL,Luo QY
Thu Sep 01 00:00:00 EDT 2016
Francisella tularensis Modulates a Distinct Subset of Regulatory Factors and Sustains Mitochondrial Integrity to Impair Human Neutrophil Apoptosis.
Journal of innate immunity
McCracken JM,Kinkead LC,McCaffrey RL,Allen LA
Fri Sep 22 00:00:00 EDT 2017
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dai B,Wang W,Liu R,Wang H,Zhang Y
Sun Mar 01 00:00:00 EST 2015
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dai B,Wang W,Liu R,Wang H,Zhang Y
Sun Mar 01 00:00:00 EST 2015
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Xiang M,Su H,Hong Z,Yang T,Shu G
Mon Jun 01 00:00:00 EDT 2015
17-Demethoxy-reblastatin, an Hsp90 inhibitor, induces mitochondria-mediated apoptosis through downregulation of Mcl-1 in human hepatocellular carcinoma cells.
Journal of bioenergetics and biomembranes
Zhao S,Li H,Jiang C,Ma T,Wu C,Huo Q,Liu H
Thu Oct 01 00:00:00 EDT 2015
17-Demethoxy-reblastatin, an Hsp90 inhibitor, induces mitochondria-mediated apoptosis through downregulation of Mcl-1 in human hepatocellular carcinoma cells.
Journal of bioenergetics and biomembranes
Zhao S,Li H,Jiang C,Ma T,Wu C,Huo Q,Liu H
Thu Oct 01 00:00:00 EDT 2015
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Medical oncology (Northwood, London, England)
Huang W,Liu J,Feng X,Chen H,Zeng L,Huang G,Liu W,Wang L,Jia W,Chen J,Ren C
Wed Apr 01 00:00:00 EDT 2015
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Medical oncology (Northwood, London, England)
Huang W,Liu J,Feng X,Chen H,Zeng L,Huang G,Liu W,Wang L,Jia W,Chen J,Ren C
Wed Apr 01 00:00:00 EDT 2015
Hexokinase II inhibitor, 3-BrPA induced autophagy by stimulating ROS formation in human breast cancer cells.
Genes & cancer
Zhang Q,Zhang Y,Zhang P,Chao Z,Xia F,Jiang C,Zhang X,Jiang Z,Liu H
Sat Mar 01 00:00:00 EST 2014
Hexokinase II inhibitor, 3-BrPA induced autophagy by stimulating ROS formation in human breast cancer cells.
Genes & cancer
Zhang Q,Zhang Y,Zhang P,Chao Z,Xia F,Jiang C,Zhang X,Jiang Z,Liu H
Sat Mar 01 00:00:00 EST 2014
Rapamycin interacts synergistically with idarubicin to induce T-leukemia cell apoptosis in vitro and in a mesenchymal stem cell simulated drug-resistant microenvironment via Akt/mammalian target of rapamycin and extracellular signal-related kinase signaling pathways.
Leukemia & lymphoma
Wu KN,Zhao YM,He Y,Wang BS,Du KL,Fu S,Hu KM,Zhang LF,Liu LZ,Hu YX,Wang YJ,Huang H
Sat Mar 01 00:00:00 EST 2014
Rapamycin interacts synergistically with idarubicin to induce T-leukemia cell apoptosis in vitro and in a mesenchymal stem cell simulated drug-resistant microenvironment via Akt/mammalian target of rapamycin and extracellular signal-related kinase signaling pathways.
Leukemia & lymphoma
Wu KN,Zhao YM,He Y,Wang BS,Du KL,Fu S,Hu KM,Zhang LF,Liu LZ,Hu YX,Wang YJ,Huang H
Sat Mar 01 00:00:00 EST 2014
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
International journal of molecular sciences
Wu X,Deng G,Hao X,Li Y,Zeng J,Ma C,He Y,Liu X,Wang Y
Fri Mar 21 00:00:00 EDT 2014
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
International journal of molecular sciences
Wu X,Deng G,Hao X,Li Y,Zeng J,Ma C,He Y,Liu X,Wang Y
Fri Mar 21 00:00:00 EDT 2014
Revisiting the role of MCL1 in tumorigenesis of solid cancer: gene expression correlates with antiproliferative phenotype in breast cancer cells and its functional regulatory variants are associated with reduced cancer susceptibility.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Wang S,Jiang Y,Liu J,Zhao Y,Xiang C,Ma R,Gao H,Jin L,He F,Wang H
Fri Aug 01 00:00:00 EDT 2014
Revisiting the role of MCL1 in tumorigenesis of solid cancer: gene expression correlates with antiproliferative phenotype in breast cancer cells and its functional regulatory variants are associated with reduced cancer susceptibility.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Wang S,Jiang Y,Liu J,Zhao Y,Xiang C,Ma R,Gao H,Jin L,He F,Wang H
Fri Aug 01 00:00:00 EDT 2014
Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in nonsmokers: implications for context-dependent phenotype of an antiapoptotic and antiproliferative gene in solid tumor.
Cancer
Jiang Y,Wang W,Wang J,Lu Y,Chen Y,Jin L,Lin D,He F,Wang H
Sun Apr 15 00:00:00 EDT 2012
Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in nonsmokers: implications for context-dependent phenotype of an antiapoptotic and antiproliferative gene in solid tumor.
Cancer
Jiang Y,Wang W,Wang J,Lu Y,Chen Y,Jin L,Lin D,He F,Wang H
Sun Apr 15 00:00:00 EDT 2012
Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in nonsmokers: implications for context-dependent phenotype of an antiapoptotic and antiproliferative gene in solid tumor.
Cancer
Jiang Y,Wang W,Wang J,Lu Y,Chen Y,Jin L,Lin D,He F,Wang H
Sun Apr 15 00:00:00 EDT 2012
Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in nonsmokers: implications for context-dependent phenotype of an antiapoptotic and antiproliferative gene in solid tumor.
Cancer
Jiang Y,Wang W,Wang J,Lu Y,Chen Y,Jin L,Lin D,He F,Wang H
Sun Apr 15 00:00:00 EDT 2012
N-α-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression.
Carcinogenesis
Xu H,Jiang B,Meng L,Ren T,Zeng Y,Wu J,Qu L,Shou C
Fri Jun 01 00:00:00 EDT 2012
N-α-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression.
Carcinogenesis
Xu H,Jiang B,Meng L,Ren T,Zeng Y,Wu J,Qu L,Shou C
Fri Jun 01 00:00:00 EDT 2012
Silencing prion protein in MDA-MB-435 breast cancer cells leads to pleiotropic cellular responses to cytotoxic stimuli.
PloS one
Yu G,Jiang L,Xu Y,Guo H,Liu H,Zhang Y,Yang H,Yuan C,Ma J
Tue May 07 00:00:00 EDT 2013
Silencing prion protein in MDA-MB-435 breast cancer cells leads to pleiotropic cellular responses to cytotoxic stimuli.
PloS one
Yu G,Jiang L,Xu Y,Guo H,Liu H,Zhang Y,Yang H,Yuan C,Ma J
Tue May 07 00:00:00 EDT 2013
Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma.
The Journal of biological chemistry
Gong K,Chen C,Zhan Y,Chen Y,Huang Z,Li W
Fri Oct 12 00:00:00 EDT 2012
Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma.
The Journal of biological chemistry
Gong K,Chen C,Zhan Y,Chen Y,Huang Z,Li W
Fri Oct 12 00:00:00 EDT 2012
