Proteintech

MCT1 Polyclonal Antibody

MCT1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 19

MCT1 Antibody (20139-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using 20139-1-AP (MCT1 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

MCT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MCT1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

20139-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 33 publications 33 publications

Immunohistochemistry (IHC)

View 16 publications 16 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 6 publications 6 publications

Flow Cytometry (Flow)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Bovine, Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MCT1 Fusion Protein Ag14098 (451-500 aa encoded by BC026317)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EQKANEQKK ESKEEETSID VAGKPNEVTK AAESPDQKDT DGGPKEEESP V (451-500 aa encoded by BC026317)

Target Information

SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners.

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Thu Oct 19 00:00:00 EDT 2023

Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis.

bioRxiv : the preprint server for biology

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Monocarboxylate transporter 1 is a novel target for breast cancer stem like-cell inhibition by diallyl trisulfide.

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