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Invitrogen
ME1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
ME1 Antibody (PA5-82251)
Relative expression in different tissues in IHC: Detection of differential expression levels of ME1 demonstrates antibody specificity. Immunohistochemical analysis of ME1 using anti-ME1 Polyclonal Antibody (Product #PA5-82251), shows significant staining of ME1 in adrenal gland and shows minimal or weak staining in kidney tissues. The relative expression levels of ME1 within each tissue is shown using RNA-... View More
Product Details
PA5-82251
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ME1. Recombinant protein control fragment (Product #RP-88951).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789411
Product Specific Information
Immunogen sequence: RITKNKLSDQ TILFQGAGEA ALGIAHLIVM ALEKEGLPKE KAIKKIWLVD SKGLIVKGRA SLTQEKEKFA HEHEEMKNLE AIVQEIKPTA LIGVAAIGGA FSEQILKDMA AFNERPIIFA LSNPTSKAEC
Target Information
ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Malic enzyme 1; malic enzyme 1, NADP(+)-dependent, cytosolic; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; NADP-dependent malic enzyme; NADP-ME; pyruvic-malic carboxylase
Gene Aliases: HUMNDME; ME1; MES
UniProt ID: (Human) P48163
Entrez Gene ID: (Human) 4199
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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