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Product Details
68117-1-IG150UL
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2G9G9
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytosolic malic enzyme 1; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+); malate dehydrogenase decarboxylase (NADP+); Malic enzyme 1; malic enzyme 1, NADP(+)-dependent, cytosolic; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; malic enzyme, supernatant; NADP-dependent malic enzyme; NADP-ME; pyruvic-malic carboxylase
Gene Aliases: D9Ertd267e; HUMNDME; Mdh-1; ME1; MES; Mod-1; MOD1
UniProt ID: (Human) P48163, (Mouse) P06801
Entrez Gene ID: (Human) 4199, (Pig) 397538, (Rabbit) 100355457, (Mouse) 17436, (Rat) 24552
malic enzyme activity
malate dehydrogenase (decarboxylating) (NAD+) activity
malate dehydrogenase (decarboxylating) (NADP+) activity
oxaloacetate decarboxylase activity
electron carrier activity
manganese ion binding
ADP binding
NADP binding
NAD binding
protein binding
oxidoreductase activity
metal ion binding
oxidoreductase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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