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Product Details
PA5-86177
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, corresponding to amino acids 280-330 of Human MEF-2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2802970
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A); Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
Gene Aliases: A430079H05Rik; ADCAD1; MEF2; MEF2A; RSRFC4; RSRFC9
UniProt ID: (Human) Q02078, (Mouse) Q60929, (Rat) Q2MJT0
Entrez Gene ID: (Human) 4205, (Mouse) 17258, (Rat) 309957
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II transcription coactivator activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein kinase binding
activating transcription factor binding
histone acetyltransferase binding
histone deacetylase binding
sequence-specific DNA binding
SMAD binding
protein heterodimerization activity
DNA binding
protein dimerization activity
MADS box transcription factor
mitochondrial genome maintenance
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
heart development
muscle organ development
positive regulation of cardiac muscle hypertrophy
positive regulation of transcription from RNA polymerase II promoter
mitochondrion distribution
dendrite morphogenesis
positive regulation of muscle cell differentiation
ventricular cardiac myofibril assembly
cardiac conduction
ERK5 cascade
cellular response to calcium ion
regulation of transcription, DNA-templated
multicellular organism development
nervous system development
cell differentiation
positive regulation of transcription, DNA-templated
cellular response to glucose stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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