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Invitrogen
MEOX2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-62841
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MEOX2. Recombinant protein control fragment (Product #RP-100059).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2643874
Product Specific Information
Immunogen sequence: QQHQALQTNW HLPQMSSPPS AARHSLCLQP DSGGPPELGS SPPVLCSNSS SLGSSTPTGA ACAPGDYGRQ ALSPAEAEKR SGGKR
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
Target Information
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Growth arrest-specific homeobox; Homeobox protein MOX-2; Mesenchyme homeobox 2
Gene Aliases: GAX; MEOX2; MOX2
UniProt ID: (Human) P50222
Entrez Gene ID: (Human) 4223
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
angiogenesis
somite specification
transcription from RNA polymerase II promoter
multicellular organism development
skeletal muscle tissue development
blood circulation
positive regulation of transcription from RNA polymerase II promoter
palate development
limb development
neuron death
negative regulation of cell migration involved in sprouting angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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