Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MVRRDRLRR MREWWVQVGL LAVPLLAAYL HIPPPQLSPA LHSWKSSGKF FTYKGLRIFY QDSVGVVGSP EIVVLLHGFP TSSYDWYKIW EGLTLRFHRV IALDFLGFGF SDKPRPHHYS IFEQASIVEA LLRHLGLQNR RINLLSHDYG DIVAQELLYR YKQNRSGRLT IKSLCLSNGG IFPETHRPLL LQKLLKDGGV LSPILTRLMN FFVFSRGLTP VFGPYTRPSE SELWD (1-234 aa encoded by BC011908)
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686L18234; Mesoderm-specific transcript homolog protein; Mesoderm-specific transcript protein; MGC111102; MGC8703; Paternally-expressed gene 1 protein
Gene Aliases: 121a; AA408879; AI256745; MEST; PEG1
UniProt ID: (Human) Q5EB52, (Mouse) Q07646
Entrez Gene ID: (Human) 4232, (Mouse) 17294
Molecular Function:
serine protease
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